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检索条件"作者=li yan-mei~* {3. laboratory of bioorganic phosphorus chemistry and chemical biology,department of chemistry,tsinghua university,beijing 100084,p.r.china"
共 161 条 记 录，以下是21-30 订阅
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Synthesis and Character of α-Aminophosphonates Derivatives
Synthesis and Character of α-Aminophosphonates Derivatives
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中国化学会第四届有机化学学术会议
作者： liAO, Xin-Cheng liU, Lun GUO, yan-Chun CAO, Shu-Xia ZHAO, Yu-Fen (Key {3. of chemical biology, department of chemistry, Zhengzhou university, Zhengzhou 450052) (Key {3. for bioorganic phosphorus chemistry and chemical biology of Ministry of Education, department of chemistry, School of life Sciences and Engineering, tsinghua university, beijing 100084)
＜正＞As the analogs of phosphoryl amino acids,α-aminophosphonates and theirs derivatives exhibit a wide range of biological activities. For example many of these compounds are potent antibiotics, enzyme inhibitors a...
来源： cnki会议 评论
Tyrosine phosphorylation regulates nitration sites in peptide:evidence of electron transfer in peptide nitration by peroxynitrite
Tyrosine phosphorylation regulates nitration sites in peptid...
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第七届全国磷化学化工暨第四届海峡化学生物学、生物技术与医药发展讨论会
作者： Wei-Qun Shi yan-mei li Jun-Chen Dong Yu-Fen Zhao Key {3. of bioorganic phosphorous Chernistry&chemical biology(Ministry of Education),department of chemistry,tsinghua university,beijing 100084,p.r.china
proteins are targets of reactive nitrogen species such as peroxynitrite and nitrogen dioxide. Among the various amino acids in proteins, tyrosine and tryptophan residues are especially susceptible to attack by reactiv... 详细信息
来源： cnki会议 评论
Synthesis of Novel piperazine phosphordiamidate derivatives of chrysin
Synthesis of Novel Piperazine phosphordiamidate derivatives ...
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第六届全国化学生物学学术会议
作者： Chen Xiao-Lan~(a*5),li Xi-Yonga,Qu ling-Bob,Jiang Yu-Qina,Chen Sen-Shena,Zhao Yu-Fena,c a Key laboratory of Organic {3. and chemical biology,Henan province,department of chemistry,Zhengzhou university,Zhengzhou,450052,p.r.china b Henan university of Technology,Zhengzhou,450001,p.r.china c Key laboratory for bioorganic {13. {3.,department of chemistry School life Sciences and Engineering,tsinghua university,beijing,10084,p.r.china
＜正＞Chrysin,a widely distributed flavone in plants,was reported to have many biological activities including antibacterial,antioxidant,anti-inflammatory,anti-allergic,anticancer,antiestrogenic,and *** it can inhibit...
来源： cnki会议 评论
Synthesis of some AZT-Coumarin triazoles 5′-hydrogenphosphonates
Synthesis of some AZT-Coumarin triazoles 5′-hydrogenphospho...
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第六届全国化学生物学学术会议
作者： Chen Xiao-Lan~(a*4),li Hui-Naa,Qu Zhi-Boa,Wang Jun-lianga,Lu Jian-Shaa,Zhao Yu-Fena,b a Key laboratory of Organic {3. and chemical biology,Henan province,department of chemistry,Zhengzhou university,Zhengzhou,450052,p.r.china b Key laboratory for bioorganic phosphorus {3.,department of chemistry School life Sciences and Engineering,tsinghua university,beijing,10084
3.-azido-3.-deoxythymidine(AZT) was the first clinically approved drug against HIV infection. AZT itself does not show antiviral activity to terminate the viral DNA clone until it is phosphorylated to the correspond...
来源： cnki会议 评论
Spontaneous polymerization of An Amino Acid Based Amphiphile at Air/water Interface Investigated by ESI-MS and Transmission Ir Spectrometry
Spontaneous Polymerization of An Amino Acid Based Amphiphile...
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第三届全国有机化学学术会议
作者： WANG, Hai-yan XIAO, Yi li, yan-{3. WU, li-Xin YU, Zhi-Wu ZHAO, Yu-Fen bioorganic phosphorus chemistry laboratory, department of chemistry, tsinghua university, beijing 100084 Key laboratory of Supramolecular Structure and Materials , College of chemistry, Jilin university, Changchun 13.023
＜正＞ Self-assemblies of amphiphilic molecules are proposed to play aubiquitous role at the early stages of evolution in the formation of primitive *** regard to the significance of N-phosphorylamino acids as a model...
来源： cnki会议 评论
INVESTIGATION ON THE pEpTIDES FOrMATION FrOM AMINO ACIDS rEACTED WITH TrIMETApHOSpHATE BY LC-MS
INVESTIGATION ON THE PEPTIDES FORMATION FROM AMINO ACIDS REA...
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第17届国际磷化学大会
作者： Xiang Gao1 yan liu1 pengxiang Xu1 Guo Tang Yufen Zhao1 2* 1. The Key laboratory for {3. biology of Fujian province department of chemistry College of chemistry and {3. Engineering Xiamen university Xiamen 3.1005 p. r. china 2. The Key laboratory for bioorganic phosphorus chemistry Ministry of Education department of chemistry School of life Sciences and Engineering tsinghua university beijing 100084 p. r. china
＜正＞It was suggested that probably inorganic condensed phosphates, such as polyphosphate and trimetaphosphate, would have been the essential materials for the prebiotic evolution which preceded the emergence of life...
来源： cnki会议 评论
SYNTHESIS N-pHOSpHOrYLATED CHrYSIN-7-YL AMINO ACID ESTErS
SYNTHESIS N-PHOSPHORYLATED CHRYSIN-7-YL AMINO ACID ESTERS
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第17届国际磷化学大会
作者： li Wenfeng1 Chen Xiaolan1 Yuan Jinwei1 Qu lingbo1 2 Zhao Yufen1 3.1 department of chemistry Zhengzhou {3. Zhengzhou 450052 p. r. china 2 Anyang Normal College Henan province Anyang 455002 p. r. china 1 3.he Key laboratory for bioorganic phosphorus chemistry department of chemistry School life Sciences and Engineering tsinghua university beijing 10084 p. r. china
＜正＞Chrysin, 5,7-dihydroxyflavone, which is widely distributed in plants, is known to have many biological activities including antibacterial, antioxidant, anti-inflammatory, anti-allergic, anticancer,
来源： cnki会议 评论
pDK Inhibitor reverses BCrp-mediated Drug resistance
PDK Inhibitor Reverses BCRP-mediated Drug Resistance
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2011年全国药物化学学术会议——药物的源头创新
作者： li,Tian-Wen~1,SHANG,pei-Hua~1,CHENG,Chang-mei`(*,1),CHEN,Zhe-Sheng~(*,2),ZHAO,Yu-Fen~1 1 Key laboratory of {3. phosphorus chemistry & chemical biology(Ministry of Education),department of chemistry,tsinghua university,beijing,100084 2 department of pharmaceutical Sciences,College of pharmacy and Allied Health professions,St. John''s university,New York,NY 1143.
＜正＞（r）-l,l,l-trifluoro-2-hydroxy-2-methylpropanamides,represented by AZD7545,were known as pyruvate dehydrogenase kinase（pDK） inhibitor 1,***,it was reported that Mitapiatin, fusion of cisplatin and another pDK...
来源： cnki会议 评论
Novel and Convenient Method for the preparation of phosphonate peptides and phosphonamidate peptides
Novel and Convenient Method for the Preparation of Phosphona...
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第三届全国有机化学学术会议
作者： XU, Jia-Xi FU, Nan-yan GAO, Yuan-He ZHNAG, Qi-Han DUAN, li-Fang (Key laboratory of {3. chemistry and Molecular Engineering of Ministry of Education, department of chemical biology, College of chemistry and Molecular Engineering, peking university, beijing 100871, china)
＜正＞ phosphonate and phosphonamidate peptides are phosphorus analogues of natural peptides. They have been great used as stable mimetics of tetrahedral transition states as enzyme inhibitors and as haptens for catal...
来源： cnki会议 评论
Indole-3.acetic acid,a potential therapeutic target in Alzheimer's disease
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Science Bulletin 2024年 第2期69卷 146-147页
作者： Jinghong li department of chemistry Center for Bioanalytical ChemistryKey Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education)Tsinghua UniversityBeijing 100084China
Alzheimer's disease(AD)is a chronic and progressive neurodegenerative disease that is characterized by the presence of amyloid-β(Ap)plaques,hyperphosphorylated microtubule-associated tau protein(p-tau)neurofibrillary... 详细信息
来源： 维普期刊数据库 维普期刊数据库 评论
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