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Development of the fast arcing protection for ECRH system on the HL-2A tokamak

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核聚变与等离子体物理 2007年第1期27卷 44-47页

作者： li xiu-juan RAO Jun WANG Ming-wei WANG Xue-yun li Bo Southwestern Institute of Physics Chengdu 610225

1 Introduction A series of engineering tests and physical experiments,including ECRH[1],was carried out on the HL-2A tokamak in 2005.A fast arcing protection system[2] was developed to ensure operating of ECRH facilit... 详细信息

关键词：弧阈值响应时间托卡马克装置

Risk assessment of heavy metals in topsoil along the banks of theYangtze River in Huangshi, China

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Journal of Groundwater Science and Engineering 2017年第2期5卷 162-172页

作者： liN Dan JIN Meng-gui li xiu-juan College of Civil Engineering and Architecture Zhejiang University Hangzhou 310058 China Laboratory of Basin Hydrology and Wetland Eco-restoration & School of Environmental Studies China University of Geosciences Wuhan 430074 China Zhejiang Institute of Geology and Mineral Resources Hangzhou 310007 China Guangdong Province Geological Environmental Monitoring Station Guangzhou 510510 China

High concentrations of heavy metal in farmland threatens food production and human health. Our study assesses soil quality and the distribution of Cd, Cr, Cu, Zn, Pb and Ni, to identify possible sources of heavy metals along the banks of the Yangtze River in Huangshi. Heavy metal concentrations of 22 topsoil samples were measured using the inductively coupled plasma mass spectrometry instrument and data was analyzed by multivariate statistic approaches. Heavy metal contamination risk assessment was performed using a combination of the Nemerow multi-factor index method, the Hakanson potential ecological risk index method and the Muller index of geo-accumulation method. These methods determined similar results indicating that cadmium(Cd) poses a health risk to residents at the study site while Cr, Cu, Zn, Pb and Ni do not. The Nemerow multi-factor index method demonstrated that 18 samples were heavily polluted, three moderately polluted and one lightly polluted. The Muller index of geo-accumulation method found ten samples were moderately to strongly polluted by Cd, five were moderately polluted, six were lightly to moderately polluted and one was lightly polluted. The Hakanson potential ecological risk index method proved six samples were strongly polluted, seven were moderately polluted and nine were lightly polluted. Since our sampling sites were all in agricultural lands, we recommend the potential ecological risk index method as the most effective given it not only considers the range of pollutants contributing to soil pollution but factors in heavy metals toxicity. We are apt that the source of the high concentrations of Cd found in topsoil is derived from alluvial sediments upstream of the Yangtze River with a high percentage of residual speciation and a low percentage of exchangeable speciation distribution of Cd. This in turns indicates that a high concentration of Cd in soil had little impact on the natural environment. However, 31.9% of the iron-manganese o

关键词： Heavy metals Risk assessment Soil chemical analysis The Yangtze River Huangshi

Solid-phase Microextraction with Benzoxy-calix[6]arene Fiber Coupled to Gas Chromatography for the Analysis of Polycyclic Aromatic Hydrocarbons in Water

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Chemical Research in Chinese Universities 2011年第2期27卷 198-202页

作者： YE Chang-wen ZHANG Xue-na HUANG Jiang-yan li xiu-juan PAN Si-yi College of Food Science ＆ Technology Huazhong Agricultural University Wuhan 430070 P. R. China

Headspace solid-phase microextraction（HS-SPME） with sol-gel calix[6]arene-containing fiber followed by gas chromatography with a flame ionization detector was used to examine the composition and distribution of seven polycyclic aromatic hydrocarbons（PAHs） in water. The novel SPME fiber exhibited higher extraction efficiency to PAHs compared with poly（dimethylsiloxane） and other calixarene-containing fibers. Extraction/retention mechanism based on the interactions between calixarenes and PAHs was discussed. Owing to the good selectivity and high extraction capability of this calixarene fiber, low detection limits were obtained in a range of 0.34―6.50 ng/L and the relative standard deviation values were ≤12.3% for all of the analytes. The linear ranges of the proposed method were five orders of magnitude for the tested compounds, with linear correlation coefficients（r） greater than 0.998. The method was applied to the determination of polycyclic aromatic hydrocarbons in nine water sources in Wuhan City, China. Standard addition method was selected for the quantification and the recovery values were in a satisfactory range. Total PAHs concentrations in the nine surface water samples were found to vary between undetectable and 8.840 μg/L with two- and three-ring PAHs predominating.

关键词： Polycyclic aromatic hydrocarbon Solid-phase microextraction Calixarene Gas chromatography Water

Cloning and Characterization of a Novel cDNA Encoding Late Embryogenesis-Abundant Protein 5 like (LEA-5) Gene from Cara Cara Navel Orange Fruit (Citrus sinensis Osbeck)

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Agricultural Sciences in China 2006年第4期5卷 272-276页

作者： TAO Neng-guo YE Jun-li XU juan DENG xiu-xin National Key Laboratory of Crop Genetic Improvement National Center of Crop Molecular Breeding Huazhong Agricultural University Wuhan 430070 P.R.China

LEA5 gene was postulated related with both stress and hormone responses. In an attempt to find genes exclusively expressed during fruit ripening of Cara Cara navel orange, a novel cDNA clone encoding late embryogenesis-abundant protein 5 like gene （CitLEA5-1） was obtained. It was 582 bp in length, containing 97 deduced amino acids. Compared with the stress-induced LEA5 from leaves of Citrus sinensis, CitLEA5-1 had a shorter 3′ untranslated region （UTR）. Semi-quantitative RT-PCR analysis revealed that CitLEA5-1 was transcriptional regulated during fruit ripening of Cara Cara navel orange.

关键词： Citrus cloning characterization late embryogenesis-abundant protein

Soil Nutrients in Intensive Agricultural Areas with Different Land-Use Types in Qingzhou County, China

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Pedosphere 2007年第2期17卷 165-171页

作者： ZHAO Geng-Xing li xiu- juan WANG Ri-Yan li Tao YUE Yu-De College of Resources and Environment Shandong Agricultural University Tai＇an 271018 （China）. Soil ＆ Fertilizer Working Station of Shandong Jinan 250100 （China） Qingzhou Agricultural Bureau Qingzhou 262500 （China）

On the basis of the data obtained from a field survey, the relationship between land use and soil nutrients was evaluated in Qingzhou County, Shandong Province, China, through a statistical analysis of differences in 17 nutrients in five types of cultivated land. The results showed significant effects (P lizer applied to vegetable crops, the concentrations of most soil nutrients, with exception of available Si and micronutrients, were higher than those in grain cropland. Grain cropland had a significantly lower total salt content (P < 0.01) and tended to have a higher soil pH than vegetable land. Within subtypes of land use, dry land, irrigable land, and open-air vegetable land had the highest coefficient of variation (CV) for available P, whereas protected vegetable land had the highest CV for total N and available S. In general, land-use types had greater impact on macronutrients than on secondary nutrients and micronutrients.

关键词： cultivated land land-use type Qingzhou County soil nutrients

Ziyin Huatan Recipe, a Chinese herbal compound, inhibits migration and invasion of gastric cancer by upregulating RUNX3 expression

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Journal of Integrative Medicine 2022年第4期20卷 355-364页

作者： Shang-jin Song Xuan liu Qing Ji Da-zhi Sun li-juan xiu Jing-yu Xu Xiao-qiang Yue Department of Traditional Chinese Medicine Changzheng HospitalNaval Medical UniversityShanghai 200003China Strategic Support Force Xingcheng Special Duty Sanatorium Xingcheng 125100Liaoning ProvinceChina Cancer Institute Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 201203China

Objectives: Ziyin Huatan Recipe(ZYHT), a traditional Chinese medicine comprised of lilii Bulbus, Pinelliae Rhizoma, and Hedyotis Diffusa, has shown promise in treating gastric cancer(GC). However, its potential mechanism has not yet been clearly addressed. This study aimed to predict targets and molecular mechanisms of ZYHT in treating GC by network pharmacology analysis and to explore the role of ZYHT in GC both in vitro and in ***: Targets and molecular mechanisms of ZYHT were predicted via network pharmacology analysis. The effects of ZYHT on the expression of metastasis-associated targets were further validated by Western blot and quantitative real-time polymerase chain reaction. To explore the specific molecular mechanisms of the effects of ZYHT on migration and invasion, the runt-related transcription factor 3(RUNX3) gene was knocked out by clustered regularly interspaced short palindromic repeats/Cas9, and lentiviral vectors were transfected into SGC-7901 cells. Then lung metastasis model of GC in nude mice was established to explore the anti-metastasis effect of ZYHT. Western blot and immunohistochemistry were used to explore the impact of ZYHT on the expression of metastasis-related proteins with or without RUNX3 ***: The network pharmacology analysis showed that ZYHT might inhibit focal adhesion, migration,invasion and metastasis of GC. ZYHT inhibited the proliferation, migration and invasion of GC cells in vitro via regulating the expression of metastasis-associated targets. Knocking out RUNX3 almost completely reversed the cell phenotypes(migration and invasion) and protein expression levels elicited by *** vivo studies showed that ZYHT inhibited the metastasis of GC cells to the lung and prolonged the survival time of the nude mice. Knocking out RUNX3 partly reversed the metastasis of GC cells to the lung and the protein expression levels elicited by ***: ZYHT can effectively inhibit the invasion and migration of GC in

关键词： Ziyin Huatan Recipe Gastric cancer Traditional Chinese medicine Metastasis Runt-related transcription factor 3

Intravitreal bevacizumab injection for chronic central serous chorioretinopathy

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Chinese Medical Journal 2010年第15期123卷 2145-2147页

作者： li xiu-juan ZHANG Jin-song Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China

Central serous chorioretinopathy （CSC） is characterized by an idiopathic serous neurosensory detachment primarily affecting the *** most cases,the disorder is self-limited and spontaneously in 4 to 6 months, and the... 详细信息

关键词： central serous chorioretinopathy intravitreal bevacizumab retinal pigment epithelium detachment

Xiaotan Tongfu granules contribute to the prevention of stress ulcers

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World Journal of Gastroenterology 2013年第33期19卷 5473-5484页

作者： Bing Yan Jun Shi li-juan xiu Xuan liu Yu-Qi Zhou Shou-Han Feng Can Lv xiu-Xia Yuan Yin-Cheng Zhang Yong-Jin li Pin-Kang Wei Zhi-Feng Qin Department of Traditional Chinese Medicine Changzheng HospitalSecond Military Medical University

AIM:To investigate the efficacy and potential mechanism of Xiaotan Tongfu granules(XTTF)in stress ***:One hundred sixty rats were randomly divided into 4 groups(n=10)as follows:the model group(MP group),the control group(CP group),the ranitidine group(RP group)and the XTTF granule group(XP group).Rats in the MP group received no drugs,rats in the CP group received 0.2 mL of a 0.9%sodium chloride solution via oral gavage,and rats in the RP and XP groups received the same volume of ranitidine(50 mg/kg)or XTTF granule(4.9 g/kg).The cold-restraint stress model was applied to induce stress ulcers after 7 consecutive days of drug ***,rats were sacrificed at 0,3,6 and24 *** pH was measured by a precise pH meter;gastric emptying rate(GER)was measured by using a methylcellulose test meal;myeloperoxidase activity(MPO),macrophage migration inhibitory factor(MIF),proliferating cell nuclear antigen(PCNA),and heat shock protein 70(HSP70)were measured by immunohistochemical staining;and mucosal cell apoptosis was measured by transferase dUTP nick end ***:In the cold-restraint stress model,the development of stress ulcers peaked at 3 h and basically regressed after 24 *** lesions were significantly different in the RP and XP groups at each time ***,although this index was much lower in the RP group than in the XP group immediately following stress induction(7.00±1.10 vs 10.00±1.79,P<*** gastric pH,between the RP and XP groups,we detected a statistically significant difference immediately after stress induction(0 h:4.56±0.47 vs 3.34±0.28,P<0.05)but not at any of the subsequent time *** GER,compared to the RP group,GER was remarkably elevated in the XP group because a statistically significant difference was detected(3 h:46.84±2.70 vs 61.16±5.12,P<0.05;6 h:60.96±6.71 vs 73.41±6.16,P<0.05;24 h:77.47±3.17 vs 91.31±4.34,P<0.05).With respect to MPO and MIF,comparisons between the RP and XP groups

关键词： Stress ulcer Xiaotan Tongfu granule Inflammation Heat shock protein 70 Proliferation and apoptosis Gastric emptying rate

Q fever endocarditis with multi-organ complication： a case report

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Chinese Medical Journal 2006年第18期119卷 1580-1582页

作者： ZHANG li-juan FU xiu-ping ZHANG Jing-shan Department of Rickettsia National Institute of Communicable Disease Control and Prevention Chinese Centre for Disease Control and Prevention Beijing 102206 China

Qfever is a worldwide zoonosis and its agent is Coxiella burnetii （C. burnetii）. There are two forms of Q fever： acute and chronic. Acute Q fever is caused by primary infection with C. burnetii and its main clinical features are high fever, granulomatous hepatitis and atypical pneumonia. Acute Q fever is extremely prone to develop chronic infection if it is improperly treated. Endocarditis is the main characteristic of chronic Q fever and it accounts for 3% to 5% of all cases of endocarditis.

关键词： Q fever Coxiella burnetii endocarditis