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山东大学学报（理学版） 2015年第4期50卷 49-55页

作者：刘勇刘希强聊城大学数学科学学院山东聊城252059

利用经典李群法得到了(2+1)维Caudrey-Dodd-Gibbon(简称CDG)方程的对称、约化,并通过解约化方程得到了该方程的一些精确解,其中包括有理函数解,双曲函数解,三角函数解,Jacobi椭圆函数解。

关键词：李群方法 (2+1)维CDG方程精确解对称约化

(2+1)维Boiti-Leon-Manna-Pempinelli方程的对称、精确解及守恒律

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量子电子学报 2008年第5期25卷 546-552页

作者：刘娜刘希强聊城大学数学科学学院山东聊城252059

利用李群分析方法,得到了(2+1)维Boiti-Leon-Manna-Pempinelli(BLMP)方程的对称、相似约化和新的精确解,包括有理函数解、双曲函数解、雅克比椭圆函数解和三角周期解。同时找到了此方程的无穷多守恒律。

关键词：非线性方程 (2+1).维BLMP方程李群分析方法对称精确解守恒律

Recent Development of Heat Transfer and Fluid Flow of Supercritical CO2 in Tubes:Mechanisms and Applications

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Journal of Thermal Science 2024年第06期33卷 2274-2298页

作者： ZHANG xirui SHAO Qihan liu Jian xi Wenxiong liu Chaoyang SUNDEN Bengt Research Institute of Aerospace Technology Central South University College of Aerospace Science and Engineering National University of Defense Technology Department of Energy Sciences Lund University

With the advantages of low cost,excellent ability of heat and mass transfer and easy accessibility to the supercritical point,supercritical CO2has been applied in many engineering devices *** of the sharply-varying thermophysical properties near the supercritical point,heat transfer and flow behavior of supercritical CO2in tubes become complex and have received a lot of research *** main purpose of this paper is to summarize the findings of the published works related to flow phenomena and heat transfer characteristics of supercritical ***,influence parameters related to boundary conditions of supercritical CO2flowing in a smooth tube are ***,commonly-used turbulence and mathematic models dealing with internal flows of supercritical CO2are ***,research works on geometric effects of design parameters,shapes and configurations are *** practical applications of supercritical CO2in recent years are ***,developments and future challenges of supercritical CO2in tubes are analyzed and *** paper provides basic knowledge of heat transfer and fluid flow mechanisms and related practical applications of supercritical CO2in tubes.

关键词： developments and challenges flow behavior heat transfer practical applications supercritical CO2

Artificial intelligence-based pathological analysis of liver cancer:Current advancements and interpretative strategies

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iLIVER 2024年第1期3卷 82-89页

作者： Guang-Yu Ding Jie-Yi Shi xiao-Dong Wang Bo Yan xi-Yang liu qiang Gao Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalShanghai 200032China Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education Fudan UniversityShanghai 200032China School of Computer Science and Technology Xidian UniversityXi'an 710126China School of Computer Science Shanghai Key Laboratory of Intelligent Information ProcessingFudan UniversityShanghai 200433China Institute of Biomedical Sciences Fudan UniversityShanghai 200030China State Key Laboratory of Genetic Engineering Fudan UniversityShanghai 200433China

In recent years,significant advances have been achieved in liver cancer management with the development of artificial intelligence(AI).AI-based pathological analysis can extract crucial information from whole slide images to assist clinicians in all aspects from diagnosis to prognosis and molecular ***,AI techniques have a“black box”nature,which means that interpretability is of utmost importance because it is key to ensuring the reliability of the methods and building trust among clinicians for actual clinical *** this paper,we provide an overview of current technical advancements in the AI-based pathological analysis of liver cancer,and delve into the strategies used in recent studies to unravel the“black box”of AI's decision-making process.

关键词： Liver cancer Artificial intelligence Pathology Interpretative model

Long noncoding RNAs HAND2-AS1 ultrasound microbubbles suppress hepatocellular carcinoma progression by regulating the miR-873-5p/tissue inhibitor of matrix metalloproteinase-2 axis

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1547-1563页

作者： qiang Zou Hao-Wen Wang xi-Liang Di Yuan Li Hui Gao Department of Interventional Therapy Tianjin Medical University Cancer Institute and HospitalTianjin 300060China National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and TherapyTianjin’s Clinical Research Center for CancerTianjin 300060China College of Animal Science and Technology Northeast Agricultural UniversityHarbin 150030Heilongjiang ProvinceChina Department of Hematology and Oncology Linyi People’s HospitalLinyi 251500Shandong ProvinceChina Department of Comprehensive Oncology Baotou Cancer HospitalBaotou 014030Inner Mongolia Autonomous RegionChina

BACKGROUND Increasing data indicated that long noncoding RNAs(lncRNAs)were directly or indirectly involved in the occurrence and development of tumors,including hepatocellular carcinoma(HCC).Recent studies had found that the expression of lncRNA HAND2-AS1 was downregulated in HCC tissues,but its role in HCC progression is *** targeted microbubble destruction mediated gene transfection is a new method to overexpress *** To study the role of ultrasound microbubbles(UTMBs)mediated HAND2-AS1 in the progression of HCC,in order to provide a new reference for the treatment of *** In vitro,we transfected HAND2-AS1 siRNA into HepG2 cells by UTMBs,and detected cell proliferation,apoptosis,invasion and epithelial-mesenchymal transition(EMT)by cell counting kit-8 assay,flow cytometry,Transwell invasion assay and Western blotting,*** addition,we transfected miR-837-5p mimic into UTMBs treated cells and observed the changes of cell ***,the UTMBs treated HepG2 cells were transfected together with miR-837-5p mimic and tissue inhibitor of matrix metalloproteinase-2(TIMP2)overexpression vector,and we detected cell proliferation,apoptosis,invasion and *** vivo,we established a mouse model of subcutaneous transplantation of HepG2 cells and observed the effect of HAND2-AS1 silencing on tumor formation *** We found that UTMBs carrying HAND2-AS1 restricted cell proliferation,invasion,and EMT,encouraged apoptosis,and HAND2-AS1 silencing eliminated the effect of ***,miR-873-5p targets the gene HAND2-AS1,which also targets the 3’UTR of *** miR-873-5p mimic counteracted the impact of ***,miR-873-5p mimic solely or in combination with pcDNA-TIMP2 had been transformed into HepG2 cells exposed to *** discovered that TIMP2 reversed the effect of miR-873-5p mimic caused by the blocked signalling cascade for matrix metalloproteinase(MMP)2/*** vivo results showed that HAND2-AS1 silencing sig

关键词： Hepatocellular carcinoma Ultrasound microbubbles Long noncoding RNA HAND2-AS1 miR-873-5p Tissue inhibitor of matrix metalloproteinase-2

非均匀弹簧界面模型下柱形夹杂物对弹性波的散射

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工程力学 2008年第2期25卷 83-87页

作者：刘希强魏培君北京科技大学应用科学学院数力系北京100083

利用波函数展开法研究了非均匀弹簧界面模型(弹簧系数沿周向非均匀分布)下单个柱形夹杂物对弹性波的散射问题。在弹簧界面模型中,当弹簧系数沿周向分布均匀时,可利用波函数的正交性简化边界条件;当弹簧系数沿周向分布不均匀时,不能利用... 详细信息

利用波函数展开法研究了非均匀弹簧界面模型(弹簧系数沿周向非均匀分布)下单个柱形夹杂物对弹性波的散射问题。在弹簧界面模型中,当弹簧系数沿周向分布均匀时,可利用波函数的正交性简化边界条件;当弹簧系数沿周向分布不均匀时,不能利用波函数的正交性简化边界条件。该文研究了这一问题,通过沿周向的离散化将弹性波散射的边界条件归结为一个超定线性代数方程组。针对Ge-Al纤维增强复合材料数值计算了散射截面和远场散射幅。特别地,通过适当选取弹簧常数的周向分布处理了含裂纹界面的弹性波散射问题,数值计算了裂纹张开位移和错开位移。

关键词：弹簧模型弹性波散射界面裂纹散射截面远场散射幅

Regulating solid electrolyte interphase film on fluorinedoped hard carbon anode for sodium-ion battery

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Carbon Energy 2024年第6期6卷 200-215页

作者： Cuiyun Yang Wentao Zhong Yuqiao liu qiang Deng Qian Cheng xiaozhao liu Chenghao Yang Guangzhou Key Laboratory for Surface Chemistry of Energy Materials New Energy Research InstituteSchool of Environment and EnergySouth China University of TechnologyGuangzhouChina

For the performance optimization strategies of hard carbon,heteroatom doping is an effective way to enhance the intrinsic transfer properties of sodium ions and electrons for accelerating the reaction ***,the previous work focuses mainly on the intrinsic physicochemical property changes of the material,but little attention has been paid to the resulting interfacial regulation of the electrode surface,namely the formation of solid electrolyte interphase(SEI)*** this work,element F,which has the highest electronegativity,was chosen as the doping source to,more effectively,tune the electronic structure of the hard *** effect of F-doping on the physicochemical properties of hard carbon was not only systematically analyzed but also investigated with spectroscopy,optics,and in situ characterization techniques to further verify that appropriate F-doping plays a positive role in constructing a homogenous and inorganic-rich SEI *** experimentally demonstrated link between the electronic structure of the electrode and the SEI film properties can reframe the doping optimization strategy as well as provide a new idea for the design of electrode materials with low reduction kinetics to the *** a result,the optimized sample with the appropriate F-doping content exhibits the best electrochemical performance with high capacity(434.53 mA h g^(-1)at 20mA g^(-1))and excellent rate capability(141 mAh g^(-1)at 400 mA g^(-1)).

关键词： F-doping hard carbon reduction kinetics sodium-ion batteries solid electrolyte interphase film

Experimental Study of Local Scour Around Four Piles Under Different Attack Angles and Gap Ratios

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China Ocean Engineering 2024年第4期38卷 612-624页

作者： liu Ming-ming TANG Guo-qiang JIN xin GENG Shao-yang School of Architecture and Engineering Liaocheng UniversityLiaocheng 252000China Water-Sediment Regulation and Sand Effective Utilization Special Laboratory of Shandong Provincial Education Department Liaocheng UniversityLiaocheng 252000China State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China College of Electronic Engineering Chengdu University of Information TechnologyChengdu 610225China College of Energy Chengdu University of TechnologyChengdu 610059China

In an effort to investigate and quantify the patterns of local scour,researchers embarked on an in-depth study using a systematic experimental *** research focused on the effects of local scour around a set of four piles,each subjected to different hydromechanical *** particular,this study aimed to determine how different attack angles—the angles at which the water flow impinges on the piles,and gap ratios—the ratios of the spacing between the piles to their diameters,influence the extent and nature of scour.A comprehensive series of 35 carefully designed experiments were orchestrated,each designed to dissect the nuances in how the gap ratio and attack angle might contribute to changes in the local scour observed at the base of pile *** these experimental trials,a wealth of local scour data were collected to support the *** data included precise topographic profiles of the sediment bed around the pile groups,as well as detailed scour time histories showing the evolution of scour at strategic feature points throughout the test *** analysis of the experimental data provided interesting *** study revealed that the interplay between the gap ratio and the attack angle had a pronounced influence on the scouring dynamics of the pile *** of the key observations was that the initial phases of scour,particularly within the first hour of water flow exposure,were characterized by a sharp increase in the scour depth occurring immediately in front of the *** this initial rapid development,the scour depth transitioned to a more gradual change *** contrast,the scour topography around the piles continuously *** suggests that sediment displacement and the associated sculpting of the seabed around pile foundations are sustained and progressive processes,altering the underwater landscape over *** results of this empirical investigation have significant implications for the design and constructio

关键词： local scour piles gap ratio attack angle

Triclosan-conjugated,Lipase-responsive Polymeric Micelles for Eradication of Staphylococcal Biofilms

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Chinese Journal of Polymer Science 2024年第6期42卷 718-728页

作者： Yan-qiang Huang Yuan-Feng Li Yong liu Lin-Qi Shi Guangxi Technology Innovation Cooperation Base of Prevention and Control Pathogenic Microbes with Drug Resistance Youjiang Medical University for NationalitiesBaise533000China Translational Medicine Laboratory the First Affiliated Hospital of Wenzhou Medical UniversityWenzhou325035China Wenzhou Institute University of Chinese Academy of SciencesWenzhou325001China State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials of Ministry of Educationand Institute of Polymer ChemistryCollege of ChemistryNankai UniversityTianjin300071China

Bacterial biofilms present a significant challenge in treating drug-resistant infections,necessitating the development of innovative *** this study,we introduce triclosan-conjugated,lipase-responsive polymeric micelles designed to exploit biofilm properties and serve as a responsive drug delivery *** micelles were created using an amphiphilic block polymer synthesized via ring-opening polymerization ofε-caprolactone(CL)and triclosan-containing cyclic trimethylene carbonate(MTC-Tri).Poly(ethylene glycol)(PEG-OH)acted as the macro-initiator,resulting in micelles with a PEG shell that facilitated their penetration into bacterial *** important advantage of our micelles lies in their interaction with local bacterial lipases within *** lipases triggered rapid micelle degradation,releasing triclosan in a controlled *** liberated triclosan effectively eliminated bacteria embedded in the ***,the triclosan-conjugated micelles displayed minimal toxicity to murine fibroblasts,indicating their biocompatibility and *** finding emphasizes the potential application of these micelles in combatting drug resistance observed in bacterial *** triclosan-conjugated,lipase-responsive polymeric micelles exhibit promising characteristics for addressing drug resistance in bacterial *** harnessing biofilm properties and implementing a responsive drug delivery system,we seek to provide an effective solution in the fight against drug-resistant bacteria.

关键词： Self-assembly Polymer prodrug Ring-opening polymerization Biofilm eradication Cytotoxicity

Heterostructure of 2D MoSe_(2) nanosheets vertically grown on bowllike carbon for high-performance sodium storage

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Nano Research 2024年第5期17卷 4023-4030页

作者： Nianxiang Shi Guangzeng liu Baojuan xi Xuguang An Changhui Sun Shenglin xiong School of Chemistry and Chemistry Engineering Qilu Normal UniversityJinan 250200China School of Chemistry and Chemical Engineering Shandong UniversityJinan 250100China School of Mechanical Engineering Chengdu UniversityChengdu 610106China

Transition metal dichalcogenides are attractive anode materials for sodium ion batteries(SIBs)due to their high theoretical capacity and large interlayer ***,its practical application is hampered by the sluggish kinetics of Na^(+)insertion and structure collapse caused by Na^(+)insertion/***,the heterostructures of MoSe_(2) nanosheets vertically growing on bowl-like carbon(MoSe_(2)@C)are designed and prepared by a template method coupled with selenization treatment to boost storage sodium *** hollow and collapse could provide enough storage space for Na^(+)and alleviate the volume expansion during the charge/discharge ***_(2) nanosheets vertically grown on carbon could expose more active sites for adsorbing Na^(+)to enhance the utilization rate of electrode ***,building heterostructures by combining different phase components could facilitate Na^(+)diffusion and advance reaction *** from these merits,the bowl-like MoSe_(2)@C shows outstanding reversible capacity(356.8 mAh·g^(-1) after 1500 cycles at 1 A·g^(-1))and remarkable rate performance(249.9 mAh·g^(-1)10 A·g^(-1)).

关键词： MoSe_(2)nanosheets bowl-like carbon heterostructure sodium ion batteries