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New techniques to improve classical corneal collagen cross-linking treatment

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Chinese Medical Journal 2014年第8期127卷 1558-1565页

作者： li Na peng Xiujun fan Zhengjun Xia Yu Wu Tengfei Department of Ophthalmology Navy General Hospital of Chinese People's Liberation Army Beijing 100048 China

Objective The aim of this review is to comprehensively and unbiasedly summarize the improvements in the techniques for classical corneal collagen cross-linking （CXL） by covering the reasons for this improvement, measure, and effect to approach the future direction of the CXL. Data sources All articles used in this review were mainly retrieved from the PubMed database. Study selection Original articles and reviews were selected if they were related to the improvement in the technique of classical CXL. Data were mainly extracted from 94 articles, which are listed in the reference section of this review. Results This innovative research involves every step such as instrument preparation, epithelial management, riboflavin instillation, and UVA irradiation. These clinical and experimental results seem promising. Conclusions CXL treatment is the only recent promising method for preventing the progress of keratoconus. The limitations and potential complications that accompany classical CXL such as corneal thickness limitations, ultraviolet-A （UVA） light injury, and the impact of de-epithelialization encourage people to research new improvements in techniques. While this research needs to be further investigated, we hope our review can help related researchers and patients.

关键词： cornea cross-linking keratoconus riboflavin UVA radiation

Establishment and study of a polarized X-ray radiation facility

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Nuclear Science and Techniques 2023年第8期34卷 54-63页

作者： Xing Zhou Xiao-Yu Qie Si-Ming Guo Yong-Bo Huang Zi-Yao Shu Shi-Kui Huang li-peng fan Kai-Yue Guo Tao Yu Jin-Jie Wu School of Physical Science and Technology Guangxi UniversityNanning 530004China National Institute of Metrology Beijing 100029China

With the advancement in X-ray astronomical detection technology,various celestial polarization detection projects have been *** meet the calibration requirements of polarimeters on the ground,a polarized X-ray radiation facility was designed for this *** design was based on the principle that X-rays incident at 45°on a crystal produce polarized X-rays,and a second crystal was used to measure the polarization of the X-rays produced by the facility after *** effects of different diaphragm sizes on the degree of polarization were compared,and the facility produced X-rays with polarization degrees of up to 99.55±0.96%using liF200 and liF220 *** result revealed that the polarization of incident X-rays is one of the factors affecting the diffraction efficiency of *** replacement of different crystals can satisfy the calibration requirements of polarized X-ray detectors with more energy points in the energy range(4-10)*** the future,the facility should be placed in a vacuum environment to meet the calibration requirements at lower energies.

关键词： Polarized X-rays Polarimetry Calibration Bragg diffraction

Preliminary study on a single balloon cross-midline expansion via unipedicular approach in kyphoplasty

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Chinese Medical Journal 2008年第18期121卷 1811-1814页

作者： SUN Gang JIN peng li fan-dong liU Xun-wei HAO Run-song YI Yu-hai XIE Zhi-yong Department of Medical Imaging Jinan Military General Hospital of People's Liberation Army Jinan Shandong 250031 China

Background Recently, bilateral transpedicular kyphoplasty with a single balloon was performed for osteoporotic vertebral body compression fractures （OVCFs） to reduce the fees of the operation, but the time of operation and radiation exposure are longer. The aim of this study was to determine the safety and effectiveness of a single balloon cross-midline expansion via unipedicular approach in kyphoplasty for OVCFs. Methods Thirty-six patients with painful OVCFs （61 vertebrae） were enrolled in this research. Unilateral transpedicular puncture was performed under the fluoroscopy monitoring of an oblique angle down the pedicle. A single balloon was introduced through unipedicular approach, The final balloon position was in the midline of the vertebral body with the balloon cross-midline expansion and bone cement filled. Clinical outcomes were determined by comparison of the preoperative and postoperative visual analogue scale （VAS） and Oswestry disability index （ODI）. Radiographic assessment included restoration of vertebral height and correction of kyphosis. Follow-up was conducted for 6-12 months （mean 9.2 months）. Results Thirty-six consecutive patients with 61 vertebrae were successfully operated on with a mean operation time of 37.4 minutes per vertebra. All patients had dramatic pain relief and functional recovery within 96 hours after the procedure with no surgery or device-related complications. VAS score improved from 7.27±1.02 preoperatively to 2.71±0.75 postoperatively （P 〈0.01）. ODI score was decreased from （71.14±10.94）% preoperatively to （26.56±6.35）% postoperatively. The average loss of anterior body height was （14.33±2.76） mm before procedure and （10.03±1.83） mm after procedure （P 〈0.01）, while the average loss of middle body height was （10.15±2.70） mm before procedure and （5.89±1.83） mm after procedure （P 〈0.01）. The kyphotic deformity was corrected from （23.43±5.00） degree to （16.16±2.77） degree （P 〈0.01）. The pain relief and functional recovery were s

关键词： radiology, interventional kyphoplasty osteoporosis spinal fractures

Responses of Soybean GmSARK Gene to Environmental Stresses

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Responses of Soybean GmSARK Gene to Environmental Stresses

Correlation between the rock mass properties and maximum horizontal stress:A case study of overcoring stress measurements

2007中国植物生理学会全国学术会议

作者： peng-li li fan Xu Dong liu Ning Ning Wang (Department of Plant Biology and Ecology,Nankai University,Tianjin 300071,China)

＜正＞Leaf senescence is a form of programmed cell *** in gene expression and signalling pathways between developmental and stress-induced senescence in higher plants have been largely reported. We have previously described a soybean LRR-RLK gene,GmSARK,which plays an important role in regulation of soybean leaf *** also found that over-expression of GmSARK gene greatly

关键词： Soybean GrnSARK RLK Senescence Environmental Stress

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 39-48页

作者： peng li Meifeng Cai Shengjun Miao Yuan li Yu Wang Key Laboratory of Ministry of Education for Efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Coal Resources and Safe Mining China University of Mining and TechnologyXuzhou 221116China

Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress *** investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution *** results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with *** is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and ***,there is no obvious relationship between the rock quality designation(RQD)and *** maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same *** addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.

关键词： overcoring stress measurements elastic modulus Poisson's ratio rock quality designation maximum horizontal stress fuzzy identification

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di fan Wan Wang Bin Wang Ju-Yun Ma peng-peng li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

Bowel preparation before colonoscopy: Consequences, mechanisms, and treatment of intestinal dysbiosis

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World Journal of Gastroenterology 2025年第2期31卷 13-26页

作者： Ze-Long Zheng Qing-fan Zheng li-Qiang Wang Yi liu Department of Gastroenterology(Endoscopy Center) China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

The term“gut microbiota”primarily refers to the ecological community of various microorganisms in the gut,which constitutes the largest microbial community in the human *** adequate bowel preparation can improve the results of colonoscopy,it may interfere with the gut *** preparation for colonoscopy can lead to transient changes in the gut microbiota,potentially affecting an individual’s health,especially in vulnerable populations,such as patients with inflammatory bowel ***,measures such as oral pro-biotics may ameliorate these adverse *** focused on the bowel prepa-ration-induced changes in the gut microbiota and host health status,hypothesized the factors influencing these changes,and attempted to identify measures that may reduce dysbiosis,thereby providing more information for individualized bowel preparation for colonoscopy in the future.

关键词： Bowel preparation Colonoscopy Microbiota Inflammatory bowel disease Probiotics

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao Xiang Feng Gao Yu-Gui peng peng Wu Zong-lin li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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光照对辅助生殖实验室胚胎发育的负面影响

实用医院临床杂志 2014年第6期11卷 201-203页

作者：彭礼繁四川省医学科学院.四川省人民医院辅助生殖医学中心四川成都610072

IVF实验室的胚胎发育会受到紫外线、可见光和太阳光等外界光源,光照波长、强度和时间及其光照诱发的不利胚胎培养环境因子的影响,使其胚胎体外发育受损;从光照对胚胎造成损伤的机理分析中,结合实际总结出IVF实验室控制胚胎光照损伤的具... 详细信息

IVF实验室的胚胎发育会受到紫外线、可见光和太阳光等外界光源,光照波长、强度和时间及其光照诱发的不利胚胎培养环境因子的影响,使其胚胎体外发育受损;从光照对胚胎造成损伤的机理分析中,结合实际总结出IVF实验室控制胚胎光照损伤的具体措施。

关键词：光照胚胎发育负面影响