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Manipulating the Macroscopic and Microscopic Morphology of Large-Area Gravure-Printed ZnO Films for High-Performance Flexible Organic Solar Cells

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Energy & Environmental Materials 2024年第2期7卷 229-239页

作者： Zhenguo Wang jingbo Guo Yaqin Pan jin Fang Chao Gong lixin Mo qun Luo Jian lin Changqi Ma School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefei 230026China i-Lab&Printable Electronics Research Center Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of Sciences(CAS)Suzhou 215123China Beijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic CommunicationBeijing 102600China Jiangxi Institute of Nanotechnology Chinese Academy of Sciences(CAS)Nanchang 330200China

Gravure printing is a promising large-scale fabrication method for flexible organic solar cells(FOSCs)because it is compatible with two-dimension patternable roll-to-roll ***,the unsuitable rheological property of ZnO nanoinks resulted in unevenness and looseness of the gravure-printed ZnO interfacial *** we propose a strategy to manipulate the macroscopic and microscopic of the gravure-printed ZnO films through using mixed solvent and poly(vinylpyrrolidone)(PVP)*** regulation of drying speed effectively manipulates the droplets fusion and leveling process and eliminates the printing ribbing structure in the macroscopic *** additive of PVP effectively regulates the rheological property and improves the microscopic compactness of the *** this method,large-area ZnO∶PVP films(28×9 cm^(2))with excellent uniformity,compactness,conductivity,and bending durability were *** power conversion efficiencies of FOSCs with gravure-printed AgNWs and ZnO∶PVP films reached 14.34%and 17.07%for the 1 cm^(2)PM6:Y6 and PM6∶L8-BO flexible *** efficiency of 17.07%is the highest value to date for the 1 cm^(2)*** use of mixed solvent and PVP addition also significantly enlarged the printing window of ZnO ink,ensuring high-quality printed thin films with thicknesses varying from 30 to 100 nm.

关键词： flexible organic solar cell gravure printing large-area flexible interfacial layer rheology properties zinc oxide

Video caching and scheduling with edge cooperation

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Digital Communications and Networks 2024年第2期10卷 450-460页

作者： Zhidu li Fuxiang li Tong Tang Hong Zhang jin Yang School of Communication and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing400065China Advanced Network and Intelligent Connection Technology Key Laboratory of Chongqing Education Commission of China Chongqing400065China Key Laboratory of Ubiquitous Sensing and Networking in Chongqing Chongqing400065China

In this paper,we explore a distributed collaborative caching and computing model to support the distribution of adaptive bit rate video *** aim is to reduce the average initial buffer delay and improve the quality of user *** the difference between global and local video popularities and the time-varying characteristics of video popularity,a two-stage caching scheme is proposed to push popular videos closer to users and minimize the average initial buffer *** on both long-term content popularity and short-term content popularity,the proposed caching solution is decouple into the proactive cache stage and the cache update *** the proactive cache stage,we develop a proactive cache placement algorithm that can be executed in an off-peak *** the cache update stage,we propose a reactive cache update algorithm to update the existing cache policy to minimize the buffer *** results verify that the proposed caching algorithms can reduce the initial buffer delay efficiently.

关键词： Video service Distributed and collaborative caching Long-term popularity Short-term popularity

In silico off-target profiling for enhanced drug safety assessment

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Acta Pharmaceutica Sinica B 2024年第7期14卷 2927-2941页

作者： jin liu Yike Gui jingxin Rao jingjing Sun Gang Wang qun Ren Ning Qu Buying Niu Zhiyi Chene Xia Sheng Yitian Wang Mingyue Zheng Xutong li College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China Drug Discovery and Design Center State Key Laboratory of Drug ResearchShanghai Institute of Materia Medica Chinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China Nanjing University of Chinese Medicine Nanjing 210023China School of Pharmaceutical Science and Technology Hangzhou Institute for Advanced StudyHangzhou 330106China

Ensuring drug safety in the early stages of drug development is crucial to avoid costly failures in subsequent ***,the economic burden associated with detecting drug off-targets and potential side effects through in vitro safety screening and animal testing is *** off-target interactions,along with the adverse drug reactions they induce,are significant factors affecting drug *** assess the liability of candidate drugs,we developed an artificial intelligence model for the precise prediction of compound off-target interactions,leveraging multi-task graph neural *** outcomes of off-target predictions can serve as representations for compounds,enabling the differentiation of drugs under various ATC codes and the classification of compound ***,the predicted off-target profiles are employed in adverse drug reaction(ADR)enrichment analysis,facilitating the inference of potential ADRs for a *** the withdrawn drug Pergolide as an example,we elucidate the mechanisms underlying ADRs at the target level,contributing to the exploration of the potential clinical relevance of newly predicted off-target ***,our work facilitates the early assessment of compound safety/toxicity based on off-target identification,deduces potential ADRs of drugs,and ultimately promotes the secure development of drugs.

关键词： Drug safety Off-target prediction Adverse drug reactions Toxicity Molecular representation Artificial intelligence

Genome sequencing provides insights into Caprifoliaceae genome evolution and the mechanism underlying second blooming phenomenon in Heptacodium miconioides

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Horticultural Plant Journal 2024年第3期10卷 897-910页

作者： Yueling li Zhongshuai Sun Zexin jin Junmin li Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation Taizhou UniversityTaizhouZhejiang 318000China Institute of Ecology Taizhou UniversityTaizhouZhejiang 318000China School of life Sciences Taizhou UniversityTaizhouZhejiang 318000China

Plants of the Caprifoliaceae family are widely cultivated worldwide as ornamental plants owing to their numerous,sweet-smelling,beautiful flowers and *** miconioides Rehd.,a member of the family,is endemic to eastern China and is cultivated as a popular ornamental plant in North America and European *** has a rather novel and beautiful trait of high horticultural value,that is,its sepals persist and enlarge,turning purplish ***,we report the chromosome-level genome assembly of *** to understand its evolution and floral *** 622.28 Mb assembled genome harbored a shared whole-genome duplication with a related species,Lonicera *** genomic analysis suggested that chromosome fission events following genome duplication underlie the unusual chromosome number of these two species,as well as chromosome fission of another five chromosomes in ***,giving rise to a haploid chromosome number of 14(versus 9 in ***).In addition,based on transcriptome and chloroplast genome analysis of 17 representative species in the Caprifoliaceae,we assumed that large structural variations in the chromosomes of *** were not caused by *** in the candidate genes of the MADS-box family were detected in the *** genome,including AP1-,AP3-,and SEPexpanded,which might underlie the sepal elongation and development in this *** current findings provided a critical resource for genome evolution studies in Caprifoliaceae and it was an example of how multi-omics data can elucidate the regulation of important ornamental traits.

关键词： Heptacodium miconioides Genome assembly Caprifoliaceae Chromosome fusion Sepal traits

Adaptive Bistable Stochastic Resonance Based Weak Signal Reception in Additive Laplacian Noise

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China Communications 2024年第1期21卷 228-241页

作者： jin liu Zan li Qiguang Miao li Yang School of Computer Science and Technology Xidian UniversityXi’an 710071China State Key Laboratory of Integrated Services Networks Xidian UniversityXi’an 710071China

Weak signal reception is a very important and challenging problem for communication systems especially in the presence of non-Gaussian noise,and in which case the performance of optimal linear correlated receiver degrades *** at this,a novel uncorrelated reception scheme based on adaptive bistable stochastic resonance(ABSR)for a weak signal in additive Laplacian noise is *** analyzing the key issue that the quantitative cooperative resonance matching relationship between the characteristics of the noisy signal and the nonlinear bistable system,an analytical expression of the bistable system parameters is *** this basis,by means of bistable system parameters self-adaptive adjustment,the counterintuitive stochastic resonance(SR)phenomenon can be easily generated at which the random noise is changed into a benefit to assist signal ***,it is demonstrated that approximately 8dB bit error ratio(BER)performance improvement for the ABSR-based uncorrelated receiver when compared with the traditional uncorrelated receiver at low signal to noise ratio(SNR)conditions varying from-30dB to-5dB.

关键词： adaptive bistable stochastic resonance additive Laplacian noise low signal to noise ratio uncorrelated reception scheme weak signal reception

Identification of reservoir types in deep carbonates based on mixedkernel machine learning using geophysical logging data

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Petroleum Science 2024年第3期21卷 1632-1648页

作者： jin-Xiong Shi Xiang-Yuan Zhao lian-Bo Zeng Yun-Zhao Zhang Zheng-Ping Zhu Shao-qun Dong Key Laboratory of Exploration Technologies for Oil and Gas Resources of the Ministry of Education Yangtze UniversityWuhan4310HubeiChina School of Geosciences Yangtze UniversityWuhan430100HubeiChina College of Geosciences China University of Petroleum(Beijing)Beijing102249China Petroleum Exploration and Production Research Institute of SINOPEC Beijing100083China School of Earth Sciences and Engineering Xi'an Shiyou UniversityXi'an 710065ShaanxiChina

Identification of reservoir types in deep carbonates has always been a great challenge due to complex logging responses caused by the heterogeneous scale and distribution of storage *** cross-plot analysis and empirical formula methods for identifying reservoir types using geophysical logging data have high uncertainty and low efficiency,which cannot accurately reflect the nonlinear relationship between reservoir types and logging ***,the kernel Fisher discriminant analysis(KFD),a kernel-based machine learning technique,attracts attention in many fields because of its strong nonlinear processing ***,the overall performance of KFD model may be limited as a single kernel function cannot simultaneously extrapolate and interpolate well,especially for highly complex data *** address this issue,in this study,a mixed kernel Fisher discriminant analysis(MKFD)model was established and applied to identify reservoir types of the deep Sinian carbonates in central Sichuan Basin,*** MKFD model was trained and tested with 453 datasets from 7 coring wells,utilizing GR,CAL,DEN,AC,CNL and RT logs as input *** particle swarm optimization(PSO)was adopted for hyper-parameter optimization of MKFD *** evaluate the model performance,prediction results of MKFD were compared with those of basic-kernel based KFD,RF and SVM ***,the built MKFD model was applied in a blind well test,and a variable importance analysis was *** comparison and blind test results demonstrated that MKFD outperformed traditional KFD,RF and SVM in the identification of reservoir types,which provided higher accuracy and stronger *** MKFD can therefore be a reliable method for identifying reservoir types of deep carbonates.

关键词： Reservoir type identification Geophysical logging data Kernel Fisher discriminantanalysis Mixedkernel function Deep carbonates

Regulating metal-acid double site balance on mesoporous SiO2-Al2O3 composite oxide for supercritical n-decane cracking

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Petroleum Science 2024年第4期21卷 2881-2891页

作者： liu-ling Chen Jun Zhang Chun-Guang li li-qun Fei Bo Wang Chen-Qi Zhang Yi Jiao Jian-li Wang Institute of New Energy and Low-Carbon Technology Sichuan University Engineering Research Center of Combustion and Cooling for Aerospace Power Ministry of Education School of Chemical Engineering Sichuan University State Key Laboratory of Industrial Vent Gas Reuse Southwest Institute of Chemical Co. Ltd Science and Technology on Scramjet Laboratory Beijing Power Machinery Research Institute

The balance between metal and acid sites directly affects the preparation of high-performance cracking catalysts with high heat sink and low ***,how to control acid-metal sites balance and its relationship with cracking performance are reported *** this work,a series of Pt/Al2O3-SiO2dual sites catalysts with different metal to acid active sites ratio(CM/CSA) were constructed by ethanolassisted impregnation method and the impact on n-decane cracking under supercritical conditions was systematically and deeply *** results showed that the conversion and carbon deposition increased gradually with varied CM/CSAand reached the balance at CM/CSAof *** proper ratio CM/CSA（0.13） can balance the deep dehydrogenation coking over metal active sites and high heat sink of cracking over acid active sites,the chemical heat sink reaches amazing 1.75 MJ/kg and carbon deposition is only22.03 mg/cm2at 750℃.Meanwhile,the few metal sites at low CM/CSAand the few strong acid sites at high CM/CSAare the main factors limiting the cracking *** CM/CSAlimit the activation of C-H bond and deep dehydrogenation of coking precursor,resulting in relative low cracking activity and carbon deposition,while high CM/CSAlimit the activation of C-C bond and increase the deep *** this contribution,design and construction of metal-acid dual sites can not only provide the technical solution for the preparation of high heat sink and low coking cracking catalyst,but also deepen the understanding of the cracking path of hydrocarbon fuel.

关键词： Metal-acid dual sites balance Catalytic cracking Hydrocarbon fuels Chemical heat sink Carbon deposition

Nicotinamide adenine dinucleotide treatment confers resistance to neonatal ischemia and hypoxia:effects on neurobehavioral phenotypes

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Neural Regeneration Research 2024年第12期19卷 2760-2772页

作者： Xiaowen Xu Xinxin Wang li Zhang Yiming jin lili li Meifang jin lianyong li Hong Ni Division of Brain Science Institute of Pediatric ResearchChildren’s Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Department of Pediatric Orthopedics Shengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

Neonatal hypoxic-ischemic brain injury is the main cause of hypoxic-ischemic encephalopathy and cerebral ***,there are few effective clinical treatments for neonatal hypoxic-ischemic brain ***,we investigated the neuroprotective and molecular mechanisms of exogenous nicotinamide adenine dinucleotide,which can protect against hypoxic injury in adulthood,in a mouse model of neonatal hypoxic-ischemic brain *** this study,nicotinamide adenine dinucleotide(5 mg/kg)was intraperitoneally administered 30 minutes befo re surgery and every 24 hours *** results showed that nicotinamide adenine dinucleotide treatment improved body weight,brain structure,adenosine triphosphate levels,oxidative damage,neurobehavioral test outcomes,and seizure threshold in experimental *** mass tag proteomics revealed that numerous proteins were altered after nicotinamide adenine dinucleotide treatment in hypoxic-ischemic brain injury *** reaction monitoring and western blotting confirmed changes in the expression levels of proteins including serine(or cysteine)peptidase inhibitor,clade A,member 3N,fibronectin 1,5'-nucleotidase,cytosolic IA,microtubule associated protein 2,and complexin *** analyses showed that nicotinamide adenine dinucleotide ameliorated hypoxic-ischemic injury through inflammation-related signaling pathways(e.g.,nuclear factor-kappa B,mitogen-activated protein kinase,and phosphatidylinositol 3 kinase/protein kinase B).These findings suggest that nicotinamide adenine dinucleotide treatment can improve neurobehavioral phenotypes in hypoxic-ischemic brain injury mice through inflammation-related pathways.

关键词： brain injury cerebral palsy hypoxia hypoxic-ischemic brain injury inflammation neuroprotection nicotinamide adenine dinucleotide neonate nicotinamide adenine dinucleotide proteomics

Flocking of a Cucker–Smale Type Model with Compactly Supported Interaction Functions

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2285-2296页

作者： Chun Yin jin Shuang Zhi li College of Science China Agricultural UniversityBeijing 100083P.R.China

How to analyze flocking behaviors of a multi-agent system with local interaction functions is a challenging problem in *** and Tadmor in 2011 also stressed the significance to assume that the interaction function is rapidly decaying or cut-off at a finite distance(*** and Tadmor in ***.2011).In this paper,we study the flocking behavior of a Cucker–Smale type model with compactly supported interaction *** properties of a connected stochastic matrix,together with an elaborate analysis on perturbations of a linearized system,we obtain a sufficient condition imposed only on model parameters and initial data to guarantee ***,it is shown that the system achieves flocking at an exponential rate.

关键词： Cucker-Smale model local interaction flocking stochastic matrix neighbor graph