检索结果-南通市图书馆

Beijing, Hebei and Gansu Women's Federations Greet FWCW

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Women of China 1995年第1期 9-10页

作者： XIAO ming li li

IN Semptember 1995 the Fourth World Conference on Women will be held in Beijing. Chinese women regard it as the biggest event to occur in their country. Preparations have already begun to welcome 20,000 sisters from the five continents of the world. Beijing After the Chinese government formed the China Organizing Committee for the Fourth World Conference on Women, the All-China Women’s Federation organized the NGO Forum Committee. In July 1994 the ACWF

关键词： NGO Beijing Hebei and Gansu Women’s Federations Greet FWCW World

Xiadiya:Daughter of the Pamirs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Women of China 1994年第12期 14-16页

作者： XIAO ming li li

ON the Pamir Plateau, 3,200 meters above sea level, live the Tajik people. Almost every Tajik knows the name Xiadiya. She is regarded as the pride of Tajik women, for she is the first female Tajik college student, the first female leader of Taxkorgan Tajik Autonomous County Party Committee and the first female Tajik deputy to come to Beijing to attend

关键词： Xiadiya:Daughter of the Pamirs

EVALUATION OF NEUROPROTECTIVE EFFECTS OF LONG-TERM LOW DOSE HORMONE REPLACEMENT THERAPY ON POSTMENOPAUSAL WO-MEN BRAIN HIPPOCAMPUS USING MAGNETIC RESONANCE SCANNER

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Sciences Journal 2006年第4期21卷 214-218页

作者： ling Hu Yun Yue Ping-ping Zuo Zheng-yu Jin Feng Feng Hui You ming-li li Qin-sheng Ge Department of Radiology 3 Department of Gynecology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Deparment of Pharmacology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100005 不详

To investigate the effects of long-term low dose hormone replacement therapy （HRT） on postmenopaosal women in homone level, cognition score, hippocampus volume, and magnetic resonance spectroscopy （MRS） parameters. Methods A total of 182 postmenopausal women aged 50-87 years were chosen at Peking Union Medical College Hospital and assigned to HRT group and control group. The volunteers of HRT group had taken low dose hormone [ estradiol （E2 ） 0. 5-1.0 mg and progesterone 0.5-2.0 mg, once a day ] for 4-33 years. The concentrations of E2, progesterone, and testosterone were measured using enzyme-linked immunosorbent assay （EliSA）. The gene types of apolipoprotein E （ApoE） were measured by polymerase chain reaction, and the subjects with susceptible genes （ ApoE ε3/ε4） of Alzheimer＇s disease （AD） were screened. Their hippocampus volumes and MRS parameters were obtained through magnetic resonance imaging （MRI）, and results in two groups were analyzed by statistical method. Results Compared with control group, the concentrations of E2 at each age stage in HRT group were significantly higher （P 〈0. 05） except the 80-89 years old subgroup; yet, there were no statistical differences in the concentrations of progesterone and testosterone between the two groups. There was no obvious difference in ApoE subtypes distribution between the two groups The results of hippocampus MRI for the subjects with susceptible genes ApoE ε3/ε4 （HRT group 14 cases, control group 11 cases） showed that the ratio of bilateral hippocampus volume to whole brain volume in HRT group （0. 406 ± 0.028） was signiticantlyhigher than control gronp （0.369±0.031, P〈0.05）. Theresults of ^1H MRS for the subjects with susceptible genes ApoE ε3/ε4 （ HRT group 12 cases, control group 11 cases） showed that the N-acetylaspartate/total creatine at the area of hippocampus in HRT group （ 1.54±0. 08 ） were significantly higher than control group （ 1.45±0. 13, P 〈 0. 05）. Conclusions For postmenopausal women, long-ter

关键词： long-term low dose hormone replacement therapy estrogen apolipoprotein E hippocampus magnetic resonance spectroscopy

Risk factors for mortality after coronary artery bypass grafting in patients with low left ventricular ejection fraction

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2007年第4期120卷 317-322页

作者： WANG Jin XIAO Feng REN Jian li Yan ZHANG ming-li Department of Cardiac Surgery Peking University First Hospital Beijing 100034 China

Background We managed to assess and confirm the risk factors for mortality after coronary artery bypass grafting （CABG） operations so as to map out the proper guidance of surgical strategy especially in patients with low left ventncular ejection fraction （LVEF） in domestic polyclinic like ours. Methods Five hundred and forty-eight consecutive patients underwent CABG from December 1999 through August 2005 were analyzed retrospectively. Eighty-nine cases had an LVEF of 40% or less. All together twenty-two candidate factors were evaluated for their association with perioperative death using univariate and multivariate stepwise Logistic analysis. Results When data from all the patients who had undergone CABG were taken into account, LVEF, left ventricular end diastolic diameter （LVEDD）, mitral regurgitation, aneurysm of the heart wall, mitral repair/replacement, resection of aneurysm, concomitant aortic valve replacement, and perioperative intra-aortic balloon counter-pulsation （IABP）, left ventricular assist device （LVAD） and cardiopulmonary bypass （CPB） all showed an association with perioperative death in univariate analysis, while an LVEF of 〉40%, on the other hand, appeared to be a protective factor. In multivariate analysis, moderate to severe mitral regurgitation, aneurysm of the heart wall, repair of septal perforation and aortic regurgitation were proved to be risk factors. When the analysis was restricted to patients with an LVEF of 40% or less, such variables as age, LVEDD, mitral regurgitation, mitral repair/replacement, IABP, and CPB were qualified as risk factors in a univariate analysis. Age, moderate mitral regurgitation, aneurysm of the heart wall, CPB, left main coronary artery disease and female were associated with pefioperative death in a multivariate logistic regression analysis. Conclusions Concerning the prognosis, patients who undergo CABG would have different risk factors when data from all the enrolled patients or data from patients with

关键词： ventricular dysfunction, left coronary artery bypass risk factors

Gene expression in rat mesenchymal stem cells following treatment with natural cerebrolysin-containing serum Validation of a whole genome microarray technique

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2010年第6期5卷 424-432页

作者： Yinghong li Zhengzhi Wu ming li Xiuqin Jia Min Yang Manyin Chen First Affiliated Hospital of Shenzhen University Shenzhen Institute of Integrated Chinese and Western Medicine Shenzhen 518035Guangdong Province China

BACKGROUND： Natural cerebrolysin （NC）, a Chinese herbal drug for the treatment of Alzheimer＇s disease （AD）, induces mesenchymal stem cell （MSC） differentiation into neuron-like cells, with low toxicity. But the mechanisms involved in NC effects on MSCs remain poorly understood. OBJECTIVE： We used a whole genome microarray technique to further investigate the molecular, genetic, and pharmacodynamic mechanisms of NC on MSC gene expression profiles. DESIGN, TIME AND SETTING： A parallel, controlled, in vitro experiment was performed at the First Affiliated Hospital of Shenzhen University, Shenzhen Institute of Integrated Chinese and Western Medicine, China, between September 2006 and October 2008. MATERIALS： NC was provided by Shenzhen Institute of Integrated Chinese and Western Medicine China. It was predominantly composed of Renshen （Radix Ginseng）, Tianma （Rhizoma Gastrodiae） and Yinxingye （Ginkgo Leaf） and prepared by conventional water extractJon technology. Twelve adult, male, New Zealand rabbits were included, six of which underwent intragastric administration of NC extract for 1 month to create NC-containing serum. METHODS： Bone marrow was collected from the tibia and femur of Sprague Dawley rats, aged 6 8 months old. Rat MSCs were isolated and purified by the whole bone marrow adherence method. After in vitro culture, MSCs from passage 4 were treated with NC-containing serum for 48 hours, and total RNA was extracted. Gene expression in MSCs was analyzed using Affymetrix whole genome microarray analysis. MAIN OUTCOME MEASURES： Differentially expressed genes in NC serum-treated MSCs. RESULTS： NC treated MSCs displayed 46 differentially expressed genes, 22 with upregulated expression （fold change 〉 2） and 24 with downregulated expression （fold change 〈 -2）. Differentially expressed genes participated in neuronal growth, differentiation, and function, cell growth, differentiation, proliferation, apoptosis, signal transduction, substance/energy metabolism, ion trans

关键词： natural cerebrolysin whole genome chip mesenchymal stem cells gene expression profile Alzheimer's disease neural regeneration neurodegenerative disease

Analysis on hidden blood loss of total knee arthroplasty in treating knee osteoarthritis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2011年第11期124卷 1653-1656页

作者： SHEN Hui-liang li Zheng FENG ming-li CAO Guang-le Department of Orthopaedics Xuanwu Hospital Capital MedicalUniversity Beijing 100053 China

Background Total knee arthroplasty （TKA） is an important therapy for the treatment of various late-stage knee diseases. However, it has been observed that patients have lower hemoglobin （HB） counts postoperatively, which are significantly inconsistent with the measured blood loss. Although the concept of hidden blood loss has been presented in 2000, very little clinical attention has been paid since then. In this study, we investigated the characteristics and influential factor of hidden blood loss after TKA in treating knee osteoarthritis.

关键词： total knee arthroplasty hidden blood loss reinfusion osteoarthritis

Sequential Extraction of Natural Surface Coatings: Comparison with Single Stage Extraction and Its Application in Investigating Adsorption Characteristics of Surface Coating Components for Metals

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2012年第1期28卷 41-46页

作者： HUA Xiu-yi, liU Xiao-xue, DONG De-ming, li ming and li Yao-rui Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Key Lab of Water Resources and Aquatic Environment of Jilin Province, College of Environment and Resources, Jilin University, Changchun 130012, P. R. China Jilin Univ Key Lab Groundwater Resources & Environm Key Lab Water Resources & Aquat Environm Jilin Pr Minist EducColl Environm & Resources Changchun 130012 Peoples R China

Multistage sequential extraction with different sequences was applied to extracting natural surface coa tings（NSCs）, and the results were compared with those by single stage extraction technique. The optimal sequential extraction scheme with the best performance was selected and incorporated into the method of selective extraction followed by adsorption and statistic analyses to study the adsorption parameters of Fe oxides, Mn oxides and organic matters in NSCs for Pb and Cd, to validate the applicability of the sequential extraction scheme. The Langmuir ad sorption parameters of each component of surface coating estimated according to the adsorption data of single stage extraction of NSCs were all similar to those of sequential extraction of NSCs, and the maximum difference between the metal adsorption abilities of the components estimated via the two extraction techniques was only about 20%, in dicating that either extraction techniques could be used. The optimal sequential extraction scheme obtained was first extracted with NH2OH·HCl, then with Na2S2O4, and finally with oxalic acid.

关键词： Natural surface coating(NSC) Sequential extraction Single stage extraction Adsorption Component

Application of computed tomography-based radiomics in differential diagnosis of adenocarcinoma and squamous cell carcinoma at the esophagogastric junction

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第31期28卷 4363-4375页

作者： Ke-Pu Du Wen-Peng Huang Si-Yun liu Yun-Jin Chen li-ming li Xiao-Nan liu Yi-Jing Han Yue Zhou Chen-Chen liu Jian-Bo Gao Department of Radiology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Department of Pharmaceutical Diagnostics General Electric Company HealthcareBeijing 100176China Department of Pathology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina

BACKGROUND The biological behavior of carcinoma of the esophagogastric junction(CEGJ)is different from that of gastric or esophageal *** squamous cell carcinoma of the esophagogastric junction(SCCEG)from adenocarcinoma of the esophagogastric junction(AEG)can indicate Siewert stage and whether the surgical route for patients with CEGJ is transthoracic or transabdominal,as well as aid in determining the extent of lymph node *** the development of neoadjuvant therapy,preoperative determination of pathological type can help in the selection of neoadjuvant radiotherapy and chemotherapy *** To establish and evaluate computed tomography(CT)-based multiscale and multiphase radiomics models to distinguish SCCEG and AEG *** We retrospectively analyzed the preoperative contrasted-enhanced CT imaging data of single-center patients with pathologically confirmed SCCEG(n=130)and AEG(n=130).The data were divided into either a training(n=182)or a test group(n=78)at a ratio of 7:3.A total of 1409 radiomics features were separately extracted from two dimensional(2D)or three dimensional(3D)regions of interest in arterial and venous ***-/inter-observer consistency analysis,correlation analysis,univariate analysis,least absolute shrinkage and selection operator regression,and backward stepwise logical regression were applied for feature ***,six logistic regression models were established based on 2D and 3D multi-phase *** receiver operating characteristic curve analysis,the continuous net reclassification improvement(NRI),and the integrated discrimination improvement(IDI)were used for assessing model discrimination *** and decision curves were used to assess the calibration and clinical usefulness of the model,*** The 2D-venous model(5 features,AUC:0.849)performed better than 2D-arterial(5 features,AUC:0.808).The 2D-arterial-venous combined model could further e

关键词： Esophagogastric junction Squamous cell carcinoma Adenocarcinoma X-ray computed tomography Radiomics

Stroke-like Migraine Attacks after Radiation Therapy Syndrome

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第15期128卷 2097-2101页

作者： Qian Zheng li Yang li-ming Tan li-Xia Qin Chun-Yu Wang Hai-Nan Zhang Department of Neurology Second Xiangya Hospital Central South University Changsha Hunan 410011 China

Objective：To summarize the clinical presentation,pathogenesis,neuroimaging,treatment,and outcome of stroke-like migraine attacks after radiation therapy （SMART） syndrome,and to propose diagnostic criteria for this *** Sources：We searched the PubMed database for articles in English published from 1995 to 2015 using the terms of ＂stroke-like AND migraine AND radiation.＂ Reference lists of the identified articles and reviews were used to retrieve additional *** Selection：Data and articles related to late-onset effects of cerebral radiation were selected and ***：SMART is a rare condition that involves complex migraines with focal neurologic deficits following cranial irradiation for central nervous system *** recovery,which ranges from hours to days to weeks,can be partial or *** propose the following diagnostic criteria for SMART：（1） Remote history of therapeutic external beam cranial irradiation for malignancy;（2） prolonged,reversible clinical manifestations mostly years after irradiation,which may include migraine,seizures,hemiparesis,hemisensory deficits,visuospatial defect,aphasia,confusion and so on;（3） reversible,transient,unilateral cortical gadolinium enhancement correlative abnormal T2 and fluid-attenuated inversion recovery signal of the affected cerebral region;（4） eventual complete or partial recovery,the length of duration of recovery ranging from hours to days to weeks;（5） no evidence of residual or recurrent tumor;（6） not attributable to another *** date,no specific treatment has been identified for this ***：SMART is an extremely rare delayed complication of brain ***,improvements in cancer survival rates have resulted in a rise in its ***,awareness and recognition of the syndrome is important to make a rapid diagnosis and avoid aggressive interventions such as brain biopsy and cerebral angiography.

关键词： Cranial Irradiation Epilepsy Migraine Stroke-like Migraine Attacks after Radiation Therapy