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Global research trends and prospects of cellular metabolism in colorectal cancer

World Journal of Gastrointestinal Oncology 2024年第2期16卷 527-542页

作者： yan-Chen Liu Zhi-Cheng Gong Chao-Qun Li Peng Teng yan-yan Chen Zhao-hui Huang Wuxi Cancer Institute Affiliated Hospital of Jiangnan UniversityWuxi 214122Jiangsu ProvinceChina Wuxi School of Medicine Jiangnan UniversityWuxi 214122Jiangsu ProvinceChina Wuxi Institute of Integrated Chinese and Western Medicine Affiliated Hospital of Jiangnan UniversityWuxi 214062Jiangsu ProvinceChina

BACKGROUND An increasing number of studies have focused on the role of cellular metabolism in the development of colorectal cancer(CRC).However,no work is currently available to synthesize the field through *** To analyze the development in the field of“glucose metabolism”(GM),“amino acid metabolism”(AM),“lipid metabolism”(LM),and“nucleotide metabolism”(NM)in CRC by *** Articles within the abovementioned areas of GM,AM,LM and NM in CRC,which were published from January 1,1991,to December 31,2022,are retrieved from the Web of Science Core Collection and analyzed by CiteSpace 6.2.R4 and VOSviewer *** The field of LM in CRC presented the largest number of annual publications and the fastest increase in the last decade compared with the other three ***,China and the United States were two of the most prominent contri-butors in these four *** addition,Gang Wang,Wei Jia,Maria Notar-nicola,and Cornelia Ulrich ranked first in publication numbers,while Jing-Yuan Fang,Senji Hirasawa,Wei Jia,and Charles Fuchs were the most cited authors on average in these four fields,respectively.“Gut microbiota”and“epithelial-mesenchymal transition”emerged as the newest burst words in GM,“gut microbiota”was the latest outburst word in AM,“metastasis”,“tumor microenvironment”,“fatty acid metabolism”,and“metabolic reprogramming”were the up-to-date outbreaking words in LM,while“epithelial-mesenchymal transition”and“apoptosis”were the most recently occurring words in *** Research in“cellular metabolism in CRC”is all the rage at the moment,and researchers are particularly interested in exploring the mechanism to explain the metabolic alterations in *** metabolic vulnerability appears to be a promising direction in CRC therapy.

关键词： Cellular metabolism Colorectal cancer Glucose metabolism Amino acid metabolism Lipid metabolism Nucleotide metabolism

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Retrieval of Antarctic sea ice freeboard and thickness from HY-2B satellite altimeter data

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Acta Oceanologica Sinica 2024年第3期43卷 87-101页

作者： Yizhuo Chen Xiaoping Pang Qing Ji Zhongnan yan Zeyu liang Chenlei Zhang Chinese Antarctic Center of Surveying and Mapping Wuhan UniversityWuhan 430079China Key Laboratory of Polar Surveying and Mapping Science Ministry of Natural ResourcesWuhan 430079China Key Laboratory of Polar Environment Monitoring and Public Governance Ministry of EducationWuhan 430079China 4 School of Geography and Tourism Anhui Normal UniversityWuhu 241002China

Antarctic sea ice is an important part of the Earth’s atmospheric system,and satellite remote sensing is an important technology for observing Antarctic sea *** Chinese Haiyang-2B(HY-2B)satellite altimeter data could be used to estimate sea ice freeboard and provide alternative Antarctic sea ice thickness information with a high precision and long time series,as other radar altimetry satellites can,needs further *** paper proposed an algorithm to discriminate leads and then retrieve sea ice freeboard and thickness from HY-2B radar altimeter *** first collected the Moderate-resolution Imaging Spectroradiometer ice surface temperature(IST)product from the National Aeronautics and Space Administration to extract leads from the Antarctic waters and verified their accuracy through Sentinel-1 Synthetic Aperture Radar ***,a surface classification decision tree was generated for HY-2B satellite altimeter measurements of the Antarctic waters to extract leads and calculate local sea surface *** then estimated the Antarctic sea ice freeboard and thickness based on local sea surface heights and the static equilibrium ***,the retrieved HY-2B Antarctic sea ice thickness was compared with the CryoSat-2 sea ice thickness and the Antarctic Sea Ice Processes and Climate(ASPeCt)ship-based observed sea ice *** results indicate that our classification decision tree constructed for HY-2B satellite altimeter measurements was reasonable,and the root mean square error of the obtained sea ice thickness compared to the ship measurements was 0.62 *** proposed sea ice thickness algorithm for the HY-2B radar satellite fills a gap in this application domain for the HY-series satellites and can be a complement to existing Antarctic sea ice thickness products;this algorithm could provide long-time-series and large-scale sea ice thickness data that contribute to research on global climate change.

关键词： HY-2B satellite altimeter classification decision tree sea ice freeboard and thickness Antarctic waters

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Endophthalmitis in silicone oil-filled eye: A case report

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World Journal of Clinical Cases 2024年第1期12卷 163-168页

作者： hui-Chao yan Ze-Lu Wang Wen-Zhen Yu Ming-Wei Zhao Jian-Hong liang Hong Yin Xuan Shi Heng Miao Department of Ophthalmology Peking University People’s HospitalBeijing 100044China

BACKGROUND Endophthalmitis occurring in silicone oil-filled eyes is a very rare occurrence,with reported incidence rates ranging between 0.07%and 0.039%.Traditional methods of management of infectious endophthalmitis include the removal of silicone oil,washout of the vitreous cavity,administration of intravitreal antibiotics,and reinjection of silicone *** SUMMARY Herein,we report the case of a 39-year-old man with unilateral endophthalmitis after pars plana vitrectomy and silicone oil *** injections of full-dose antibiotics and anterior chamber washout were used to treat the *** signs of retinal toxicity were observed during the follow-up *** Intravitreal full-dose antibiotic injections and anterior chamber washout are promising alternatives to traditional therapies for endophthalmitis in silicone oilfilled eyes.

关键词： Endophthalmitis Intravitreal injection Silicone oil-filled eye Pars plana vitrectomy Washout Case report

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The moment map for the variety of associative algebras

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Science China Mathematics 2024年

作者： hui Zhang Zaili yan School of Mathematics Southeast University School of Mathematics and Statistics Ningbo University

We consider the moment map m:PV_n→iu（n） for the action of GL（n） on Vn=?2（C~n）*?C~n,and study the critical points of the functional ■:PVn→***,we prove that[μ]∈PV_n is a critical point if and only if Mμ=cμI+Dμfor some cμ∈R and Dμ∈Der（μ）,where ■.Then we show that any algebraμadmits a Nikolayevsky derivation?μwhich is unique up to automorphism,and if moreover,[μ]is a critical point of Fn,then■ .Secondly,we characterize the maxima and minimatof the functional F_n:A_n→R,where An denotes the projectivization of the algebraic varieties of all the n-dimensional associative ***,for an arbitrary critical point[μ]of F_n:A_n→R,we obtain a description of the algebraic structure ofμ.Finally,we classify the critical points of F_n:A_n→R for n=2and n=3,respectively.

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Multi-area Frequency-constrained Unit Commitment for Power Systems with High Penetration of Renewable Energy Sources and Induction Machine Load

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 754-766页

作者： Leibao Wang hui Fan Jifeng liang Longxun Xu Tiecheng Li Peng Luo Bo Hu Kaigui Xie the State Grid Hebei Electric Power Research Institute Shijiazhuang 050021China State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqing 400044China

The increasing penetration of renewable energy sources(RESs)brings great challenges to the frequency security of power *** traditional frequency-constrained unit commitment(FCUC)analyzes frequency by simplifying the average system frequency and ignoring numerous induction machines(IMs)in load,which may underestimate the risk and increase the operational *** this paper,we consider a multiarea frequency response(MAFR)model to capture the frequency dynamics in the unit scheduling problem,in which regional frequency security and the inertia of IM load are modeled with high-dimension differential algebraic equations.A multi-area FCUC(MFCUC)is formulated as mixed-integer nonlinear programming(MINLP)on the basis of the MAFR ***,we develop a multi-direction decomposition algorithm to solve the MFCUC *** original MINLP is decomposed into a master problem and *** subproblems check the nonlinear frequency dynamics and generate linear optimization cuts for the master problem to improve the frequency security in its optimal *** studies on the modified IEEE 39-bus system and IEEE 118-bus system show a great reduction in operational ***,simulation results verify the ability of the proposed MAFR model to reflect regional frequency security and the available inertia of IMs in unit scheduling.

关键词： Decomposition algorithm frequency response frequency-constrained unit commitment induction machine multi-area mixed-integer nonlinear programming(MINLP)

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A target parameter estimation method via atom-reconstruction in radar mainlobe jamming

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Journal of Systems Engineering and Electronics 2024年第2期35卷 350-360页

作者： ZHOU Bilei LIU Weijian LI Rongfeng CHEN hui ZHANG liang DU Qinglei LI Binbin CHEN Hao Air Force Early Warning Academy Wuhan 430019China Aerospace Nanhu Electronic Information Technology Co. Ltd.Jingzhou 434000China

Mainlobe jamming(MLJ)brings a big challenge for radar target detection,tracking,and *** suppression of MLJ is a hard task and an open problem in the electronic counter-counter measures(ECCM)*** parameters and target direction estimation is difficult in radar MLJ.A target parameter estimation method via atom-reconstruction in radar MLJ is proposed in this *** proposed method can suppress the MLJ and simultaneously provide high estimation accuracy of target range and ***,the eigen-projection matrix processing(EMP)algorithm is adopted to suppress the MLJ,and the target range is estimated effectively through the beamforming and pulse *** the target angle can be effectively estimated by the atom-reconstruction *** any prior knowledge,the MLJ can be canceled,and the angle estimation accuracy is well ***,the proposed method does not have strict requirement for radar array construction,and it can be applied for linear array and planar ***,the proposed method can effectively estimate the target azimuth and elevation simultaneously when the target azimuth(or elevation)equals to the jamming azimuth(or elevation),because the MLJ is suppressed in spatial plane dimension.

关键词： mainlobe jamming anti-jamming atom-reconstruction radar

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Hydrogen storage thermodynamics and kinetics of as-cast Ce-Mg-Ni-based alloy

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Journal of Iron and Steel Research International 2024年第3期31卷 752-766页

作者： yan Qi Xin Zhang Jun Li Dong-liang Zhao Shi-hai Guo yang-huan Zhang Department of Functional Material Research Central Iron and Steel Research InstituteBeijing 100081China China Rare Earth New Material(Weishan)Co..Ltd. Jining 277600ShandongChina Collaborative Innovation Center of Integrated Exploitation of Bayan Obo Multi-Metal Resources Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina

The reaction kinetics of alloys based on magnesium are known to be greatly improved by the partial substitution of Mg with rare earths and transition metals,particularly *** enhanced superficial hydrogen dissociation rate,the weakened Mg-H bond and the lower activation energy following element replacement are thought to be related to the better *** experimental alloys Ce5Mg_(95-x)Ni_(x)(x=5,10,15)were smelted by the vacuum induction *** phase transformation and structural evolution of experimental alloys before and after reaction with hydrogen were char-acterized by X-ray diffraction,scanning electron microscopy and transmission electron *** cast specimens contain CeMg_(12),Mg and Mg_(2)Ni phases,and the increase in Ni content results in an obvious growth of Mg_(2)Ni *** isothermal and non-isothermal hydrogenation and dehydrogenation kinetics of the experimental specimens were investi-gated using the Sievert apparatus,differential scanning calorimetry and thermal gravimetric *** activation energy may be calculated using the Arrhenius and Kissinger *** experimental alloys have been shown to have good activation properties,with a reversible hydriding and dehydriding capacities of around 5.0 wt.%in the first *** initial dehydrogenation temperature of MgH_(2) decreases from 557.5 to 537.7 K with changing Ni content from 5 to 15 at.%.The dehydrogenation activation energy also reduces from 77.09 to 62.96 kJ/mol,which explains the improved hydrogen storage performance caused by Ni *** can be shown that the impact of Ni on the decomposition enthalpy of MgH_(2) is quite modest,with the absolute enthalpy(ΔHr)only decreasing from 78.48 to 76.15 kJ/mol.

关键词： Mg-based alloy Ni content Hydrogen storage kinetics Thermodynamic property Activation energy

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Total ionizing dose effect modeling method for CMOS digital-integrated circuit

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Nuclear Science and Techniques 2024年第2期35卷 32-46页

作者： Bo liang Jin-hui Liu Xiao-Peng Zhang Gang Liu Wen-Dan Tan Xin-Dan Zhang School of Computer Science and Technology Xidian UniversityXi’an 710071China

Simulating the total ionizing dose(TID)of an electrical system using transistor-level models can be difficult and expensive,particularly for digital-integrated circuits(ICs).In this study,a method for modeling TID effects in complementary metaloxide semiconductor(CMOS)digital ICs based on the input/output buffer information specification(IBIS)was *** digital IC was first divided into three parts based on its internal structure:the input buffer,output buffer,and functional *** of these three parts was separately *** the IBIS model,the transistor V-I characteristic curves of the buffers were processed,and the physical parameters were extracted and modeled using *** the functional area,logic functions were modeled in VHDL according to the data sheet.A golden digital IC model was developed by combining the input buffer,output buffer,and functional area ***,the golden ratio was reconstructed based on TID experimental data,enabling the assessment of TID effects on the threshold voltage,carrier mobility,and time series of the digital *** experiments were conducted using a CMOS non-inverting multiplexer,NC7SZ157,and the results were compared with the simulation results,which showed that the relative errors were less than 2%at each dose *** confirms the practicality and accuracy of the proposed modeling *** TID effect model for digital ICs developed using this modeling technique includes both the logical function of the IC and changes in electrical properties and functional degradation impacted by TID,which has potential applications in the design of radiation-hardening tolerance in digital ICs.

关键词： CMOS digital-integrated circuit Total ionizing dose IBIS model Behavior-physical hybrid model Physical parameters

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Experimental Study on Soot Suppression of Acetylene Diffusion Flame by Acoustic-Excited Oscillation in Rijke-Type Burner

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Journal of Thermal Science 2024年第1期33卷 235-248页

作者： ZHU Yibin GUO hui SUO yan'ge WU Minle YE yanghui LI Guoneng ZHANG Zhiguo School of Mechanical and Energy Engineering Zhejiang University of Science and TechnologyHangzhou 310023China

This work reports that the flame oscillation induced by acoustic excitation can effectively suppress soot generation in Rijke-type *** the acoustic frequency is close to the natural frequency of the burner system,it can produce resonance resulting in intense oscillation of the *** relationship between the soot suppression efficiency and the acoustic field of standing wave at different flame positions is *** with that under self-excited oscillation,when there is external forced acoustic force introduced to the flame,oscillation combustion occurred in a lager zone in the glass *** fundamental cause of different soot suppression efficiency at different positions is that the standing wave acoustic field causes the particles to move at different speeds in different positions of the glass *** axial particle velocity difference results in the formation of acoustic vortexes and the change of the flame *** high particle velocity causes the air in the glass tube to turn into the turbulent condition and make the flame temperature *** results show that the surface growth rate of soot is reduced,while the oxidation rate of soot is enhanced,which result in the soot suppression under acoustic *** study can provide some reference for the practical application of oscillate combustion in soot suppression.

关键词： soot suppression acetylene diffusion flame acoustic-excited oscillation standing wave

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A data-driven approach to RUL prediction of tools

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Advances in Manufacturing 2024年第1期12卷 6-18页

作者： Wei Li liang-Chi Zhang Chu-Han Wu yan Wang Zhen-Xiang Cui Chao Niu Department of Mechanical Engineering University College LondonLondonWC1E 7JEUK Shenzhen Key Laboratory of Cross-Scale Manufacturing Mechanics Southern University of Science and TechnologyShenzhen518055GuangdongPeople’s Republic of China SUSTech Institute for Manufacturing Innovation Southern University of Science and TechnologyShenzhen518055GuangdongPeople’s Republic of China Department of Mechanics and Aerospace Engineering Southern University of Science and TechnologyShenzhen518055GuangdongPeople’s Republic of China School of Mechanical and Manufacturing Engineering The University of New South WalesKensingtonNSW2052Australia Baoshan Iron&Steel Co. Ltd.Shanghai200941People’s Republic of China

An effective and reliable prediction of the remaining useful life(RUL)of a tool is important to a metal forming process because it can significantly reduce unexpected maintenance,avoid machine shutdowns and increase system *** study proposes a new data-driven approach to the RUL prediction for metal forming processes under multiple contact sliding *** data-driven approach took advantage of bidirectional long short-term memory(BLSTM)and convolutional neural networks(CNN).A pre-trained lightweight CNN-based network,WearNet,was re-trained to classify the wear states of workpiece surfaces with a high accuracy,then the classification results were passed into a BLSTM-based regression model as inputs for RUL *** experimental results demonstrated that this approach was able to predict the RUL values with a small error(below 5%)and a low root mean square error(RMSE)(around 1.5),which was more superior and robust than the other state-of-the-art methods.

关键词： Remaining useful life(RUL) Bidirectional long short-term memory(BLSTM) Data-driven approach Metal forming

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