检索结果-南通市图书馆

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

TiCp/Fe复合材料制备及组织分析

铸造技术 2006年第3期27卷 243-245页

作者：苏广才刘志科任素波汪振华广西大学机械工程学院广西南宁530004

借助X射线衍射(XRD)、光学金相显微镜以及扫描电镜(SEM),研究了反应铸造工艺制备的原位TiCp/Fe复合材料中增强颗粒的分布和形貌,并通过能谱仪确定了材料微区合金相对成分。结果表明:原位TiC增强颗粒均匀分布在基体中,呈四边形或多边形... 详细信息

借助X射线衍射(XRD)、光学金相显微镜以及扫描电镜(SEM),研究了反应铸造工艺制备的原位TiCp/Fe复合材料中增强颗粒的分布和形貌,并通过能谱仪确定了材料微区合金相对成分。结果表明:原位TiC增强颗粒均匀分布在基体中,呈四边形或多边形。Ti元素主要分布在增强颗粒中,并有一部分固溶于基体。由于Ti元素的烧损,生成了有害相石墨。

关键词： TiCp/Fe复合材料原位反应有害相

The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi Li Jing Xue Yuejia Ma ke Ye Xue Zhao Fangliang Ge Feifei Zheng Lulu liu Xu Gao Dayong Wang Qing Xia Department of Biochemistry and Molecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic Medical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic Medical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina key Laboratory of Heilongjiang Province for Genetically Modified Animals Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational Medicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be a

关键词： Alzheimer's disease cell self-renewal central nervous system memory microglia nerve regeneration neurodegenerative diseases neurogenesis RNA methylation

Record-breaking bifunctional oxygen electrocatalyst accomplished by a data-driven approach for zinc-air batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 144-145页

作者： Deviprasath Chinnadurai zhi Wei Seh Institute of Materials Research and Engineering (IMRE) Agency for Science Technology and Research (A*STAR)

Rechargeable zinc-air batteries(ZABs) have recently drawn great attention in energy research due to their high theoretical capacity,low costs, and inherently safe nature [1–3]. However, the sluggish cathode reactions necessitate the development of bifunctional oxygen electrocatalysts with lower ΔE indicator values. The ΔE indicator is commonly employed to quantitatively evaluate the electrocatalytic activity of a bifunctional oxygen electrocatalyst,representing the overall overpotential from oxygen reduction reaction(ORR) to oxygen evolution reaction(OER).

关键词：

Physical Layer Security Scheme With AoI-Awareness for Industrial IoT Based on Covert Communications

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2025年第1期 276-278页

作者： Yaping Li zhi-Xin liu Jia-Wei Su Ya-Zhou Yuan the key Laboratory of Industrial Computer Control Engineering of Hebei Province Yanshan University

Dear Editor,Industrial Internet of things(IIoT) is a typical application of cyberphysical system(CPS). In the IIoT, wireless communication is an inevitable trend to replace the deployment-limited wired transmission for cases with large-scale and mobile devices. However, wireless communication gives rise to critical issues related to physical security, such as malicious detections and attacks [1].

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

灰铸铁贝氏体等温淬火研究

热加工工艺 2006年第2期35卷 40-41页

作者：汪振华尹志新刘志科尹秉升广西大学机械工程学院广西南宁530004

研究了等温淬火热处理工艺对灰铸铁组织和性能的影响,并确定了860℃保温2h,然后在300℃保温1.5h的等温淬火工艺,在此工艺条件下可获得贝氏体基体的高性能灰铸铁。

关键词：等温淬火灰铸铁贝氏体

双系统加密技术下带通配符的基于身份加密方案

在线全文

学校读者我要写书评

暂无评论

计算机应用研究 2012年第5期29卷 1910-1913,1917页

作者：张晓敏赵永斌刘克智石家庄铁道大学信息与技术学院石家庄050043 渤海石油职业学院河北沧州062552

带通配符的基于身份加密方案(WIBE)大多存在以下缺陷:a)仅达到选择身份(selective-ID)安全,安全系数较低;b)其私钥或密文长度随身份级数呈线性递增,需要耗费大量的存储空间。针对上述问题,运用Waters的双系统加密技术,在Lewko-HIBE方案... 详细信息

带通配符的基于身份加密方案(WIBE)大多存在以下缺陷:a)仅达到选择身份(selective-ID)安全,安全系数较低;b)其私钥或密文长度随身份级数呈线性递增,需要耗费大量的存储空间。针对上述问题,运用Waters的双系统加密技术,在Lewko-HIBE方案的基础上提出了一个密文长度固定的带通配符的分级加密方案。新方案结构紧凑,密钥和密文长度均为常数,加/解密运算速度快,减小了存储空间并提高了计算效率。新方案在标准模型下是适应性选择身份(adaptive-ID)安全的,也叫完全安全,安全级别较选择身份安全更高,并且其安全性可归约为三个静态假设。

关键词：带通配符的基于身份加密双系统加密混合阶群适应性选择身份安全

3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 18-45页

作者： ke Yao Gaoying Hong Ximin Yuan Weicheng Kong Pengcheng Xia Yuanrong Li Yuewei Chen Nian liu Jing He Jue Shi Zihe Hu Yanyan Zhou zhijian Xie Yong He State key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China Liangzhu Laboratory Zhejiang UniversityHangzhou 310027People’s Republic of China key Laboratory of 3D Printing Process and Equipment of Zhejiang Province College of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China Stomatology Hospital School of StomatologyZhejiang University School of MedicineHangzhou 310027People’s Republic of China State key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001People’s Republic of China Institute of Digital Medicine Nanjing First HospitalNanjing Medical UniversityNanjing 210006People’s Republic of China

Hydrogel scaffolds have numerous potential applications in the tissue engineering ***,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical *** by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this ***,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent ***,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell ***,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT *** experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries.

关键词： 3D printing Tough hydrogel scaffold Functional surface structure Tissue regeneration Biomaterials

围产期暴露任基酚对子代大鼠脂肪组织形成影响

在线全文

学校读者我要写书评

暂无评论

中国公共卫生 2018年第2期34卷 249-254页

作者：张宏宇刘志国柯晓煜武汉轻工大学生物制药与工程学院湖北武汉430023 华中科技大学同济医学院附属同济医院

目的探讨围产期暴露壬基酚对子代大鼠脂肪组织的形成以及对大鼠脂肪组织中ERα表达的影响。方法雌性大鼠从妊娠期(GD)第6 d至分娩后21 d分别给予壬基酚(5、25、125μg/kg),另设一对照组,每天灌胃1次。子代出生后(PND)21 d时,处死部分幼... 详细信息

目的探讨围产期暴露壬基酚对子代大鼠脂肪组织的形成以及对大鼠脂肪组织中ERα表达的影响。方法雌性大鼠从妊娠期(GD)第6 d至分娩后21 d分别给予壬基酚(5、25、125μg/kg),另设一对照组,每天灌胃1次。子代出生后(PND)21 d时,处死部分幼鼠,收集血清;剩余部分幼鼠按性别分笼喂养,给予普通饲料至实验结束。23周后,断头处死,收集血液,并迅速取出肾周和性腺周围脂肪组织。结果与对照组[雄性(384±43)g、雌性(231±8)g]比较,5、25、125μg/kg壬基酚组子代大鼠体重[雄性分别为(453±51)、(475±57)、(509±29)g,雌性分别为(260±13)、(260±12)、(284±3)g]均升高(均P<0.05);与对照组比较,各计量壬基酚组子代大鼠血清中瘦素的水平均升高(均P<0.05);与对照组[雄性(6 307±312)μm2、雌性(5 915±287)μm2]比较,5、25、125μg/kg壬基酚组子代大鼠脂肪细胞面积[雄性分别为(10 142±9 209)、(17 465±9 830)、(33 854±2 620)μm2,雌性分别为(10 100±9 095)、(15 134±965)、(31 280±4 654)μm2]均增加(均P<0.05);与对照组比较,各剂量任基酚组子代大鼠脂肪分化和增殖基因表达均增加,子代大鼠脂肪组织中ERα基因和蛋白表达水平均降低(均P<0.05)。结论围产期暴露壬基酚可以导致子代大鼠肥胖,脂肪组织中ERα基因和蛋白表达的降低可能是壬基酚的作用机制之一。

关键词：任基酚脂肪形成子代大鼠

在线全文

学校读者我要写书评

暂无评论

美国营运资产会计政策的分析

武汉冶金管理干部学院学报 2006年第4期16卷 47-48,71页

作者：刘克自蒋慧民湖北大学商学院湖北武汉430062

随着我国会计准则的修订和出台,对微观经济主体的会计行为进行规范的会计政策的制定是当前急需解决的问题,本文通过对美国营运资产会计政策的主要内容进行分析,以期对我国营运资产的管理和政策提供一些借鉴。

关键词：会计政策营运资产财政政策