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Chemical Research in Chinese Universities 2010年第4期26卷 636-639页

作者： ZHANG Cong-liang WANG yan College of Chemical Engineering Zhengzhou University Zhengzhou 450002 P. R. China

A shake-flask method was used to determine 1-octanol/water partition coefficients of ofloxacin, norfloxacin, lomefloxacin, ciprofloxacin, pefloxacin and pipemidic acid from 293.15 K to 323.15 K. The results show that 1-octanol/water partition coefficient of each quinolone increased with the increase of temperature. Based on the fluid phase equilibrium theory, the thermodynamic relationship of 1-octanol/water partition coefficient depending on the temperature was proposed, and the changes of enthalpy, entropy, and Gibbs free energy for quinolones partitioning in 1-octanol/water were determined, respectively. Quinolones molecules partitioning in 1-octanol/water was mainly an entropy driving process, during which the order degree of system decreased. The temperature effects of 1-octanol/water partition coefficient were investigated. The results show that its magnitude is the same as the values in the literature.

关键词： Quinolone 1-Octanol/water partition coefficient Thermodynamics

Experimental study of vertical and batter pile groups in saturated sand using a centrifuge shaking table

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Earthquake Engineering and Engineering Vibration 2022年第1期21卷 23-36页

作者： Zhang Jian Li Yurun yan Zhixiao Huang Da Rong Xian liang yan School of Civil and Transportation Engineering Hebei University of TechnologyTianjin 300401China Campus Construction and Management Hebei University of TechnologyTianjin 300401China

To study the dynamic response of vertical and batter pile groups in saturated sand,dynamic tests of these pile groups in saturated sand were carried out using the ZJU400 geotechnical centrifuge at Zhejiang *** following results were obtained.(1)As the motion intensity increased,the peak acceleration in soil layers at different depths significantly decreased,indicating that the soil stiffness was significantly reduced.(2)During the motion process,the instantaneous bending moment of the vertical and batter pile groups at different depths changed continuously,which had a strong relationship with the saturated sand *** the process of sand liquefaction,the residual bending moment generated by the batter pile was more obvious than that of the vertical pile.(3)With the liquefaction of the saturated sand,the distribution of the maximum bending moment of the vertical pile group changed,and the bending moment near the pile cap of the vertical and batter pile groups was always large.(4)In certain cases,the horizontal acceleration and dynamic displacement of the vertical pile cap were *** the motion intensity was large,residual displacement of the batter pile cap occurred.

关键词： centrifuge shaking table vertical and batter pile group saturated sand liquefaction dynamic response

Design and analysis of linear oscillating motor for linearpump application-magnetic field, dynamics and thermotics

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Frontiers of Mechanical Engineering 2016年第4期11卷 351-362页

作者： Zongxia JIAO Tianyi WANG liang yan School of Automation Science and Electrical Engineering BeihangUniversity Beijing 100191 China Shenzhen Research Institute ofBeihang University Shenzhen 518057 China

A linear oscillating motor is an electromagnetic actuator that can achieve short-stroke reciprocating movement directly without auxiliary transmission mechanisms. It has been widely used in linear pump applications as the source of power and motion. However, because of the demand of high power density in a linear actuation system, the performance of linear oscillating motors has been the focus of studies and deserves further research for high power density. In this paper, a general framework of linear oscillating motor design and optimization is addressed in detail, including the electromagnetic, dynamics, and thermal aspects. First, the electromagnetic and dynamics characteristics are modeled to reveal the principle for optimization. Then, optimization and analysis on magnetic structure, resonant system, and thermal features are conducted, which provide the foundation for prototype development. Finally, experimental results are provided for validation. As a whole, this process offers complete guidance for high power density linear oscillating motors in linear pump applications.

关键词： linear oscillating motor linear pump magnetic field motor optimization

Risks,challenges and strategies of power systems against the background of carbon neutrality

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Clean Energy 2023年第4期7卷 767-782页

作者： Qingbo Tan Xudong Li yan liang CITI University of Mongolia 999097-15141 UlaanbaatarMongolia North China Electric Power University 102206 BeijingChina Economics and Technology Research Institute of State Grid Shanxi Electric Power Company 030000 TaiyuanChina

Building a new power system with new energy as the main body is an important means of achieving the goal of carbon *** with the traditional power system,the new power system has great changes and challenges in its safety mechanism and balance *** on this,this paper focuses on the changes in the characteristics,functions and technologies of the new power system from the three sides of the source network and *** this basis,the challenges faced by the high proportion of new-energy power systems are summarized from six aspects:reliability,stability,economy,data intelligence,flexibility and ***,corresponding countermeasures,solutions and suggestions are put forward for the challenges of reliability,stability,economy,data intellectualization,flexibility and synergy,which provide ideas for the power guarantee of the new power system.

关键词： new power system reliability stability economy data intellectualization flexibility synergy

Programmed cell death may act as a surveillance mechanism to safeguard male gametophyte development in Arabidopsis

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Protein & Cell 2011年第10期2卷 837-844页

作者： Jian Zhang Chong Teng yan liang State Key Laboratory of Plant Genomics and National Plant Gene Research Center(Beijing) Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China

Programmed cell death(PCD)plays an important role in plant growth and development as well as in stress *** male gametophyte development,it has been proposed that PCD may act as a cellular surveillance mechanism to ensure successful progression of male gametogenesis,and this suicide protective machinery is repressed under favorable growth ***,the regulatory mechanism of male gametophyte-specific PCD remains ***,we report the use of a TdT-mediated dUTP nick-end labelingbased strategy for genetic screening of Arabidopsis mutants that present PCD phenotype during male gametophyte *** using this approach,we identified 12 mutants,designated as pcd in male gametogenesis(pig).pig mutants are defective at various stages of male gametophyte development,among which nine pig mutants show a microspore-specific PCD phenotype occurring mainly around pollen mitosis I or the bicellular *** PIG1 gene was identified by map-based cloning,and was found to be identical to ATAXIA TELANGIECTASIA MUTATED(ATM),a highly conserved gene in eukaryotes and a key regulator of the DNA damage *** results suggest that PCD may act as a general mechanism to safeguard the entire process of male gametophyte development.

关键词： programmed cell death male gametophyte PIG TdT-mediated dUTP nick-end labeling ATM

Preparation and characterization of pH-responsive metal-polyphenol structure coated nanoparticles

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Food Science and Human Wellness 2024年第3期13卷 1303-1310页

作者： Qile Xia yan liang Ailing Cao yan Cao Luyun Cai Key Laboratory of Post-Harvest Handling of Fruits Food Science InstituteZhejiang Academy of Agricultural SciencesHangzhou 310021China Ningbo Research Institute College of Biosystems Engineering and Food ScienceZhejiang UniversityNingbo 315100China School of Biological and Chemical Engineering Zhejiang Engineering Research Center for Intelligent Marine Ranch EquipmentNingboTech UniversityNingbo 315100China College of Food Science and Engineering Bohai UniversityJinzhou 121013China Hangzhou Customs District Hangzhou 310007China

In this paper,tannic acid(TA)and Fe~(3+)were added to form a layer of metal-polyphenol network structure on the surface of the nanoparticles which were fabricated by zein and carbon quantum dots(CQDs)encapsulating phlorotannins(PTN).pH-Responsive nanoparticles were prepared successfully(zein-PTN-CQDs-Fe-~Ⅲ).Further,the formation of composite nanoparticles was confirmed by a series of characterization *** zeta-potential and Fourier transform infrared spectroscopy data proved that electrostatic interaction and hydrogen bonding are dominant forces to form *** encapsulation efficiency(EE)revealed that metal-polyphenol network structure could improve the EE of *** analysis and differential scanning calorimetry experiment indicated the thermal stability of zein-PTN-CQDs-Fe~Ⅲnanoparticles increased because of metal-polyphenol network *** pH-responsive nanoparticles greatly increased the release rate of active substances and achieved targeted release.

关键词： Metal Phlorotannins Nanoparticles pH-Responsive Characterization

Fatty acids and algal lipids as precursors of chlorination by-products

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Journal of Environmental Sciences 2012年第11期24卷 1942-1946页

作者： yan liang Yuen Shan Lui Huachang Hong Croucher Institute for Environmental Sciences(CIES)and Department of Biology Hong Kong Baptist UniversityKowloon TongHong KongChina College of Geography and Environmental Sciences Zhejiang Normal UniversityJinhua 321004China Centre for Food Safety and Environmental Technology Guangzhou Institute of Advanced TechnologyChinese Academy of SciencesGuangzhou 511458China

Six common algal fatty acids （FAs） with different numbers of double bonds, lipophilic fractions and proteins extracted from the diatom Navicula pelliculosa and algal ceils were chlorinated to evaluate their potential in generating disinfection by-products （DBPs）. The result showed that the more double bonds in the FAs, the higher the amounts of chloroform and dichloroacetic acid （DCAA） produced, but such a pattern was not observed for trichloroacetic acid （TCAA）. Based on the previously reported composition of fatty acids in algal lipids, the DBP generation potentials of algal lipids were calculated. These predicted values were much lower than those measured in the chlorinated algal lipophilic fraction, suggesting unknown lipophilic fraction（s） served as potent DBPs precursors. Another calculation attempted to predict DBP production in algal cells based on algal lipid and protein composition, given quantified measured DBP production per unit algal lipid and proteins. The analysis showed that the observed DBP production was similar to that predicted （〈 35% difference）, suggesting that algal biochemical compositions may serve as a bioindicator for preliminary estimation of chloroform, DCAA and TCAA formation upon chlorinating algae.

关键词： algal lipid algal-derived organic materials chlorination by-products fatty acids

Functional tumor imaging based on inorganic nanomaterials

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Science China Chemistry 2017年第11期60卷 1425-1438页

作者： Jiangfeng Du Xiao Zhang liang yan Rui Chen School of Radiation Medicine and Protection & School for Radiological and Interdisciplinary Sciences (RAD-X) Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions Soochow University CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety Institute of High Energy Physics Chinese Academy of Sciences CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology of China College of Materials Sciences and Opto-Electronic Technology University of Chinese Academy of Sciences

Inorganic nanomaterials have attracted substantial research interest due to their unique intrinsic physicochemical properties. We highlighted recent advances in the applications of inorganic nanoparticles regarding their imaging efficacy, focusing on tumor-imaging nanomaterials such as metal-based and carbon-based nanomaterials and quantum dots. Inorganic nanoparticles gain excellent in vivo tumor-imaging functions based on their specific characteristics of strong near-infrared optical absorption and/or X-ray attenuation capability. The specific response signals from these novel nanornaterials can be captured using a series of imaging techniques, i.e., optical coherence tomography （OCT）, X-ray computed tomography （CT） imaging, two-photon luminescence （TPL）, photoacoustic tomography （PAT）, magnetic resonance imaging （MRI）, surface-enhanced Raman scattering （SERS） and positron emission tomography （PET）. In this review, we summarized the rapid development of inorganic nanomaterial applications using these analysis techniques and discussed the related safety issues of these materials.

关键词： imaging gold nanoparticles carbon nanotube graphene quantum dots toxicity

Effects of Hot Steam Injection from the Slot at the Trailing Edge on Turbine Nozzle Vane Flow Field

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Journal of Thermal Science 2008年第4期17卷 298-304页

作者： liang Xu Peigang yan Hongyan Huang Wanjin Han School of Energy Science ＆ Engineering Harbin Institute of Technology Harbin 150001

Moisture removal slot configurations with three different opening widths are in turn set at the trailing edges of a turbine hollow guide *** flow fields are analyzed by two-phase flow numerical simulation of solving the steady three dimensional Reynolds averaged Navier-Stokes equations on the basis of the real water vapor thermo-physical properties,and the blade temperature field is solved by the fluid-solid *** parame- ter is introduced as a measure to evaluate the economic cost of energy conversion *** results indicate that the bigger slot allow lower quality of hot steam in the case of the equivalent injected quantity,while it has a higher exergy effective efficiency of the mixing process in the cascade *** hot steam injecting at the trailing edges has an optimal injected mass flow rate for a relatively large slot,on this point the exergy effective efficiency is the maximum,namely the flow loss is the minimum.

关键词： wet steam stationary blade moisture removal slot exergy analysis