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Detection and interpretation of the time-varying seasonal signals in China with multi-geodetic measurements

Geodesy and Geodynamics 2025年第1期16卷 42-54页

作者： liansheng Deng Yugang Xiao Qusen Chen Wei peng Zhao li Hua Chen Zhiwen Wu School of Electrical and Electronic Information Engineering Hubei Polytechnic University Hubei Luojia Laboratory GNSS Research Center Wuhan University Changjiang Spatial Information Technology Engineering Co. Ltd. Key Laboratory of Spatial Data Mining & Information Sharing of the Ministry of Education Fuzhou University School of Geodesy and Geomatics Wuhan University The First Surveying and Mapping Institute of Hunan Province

The time-varying periodic variations in Global Navigation Satellite System(GNSS) stations affect the reliable time series analysis and appropriate geophysical interpretation. In this study, we apply the singular spectrum analysis(SSA) method to characterize and interpret the periodic patterns of GNSS deformations in China using multiple geodetic datasets. These include 23-year observations from the Crustal Movement Observation Network of China(CMONOC), displacements inferred from the Gravity Recovery and Climate Experiment(GRACE), and loadings derived from Geophysical models(GM). The results reveal that all CMONOC time series exhibit seasonal signals characterized by amplitude and phase modulations, and the SSA method outperforms the traditional least squares fitting(LSF) method in extracting and interpreting the time-varying seasonal signals from the original time series. The decrease in the root mean square(RMS) correlates well with the annual cycle variance estimated by the SSA method, and the average reduction in noise amplitudes is nearly twice as much for SSA filtered results compared with those from the LSF method. With SSA analysis,the time-varying seasonal signals for all the selected stations can be identified in the reconstructed components corresponding to the first ten eigenvalues. Moreover, both RMS reduction and correlation analysis imply the advantages of GRACE solutions in explaining the GNSS periodic variations,and the geophysical effects can account for 71% of the GNSS annual amplitudes, and the average RMS reduction is 15%. The SSA method has proved to be useful for investigating the GNSS timevarying seasonal signals. It could be applicable as an auxiliary tool in the improvement of nonlinear variations investigations.

关键词： GNSS coordinate time series Singular spectrum analysis Time-varying seasonal signals Loading effects GRACE

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Predicting Diabetic Retinopathy Using a Machine Learning Approach Informed by Whole-Exome Sequencing Studies

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Biomedical and Environmental Sciences 2025年第1期38卷 67-78页

作者： Chongyang She Wenying fan Yunyun li Yong Tao Zufei li Department of Ophthalmology Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China Beijing Tongren Eye Center Beijing Tongren HospitalCapital Medical UniversityBeijing 100176China Department of Otorhinolaryngology Head and Neck SurgeryBeijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China

Objective To establish and validate a novel diabetic retinopathy(DR)risk-prediction model using a whole-exome sequencing(WES)-based machine learning(ML)*** WES was performed to identify potential single nucleotide polymorphism(SNP)or mutation sites in a DR pedigree comprising 10 members.A prediction model was established and validated in a cohort of 420 type 2 diabetic patients based on both genetic and demographic *** contribution of each feature was assessed using Shapley Additive explanation *** efficacies of the models with and without SNP were *** WES revealed that seven SNPs/mutations(rs116911833 in TRIM7,1997T>C in LRBA,1643T>C in PRMT10,rs117858678 in C9orf152,rs201922794 in CLDN25,rs146694895 in SH3GLB2,and rs201407189 in fanCC)were associated with ***,the model including rs146694895 and rs201407189 achieved better performance in predicting DR(accuracy:80.2%;sensitivity:83.3%;specificity:76.7%;area under the receiver operating characteristic curve[AUC]:80.0%)than the model without these SNPs(accuracy:79.4%;sensitivity:80.3%;specificity:78.3%;AUC:79.3%).Conclusion Novel SNP sites associated with DR were identified in the DR *** of rs146694895 and rs201407189 significantly enhanced the performance of the ML-based DR prediction model.

关键词： Machine learning Diabetic retinopathy Whole exome sequencing Type 2 diabetes mellitus

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Enhancing angiogenesis and osseointegration through a double gyroid Ti6Al4V scaffold with triply periodic minimal surface

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Bio-Design and Manufacturing 2025年第1期8卷 36-54,I0013-I0017页

作者： Hao liu Hao Chen Bin Sun Danyang fan Aobo Zhang Hanqiang liu Hexiang Wei Wenbo Yang Yongyue li peng Xia Qing Han Jincheng Wang Department of Orthopedic Surgery The Second Hospital of Jilin UniversityChangchun 130000China Department of Dermatology The Second Hospital of Jilin UniversityChangchun 130000China

The pore structure of porous scaffolds plays a crucial role in bone *** prevalent bone implant structure in clinical practice is the traditional cubic ***,the traditional cubic structure exhibits sharp edges and junctions that are not conducive to cell adhesion or *** this study,a double gyroid(DG)Ti6Al4V scaffold based on a triply periodic minimal surface(TPMS)structure was devised,and the osseointegration performance of DG structural scaffolds with varying porosities was *** tests revealed that the elastic modulus and compressive strength of DG structural scaffolds were sufficient for orthopedic *** vitro cellular experiments demonstrated that the DG structure significantly enhanced cell proliferation,vascularization,and osteogenic differentiation compared to the cubic *** DG structure with 55%porosity exhibited the most favorable *** vivo experiments in rabbits further demonstrated that DG scaffolds could promote neovascularization and bone regeneration and maturation;those with 55%porosity performed *** the surface area,specific surface area per unit volume,and internal flow distribution characteristics of gyroid and DG structure scaffolds,the latter are more conducive to cell adhesion and growth within *** study underscored the potential of DG scaffolds based on the TPMS structure in optimizing the pore structure design of titanium scaffolds,inducing angiogenesis,and advancing the clinical application of titanium scaffolds for repairing bone defects.

关键词： Double gyroid Triply periodic minimal surface Osseointegration Angiogenesis

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Fast and robust production of quantum superposition states by the fractional shortcut to adiabaticity

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Communications in Theoretical Physics 2025年第1期77卷 54-64页

作者： Guan-Qiang li Hao Guo Yu-Qi Zhang Bo Yang Ping peng Department of Physics and Institute of Theoretical Physics Shaanxi University of Science and TechnologyXi'an 710021China

The fractional shortcut to adiabaticity(f-STA)for the production of quantum superposition states is proposed firstly via a three-level system with aΛ-type linkage pattern and a four-level system with a tripod *** fast and robust production of the coherent superposition states is studied by comparing the populations for the f-STA and the fractional stimulated Raman adiabatic passage(f-STIRAP).The states with equal proportions can be produced by fixing the controllable parameters of the driving pulses at the final moment of the whole *** effects of the pulse intensity and the time delay of the pulses on the production process are discussed by monitoring the populations on all of the quantum *** particular,the spontaneous emission arising from the intermediate state is investigated by the quantum master *** result reveals that the f-STA exhibits superior advantages over the f-STIRAP in producing the superposition states.

关键词： quantum population transfer shortcut to adiabaticity coherent superposition states dark states spontaneous emission

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Responses of Soybean GmSARK Gene to Environmental Stresses

Responses of Soybean GmSARK Gene to Environmental Stresses

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2007中国植物生理学会全国学术会议

作者： peng-li li fan Xu Dong liu Ning Ning Wang (Department of Plant Biology and Ecology,Nankai University,Tianjin 300071,China)

＜正＞Leaf senescence is a form of programmed cell *** in gene expression and signalling pathways between developmental and stress-induced senescence in higher plants have been largely reported. We have previously described a soybean LRR-RLK gene,GmSARK,which plays an important role in regulation of soybean leaf *** also found that over-expression of GmSARK gene greatly

关键词： Soybean GrnSARK RLK Senescence Environmental Stress

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Environment-friendly Ca2+/Cr3+co-doping LaAlO3 ceramics with excellent infrared radiation performance for energy-saving

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JOURNAL OF ADVANCED CERAMICS 2025年第1期14卷 205-214页

作者： Yuan, Xinglai Wang, Qinghu Wu, Runke Sang, Shaobai Xu, Yibiao liang, Xiong Pan, liping fan, Bingbing li, Yawei Zhang, Rui li, Jiangtao Volkova, Olena Wuhan Univ Sci & Technol State Key Lab Refractories & Met Joint Int Res Lab Refractories & Met Wuhan 430081 Peoples R China Zhengzhou Univ Sch Mat Sci & Engn Zhengzhou 450001 Peoples R China Henan Acad Sci Inst Adv Ceram Zhengzhou 450046 Peoples R China Chinese Acad Sci Tech Inst Phys & Chem Beijing 100190 Peoples R China TU Bergakad Freiberg Inst Iron & Steel Technol D-09599 Freiberg Germany

Ca2+/Cr3+ co-doped LaAlO3 infrared (IR) ceramics have been proven to be potential energy-saving materials for high- temperature industries because of their high emissivity and high- temperature stability. However, Cr6+ formation commonly occurs in materials and poses environmental and health risks, such as Cr6+ dissolution in water and CrO3(g) volatilization. In this study, we combined high emissivity with in situ detoxification by introducing residual Al2O3 into Ca2+/Cr3+ co-doped LaAlO3 ceramics. Compared with the undoped ceramics, the addition of 20 wt% residual Al2O3 resulted in a 78.5% reduction to 18.44 mg/kg (lower than the EU standard of 20 mg/kg) in Cr6+ dissolution and a decrease in 77.8% CrO3(g) volatilization. This significant detoxification effect can be attributed to the formation of CaAl12-xCrxO19. Additionally, as the residual Al2O3 content increased from 5 to 20 wt%, the ceramics maintained high emissivity, above 0.896 in the near-infrared band and 0.781 in the mid-infrared band. Furthermore, the IR coating effectively increased the surface temperature (from 767.1 to 790.7 degrees C/min) and the heat radiation of the heating source, increasing the heating rate from 31.7 to 34.6 degrees C/min during water heating. This work offers a promising approach for designing environmentally friendly IR ceramics with excellent IR performance for energy-saving applications in the high-temperature industry.

关键词： infrared (IR) radiation energy-saving environmentally friendly Cr6+suppression LaAlO3

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Changes in River Cross-section Morphology and Response to Streamflow and Sediment Processes in Middle Reaches of Yellow River,China

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Chinese Geographical Science 2025年第1期35卷 161-174页

作者： WEN Yongfu li pengfei li Mengzhen MA Chaohui GAO peng MU Xingmin ZHAO Guangju The Research Center of Soil and Water Conservation and Ecological Environment Chinese Academy of Sciences and Ministry of EducationYangling 712100China Institute of Soil and Water Conservation Chinese Academy of Sciences&Ministry of Water ResourcesYangling 712100China University of Chinese Academy of Sciences Beijing 100049China Hebei University of Water Resources and Electric Engineering Cangzhou 061001China Xi’an University of Science and Technology Xi’an 710054China Institute of Soil and Water Conservation Northwest A&F UniversityYangling 712100China

Changes in river cross-section morphology have decisive influences on the flood discharge and sand transport capacity of rivers;thus,these changes strongly reflect the vitality of a *** this paper,based on the river cross-section and water and sediment data of two different periods(1974−1987 and 2007−2021),the trend analysis,change-point analysis and sediment rating curve method were used to analyze the change process of river cross-section morphology and its response to streamflow and sediment changes in the main river stream of the Yellow River at the Longmen hydrological *** 1974 to 1987(except in 1977),the riverbed experi-enced siltation,and the riverbed elevation ***,from 2007 to 2021,the riverbed experienced scouring,and the riverbed el-evation gradually *** cross-section shape changed from rectangular to U-shaped(deeper on the right side)at the Longmen *** changes in streamflow and sediment processes significantly impacted the evolution of river ***-flow(Pline in riverbed elevation at the Longmen cross-section from 2007 to *** findings help us better understand the impacts of ecological restoration on changes in river streamflow and sediment during river evolution.

关键词： cross-section shape riverbed elevation water depth streamflow sediment discharge eco-restoration Longmen station middle reaches of the Yellow River,China

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Passive Integrated Sensing and Communication Scheme Based on RF Fingerprint Information Extraction for Cell-Free RAN

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China Communications 2025年第1期22卷 171-181页

作者： Yu Jingxuan Zeng fan li Jiamin liu Feiyang Zhu pengcheng Wang Dongming You Xiaohu National Mobile Communications Research Laboratory School of Information Science and EngineeringSoutheast UniversityNanjing 210096China Purple Mountain Laboratories Nanjing 211111China 54th Research Institute of Electronics Technology Group Corporation Shijiazhuang 050081China

This paper investigates how to achieve integrated sensing and communication(ISAC)based on a cell-free radio access network(CF-RAN)architecture with a minimum footprint of communication *** propose a new passive sensing *** scheme is based on the radio frequency(RF)fingerprint learning of the RF radio unit(RRU)to build an RF fingerprint library of *** source RRU is identified by comparing the RF fingerprints carried by the signal at the receiver *** receiver extracts the channel parameters from the signal and estimates the channel environment,thus locating the reflectors in the *** proposed scheme can effectively solve the problem of interference between signals in the same time-frequency domain but in different spatial domains when multiple RRUs jointly serve users in CF-RAN *** results show that the proposed passive ISAC scheme can effectively detect reflector location information in the environment without degrading the communication performance.

关键词： CF-RAN ISAC passive sensing RF fingerprinting

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Clinical observation of contralateral needling combined with Maitland joint mobilization for chronic ankle sprain

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Journal of Acupuncture and Tuina Science 2025年第1期23卷 89-94页

作者： li Yu WU Zhenying fan peng Qinhuangdao Hospital of Traditional Chinese Medicine Hebei ProvinceQinhuangdao 066000China

Objective:To observe the effect of contralateral needling to regulate tendons and circulate Qi combined with Maitland joint mobilization on ankle joint function and the peri-ankle muscle groups in patients with chronic ankle ***:A total of 77 patients with chronic ankle sprain,meeting the inclusion criteria,were randomly divided into a control group(38 cases)and an observation group(39 cases).The control group received conventional acupuncture treatment,while the observation group received contralateral needling to regulate tendons and circulate Qi combined with joint *** groups were treated once daily for two consecutive *** American Orthopaedic Foot&Ankle Society(AOFAS)ankle-hindfoot scale was used to assess ankle joint function in the two groups,and the biomechanical model of skeletal muscles of lower limbs(Gait2392_simbody)was used to evaluate the muscle strength of the peri-ankle muscle ***:The total effective rate in the observation group was 94.9%,significantly higher than the 79.0%in the control group(Plis posterior,and flexor hallucis longus in both groups increased compared to their respective pre-treatment values(Plis anterior in both groups increased compared t

关键词： Acupuncture Therapy Contralateral Needling Pain Measurement Visual Analog Scale Muscle Strength Ankle Injuries Sprains and Strain

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Long-read sequencing reveals novel genetic polymorphisms in the major histocompatibility complex region and their impacts on the Han Chinese population

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Science China life Sciences 2025年

作者： Cong Zhou Tingting Gong Shuhang li li Jin Shaohua fan State Key Laboratory of Genetic Engineering Lab for Evolutionary Synthesis School of Life Sciences Human Phenome Institute Fudan University Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058) Chinese Academy of Medical Sciences

Human leukocyte antigen(HLA) genes in the major histocompatibility complex(MHC) region are crucial for immunity and are associated with numerous diseases and phenotypes. The MHC region's complexity and high genetic diversity make it challenging to analyze using short-read sequencing(SRS) technology. We sequence the MHC region of 100 Han Chinese individuals using both long-read sequencing(LRS) and SRS platforms at approximately 30X coverage to study genetic alterations and their potential functional impacts. LRS provides significantly greater coverage of the MHC region and eight classical HLA genes, particularly at the HLA-DRB1 locus, compared with SRS. We detect 78,249 single nucleotide polymorphisms(SNPs) using LRS, with 26.0% undetectable by SRS. Based on SNP and inferred HLA allele types, we construct an LRS-based MHC reference panel for the Han Chinese, containing approximately 2.6 times more genetic variants than the SRS-based Han-MHC reference panel. A phenome-wide association study assessing 26,024 phenotypes across 15 categories identifies significant associations for 7,879 independent variants(including 809 LRS-specific SNPs) with 409 phenotypes in nine categories. This analysis reveals 24 unreported HLA allele associations in the bioelectric and cellular categories. The conditional analysis identifies 530independent signals across the 409 phenotypes, including 28 previously unreported signals of eight classical HLA genes associated with 33phenotypes. Of the top-associated SNPs, 191 are detected by LRS only. Fine-mapping identifies 126 independent candidate causal SNPs for three immune-related cellular phenotypes, with 17 detected exclusively by LRS. Our study reveals previously unreported variants and their functional impacts in the MHC region, enhancing our understanding of genetic diversity and its potential biological implications in the Han Chinese population.

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