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Characteristics of an Indium-Rich InGaN p-n Junction Grown on a Strain-Relaxed InGaN Buffer Layer

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Chinese Physics Letters 2013年第4期30卷 174-176页

作者： YANG lian-Hong ZHANG Bao-Hua guo Fu-Qiang Xinjiang Laboratory of Phase Transitions and Microstructures of Condensed Matter Yili Normal UniversityYining 835000 Department of Physics Changji CollegeChangji 831100

An indium-rich InGaN p-n junction is grown on a strain-relaxed InGaN buffer *** results show that the n-InGaN is grown coherently on the buffer layer but the p-InGaN layer exhibits a partial strain *** fabricated InGaN p-n junction has a low reverse leakage current density on the order of 10^(-8)A/cm^(2)within the measured voltage range,and exhibits a wide spectral response due to the presence of band tail states or deep level states which origin from indium composition fluctuation or various *** measured peak responsivity at 438 nm is 31 mA/W at zero bias and reaches 118 mA/W at 3 V reverse *** addition,the Raman spectra of the p-and n-type InGaN alloys are also analyzed.

关键词： InGaN relaxed indium

Diverse microbiota in palatal radicular groove analyzed by Illumina sequencing:Four case reports

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World Journal of Clinical Cases 2021年第23期9卷 6846-6857页

作者： Xue-lian Tan xuan Chen Yu-Jie Fu Ling Ye Lan Zhang Ding-Ming Huang State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Department of Operative Dentistry and Endodontics West China Hospital of Stomatology Sichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND A palatal radicular groove is an unusual developmental deformity of the tooth,which may serve as a channel linking the periodontal and periapical inflammation,and yet no literature could be obtained analyzing microbiota within the palatal radicular *** SUMMARY Four patients diagnosed with palatal radicular groove and concomitant periodontal-endodontic deformity in permanent maxillary lateral incisors were enrolled in this *** bacterial samples from 4 patients were collected from different parts of the palatal radicular groove during intentional replantation *** sequencing was performed to analyze the taxonomical composition and microbiome structure inside the palatal grooves,and 1162 operational taxonomic units were *** phyla of Firmicutes and Proteobacteria predominated in most of the *** unknown genus from the Bacillaceae family,Lactococcus,and Porphyromonas were the most abundant genera *** was no difference in the microbiota richness and diversity in three sections of the *** The unique ecological niches inside the palatal grooves harbored bacterial communities that shared some component features of both the endodontic and periodontal *** existence of palatal groove may play an interaction bridge between the root apex and tooth cervix and thus impair the outcome of traditional therapeutic methods such as root canal treatment and periodontal management.

关键词： Palatal radicular groove High-throughput sequencing Microbiota composition Taxonomy Endodontic-periodontal infection Case report

Understanding the Electronic Structure and Stability of B_(n)X_(n)^(0/2-)(n=4,6;X=H,F,Cl,Br,I,At,Ts)Clusters

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Chinese Journal of Chemistry 2021年第7期39卷 1811-1818页

作者： Ruo-Ya Wang Jing-xuan Zhang Xue-lian Jiang Nana Ma Xuenian Chen Cong-Qiao Xu Jun Li Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials School of Chemistry and Chemical EngineeringHenan Normal UniversityXinxiangHenan453007 China Department of Chemistry Southern University of Science and TechnologyShenzhenGuangdong518055 China Green Catalysis Center and College of Chemistry Zhengzhou UniversityZhengzhouHenan450001 China Department of Chemistry and Key Laboratory of Organic Optoelectronics&Molecular Engineering of Ministry of Education Tsinghua UniversityBeijing100084 China

Main observation and conclusion Borane clusters and their derivatives have attracted extensive attention in inorganic chemistry due to their fascinating multi-center bonding patterns and physicochemical *** we report ... 详细信息

关键词： Boron Multi-center bonding Electronic structure Chemical bonding Aromaticity

Dairy product consumption and gastric cancer risk: A meta-analysis

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World Journal of Gastroenterology 2014年第42期20卷 15879-15898页

作者： Yan Sun lian-Jie Lin Li-xuan Sang Cong Dai Min Jiang Chang-Qing Zheng Department of Gastroenterology Shengjing Hospital of China Medical University Department of Gastroenterology First Affiliated Hospital of China Medical University

AIM: To investigate whether dairy product consumption is a risk factor for gastric cancer. METHODS: We searched the Pub Med and Web of Science databases for English-language studies on dairy product consumption and gastric cancer risk that were published between October 1980 and September 2013. One author independently extracted data and assessed study quality. Based on the heterogeneity results, we used either the fixed effects model or the random effects model to compute the summary relative risks and 95% confidence intervals(CIs). We also analyzed subgroups according to the study design, geographic region, sex, and whether there were adjustments for confounders(smoking and drinking) with respect to the sources of ***:We found 39 studies that were potentiallyeligible for inclusion in this meta-analysis,including 10cohort studies and 29 case-control *** summary relative risk for gastric cancer,comparing the highest and lowest dairy product consumption categories,was 1.06(95%CI:0.95-1.18).Specific analyses for milk,butter,and margarine yielded similar results,but the results for cheese and yogurt were *** was significant heterogeneity for all studies(Q=112.61;P=0.000;I2=67.1%).No publication bias was observed(Egger’s test:P=0.135;Begg’s test:P=0.365).There was a nonsignificant association between dairy product consumption and gastric cancer risk in the subgroup analysis for the study design,sex,geographic region,and whether there were adjustments for confounders(smoking and drinking).CONCLUSION:In our meta-analysis,dairy product consumption was associated with a nonsignificantly increased risk of gastric ***,this result should be verified using large,well-designed prospective studies.

关键词： Milk Dairy product Gastric cancer Meta-analysis

Gene Expression Profiles of Response to Water Stress at the Jointing Stage in Wheat

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Agricultural Sciences in China 2010年第3期9卷 325-330页

作者： SHI Jun-feng MAO Xin-guo JING Rui-lian PANG Xiao-bin WANG Yu-guo CHANG Xiao-ping The National Key Facility for Crop Gene Resources and Genetic Improvement/Key Laboratory of Crop Germplasm & Biotechnology Ministry of Agriculture/Institute of Crop Sciences Chinese Academy of Agricultural Sciences Beijing 100081 P.R.China Institute of Farm Products Storage Shanxi Academy of Agricultural Sciences Taiyuan 030031 P.R.China Agronomy College Shanxi Agricultural University Taigu 030801 P.R.China

Drought is one of the most adverse environmental factors that impact on plant growth and reduce crop yields. To decipher the molecular mechanism of drought tolerance, we constructed a cDNA library using suppression subtractive hybridization （SSH） and dissected the gene expression profiles in seedling and jointing wheat plants after stress with PEG-6000. A total of 2 046 ESTs from the jointing stage library （J-Lib） were allocated to 961 contigs. Among the ESTs, 265 uni-genes in 12 categories were identified on the basis of sequence similarities and functional classifications. Most were known to be involved in protection, directly or indirectly, against water stress. To determine differences in gene expression profiles for water stress responses at the jointing and seedling stages, data from the J-Lib were compared with those from a 2- leaf seedling library （S-Lib） constructed by the same method. Significant differences were observed between the two libraries for function-known genes; signal transduction genes were far more active at jointing than at the seedling stage.

关键词： wheat suppression subtractive hybridization library EST drought stress

The study on the shrink-fit multi-ring flywheel with fall-off function

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Nuclear Science and Techniques 2017年第3期28卷 115-122页

作者： Yu-Jin Wang De-Zhong Wang Wei-Zhong guo Jun-lian Yin Cheng-Wei Wang School of Mechanical Engineering Shanghai Jiao Tong University Shanghai 200240 China Dalian Clean Energy Heavy Industrial Co. LTDDalian 116630 China

Structural integrity of the flywheel of reactor coolant pump is important for safe operation of a nuclear power plant. A shrink-fit multi-ring flywheel is designed with a fall-off function, i.e., it will separate from the shaft at a designed fall-off rotation speed, which is determined by the assembly process and the gravity. However, the two factors are ignored in the analytical method based on the Lame's equation. In this work, we conducted fall-off experiments to analyze the two factors and used the experimental data to verify the validity of the analytical method and the finite element method(FEM). The results show that FEM performs better than the analytical method in designing the falloff function of the flywheel, though FEM cannot successfully predict the strain variation with the rotational speed.

关键词： Multi-ring flywheel Fall-off rotational speed Shrink-fit assembly Gravity

G protein-coupled receptor kinase 2 inhibition improves erectile function through amelioration of endothelial dysfunction and oxidative stress in a rat model of type 2 diabetes

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Asian Journal of Andrology 2019年第1期21卷 74-79页

作者： Zhi-Hua Wan Yuan-Jie Zhang Lin Chen Yong-lian guo guo-Hao Li Ding Wu Yong Wang Department of Urology The Central Hospital of WuhanTongll Medical CollegeHuazhong University of Science and TechnologyWuhan 430014China

Type 2 diabetes mellitus (T2DM)is a common cause of erectile dysfunction (ED).It has been demonstrated that G protein-coupled receptor kinase 2 (GRK2)overexpression contributes to diabetic endothelial dysfunction and oxidative stress,which also underlies ED in *** hypothesized that GRK2 overexpressed and attenuated endothelial function of the cavernosal tissue in a rat model of T2DM.T2DM rats were established by feeding with a high-fat diet (HFD)for 2 weeks and then administering two intraperitoneal (IP) injections of a low dose of streptozotocin (STZ),followed by continuous feeding with a HFD for 6 ***2 was inhibited by IP injection of paroxetine,a selective GRK2 inhibitor,after STZ *** challenge tests,intracavernous pressure (ICP), GRK2 expression,the protein kinase B (Akt)/endothelial nitric oxide synthase (eNOS)pathway,nicotinamide adenine dinucleotide phosphate (NADPH)oxidase subunit gp91phox,nitric oxide (NO),reactive oxygen species (ROS)production,and apoptosis in cavernosal tissue were *** response to insulin injection was observed in T2DM rats 2 weeks after *** increased GRK2 expression,along with impaired Akt/eNOS pathway,reduced NO production,increased gp91phox expression and ROS generation,increased apoptosis and impaired erectile function were found in T2DM *** of GRK2 with paroxetine ameliorated Akt/eNOS signaling,restored NO production,downregulated NADPH oxidase,subsequently inhibited ROS generation and apoptosis,and ultimately preserved erectile *** results indicated that GRK2 upregulation may be an important mechanism underlying T2DM ED,and GRK2 inhibition may be a potential therapeutic strategy for T2DM ED.

关键词： endothelial dysfunction erectile dysfunction G protein-coupled receptor kinase 2 oxidative stress type 2 diabetes mellitus

Physicochemical characterization of Baizhi particles by ultrafine pulverization

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International Journal of Minerals,Metallurgy and Materials 2011年第2期18卷 247-251页

作者： lian-wei Yang Peng Sun guo-sheng Gai Yu-fen Yang Yu-rong Wang Department of Material Science and Technology Tsinghna University Beijing 100084 China Department of Material Science and Technology Northeastern University at Qinhuangdao Branch Qinlauangdao 066004 China School of Chinese Pharmacy Beijing University of Chinese Medicine Beijing 100029 China

Baizhi, as a medicinal plant, has been demonstrated to be useful for the treatment of aches and pains in China. The physicochemical characterization of Baizhi particles is greatly influenced by ultrafine pulverization. To study the physicochemical characterization of Baizhi, the raw plant material of Baizhi was ground to 6 μm particles by a high speed centrifugal sheering （HSCS） pulverizer. The micron particles were characterized by optical microscopy and scanning electron microscopy （SEM）. Imperatorin is one of the active ingredients of Baizhi, and its extraction yield is determined to evaluate the chemical characterization of Baizhi powder. Imperatorin was analyzed by high performance liquid chromatography （HPLC）. The results show that after ultrafine pulverization, the plant cell walls are broken into pieces and the extraction yield of imperatorin is increased by 11.93% compared with the normal particles.

关键词： Baizhi physicochemical characterization pulverization imperatorin extraction

Effects of selective cyclooxygenase-2 inhibitor on C6 glioma cell proliferation and apoptosis

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Neural Regeneration Research 2009年第11期4卷 923-927页

作者： Shiwen guo Tao Li Hongmin Che Wenzhi Li Minxue lian Yuliang Han Department of Neurosurgery First Affiliated Hospital Medical School Xi'an Jiaotong University Xi'an 710061 Shaanxi Province China

BACKGROUND： Studies have shown that cyclooxygenase-2 is associated with proliferation and apoptosis of glioma cells. OBJECTIVE： To investigate the effects of selective cyclooxygenase-2 inhibitor celecoxib on proliferation and apoptosis of C6 glioma cells in vitro. DESIGN, TIME AND SETTING： A cellular, molecular, controlled study was performed at the Central Laboratory and Room of Electron Microscope, Medical School, Xi＇an Jiaotong University, China from March 2007 to March 2008. MATERIALS： C6 glioma cells during in vitro log phase were assigned to control and experimental groups. Celecoxib （Pfizer, USA）, dimethyl sulfoxide （Sigma, USA）, and MTT （Sigma, USA） were used for this study. METHODS： The control group was subdivided into blank control and dimethyl sulfoxide control groups. C6 glioma cells in the blank control and dimethyl sulfoxide control groups were incubated in Dulbecco＇s modified Eagle＇s medium supplemented with 10% calf serum and 0.3% dimethyl sulfoxide respectively. C6 glioma cells in the experimental group were separately treated with 60, 80 and 100 μmol/L celecoxib. MAIN OUTCOME MEASURES： Activity of C6 glioma cells was examined by MTT assay. C6 glioma cell cycle and apoptosis were determined by annexin V-fluorescein isothiocyanate/propidium iodide double-staining, followed by flow cytometry. Morphology and ultrastructure of C6 glioma cells were observed with an inverted microscope and a transmission electron microscope, respectively. RESULTS： Compared with the blank control group, cell density was reduced, adherence ability weakened, and irregular nuclei were visible, with the presence of chromatin condensation, margination, and some apoptotic bodies in the experimental group. Activity of C6 glioma cells was significantly decreased （P 〈 0.05）, cell number was reduced during S phase, cell number was significantly increased during G2/M phase （P 〈 0.01 ）, and the apoptotic rate was significantly increased （P 〈 0.05） in the experimental group. These res

关键词： celecoxib C6 glioma cells proliferation apoptosis