检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

精神分裂症患者发生糖尿病的危险因素分析

中国行为医学科学 2006年第11期15卷 1010-1011页

作者：梁雪梅刘可智四川大学临床医学院华西医院精神科成都610041

目的探讨精神分裂症患者发生糖尿病(DM)的可评估性危险因素。方法自制调查表,对精神分裂症患者发生DM的可能影响因素中可以评估的因素进行回顾性调查及统计学分析。结果336例精神分裂症患者中,3年间发生DM22例(6.5%),Logistic回归分析... 详细信息

目的探讨精神分裂症患者发生糖尿病(DM)的可评估性危险因素。方法自制调查表,对精神分裂症患者发生DM的可能影响因素中可以评估的因素进行回顾性调查及统计学分析。结果336例精神分裂症患者中,3年间发生DM22例(6.5%),Logistic回归分析显示其发病的危险因素包括有DM家族史、肥胖、病程长、平日血糖偏高、接受氯氮平治疗等。结论精神分裂症患者发生DM的危险因素高,可以进行预测性评估和提早干预。

关键词：精神分裂症糖尿病发生率危险因素

麦芽糊精硬脂酸酯的酶法合成及其乳化性的研究

在线全文

学校读者我要写书评

暂无评论

食品与生物技术学报 2013年第1期32卷 9-14页

作者：孙平杨惠娟王雅琦刘可志徐雅雯食品营养与安全教育部重点实验室天津科技大学天津300457

研究了麦芽糊精硬脂酸酯的酶法合成工艺及其性能,对该工艺的影响因素进行单因素及正交试验。所确定的较佳工艺条件为:硬脂酸与糊精质量比为4∶1,酶添加量为7 g/L,反应温度65℃,反应时间60 h,并研究了其结构与乳化性能。结果表明:乳液的... 详细信息

研究了麦芽糊精硬脂酸酯的酶法合成工艺及其性能,对该工艺的影响因素进行单因素及正交试验。所确定的较佳工艺条件为:硬脂酸与糊精质量比为4∶1,酶添加量为7 g/L,反应温度65℃,反应时间60 h,并研究了其结构与乳化性能。结果表明:乳液的乳化性随糖酯的质量分数增加而增加。在相同质量分数下,麦芽糊精硬脂酸酯乳化性最好,高于麦芽糖脂肪酸酯以及淀粉脂肪酸酯。

关键词：麦芽糊精硬脂酸乳化性

在线全文

学校读者我要写书评

暂无评论

提高伺服系统快速性的探讨

清华大学学报(自然科学版) 1980年第1期 99-109页

作者：刘植桢何克忠计算机工程与科学系

本文着重讨论建造快速伺服系统工程实践中的问题。其主要之点有：１．必须研制小惯性电子线路以取代惯性较大的平滑滤波电路及功率部件等。２．采用测速反馈改善伺服电机性能的关键在于设计理想的功率部件和避免机组的弹性联接。３... 详细信息

本文着重讨论建造快速伺服系统工程实践中的问题。其主要之点有：１．必须研制小惯性电子线路以取代惯性较大的平滑滤波电路及功率部件等。２．采用测速反馈改善伺服电机性能的关键在于设计理想的功率部件和避免机组的弹性联接。３．采用机械与电子线路相结合的方法，可以有效地的增加动力传递机构的阻尼。４．利用本文介绍的分析方法进行动态设计，可使系统接近最优快速系统的指标。方法简便，比之一般的综合方法易为工程技术人员掌握。５．讨论小参数对反馈系统的影响时，需要注意弱阻尼二阶环节的作用，用低通滤波进行校正将会影响系统的快速性。

关键词：伺服系统性能指标调节时间跟随控制系统微分时间常数快速性速航性

Bifunctional bridging capping layer enables 24.5% efficiency of perovskite solar cells with polymer-based hole transport materials

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第1期 350-359页

作者： Can Zhu Yiyang Wang Lei Meng Beibei Qiu Jing Li Shucheng Qin ke Hu Xin Jiang Wenbin Lai Minchao liu Zhe liu Chenxing Lu Jinyuan Zhang Yongfang Li Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences School of Chemical Science University of Chinese Academy of Sciences key Laboratory of Solid State Optoelectronic Devices of Zhejiang Province College of Physics and Electronic Information Engineering Zhejiang Normal University key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of Sciences Laboratory of Advanced Optoelectronic Materials College of Chemistry Chemical Engineering and Materials ScienceSoochow University

Developing a bridge capping layer between perovskite and hole transport layer materials（HTMs） in the n-i-p perovskite solar cells（pero-SCs） is an effective approach to modify the morphology of HTMs and passivate the perovskite ***, we select the quinoxaline-based bifunctional passivation agent, quinoxalin-6-yl-methylamine hydrochloride（Qx MACl）,as the bridging layer, and a D-A copolymer PBQ12 containing the same quinoxaline unit as an HTM for the n-i-p pero-SCs. Due to the π-π stacking among the common quinoxaline units in the bridge layer and HTM, Qx MACl induces the π-π stacking of the PBQ12 film and improves the film morphology of HTMs with better conductivity. Additionally, Qx MACl can effectively passivate the perovskite surface, and PBQ12 possesses appropriate energy levels and high hole mobility. The pero-SCs based on FAPbI3with PBQ12/Qx MACl treatment showed a higher power conversion efficiency（PCE） of 24.05% and outstanding stability, maintaining 95.4% and 92.1% of its initial PCE after 750 h of storage and after over 800 h of thermal annealing at 85 °C, respectively. To further enhance the PCE of the PBQ12/Qx MACl-based devices, we developed a non-metal ion dopant for the PBQ12 HTM. Through trace doping of PBQ12 HTM by the non-metal ion dopant, the PCE of the PBQ12/Qx MACl-based devices reached 25.24%（the calibrated PCE of 24.55% by the National Institute of Metrology, China）.

关键词：

同方期刊数据库

Co-oxidation of arsenic(Ⅲ) and iron(Ⅱ) ions by pressurized oxygen in acidic solutions

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2020年第2期27卷 181-189页

作者： ke-zhou Song Ping-chao ke zhi-yong liu zhi-hong liu School of Metallurgy and Environment Central South University

The co-oxidation of As(Ⅲ) and Fe(Ⅱ) in acidic solutions by pressured oxygen was studied under an oxygen pressure between 0.5 and 2.0 MPa at a temperature of 150℃. It was confirmed that without Fe(Ⅱ) ions, As(Ⅲ) ions in the solutions are virtually non-oxidizable by pressured oxygen even at a temperature as high as 200℃ and an oxygen pressure up to 2.0 MPa. Fe(Ⅱ) ions in the solutions did have a catalysis effect on the oxidation of As(Ⅲ), possibly attributable to the production of such strong oxidants as hydroxyl free radicals (OH ) and Fe(Ⅳ) in the oxidation process of Fe(Ⅱ). The effects of such factors as the initial molar ratio of Fe(Ⅱ)/As(Ⅲ), initial pH value of the solution, oxygen pressure, and the addition of radical scavengers on the oxidation efficiencies of As(Ⅲ) and Fe(Ⅱ) were studied. It was found that the oxidation of As(Ⅲ) was limited in the co-oxidation process due to the accumulation of the As(Ⅲ) oxidation product, As(Ⅴ), in the solutions.

关键词： co-oxidation As As(Ⅲ)oxidation Fe(Ⅱ) pressured oxygen radical scavenger

2011—2020年宁波市鄞州区炎症性肠病发病的流行病学研究

在线全文

学校读者我要写书评

暂无评论

北京大学学报（医学版） 2022年第3期54卷 511-519页

作者：贺冰洁刘志科沈鹏孙烨祥陈彬詹思延林鸿波北京大学公共卫生学院流行病与卫生统计学系北京100191 鄞州区疾病预防控制中心浙江宁波315199 宁波市肛肠医院浙江宁波315048 北京大学人工智能研究院北京100191

目的:描述宁波市鄞州区常住居民炎症性肠病发病的分布特征,了解该地区炎症性肠病的疾病负担和发展趋势。方法:采用回顾性队列设计,收集2010—2020年鄞州区全民健康信息平台的居民健康档案中所有常住居民的登记信息,利用电子病历随访其... 详细信息

目的:描述宁波市鄞州区常住居民炎症性肠病发病的分布特征,了解该地区炎症性肠病的疾病负担和发展趋势。方法:采用回顾性队列设计,收集2010—2020年鄞州区全民健康信息平台的居民健康档案中所有常住居民的登记信息,利用电子病历随访其炎症性肠病就诊情况,设置1年洗脱期,以登记1年后首次诊断且以炎症性肠病为首要诊断的患者为新发病例。采用泊松分布估算炎症性肠病的发病密度及其95%置信区间(confidence interval,CI)。结果:2011—2020年累计纳入鄞州区常住居民1496427人,其中男性729996人(48.78%),总随访人年8081030.82,中位随访人年5.41[四分位距(interquartile range,IQR):5.29]。研究期间共有1217例炎症性肠病新发病例,男性(624例,51.27%)多于女性(593例,48.73%),总发病密度为15.06/10万人年(95%CI:14.23,15.93),其中溃疡性结肠炎1106例(90.88%),发病密度为13.69/10万人年(95%CI:12.89,14.52);克罗恩病70例(5.75%),发病密度为0.87/10万人年(95%CI:0.68,1.09);未定型结肠炎41例(3.37%),发病密度为0.51/10万人年(95%CI:0.36,0.69)。溃疡性结肠炎的中位发病年龄为50.82岁(IQR:18.77),发病年龄在45~49岁组占比最高(15.01%);发病密度随年龄增长逐渐上升,45~49岁年龄组达到较高水平,随后略有上升,65~69岁年龄组发病密度最高,为25.44/10万人年(95%CI:20.85,30.75),至75~79岁组发病密度迅速下降;克罗恩病的中位发病年龄为44.34岁(IQR:33.41),发病年龄在25~29岁组占比最高(12.86%),由于克罗恩病新发病例数较少,年龄分布波动较大,青年和老年各有峰值。2011—2020年间,鄞州区炎症性肠病的发病密度在2011—2013年处于较低水平,2014—2016年呈迅速上升趋势,2016年达到峰值[24.62/10万人年(95%CI:21.31,28.30)],2017—2020年略有下降。结论:2011—2020年鄞州区炎症性肠病发病密度呈较高水平,医疗机构和卫生部门需重视其所带来的疾病负担。

关键词：炎症性肠病溃疡性结肠炎克罗恩病发病密度队列

同方期刊数据库博看期刊

The compound(E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3330-3344页

作者： Xueyan liu Wei Wu Xuejuan Li Chengyan Wang ke Chai Fanru Yuan Huijuan Zheng Yuxing Yao Chenlu Li Zu-Cheng Ye Daijun Zha Department of Medicinal Chemistry School of PharmacyFujian Medical UniversityFuzhouFujian ProvinceChina Fujian Provincial key Laboratory of Brain Aging and Neurodegenerative Diseases School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Institute of Laboratory Animal Center Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina Department of Hyperbaric Oxygen National Regional Medical CenterBinhai Campus of the First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina

Previous studies have shown that the compound(E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one(D30),a pyromeconic acid derivative,possesses antioxidant and anti-inflammatory properties,inhibits amyloid-β aggregation,and alleviates scopolamine-induced cognitive impairment,similar to the phase Ⅲ clinical drug *** this study,we established a mouse model of Alzheimer's disease via intracerebroventricular injection of fibrillar amyloid-β to investigate the effect of D30 on fibrillar amyloid-β-induced *** results showed that D30 alleviated fibrillar amyloid-β-induced cognitive impairment,promoted fibrillar amyloid-β clearance from the hippocampus and cortex,suppressed oxidative stress,and inhibited activation of microglia and astrocytes.D30 also reversed the fibrillar amyloid-β-induced loss of dendritic spines and synaptic protein ***,we demonstrated that exogenous fibrillar amyloid-βintroduced by intracerebroventricular injection greatly increased galectin-3 expression levels in the brain,and this increase was blocked by *** the role of D30 in clearing amyloid-β,inhibiting neuroinflammation,protecting synapses,and improving cognition,this study highlights the potential of galectin-3 as a promising treatment target for patients with Alzheimer's disease.

关键词： Alzheimer's disease amyloid-β astrocyte cognitive impairment D30 dendritic spines galectin-3 microglia neuroinflammation neuron