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Chinese Medical Journal 2008年第3期121卷 280-282页

作者： ZHANG Gen-sheng XU Zhi-hao CUI Wei ZHOU Fang XIA Yi li Wen li li-bin SHEN Hua-hao Intensive Care Unit Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310009 China Departmnent of Respiratory Medicine Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310009 China Department of Pathology Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310009 China

Non-Hodgkin＇s lymphoma （NHL） affects thoracic structures, particularly mediastinum and lung parenchyma, in up to 43% of patients at some stage in the course of the disease,1 Endobronchial involvement, however, is extremely rare, even in the presence of advanced disease. Since the first report of endobronchial NHL in 1955,2 there were few reports on the cases with this disease identified by bronchoscopic examination in the English literature.3-14To our knowledge, the patient described in this report is an extremely rare case presenting with respiratory failure as the initial manifestation requiring intubation and mechanical ventilation soon after admission.

关键词： non-Hodgkin's lymphoma endobronchial respiration failure

Relationship between Trp64Arg mutation in the β3-adrenergic receptor gene and metabolic syndrome： a seven-year follow-up study

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Chinese Medical Journal 2010年第17期123卷 2375-2378页

作者： ZHU Lue-yun HU li-ye li Xiao-ling WANG Guang-yu SHAN Wei MA li-cheng WANG Xiu-hui Department of Endocrinology Bethune International Peace Hospital Shijiazhuang Hebei 050082 China

Background It has been shown that the β3-adrenergic receptor （β3-AR） gene Trp64Arg mutation was closely related to obesity and insulin resistance, and may be related to the prevalence of metabolic syndrome （MS）. The aim of this study was to investigate the relationship between the 33-AR gene mutation and the prevalence of MS. Methods A seven-year follow-up study was initiated in 2000, with 496 samples of simplex obese subjects （body mass index ≥25 kg/m2） and 248 normal-weight subjects. According to the β3-AR genotypes, the subjects were classified as Trp64 homozygote group and Arg64 carrier group and after 7 years the prevalence of MS was determined. Results According to the baseline profile, there were no significant differences in the adiposity, blood pressure, lipid profile, fasting plasma glucose and fasting insulin between Trp64 homozygote group and Arg64 carrier group either in obesity or normal-weight subjects. The results of follow-up study indicated that in obese men the prevalence rate of MS was much higher in Arg64 carrier group than that in Trp64 homozygote group （54.76% vs. 40.85%, P 〈0.05）, but there was no statistical difference in women of the above groups. The prevalence rate of MS in obese men of both Trp64 homozygote group and Arg64 carrier obese group were obviously higher than that in women of the above groups （40.85% vs. 18.27% and 54.76% vs 21.28%, all P 〈0.005）. Differences were not statistically significant in the prevalence of MS for normal weight Trp64 homozygote group and normal weight Arg64 carrier group, either between men, between women, or between men and women. Comparison of populations indicated that no matter with the β3-AR gene mutation or not, the prevalence of MS in obese subjects was significantly higher than normal weight subjects （X2=28.240 and x2=15.586, all P 〈0.005）. Logistic analysis showed that the mutation of β3-AR gene was associated with the prevalence of MS in men.

关键词： metabolic syndrome β3-adrenergic receptor polymorphism prospective study

重力及其释放下空间机械臂驱动力差异及模型研究

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电机与控制学报 2017年第12期21卷 66-74,84页

作者：秦利李倩闫莉莉刘福才王文魁燕山大学电气工程学院河北秦皇岛066004 燕山大学材料科学与工程学院河北秦皇岛066004

为降低空间机构系统能耗,减小驱动力地面设计裕度,提高空间机构控制精确度,以四自由度仿人机械臂为对象,研究不同重力环境下的驱动力差异及关键影响因素。首先基于Klein算子与虚功原理建立了考虑关节摩擦的四自由度仿人机械臂动力学模... 详细信息

为降低空间机构系统能耗,减小驱动力地面设计裕度,提高空间机构控制精确度,以四自由度仿人机械臂为对象,研究不同重力环境下的驱动力差异及关键影响因素。首先基于Klein算子与虚功原理建立了考虑关节摩擦的四自由度仿人机械臂动力学模型。然后通过仿真研究不同重力环境下摩擦、关节角速度、末端负载对驱动力矩的影响,并对影响空间驱动力矩的关键因素进行分析。进而参照仿真研究搭建试验平台,在关节轴线不同取向条件下进行驱动力矩差异研究,试验验证了仿真分析的正确性。最后基于试验结果修正摩擦模型并采用PSO算法辨识模型参数,得到适用于不同重力环境下的关节摩擦模型,改进了机械臂的理论建模结果。

关键词：空间机械臂重力影响驱动力摩擦模型地面试验

New Observation of Na2 4^3∑g^＋ State by Pulsed Perturbation Facilitated Optical-Optical Double Resonance Spectroscopy

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Chinese Journal of Chemical Physics 2006年第1期19卷 11-14页

作者： Zheng Chen Cheng-zhe Cui Yao-ming liu li li V. B. Sovkov V. S. Ivanov Department of Physics and Key Laboratory of Atomic and Molecular Nanosciences Tsinghua Uni-versity Beijing 100084 China V. A. Fock Institute of Physics St. Pertersburg 5tare UniversityPetrodvorets St. Petersburg 198504 Russia

Sixty-five new vibronic levels of the Na2 4^3∑g^＋ state have been observed in the 33900-35200 cm^-1 energy region above the potential minimum of the ground state by pulsed perturbation facilitated optical-optical double resonance （PFOODR） fluorescence excitation spectroscopy. These new data fill the gap between the low-v levels mainly observed by continuous wave （CW） PFOODR spectroscopy and the high-v levels above the 3s＋3d limit observed by pulsed PFOODR with predissociation detection, Molecular constants are fitted below potential shelf around the 3s＋3d atomic limit with previously published data （mainly observed by CW PFOODR） and these new data. RKR potential curve has been calculated with the new constants. The constants are： Te= 32127.090 cm^-1,ωe=121.4099（0.20720） cm^-1, Be = 0.116287（0.0002300） cm^-1, Re=3.551 A, An error of the RKR potential curve of J. Chem. Phys. 108, 7707 （1998） is corrected.

关键词： Na2 Triplet states PFOODR 4^3∑g^+ state state Rydberg states

基于邻苯二甲酰-L-丙氨酸配体的两例Cu(Ⅱ)纯手性同质多晶配合物:合成与结构（英文）

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无机化学学报 2018年第1期34卷 83-91页

作者：李孟丽常旭曾艳丽宋会花河北师范大学化学与材料科学学院石家庄050024 深州市中学深州053800

合成了2例Cu(Ⅱ)的纯手性同质多晶[CuL_2(Phen)](HL=邻苯二甲酰-L-丙氨酸,Phen=1,10-菲咯啉),并对其进行了表征。X射线单晶衍射测定表明,邻苯二甲酰-L-丙氨酸在2例配合物中采取了相同的配位方式,Cu(Ⅱ)原子具有变形的八面体配位环境,分... 详细信息

合成了2例Cu(Ⅱ)的纯手性同质多晶[CuL_2(Phen)](HL=邻苯二甲酰-L-丙氨酸,Phen=1,10-菲咯啉),并对其进行了表征。X射线单晶衍射测定表明,邻苯二甲酰-L-丙氨酸在2例配合物中采取了相同的配位方式,Cu(Ⅱ)原子具有变形的八面体配位环境,分别和2个邻苯二甲酰-L-丙氨酸离子上的2个羧基氧原子,1个1,10-菲咯啉的2个氮原子配位。不同的是这2例同质多晶显示出不同的颜色,并且配合物1属于单斜晶系,C2空间群,配合物2属于正交晶系,P2_12_12_1空间群。配合物1通过π…π堆积作用形成一维链状结构,配合物2是简单小分子结构。此外,DFT理论研究表明,配合物1具有较低的能量,稳定性更高。

关键词：手性铜(Ⅱ)配合物晶体结构同质多晶异构体

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基于多色集合理论的冲压工艺规划建模研究

计算机集成制造系统 2006年第7期12卷 990-995页

作者：姜莉莉赵苏晋李宗斌广东工业大学机电工程学院广东广州510090 西安交通大学机械工程学院CIMS所陕西西安710049 西安交通大学机械制造系统工程国家重点实验室陕西西安710049

在研究冲压工艺加工需求和加工工序的基础上,应用多色集合理论建立了冲压工艺规划的数学模型。该模型包括围道矩阵和多色图等两个部分,多色图描述冲压工序的相互作用。应用此模型研究了一种冲压工艺路径求解算法,能根据加工要求搜索工... 详细信息

在研究冲压工艺加工需求和加工工序的基础上,应用多色集合理论建立了冲压工艺规划的数学模型。该模型包括围道矩阵和多色图等两个部分,多色图描述冲压工序的相互作用。应用此模型研究了一种冲压工艺路径求解算法,能根据加工要求搜索工序路线,求解出零件的冲压工艺路线。开发了一个冲压工艺规划原型系统,并以一个圆筒类零件为例,对所提出的模型与算法进行了验证。

关键词：多色集合多色图冲压工艺规划

Simultaneously Improved Curing,Mechanical,Antioxidative Properties and Reduced ZnO Loading of Silica Filled NR Composites by Incorporation of Low-cost Crude Carbon Dots via Conventional Melt-milling Method

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Chinese Journal of Polymer Science 2024年第6期42卷 815-825页

作者： Chao-Ying Sun Hai-Jun Ji li-Wei li Hui Yang Xiao-Peng An Yi-Ping Chen Ming-Jian Han Can Jiang li-Qun Zhang Peng Yu Run-Guo Wang State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing100029China School of Materials Science and Engineering Wuhan Institute of TechnologyWuhan430205China

Rubbers or elastomers play an important role in hi-tech technology and civilian daily life because of their unique and strategical ***,the rubber additives are essential components for rubbers’practical ***,developing novel multifunctional additives has attracted increasing research *** this work,low-cost crude carbon dots(CCDs)were used as multifunctional additives for natural rubber/silica system(without any additional modification)through industrial compatible melt-mixing *** results revealed that the CCDs could disperse well in the NR/silica system,and they could not only endow the rubber compound with excellent anti-aging capability due to CCDs’radical scavenging activity because of their plenty of nitrogen-containing species,but also improve the curing rate and mechanical performance of the rubber ***,the CCDs could reduce the rolling resistance of the rubber composites(tanδvalue at 7%strain of the rubber composite could be decreased by 34%),which is promising for the application of energy-saving tire ***,the addition of CCDs could effectively reduce the ZnO dosage by at least 40%in the rubber composite without deteriorating its ***,this work provides valuable guidance to develop novel cheap yet effective additives for the elastomer.

关键词： Natural rubber Crude carbon dots Antioxidant ZnO reduction Vulcanization

基于关联设备系统拓扑关系描述的可靠性计算方法及应用

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铁道学报 2014年第8期36卷 32-37页

作者：王艳辉李莉洁贾利民秦勇李曼北京交通大学交通运输学院北京100044 北京交通大学轨道交通控制与安全国家重点实验室北京100044

从组成关联设备系统单元间3种关联关系(直接关联无作用、直接关联单向作用、直接关联相互作用)出发,将组成设备系统的单元作为节点、单元之间的作用关系作为节点之间的边,构建微观至宏观的系统可靠性网络模型;分析不同关联关系下和不同... 详细信息

从组成关联设备系统单元间3种关联关系(直接关联无作用、直接关联单向作用、直接关联相互作用)出发,将组成设备系统的单元作为节点、单元之间的作用关系作为节点之间的边,构建微观至宏观的系统可靠性网络模型;分析不同关联关系下和不同寿命分布下子系统可靠性的形式化描述及其计算方法,并通过实例进行了验证。研究表明,本文提出的方法可为关联系统单元间作用关系复杂且寿命分布不同的系统可靠性计算提供一种新的研究思路。

关键词：设备系统寿命分布可靠性计算关联

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自身免疫性胰腺炎临床特征分析

中华内科杂志 2010年第11期49卷 943-946页

作者：吴丽丽李闻解放军总医院消化科北京100853

目的探讨自身免疫性胰腺炎（autoimmune pancreatitis,AIP）的临床特点,提高对AIP的认识,降低误诊率.方法分析2006-2009年期间在解放军总医院诊治的AIP患者的临床表现、影像及病理学特征和诊疗经过,并与1995-2005年期间的本院资料进... 详细信息

目的探讨自身免疫性胰腺炎（autoimmune pancreatitis,AIP）的临床特点,提高对AIP的认识,降低误诊率.方法分析2006-2009年期间在解放军总医院诊治的AIP患者的临床表现、影像及病理学特征和诊疗经过,并与1995-2005年期间的本院资料进行对比.结果 2006-2009年期间诊治8例AIP患者（男6例,女2例）,年龄35～69（52.4±9.4）岁.主要临床表现为黄疸6例（6/8）,腹痛5例（5/8）,伴有其他免疫疾病4例（4/8）.影像学见胰腺局部肿大3例（3/8）,弥漫性肿大5例（5/8）,其胰周均可见＂香蕉皮样＂囊状环,胰管不规则狭窄.病理检查见胰腺组织、胆管、涎腺及肝内可见大量淋巴细胞和浆细胞浸润及实质纤维化.7例（7/8）口服泼尼松治疗后临床表现、实验室及影像学表现均明显好转.我院1995-2005年期间资料显示,95.7%（22/23）误诊为胆道或胰腺癌,91.3%（21/23）行开腹手术,自2006年以后无一例出现误诊（0/8）.结论 AIP是全身免疫系统异常体现在胰腺的一种损伤,常伴发其他免疫性疾病,综合免疫指标检测、影像学、病理学检查及试验性糖皮质激素治疗等可获确诊.

关键词：胰腺肿瘤免疫球蛋白G 自身免疫性胰腺炎

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恶臭假单胞菌生物滴滤塔净化甲苯废气的研究

环境科学 2007年第8期28卷 1866-1872页

作者：张书景李坚李依丽金毓峑孙莉北京工业大学环境与能源工程学院北京100022

在接近于工业化应用的非稳态条件下，采用恶臭假单胞菌为菌源接种生物滴滤塔，处理含甲苯废气．研究了滤塔的挂膜启动情况与稳定运行阶段抗负荷变化能力，并对滤塔内生物膜微观结构进行了观察分析．在停留时间为548和43．28，进气甲苯... 详细信息

在接近于工业化应用的非稳态条件下，采用恶臭假单胞菌为菌源接种生物滴滤塔，处理含甲苯废气．研究了滤塔的挂膜启动情况与稳定运行阶段抗负荷变化能力，并对滤塔内生物膜微观结构进行了观察分析．在停留时间为548和43．28，进气甲苯浓度为544-1044mg·m^-3，环境温度为17-26℃的操作条件下，滤塔气体出口检测不到甲苯，最大体积去除负荷为105．35g·（m^3·h）^-1．结果表明，在非稳定条件下，以未经甲苯驯化筛选的恶臭假单胞菌作为菌源降解甲苯废气是可行的；稳定运行阶段滤塔具有较强的抗负荷变化能力，进气浓度与停留时间的变化不会引起处理性能的下降；通过控制营养液添加间隔可以较好地控制生物膜的快速增长；滤塔内微生物菌落发生了变化，大量微孔结构的存在证明了微孔的吸附是生物膜降解甲苯的重要前提．

关键词：生物滴滤塔恶臭假单胞菌甲苯生物膜吸附