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Paired quasi-periodic pulsations of hard X-ray emission in a solar flare

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Science China(Physics,Mechanics & Astronomy) 2023年第5期66卷 195-206页

作者： hai-Sheng Zhao Dong li Shao-lin Xiong Yan-Qiu zhang Yang Su Wei chen Yi Zhao Xiao-Bo li Jia-Cong liu Wen-Xi Peng Rui Qiao Xin-Qiao li Xiang-Yang Wen li-Ming Song Shi-Jie Zheng Xin-Ying Song Xiao-yun Zhao yue Huang Shuang-Nan zhang Shuo Xiao Ce Cai Zheng-Hua An Can chen Gang chen Wei chen Yan-Qi Du Min Gao Ke gong Dong-Ya Guo Zhi-Wei Guo Jian-Jian he Bin li Chao li Chao-Yang li Gang li Jian-Hui li Lu li Qing-Xin li Yan-Guo li Jing liang Xiao-Hua liang Jin-yuan liao Xiao-Jing liu Ya-Qing liu Qi Luo Xiang Ma Bin Meng Ge Ou Dong-li Shi Jing-Yan Shi gong-Xing Sun Xi-Lei Sun You-li Tuo chen-Wei Wang Hui Wang Jin Wang Jin-zhou Wang Ping Wang Wen-Shuai Wang Hong Wu Sheng-Lun Xie Yan-Bing Xu yu-Peng Xu Wang-chen Xue Sheng Yang Min Yao Jian-Ying Ye Qi-Bin Yi Chao-yue zhang Da-li zhang Fan zhang Fei zhang Hong-Mei zhang Kai zhang Peng zhang Xiao-Lu zhang Zhen zhang Guo-Ying Zhao Shi-Yi Zhao Chao Zheng Xing zhou yue zhu Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China University of Chinese Academy of Sciences Beijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China Physics and Space Science College China West Normal UniversityNanchong 637002China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Institute of Astrophysics Central China Normal UniversityWuhan 430079China School of Physics Changchun University of Science and TechnologyChangchun 130022China College of Physics and Engineering Qufu Normal UniversityQufu 273165China College of Physics Sciences&Technology Hebei UniversityBaoding 071002China

We investigate high time resolution data obtained by the Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)during the flare event on 2022 April 21 at 01:52 *** subpeaks with durations of 4-6 s have been detected in the hard X-ray precursor phase,and the key feature is that they appear in pairs and seem like double-peak *** subpeaks are rarely observed in hard X-ray band and confirmed by the microwave obtained by Nobeyama Radio Polarimeters(NoRP)and Radio Solar Telescope Network(RSTN).While an exponential function can describe the continuum component of the time profile from the precursor to part of the impulsive *** periods of quasi-periodic pulsations(QPPs)are detected to be about 7.3 and 12.8 s for the precursor and impulsive phase,respectively,with at least 95%confidence *** paired QPPs are assumed to be double-peak QPPs and then the scenario of current loop coalescence model is found to be in good agreement with our *** precursor phase can be interpreted as the oscillating coalescence of two islands,while the impulsive phase can be interpreted as more islands to coalesce one by one to form larger islands.

关键词： solar flare QPPs loop coalescence circular-ribbon flare

First results on ^(76)Ge neutrinoless double beta decay from CDEX-1 experiment

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Science China(Physics,Mechanics & Astronomy) 2017年第7期60卷 53-59页

作者： li Wang Qian yue KeJun Kang JianPing cheng yuanJing li TszKing henry Wong ShinTed lin JianPing Chang JingHan chen QingHao chen yunHua chen Zhi Deng Qiang Du Hui gong li he QingJu he JinWei Hu HanXiong Huang TengRui Huang liPing Jia Hao Jiang HauBin li Hong li JianMin li Jin li Jun li Xia li XueQian li yuLan li FongKay lin ShuKui liu Hao Ma JingLu Ma Xingyu Pan Jie Ren XiChao Ruan ManBin Shen Vivek Sharma Lakhwinder Singh Manoj Kumar Singh Manoj Kumar Singh Arun Kumar Soma ChangJian Tang WeiYou Tang ChaoHsiung Tseng JiMin Wang Qing Wang ShiYong Wu yucheng Wu HaoYang Xing Yin Xu Tao Xue liTao Yang SongWei Yang Nan Yi ChunXu yu haiJun yu Weihe Zeng XiongHui Zeng Zhi Zeng Lan zhang yunHua zhang MingGang Zhao Wei Zhao JiFang zhou ZuYing zhou JingJun zhu WeiBin zhu ZhongHua zhu Key Laboratory of Particle and Radiation Imaging (Ministry of Education) and Department of Engineering Physics Tsinghua University Institute of Physics Academia Sinica School of Physical Science and Technology Sichuan University NUCTECH Company YaLong River Hydropower Development Company Department of Nuclear Physics China Institute of Atomic Energy School of Physics Nankai University Department of Physics Banaras Hindu University

We report the first results on 76Ge neutrinoless double beta decay from stage one of the China dark-matter experiment （CDEX）. A p-type point-contact high-purity germanium detector with a mass of 994g has been installed to detect neutrinoless double beta decay events, as well as to directly detect dark matter particles. An exposure of 304kgd has been analyzed over a wide spectral band from 500keV to 3MeV. The average event rate obtained was about 0.012 counts per keV per kg per day over the 2.039MeV energy range. The half-life of76Ge neutrinoless double beta decay derived based on this result is 70v2〉6.4× 1022 yr （90%C.L.）. An upper limit on the effective Majorana-neutrino mass of 5.0eV has been achieved.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector 76Ge isotope

The 2022 report of synergetic roadmap on carbon neutrality and clean air for China:Accelerating transition in key sectors

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Environmental Science and Ecotechnology 2024年第3期19卷 4-18页

作者： yu Lei Zhicong Yin Xi Lu Qiang zhang Jicheng gong Bofeng Cai Cilan Cai Qimin Chai Huopo chen Renjie chen Shi chen Wenhui chen Jing cheng Xiyuan Chi Hancheng Dai Xiangzhao Feng Guannan Geng Jianlin Hu Shan Hu Cunrui Huang Tiantian li Wei li Xiaomei li Jun liu Xin liu zhu liu Jinghui Ma yue Qin Dan Tong Xuhui Wang Xuying Wang Rui Wu Qingyang Xiao Yang Xie Xiaolong Xu Tao Xue haipeng yu Da zhang Ning zhang Shaohui zhang Shaojun zhang Xian zhang Xin zhang Zengkai zhang Bo Zheng Yixuan Zheng Jian zhou Tong zhu Jinnan Wang Kebin he Center of Air Quality Simulation and System Analysis Chinese Academy of Environmental PlanningBeijing100041China Center for Carbon Neutrality Chinese Academy of Environmental PlanningBeijing100041China Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment Change(ILCEC)/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science&TechnologyNanjing210044China State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing100084China Institute for Carbon Neutrality Tsinghua UniversityBeijing100084China Ministry of Education Key Laboratory for Earth System Modelling Department of Earth System ScienceTsinghua UniversityBeijing100084China State Key Joint Laboratory for Environment Simulation and Pollution Control College of Environmental Sciences and Engineering and Center for Environment and HealthPeking UniversityBeijing100871China National Center for Climate Change Strategy and International CooperationBeijing100035China Nansen-zhu International Research Centre Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing100029China School of Public health Key Lab of Public Health Safety of the Ministry of Education and Key Lab of Health Technology Assessment of the Ministry of HealthFudan UniversityShanghai200032China School of Economics and Management Beijing University of Chemical TechnologyBeijing100029China Department of Earth System Science University of CaliforniaIrvineCA92697USA National Meteorological Center China Meteorological AdministrationBeijing100081China College of Environmental Sciences and Engineering Peking UniversityBeijing100871China Policy Research Center for Environment and Economy Ministry of Ecology and Environment of the People's Republic of ChinaBeijing100029China Jiangsu Key Laboratory of Atmospheric Environment Monitoring

China is now confronting the intertwined challenges of air pollution and climate *** the high synergies between air pollution abatement and climate change mitigation,the Chinese government is actively promoting synergetic control of these two *** Synergetic Roadmap project was launched in 2021 to track and analyze the progress of synergetic control in China by developing and monitoring key *** Synergetic Roadmap 2022 report is the first annual update,featuring 20 indicators across five aspects:synergetic governance system and practices,progress in structural transition,air pollution and associated weather-climate interactions,sources,sinks,and mitigation pathway of atmospheric composition,and health impacts and benefits of coordinated *** to the comprehensive review presented in the 2021 report,the Synergetic Roadmap 2022 report places particular emphasis on progress in 2021 with highlights on actions in key sectors and the relevant *** milestones include the proportion of non-fossil power generation capacity surpassing coal-fired capacity for the first time,a decline in the production of crude steel and cement after years of growth,and the surging penetration of electric ***,in 2022,China issued the first national policy that synergizes abatements of pollution and carbon emissions,marking a new era for China's pollution-carbon *** changes highlight China's efforts to reshape its energy,economic,and transportation structures to meet the demand for synergetic control and sustainable ***,the country has witnessed a slowdown in carbon emission growth,improved air quality,and increased health benefits in recent years.

关键词： Synergetic roadmap Carbon neutrality Clean air

Performances of a prototype point-contact germanium detector immersed in liquid nitrogen for light dark matter search

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Science China(Physics,Mechanics & Astronomy) 2019年第3期62卷 58-65页

作者： Hao Jiang liTao Yang Qian yue KeJun Kang JianPing cheng yuanJing li henry Tsz-King Wong M.A?artio?lu haiPeng An JianPing Chang JingHan chen yunHua chen Zhi Deng Qiang Du Hui gong li he Jin Wei Hu QingDong Hu HanXiong Huang liPing Jia HauBin li Hong li Jian Min li Jin li Xia li XueQian li yuLan li Bin liao FongKay lin ShinTed lin ShuKui liu YanDong liu yuanyuan liu ZhongZhi liu Hao Ma JingLu Ma Hui Pan Jie Ren XiChao Ruan B.Sevda Vivek Sharma ManBin Shen Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang JiMin Wang li Wang Qing Wang Yi Wang ShiYong Wu yucheng Wu HaoYang Xing Yin Xu Tao Xue SongWei Yang Nan Yi ChunXu yu haiJun yu JianFeng yue XiongHui Zeng Ming Zeng Zhi Zeng FengShou zhang yunHua zhang MingGang Zhao JiFang zhou ZuYing zhou JingJun zhu ZhongHua zhu Key Laboratory of Particle and Radiation Imaging (Ministry of Education)and Department of Engineering Physics Tsinghua University College of Nuclear Science and Technology Beijing Normal University Institute of Physics Academia Sinica Department of Physics Dokuz Eylül University Department of Physics Tsinghua University NUCTECH Company Ya Long River Hydropower Development Company College of Physical Science and Technology Sichuan University Department of Nuclear Physics China Institute of Atomic Energy School of Physics Nankai University Department of Physics Banaras Hindu University Department of Physics Beijing Normal University

The CDEX-10 experiment searches for light weakly interacting massive particles, a form of dark matter, at the China Jinping Underground Laboratory, where approximately 10 kg of germanium detectors are arranged in an array and immersed in liquid nitrogen. herein, we report on the experimental apparatus, detector characterization, and spectrum analysis of one prototype detector. Owing to the higher rise-time resolution of the CDEX-10 prototype detector as compared with CDEX-1 B, we identified the origin of an observed category of extremely fast events. For data analysis of the CDEX-10 prototype detector, we introduced and applied an improved bulk/surface event discrimination method. The results of the new method were compared to those of the CDEX-1 B spectrum. Both sets of results showed good consistency in the 0-12 ke Vee energy range, except for the 8.0 keV K-shell X-ray peak from the external copper.

关键词： WIMP pPCGe liquid nitrogen bulk/surface event discrimination extremely fast events

Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

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Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： Sheng-Da Tang Yong-Hao chen Jing-yu Tang Rui-Rui Fan Qiang li gong li Dong liu Zheng-Yao Jin Xing-zhu Cui Tian-Xiang chen Yi-Wei Yang Rong liu Han Yi Yang li Zhen Yang Qi An Hao-Fan Bai Jiang-Bo Bai Jie Bao Ping Cao Qi-Ping chen Zhen chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-zhu he Yong-cheng he Yang Hong Yi-Wei Hu Han-Xiong Huang Wei-Hua Jia Hao-yu Jiang Wei Jiang Zhi-jie Jiang ling Kang Bo li Chao li Jia-Wen li Xiao li Jie liu Shu-Bin liu Guang-yuan Luan Chang-Jun Ning Bin-Bin Qi Jie Ren Zhi-zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Xin Tan li-Jiao Wang Peng-cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu li-Kun Xie Yong-Ji yu Guo-Hui zhang lin-Hao zhang Mo-Han zhang Qi-Wei zhang Xian-Peng zhang yu-liang zhang yue zhang Zhi-Yong zhang Mao-yuan Zhao Lu-Ping zhou Zhi-Hao zhou Ke-Jun zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron *** resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an *** back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test *** results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at *** study reveals its potential future applications.

关键词： CSNS White neutron beam NRTA Nuclide identification Nondestructive method

Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

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Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang li li‑Jiao Wang Xiang‑Biao Qiu Jing‑Wen li Wei Xu Tao li Ze‑Bin lin Chang‑Jun Ning Yong‑Hao chen Rui‑Rui Fan Kang Sun Jing‑yu Tang Rong zhang Han‑Tao Jing Bo Mei Qi An Hao‑Fan Bai Jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping chen Zhen chen Zeng‑Qi Cui An‑Chuan Fan Chang‑Qing Feng Fan‑Zhen Feng Ke‑Qing Gao Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑zhu he Yong‑cheng he Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei‑Hua Jia Hao‑yu Jiang Wei Jiang Zhi‑Jie Jiang Zheng‑Yao Jin ling Kang Bo li Chao li gong li Jia‑Wen li Xiao li Yang li Jie liu Rong liu Shu‑Bin liu Guang‑yuan Luan Bin‑Bin Qi Jie Ren Zhi‑zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Zhi‑Xin Tan Sheng‑Da Tang Peng‑cheng Wang Zhao‑Hui Wang Zhong‑Wei Wen Xiao‑Guang Wu Xuan Wu li‑Kun Xie Yi‑Wei Yang Han Yi Yong‑Ji yu Guo‑Hui zhang lin‑Hao zhang Mo‑Han zhang Qi‑Wei zhang Xian‑Peng zhang yu‑liang zhang yue zhang Zhi‑Yong zhang Mao‑yuan Zhao Lu‑Ping zhou Zhi‑Hao zhou Ke‑Jun zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons

First experimental constraints on WIMP couplings in the effective field theory framework from CDEX

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Science China(Physics,Mechanics & Astronomy) 2021年第8期64卷 15-22页

作者： Yi Wang Zhi Zeng Qian yue liTao Yang KeJun Kang yuanJing li Mehment Agartioglu haiPeng An JianPing Chang JingHan chen yunHua chen JianPing cheng cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui gong QiuJu Guo Xuyuan Guo HongJian he li he ShengMing he JinWei Hu Tuchen Huang HanXiong Huang haiTao Jia liPing Jia Xi Jiang HauBin li JianMin li Jin li MingXuan li RenMingJie li Xia li yuLan li Bin liao FongKay lin ShinTed lin ShuKui liu YanDong liu yu liu yuanyuan liu ZhongZhi liu Hao Ma yuCai Mao Qiyuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang li Wang Qing Wang yu chen Wang yunXiang Wang Zhen Wang henry Tsz-King Wong ShiYong Wu yucheng Wu HaoYang Xing Yin Xu Tao Xue yuLu Yan Nan Yi ChunXu yu haiJun yu JianFeng yue Ming Zeng BingTao zhang Lei zhang FengShou zhang Zhenyu zhang KangKang Zhao MingGang Zhao JiFang zhou ZuYing zhou JingJun zhu Key Laboratory of Particle and Radiation Imaging(Ministry of Education) Department of Engineering PhysicsTsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Institute of Physics Academia SinicaTaipei 11529China NUCTECH Company Beijing 100084China YaLong River Hydropower Development Company Chengdu 610051China College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875China College of Physics Sichuan UniversityChengdu 610065China School of Physics Peking UniversityBeijing 100871China Sino-French Institute of Nuclear and Technology Sun Yet-sen UniversityZhuhai 519082China Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413China Department of Physics Banaras Hindu UniversityVaranasi 221005India Department of Physics Beijing Normal UniversityBeijing 100875China School of Physics Nankai UniversityTianjin 300071China

We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region.

关键词： WIMP EFT CDEX dark matter annual modulation

Genome degradation promotes Salmonella pathoadaptation by remodeling fimbriae-mediated proinflammatory response

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National Science Review 2023年第10期10卷 32-43页

作者： Xiao zhou Xiamei Kang Jiaqi chen Yan Song chenghao Jia lin Teng Yanting Tang Zhijie Jiang Xianqi Peng Xiaoxi Tao Yiwei Xu linlin Huang Xuebin Xu Yaohui Xu Tengfei zhang Shenye yu Jiansen gong Shaohui Wang yuqing liu Guoqiang zhu Corinna Kehrenberg Fran?ois-Xavier Weill Paul Barrow Yan li Guoping Zhao Min yue Institute of Preventive Veterinary Sciences and Department of Veterinary Medicine Zhejiang University College of Animal Sciences Ningbo Academy of Agricultural Sciences hainan Institute of Zhejiang University Department of Microbiology Laboratory Shanghai Municipal Center for Disease Control and Prevention College of Veterinary Medicine Henan University of Animal Husbandry and Economy Key Laboratory of Prevention and Control Agents for Animal Bacteriosis Institute of Animal Husbandry and Veterinary Hubei Academy of Agricultural Sciences Division of Bacterial Diseases State Key Laboratory of Veterinary BiotechnologyHarbin Veterinary Research InstituteChinese Academy of Agricultural Sciences Poultry Institute Chinese Academy of Agricultural Sciences Department of Animal Public health Shanghai Veterinary Research Institute Chinese Academy of Agricultural Sciences Shandong Key Laboratory of Animal Disease Control and Breeding Institute of Animal Science and Veterinary MedicineShandong Academy of Agricultural Sciences College of Veterinary Medicine Yangzhou University Institute for Veterinary Food Science Faculty of Veterinary MedicineJustus-Liebig University Giessen Institut Pasteur Université Paris Cité Unité des bactéries pathogènes entériques School of Veterinary Medicine University of Surrey School of life Science Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences CAS Key Laboratory of Synthetic Biology Institute of Plant Physiology and EcologyShanghai Institutes for Biological SciencesChinese Academy of Sciences Department of Microbiology and Microbial Engineering School of Life SciencesFudan University State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesNational Medical Center for Infectious DiseasesThe First Affiliated Hospital College of Medicine Zhejiang University Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine

Understanding changes in pathogen behavior(*** virulence,a shift in transmission channel) is critical for the public health management of emerging infectious *** degradation via gene depletion or inactivation is recognized as a pathoadaptive feature of the pathogen evolving with the ***,little is known about the exact role of genome degradation in affecting pathogenic behavior,and the underlying molecular detail has yet to be *** large-scale global avian-restricted Salmonella genomes spanning more than a century,we projected the genetic diversity of Salmonella Pullorum(bvSP)by showing increasingly antimicrobial-resistant ST92 prevalent in Chinese *** phylogenomic analysis identified three lineages in bvSP,with an enhancement of virulence in the two recently emerged lineages(L2/L3),as evidenced in chicken and embryo infection ***,the ancestor L1 lineage resembles the Salmonella serovars with higher metabolic flexibilities and more robust environmental tolerance,indicating stepwise evolutionary trajectories towards avian-restricted ***-genome analysis pinpointed fimbrial degradation from a virulent *** later engineeredfim-deletion mutant,and all other five fimbrial systems,revealed behavior switching that restricted horizontal fecal-oral transmission but boosted virulence in *** depleting fimbrial appendages,bvSP established persistent replication with less proinflammation in chick macrophages and adopted vertical transovarial transmission,accompanied by ever-increasing intensification in the poultry ***,we uncovered a previously unseen paradigm for remodeling bacterial surface appendages that supplements virulence-enhanced evolution with increased vertical transmission.

关键词： Salmonella host adaptation pathogenic evolution virulence evolution vertical transmission fimbrial adhesin

Probing dark matter particles from evaporating primordial black holes via electron scattering in the CDEX-10 experiment

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Science China(Physics,Mechanics & Astronomy) 2024年第10期67卷 83-91页

作者： Zhenhua zhang litao Yang Qian yue Kejun Kang yuanjing li haipeng An Greeshma C. Jianping Chang yunhua chen Jianping cheng Wenhan Dai Zhi Deng Changhao Fang Xinping Geng Hui gong Qiuju Guo Tao Guo Xuyuan Guo li he Shengming he Jinwei Hu Hanxiong Huang Tuchen Huang lin Jiang S.Karmakar Haubin li Hanyu li Jianmin li Jin li Qianyun li Renmingjie li Xueqian li yulan li Yifan liang Bin liao FongKay lin ShinTed lin Jiaxuan liu Shukui liu Yandong liu yu liu yuanyuan liu Hao Ma yucai Mao Qiyuan Nie Jinhua Ning Hui Pan Ningchun Qi Jie Ren Xichao Ruan Monoj Kumar Singh Tianxi Sun Changjian Tang Yang Tian Guangfu Wang Junzheng Wang li Wang Qing Wang yufeng Wang yunxiang Wang henry Tsz-King Wong Shiyong Wu yucheng Wu Haoyang Xing Rui Xu Yin Xu Tao Xue yulu Yan Nan Yi Chunxu yu haijun yu Jianfeng yue Ming Zeng Zhi Zeng Bingtao zhang Fengshou zhang Lei zhang Zhenyu zhang Jizhong Zhao Kangkang Zhao Minggang Zhao Jifang zhou Zuying zhou Jingjun zhu CDEX Collaboration Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Institute of Physics Academia SinicaTaipei 11529China NUCTECH Company Beijing 100084China YaLong River Hydropower Development Company Chengdu 610051China College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875China College of Physics Sichuan UniversityChengdu 610065China School of Physics Peking UniversityBeijing 100871China Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413China Sino-French Institute of Nuclear and Technology Sun Yet-sen UniversityZhuhai 519082China School of Physics Nankai UniversityTianjin 300071China Department of Physics Banaras Hindu UniversityVaranasi 221005India Department of Physics Beijing Normal UniversityBeijing 100875China 不详

Dark matter(DM)is a major constituent of the ***,no definite evidence of DM particles(denoted as“χ”)has been found in DM direct detection(DD)experiments to *** is a novel concept of detectingχfrom evaporating primordial black holes(PBHs).We search forχemitted from PBHs by investigating their interaction with target *** examined PBH masses range from 1×10^(15)to 7×10^(16)g under the current limits of PBH abundance *** 205.4 kg·day data obtained from the CDEX-10 experiment conducted in the China Jinping Underground Laboratory,we exclude theχ-electron(χ-e)elastic-scattering cross sectionσ_(χe)~5×10^(-29)cm^(2)forχwith a mass■keV from our *** the higher radiation background but lower energy threshold(160 eV),CDEX-10 fills a part of the gap in the previous ***(m_(χ),σ_(χe))can be determined in the future,DD experiments are expected to impose strong constraints on fPBHfor large MPBHs.

关键词： CDEX primordial black hole light dark matter particle dark matter-electron scattering high purity germanium detector