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Effectiveness of cardioneuroablation in different subtypes of vasovagal syncope

Journal of Geriatric Cardiology 2024年第6期21卷 651-657页

作者： Bin TU Zi-Hao LAI Ai-Yue CHEN Zhi-Yuan WENG Si-Min CAI Zhu-Xin ZHANG li-Kun ZHOU li-hui zheng Yan YAO Arrhythmia Center Fuwai HospitalNational Center for Cardiovascular DiseasesNational Key LaboratoryChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Cardiac Center Beijing Chaoyang HospitalCapital Medical UniversityBeijingChina Cardiovascular Department The First Affiliated HospitalFujian Medical UniversityFujian Institute of HypertensionFujianChina Department of Cardiovascular The Second Affiliated Hospital of Zhejiang University School of MedicineZhejiangChina

BACKGROUND Cardioneuroablation(CNA)has shown encouraging results in patients with vasovagal syncope(VVS).However,data on different subtypes was *** This observational study retrospectively enrolled 141 patients[mean age:40±18 years,51 males(36.2%)]with the diagnosis of *** characteristics among different types of VVS and the outcomes after CNA were *** After a mean follow-up of 4.3±1.5 years,41 patients(29.1%)experienced syncope/pre-syncope events after ***/pre-syncope recurrence significantly differed in each subtype(P=0.04).The cardioinhibitory type of VVS had the lowest recurrence rate after the procedure(n=6,16.7%),followed by mixed(n=26,30.6%)and vasodepressive(n=9,45.0%).Additionally,a significant difference was observed in the analyses of the Kaplan-Meier survival curve(P=0.02).Syncope/pre-syncope burden was significantly reduced after CNA in the vasodepressive type(Pline deceleration capacity(DC)level than those without(7.4±1.0 ms vs.9.0±1.6 ms,P=0.01).Patients with DC<8.4 ms had an 8.1(HR=8.1,95%CI:2.2-30.0,P=0.02)times risk of syncope/pre-syncope recurrence after CNA compared to patients with DC≥8.4 ms,and this association still existed after adjusting for age and sex(HR=8.1,95%CI:2.2-30.1,P=0.02).CONCLUSIONS Different subtypes exhibit different event-free *** vasodepressive type exhibited the lowest event-free rate,but those patients with DC≥8.4 ms might benefit from CNA.

关键词： syncope subtypes diagnosis

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Ultrasound-guided stellate ganglion blockade: an appealing tactic for cardiac electrical storm

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Journal of Geriatric Cardiology 2023年第5期20卷 376-382页

作者： Zi-Hao LAI li-hui zheng Yan YAO Arrhythmia Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Ventricular arrhythmia(VA)is a life-threatening cardiac *** VA occurs three times or more within 24 h and interventions are required,it is defined as an electrical storm(ES)characterized by refractoriness and recurrence.[1]For patients with implantable cardioverter defibrillator(ICD),the notion is redefined as no fewer than three appropriate and separate(at least 5 min for each interval)ICD interventions given within 24 h.

关键词： cardiac storm electrical

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HRT对硫自养反硝化脱氮性能及微生物群落结构的影响

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安徽化工 2024年第3期50卷 54-59页

作者：李政辉童洋洋施绪安徽工业大学能源与环境学院安徽马鞍山243002

为探究水力停留时间(HRT)对单质硫源驱动下硫自养反硝化系统的影响,构建了硫自养反硝化UASB反应器,研究不同HRT下单质硫自养反硝化系统脱氮性能,并从微生物群落结构的角度分析系统种间协同竞争作用。结果表明:①不同HRT,单质硫自养反硝... 详细信息

为探究水力停留时间(HRT)对单质硫源驱动下硫自养反硝化系统的影响,构建了硫自养反硝化UASB反应器,研究不同HRT下单质硫自养反硝化系统脱氮性能,并从微生物群落结构的角度分析系统种间协同竞争作用。结果表明:①不同HRT,单质硫自养反硝化系统脱氮性能存在差异,HRT下降到16 h后NO_(3)^(-)-N去除率从75%降低到20%;②HRT=48 h,出水SO_(4)^(2-)浓度低于理论值,发生硫酸盐还原反应;③Thiobacillus为反应器中的优势菌属,相对丰度达到26.3%,随HRT降低,反应器中脱氮微生物丰度降低,部分菌属丰度降低到0%;④硫酸盐还原菌在HRT=48 h大量富集,反应器内部存在硫循环过程。本实验为硫自养反硝化脱氮提供技术支持,对硝酸盐污染控制具有重要的指导价值。

关键词：硫自养反硝化水力停留时间微生物群落结构硫循环

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新型两性离子粘土稳定剂的制备及其性能研究

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应用化工 2024年第4期53卷 848-852,857页

作者：孟祖超李正辉马海瑞相杰王天文李莹莹西安石油大学化学化工学院陕西西安710065 西安石油大学油气田化学陕西省高校工程研究中心陕西西安710065 西安航天动力研究所陕西西安710100

以丙烯酰胺(AM)、二甲基二烯丙基氯化铵(DMDAAC)、2-丙烯酰胺基-2-甲基丙磺酸(AMPS)和N-乙烯基吡咯烷酮(NVP)为反应单体,以过硫酸胺、亚硫酸氢钠为引发剂,制备了一种新型的两性离子粘土稳定剂,并采用红外光谱对其结构进行了表征。结果表... 详细信息

以丙烯酰胺(AM)、二甲基二烯丙基氯化铵(DMDAAC)、2-丙烯酰胺基-2-甲基丙磺酸(AMPS)和N-乙烯基吡咯烷酮(NVP)为反应单体,以过硫酸胺、亚硫酸氢钠为引发剂,制备了一种新型的两性离子粘土稳定剂,并采用红外光谱对其结构进行了表征。结果表明,在40℃下,当引发剂加量为0.55%,AM∶AMPS∶DMDAAC∶NVP物质的量比为160∶20∶13∶2,反应时间为3 h时,所制备的四元共聚物AM/AMPS/DMDAAC/NVP防膨率可达90.74%,具有良好的耐温耐盐性及耐酸碱性能,可以有效防止粘土水化膨胀、分散运移,有利于降低采油成本,在油气田领域具有良好的应用潜力。

关键词：粘土稳定剂储层保护两性离子聚合物性能

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Situational continuity-based air combat autonomous maneuvering decision-making

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Defence Technology(防务技术) 2023年第11期29卷 66-79页

作者： Jian-dong Zhang Yi-fei Yu li-hui zheng Qi-ming Yang Guo-qing Shi Yong Wu School of Electronics and Information Northwestern Polytechnical UniversityXi'an710129China Military Representative Office of Haizhuang Wuhan Bureau in Luoyang Region 471000China

In order to improve the performance of UAV's autonomous maneuvering decision-making,this paper proposes a decision-making method based on situational *** algorithm in this paper designs a situation evaluation function with strong guidance,then trains the Long Short-Term Memory(LSTM)under the framework of Deep Q Network(DQN)for air combat maneuvering *** the continuity between adjacent situations,the method takes multiple consecutive situations as one input of the neural *** reflect the difference between adjacent situations,the method takes the difference of situation evaluation value as the reward of reinforcement *** different scenarios,the algorithm proposed in this paper is compared with the algorithm based on the Fully Neural Network(FNN)and the algorithm based on statistical principles *** results show that,compared with the FNN algorithm,the algorithm proposed in this paper is more accurate and *** with the algorithm based on the statistical principles,the decision-making of the algorithm proposed in this paper is more efficient and its real-time performance is better.

关键词： UAV Maneuvering decision-making Situational continuity Long short-term memory(LSTM) Deep Q network(DQN) Fully neural network(FNN)

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Experimental study on the degree and damage-control mechanisms of fuzzy-ball-induced damage in single and multi-layer commingled tight reservoirs

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Petroleum Science 2023年第6期20卷 3598-3609页

作者： Chinedu J.Okere James J.Sheng li-Kun Fan Xiao-Wei Huang li-hui zheng Pan-Feng Wei Bob L.Herd Department of Petroleum Engineering Texas Tech UniversityTXUSA College of Petroleum Engineering China University of Petroleum(Beijing)Beijing102249China China Changqing Oilfield Company CNPCXi'an710018ShaanxiChina Beijing lihuiLab Energy Technology Co. Ltd.Beijing102200China

Fuzzy-ball working fluids(FBWFs)have been successfully applied in different development phases of tight *** reports revealed that FBWFs satisfactorily met all the operational and reservoir damage control requirements during their ***,the damage-control mechanisms and degree of formation damage caused by fuzzy-ball fluids have not been investigated in lab-scale studies so *** this study,the degree of fuzzy-ball-induced damage in single-and double-layer reservoirs was evaluated through core flooding experiments that were based on permeability and flow rate ***,its damage mechanisms were observed via scanning electron microscope and energy-dispersive spectroscopy *** results show that:(1)For single-layer reservoirs,the FBWF induced weak damage on coals and medium-to-weak damage on sandstones,and the difference of the damage in permeability or flow rate index on coals and sandstones is below 1%.Moreover,the minimum permeability recovery rate was above 66%.(2)For double-layer commingled reservoirs,the flow rate index revealed weak damage and the overall damage in double-layer was lower than the single-layer reservoirs.(3)There is no significant alteration in the microscopic structure of fuzzy-ball saturated cores with no evidence of fines *** dissolution of lead and sulfur occurred in coal samples,while tellurium in sandstone,aluminum,and magnesium in ***,the precipitation of aluminum,magnesium,and sodium occurred in sandstone but no precipitates found in coal and *** temporal plugging and dispersion characteristics of the FBWFs enable the generation of reservoir protection layers that will minimize formation damage due to solid and fluid invasion.

关键词： Drilling Fracture Fuzzy-ball fluids Formation damage analysis Muti-layer tight reservoirs Permeability damage index Flow rate damage index

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Flurbiprofen microneedle patches for the management of acute postoperative pain

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Nano Research 2024年第8期17卷 7493-7503页

作者： Huaqing Chu Yanyan Zhang Yuan Yang Jiangtao Xue Cong li Wei Zhang Zhou li hui zheng National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases School of Integrated Chinese and Western MedicineHunan University of Chinese MedicineChangsha 410208China School of life Science Institute of Engineering MedicineBeijing Institute of TechnologyBeijing 100081China Institute of Process Engineering Chinese Academy of SciencesBeijing 100190China

Acute postoperative pain is commonly treated with flurbiprofen(FBP),but conventional delivery methods are *** study prepared a new non-burst release microneedles(MNs)using genipin cross-linked gelatin(cGel).By adding varying amounts of genipin to modulate the crosslinking degree of cGel,the drug release behavior of the drug-loaded MNs in the skin can be *** crosslinking parameters that meet therapeutic requirements are selected,thus providing rapid and longlasting analgesic *** solutions were successfully cross-linked,altering matrix material microstructure,confirmed by scanning electron microscope imaging and fourier transform infrared *** demonstrated increasing mechanical strength with higher *** release rates were rapid initially,then slowed,exhibiting a characteristic of decreased release rates with increasing degrees of *** vivo,FBP/cGel MNs significantly reduced allodynia and hyperalgesia post-surgery,with the greatest effect observed at 2–3 h post-surgery,and can maintain analgesia for up to 6 *** tests confirmed good ***/cGel MNs effectively penetrate the stratum corneum,safely delivering drugs with significant analgesic effects,excellent mechanical properties,and good biocompatibility,representing a promising strategy for managing acute postoperative pain.

关键词： microneedle postoperative pain flurbiprofen non-steroid anti-inflammatory drug cross-linked gelatin

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Full-Stokes metasurface polarimetry requiring only a single measurement

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Photonics Research 2024年第3期12卷 514-521页

作者： CHENGLONG zheng hui li JINGYU liU MENGGUANG WANG HUAPING ZANG YAN ZHANG JIANQUAN YAO Key Laboratory of Material Physics Ministry of EducationSchool of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China Key Laboratory of Opto-Electronics Information Technology(Tianjin University) Ministry of EducationSchool of Precision Instruments and Opto-Electronics EngineeringTianjin UniversityTianjin 300072China Beijing Key Laboratory for Metamaterials and Devices Key Laboratory of Terahertz OptoelectronicsMinistry of Educationand Beijing Advanced Innovation Center for Imaging TechnologyDepartment of PhysicsCapital Normal UniversityBeijing 100048China State Key Laboratory of Modern Optical Instrumentation College of Optical Science and EngineeringZhejiang UniversityHangzhou 310027China

Polarization is crucial in various fields such as imaging,sensing,and substance detection.A compact,fast,and accurate polarization detection device is vital for these ***,we demonstrate a multifocus metalens for terahertz polarization detection that requires only a single measurement to obtain complete polarization parameters and reconstruct the polarization state of the incident *** individual subarrays of this metalens convert each of the six polarized components into the same polarization,which in turn links the Stokes parameters to these six *** incident linear polarizations and elliptical polarizations are characterized by Stokes parameters and polarization *** and experimental results show that the scheme can accurately detect the incident polarization with a single *** proposed metasurface polarimetry may find applications in the fields of real-time terahertz detection and integrated optics.

关键词： field incident polar

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Enhancing thermodynamic stability of single-crystal Ni-rich cathode material via a synergistic dual-substitution strategy

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Journal of Energy Chemistry 2024年第1期88卷 428-436,I0010页

作者： Jixue Shen hui li Haoyu Qi Zhan lin Zeheng li Chuanbo zheng Weitong Du Hao Chen Shanqing Zhang School of Metallurgy Engineering Jiangsu University of Science and TechnologyZhangjiagang 215600JiangsuChina School of Metallurgy and Environment Central South UniversityChangsha 410083HunanChina Guangdong Laboratory of Chemistry and Fine Chemical Industry Jieyang Center Jieyang 515200GuangdongChina Institute of Sustainable Transformation School of Chemical Engineering and Light IndustryGuangdong University of TechnologyGuangzhou 510006GuangdongChina Zhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture Technology College of Chemical and Biological EngineeringZhejiang UniversityHangzhou 310027ZhejiangChina Centre for Catalysis and Clean Energy School of Environment and ScienceGold Coast CampusGriffith UniversityGold Coast 4222QueenslandAustralia

Nickel(Ni)-rich cathode materials have become promising candidates for the next-generation electrical vehicles due to their high specific ***,the poor thermodynamic stability(including cyclic performance and safety performance or thermal stability)will restrain their wide commercial ***,a single-crystal Ni-rich li Ni_(0.83)Co_(0.12)Mn_(0.05)O_(2) cathode material is synthesized and modified by a dual-substitution strategy in which the high-valence doping element improves the structural stability by forming strong metal–oxygen binding forces,while the low-valence doping element eliminates high li^(+)/Ni^(2+)*** a result,this synergistic dual substitution can effectively suppress H2-H3 phase transition and generation of microcracks,thereby ultimately improving the thermodynamic stability of Ni-rich cathode ***,the dual-doped Ni-rich cathode delivers an extremely high capacity retention of 81%after 250 cycles(***/li+)in coin-type half cells and 87%after 1000 cycles(***/li^(+))in pouch-type full cells at a high temperature of 55℃.More impressively,the dual-doped sample exhibits excellent thermal stability,which demonstrates a higher thermal runaway temperature and a lower calorific *** synergetic effects of this dual-substitution strategy pave a new pathway for addressing the critical challenges of Ni-rich cathode at high temperatures,which will significantly advance the high-energy-density and high-safety cathodes to the subsequent commercialization.

关键词： Ni-rich cathode Single crystalline Dual-substitution strategy High-temperature cathode li-ion batteries

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Numerical and experimental study on the falling film flow characteristics with the effect of co-current gas flow in hydrogen liquefaction process

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Petroleum Science 2024年第2期21卷 1369-1384页

作者： Chong-zheng Sun Yu-Xing li hui Han Xiao-Yi Geng Xiao Lu College of Energy Storage Technology Shandong University of Science and TechnologyQingdao 266590ShandongChina College of Pipeline and Civil Engineering/Shandong Provincial Key Laboratory of Oil&Gas Storage and Transportation Safety China University of PetroleumQingdao 266580ShandongChina

liquid hydrogen storage and transportation is an effective method for large-scale transportation and utilization of hydrogen energy. Revealing the flow mechanism of cryogenic working fluid is the key to optimize heat exchanger structure and hydrogen liquefaction process(LH2). The methods of cryogenic visualization experiment, theoretical analysis and numerical simulation are conducted to study the falling film flow characteristics with the effect of co-current gas flow in LH2spiral wound heat *** results show that the flow rate of mixed refrigerant has a great influence on liquid film spreading process, falling film flow pattern and heat transfer performance. The liquid film of LH2mixed refrigerant with column flow pattern can not uniformly and completely cover the tube wall surface. As liquid flow rate increases, the falling film flow pattern evolves into sheet-column flow and sheet flow, and liquid film completely covers the surface of tube wall. With the increase of shear effect of gas-phase mixed refrigerant in the same direction, the liquid film gradually becomes unstable, and the flow pattern eventually evolves into a mist flow.

关键词： Hydrogen liquefaction Spiral wound heat exchanger Flow pattern transition Falling film flow

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