检索结果-南通市图书馆

血清14-3-3β蛋白联合呼出气一氧化氮及常规通气肺功能参数对儿童支气管哮喘的诊断效能

在线全文

学校读者我要写书评

暂无评论

中国当代儿科杂志 2024年第7期26卷 723-729页

作者：李舒芳郭广恩杨月琴熊晓曼郑世威谢雪丽张艳丽郑州大学第三附属医院儿科河南郑州450052

目的探讨血清14-3-3β蛋白联合呼出气一氧化氮(fractional exhaled nitric oxide,FeNO)及常规通气肺功能参数对儿童支气管哮喘(简称“哮喘”)的诊断效能。方法前瞻性纳入136例初次诊断为哮喘且处于急性发作期的儿童为哮喘组,选择同期85... 详细信息

目的探讨血清14-3-3β蛋白联合呼出气一氧化氮(fractional exhaled nitric oxide,FeNO)及常规通气肺功能参数对儿童支气管哮喘(简称“哮喘”)的诊断效能。方法前瞻性纳入136例初次诊断为哮喘且处于急性发作期的儿童为哮喘组,选择同期85例健康体检儿童为健康对照组,比较两组血清14-3-3β蛋白浓度的差异,分析血清14-3-3β蛋白与临床指标的相关性,评估14-3-3β蛋白联合FeNO及常规通气肺功能参数对儿童哮喘的诊断效能。结果哮喘组血清14-3-3β蛋白浓度高于健康对照组(P<0.001)。血清14-3-3β蛋白与中性粒细胞百分比、血清总免疫球蛋白E呈正相关,与常规通气肺功能参数呈负相关(P<0.05)。联合指标交叉验证显示14-3-3β蛋白+FeNO+用力呼出75%肺活量的呼气流量占预测值百分比预测哮喘的曲线下面积为0.948,灵敏度和特异度分别为88.9%和93.7%,具有较好的诊断效能(P<0.001),模型的外推性最好。结论血清14-3-3β蛋白联合FeNO、用力呼出75%肺活量的呼气流量占预测值百分比可以显著提高儿童哮喘的诊断效能。

关键词：支气管哮喘 14-3-3β蛋白联合诊断肺通气功能呼出气一氧化氮儿童

基于UHPLC-Q-Exactive Orbitrap HRMS技术结合化学计量学方法的不同干燥处理杜仲叶成分分析

在线全文

学校读者我要写书评

暂无评论

分析测试学报 2024年第2期43卷 213-225页

作者：李淑芳王会锋郝学飞胡永建李圆圆马风莲冯书惠杨亚琴于永杰河南省农业科学院农产品质量安全研究所河南郑州450002 宁夏医科大学药学院宁夏银川750004

采用基于液质联用的非靶向代谢组学技术结合化学计量学数据自动解析软件AntDAS-LCHRMS分析了4种不同干燥处理(冻干、热泵烘干、电热烘干、晒干)杜仲叶样本中的化合物。杜仲叶样本数据由超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UH... 详细信息

采用基于液质联用的非靶向代谢组学技术结合化学计量学数据自动解析软件AntDAS-LCHRMS分析了4种不同干燥处理(冻干、热泵烘干、电热烘干、晒干)杜仲叶样本中的化合物。杜仲叶样本数据由超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UHPLC-Q-Exactive Orbitrap HRMS)分别在正、负离子模式下进行采集,经AntDAS-LCHRMS软件解析,共鉴定出71种差异性化合物,经标准品验证确定40种化合物,包括环烯醚萜类、有机酸类、黄酮类、氨基酸类、核苷类、维生素类等9类物质。其中,正、负离子模式下均可识别并验证的化合物有车叶草苷、绿原酸、芦丁、异槲皮苷、车叶草苷酸、京尼平苷等25种化合物。层次聚类分析(HCA)及主成分分析(PCA)结果均显示,相同处理的杜仲叶样本各自聚成一类,不同处理的杜仲叶样本可明显区分。热图分析进一步揭示了不同干燥处理杜仲叶样本中差异性化合物的含量变化。晒干处理样本中苯丙氨酸及色氨酸等氨基酸类物质的水平较高;冻干及热泵烘干处理样本中有机酸类、环烯醚萜类、糖类等含量较高;电热烘干样本中核苷类、黄酮类物质的含量较高;黄酮类物质在冻干、热泵烘干及晒干样本中差异较小。研究结果为不同干燥处理杜仲叶的成分分析、品质评价及其开发应用提供了科学依据,也可为其他复杂药用植物体系的化学成分分析提供参考。

关键词：杜仲叶代谢组学化学计量学 AntDAS-LCHRMS软件超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UHPLC-Q-Exactive Orbitrap HRMS) 干燥处理

维普期刊数据库博看期刊

Novel error resilient tag estimation for RFID system in interference scenarios

在线全文

学校读者我要写书评

暂无评论

The Journal of China Universities of Posts and Telecommunications 2013年第4期20卷 116-121页

作者： WANG shuai HONG Wei-jun PENG Biao li shu-fang School of Information and Communication Engineering Beijing University of Posts and Telecommunications

In a radio frequency identification （RFID） system, the backscattered signal is small and prone to interference. The performance of RFID tag identification in interference scenarios is degraded compared to that in error-free scenarios. In this paper, a novel Mahalanobis distance estimate （MDE） method is proposed to jointly estimate the number of tags and packet error rate （PER）. The MDE method is error resilient owing to its ability to achieve a stable estimation when interference is impairing the observed information. The proposed method achieves significantly enhanced accuracy over existing methods by taking all the information and correlations among the observed results into account. The MDE method improves the estimate performance based on efficient decorrelation and classification of the observed information. Moreover, the performance of the PER estimate is analyzed both in theory and through simulations. It can be concluded from the analysis that the estimated PER is unbiased and variance-bounded. Simulations show that the proposed estimate outperforms the previous proposals in terms of accuracy and stability, which makes it suitable for application in interference scenarios.

关键词： RFID tag estimate PER estimate

在线全文

学校读者我要写书评

暂无评论

1490株血液标本分离细菌分布及其耐药性

中华医院感染学杂志 2024年第16期34卷 2417-2421页

作者：刘超梅李方舒周璐坤王振楠赵建平郭素芳联勤保障部队第969医院检验病理输血科内蒙古呼和浩特010051 内蒙古自治区人民医院检验科内蒙古呼和浩特010010 内蒙古医科大学附属医院检验科内蒙古呼和浩特010010

目的分析医院血培养分离菌的构成及耐药性,为临床血流感染的诊治提供参考。方法回顾性分析联勤保障部队第969医院2020年1月-2022年12月临床送检标本血培养阳性结果,参考美国临床和实验室标准化协会(CLSI)相应年份标准对药敏结果进行判... 详细信息

目的分析医院血培养分离菌的构成及耐药性,为临床血流感染的诊治提供参考。方法回顾性分析联勤保障部队第969医院2020年1月-2022年12月临床送检标本血培养阳性结果,参考美国临床和实验室标准化协会(CLSI)相应年份标准对药敏结果进行判读。结果共分离细菌1490株,革兰阳性菌756株(50.74%)、革兰阴性菌734株(49.26%);革兰阳性菌以凝固酶阴性葡萄球菌、屎肠球菌、金黄色葡萄球菌及粪肠球菌为主;革兰阴性菌以大肠埃希菌、马耳他布鲁菌、肺炎克雷伯菌及铜绿假单胞菌为主;儿童与成人血培养分离菌株的构成存在一定差异;耐甲氧西林金黄色葡萄球菌(MRSA)检出率低于耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)(P<0.05),葡萄球菌对替加环素、万古霉素及利奈唑胺100.00%敏感;屎肠球菌对万古霉素的耐药率为1.92%;大肠埃希菌产超广谱β-内酰胺酶(ESBLs)株检出率高于肺炎克雷伯菌产ESBLs株(P<0.05);肺炎克雷伯菌对亚胺培南、美罗培南耐药率分别为11.61%、12.50%;铜绿假单胞菌对大多数抗菌药物耐药率<15%。结论血培养分离细菌种类较多,且耐药形势严重,应加强血流感染病原学监测,为临床合理用药提供依据。

关键词：血培养血流感染细菌不同年龄组抗菌药物耐药性

在线全文

学校读者我要写书评

暂无评论

青年人群前磨牙牙髓血流灌注量研究

牙体牙髓牙周病学杂志 2024年第4期29卷 200-205页

作者：黄晓凤胡玉萍李娇娇韦方圆黎淑芳右江民族医学口腔医学院广西百色533000 钦州市第一人民医院广西钦州535099

目的:应用激光多普勒血流仪(LDF)检测青年人群的前磨牙牙髓血流灌注量(PBF),统计分析青年人群前磨牙生理状态下PBF参考值范围,探讨年龄、性别、牙位对PBF的影响。方法:在右江民族医学院、百色学院两所高校的在校生及就诊于右江民族医学... 详细信息

目的:应用激光多普勒血流仪(LDF)检测青年人群的前磨牙牙髓血流灌注量(PBF),统计分析青年人群前磨牙生理状态下PBF参考值范围,探讨年龄、性别、牙位对PBF的影响。方法:在右江民族医学院、百色学院两所高校的在校生及就诊于右江民族医学院附属医院口腔科的患者招募150名志愿者。使用LDF进行前磨牙PBF值检测,硅橡胶印模材料将LDF探头垂直固定于前磨牙颊侧中线距龈缘2~3 mm的待检测区域,进行检测及记录检测结果,并讨论影响PBF的相关因素。结果:(1)健康人群前磨牙PBF参考值范围:男性上颌第一前磨牙:(10.19±4.28)PU;上颌第二前磨牙:(11.29±4.33)PU;下颌第一前磨牙(10.07±4.63)PU;下颌第二前磨牙(10.67±4.39)PU。女性:上颌第一前磨牙(10.20±4.68)PU;上颌第二前磨牙(10.57±4.22)PU;下颌第一前磨牙(9.46±4.15)PU;下颌第二前磨牙(10.35±4.78)PU。(2)上颌前磨牙PBF值较下颌同名前磨牙PBF值高,差异有统计学意义(P0.05)。(5)25、44PBF值存在性别差异(P0.05)。结论:青年人群上颌前磨牙的PBF值较下颌前磨牙的PBF值高,第二前磨牙的PBF值较同颌第一前磨牙血流值高,同颌同名前磨牙PBF值不存在差异,可作为对照牙选择。

关键词：激光多普勒血流仪前磨牙牙髓血流灌注量

Quantitative spectrum occupancy evaluation in China: based on a large scale concurrent spectrum measurement

在线全文

学校读者我要写书评

暂无评论

The Journal of China Universities of Posts and Telecommunications 2012年第3期19卷 122-128页

作者： YIN liang YIN Si-xing WANG shuai ZHANG Er-qing HONG Wei-jun li shu-fang School of Information and Communication Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China

Due to the usable frequency becomes more and more crowed, dynamic spectrum access （DSA） is a new hope to solve this problem. However, DSA in China requires a quantitative analysis of the current spectrum utilization in frequency, temporal and spatial domains. In order to free the precious spectrum, spectrum regulation organizations must have a clear, detailed, up-to-date understanding of where, how and by whom spectrum is currently being used--such data is essential to sound policy decisions in the context of cognitive radio （CR）. In this paper, a concurrent spectrum occupancy measurement in south China was conducted to evaluate the practical spectrum occupancy with a digital wideband receiver covering from 20 MHz to 3 GHz. We also propose systemic spectrum measurement methodology, matrix format data storage, duty cycle （DC） evaluation metric and data mining process which can be a guideline for other researchers when they conduct the similar experiments. Quantitative analysis and characterization of the 4 different measurement locations are evaluated to promote the popularization of CR application in China. And a uniform Beta distribution channel occupancy model is also validated using real-scene measurement data. The experimental results demonstrate that there is a significant scope for license-exemption use of the released spectrum using CR technology.

关键词： cognitive radio spectrum measurement spectrum occupancy duty cycle Beta distribution

不同周龄和性别的SPF级SD大鼠血液生理生化指标的测定与比较分析

在线全文

学校读者我要写书评

暂无评论

实验室检测

实验室检测 2024年第1期2卷 23-29页

作者：王婧荃郭学莉郭婷婷郭剑平李曙芳中国辐射防护研究院太原030000

目的探讨分析不同周龄和性别的SPF级SD大鼠血液生理生化指标。方法研究对象为SPF级SD大鼠80只,并随机将其分为4、12、24、48周龄4个实验组,每组内雌雄比例为1:1,所有SD大鼠均应用XFA6030型动物血液细胞分析仪对其血液生理指标展开分析,... 详细信息

目的探讨分析不同周龄和性别的SPF级SD大鼠血液生理生化指标。方法研究对象为SPF级SD大鼠80只,并随机将其分为4、12、24、48周龄4个实验组,每组内雌雄比例为1:1,所有SD大鼠均应用XFA6030型动物血液细胞分析仪对其血液生理指标展开分析,应用Beckman Coulter AU5800全自动生化分析仪对其血液生化指标展开分析。结果与12、24、48周龄SD大鼠相比较,4周龄的SD大鼠在WBC、RBC、HGB、HCT、MCV、MCH、MCHC、PLT、PCT、BA#、BA%几方面具有较大差异,P<0.05,且各项指标达到峰值的时间均为24周,在雌雄的性别差异中,4周龄SD大鼠BA%具有差异;12、24周龄SD大鼠WBC、RBC具有差异;24周龄SD大鼠BA%具有差异;48周龄SD大鼠MCH、PCT具有差异,且所有差异P值均<0.05;与12、24、48周龄SD大鼠相比较,4周龄的SD大鼠在AST、CHOL、TP、GLU、CRE、ALT、ALP、BUN、TG几方面具有较大差异,P<0.05,在雌雄的性别差异中,4周龄SD大鼠CRE、ALP见具有差异;12周龄SD大鼠AST、CHOL、BUN具有差异;12周龄以及24周龄SD大鼠ALP具有差异,且所有差异P值均<0.05。结论在性别相同但周龄不同的SD大鼠中,其血液生理生化指标存在统计学差异,同样的,在同周龄但不同性别的SD大鼠中亦存在差异。

关键词： SPF级SD大鼠血液生理指标生化指标周龄雌雄

Relationship between clinical belonging,professional identity,and nursing information ability among nursing interns:Model construction

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第13期12卷 2210-2217页

作者： Gai Zhang Shao-Juan Huang shu-fang li Department of Nursing Foshan Hospital of Traditional Chinese MedicineFoshan 528000Guangdong ProvinceChina

BACKGROUND Clinical belonging refers to the feeling that clinical medical staff feel recognized and accepted by others or *** level of clinical belonging of nursing interns affects students’learning motivation and confidence,which in turn affects their clinical practice *** To explore the effects of professional identity and nursing information ability on clinical belonging among nursing interns and establish a relationship model for these *** The researchers used the convenience sampling method to select 682 nursing interns from *** survey was conducted using a general information questionnaire,clinical sense of belonging scale,nursing information ability self-assessment scale,and a nursing student professional identity *** mediating effect of nursing information ability between their professional identity and clinical sense of belonging was analyzed using SPSS 21.0 and the path analysis in structural equation *** The total scores of clinical belonging,professional identity,and nursing information ability of nursing interns were(104.29±13.11)points,(57.89±7.16)points,and(70.29±6.20)points,*** information ability had a direct effect on the clinical sense of belonging(effect value=0.46,Plinical *** Nursing administrators in nursing colleges and hospitals should take effective measures to improve the professional identity and nursing information ability of nursing interns,as well as the clinical sense of belonging among nursing interns.

关键词： Belongingness Nursing Education Undergraduate Information literacy Models

Risk Factors And Outcome of Pancreatic Fistula after Consecutive Pancreaticoduodenectomy with Pancreaticojejunostomy for Patients with Malignant Tumor

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Cancer Research 2010年第1期22卷 32-41页

作者： Wei-hua Zhu shu li Da-fang Zhang Ji-run Peng Zhong-tian Jin Guang-ming li Fu-shun Wang Ji-ye Zhu Xi-sheng Leng Department of Hepatobiliary surgery Peiking University People＇s Hospital Beijing 100044 China

Objective： Pancreatic fistula （PF） is a common complication after pancreaticoduodenectomy （PD） and there is no consensus regarding the criteria to define PF. The study was undertaken to determine the risk factors for PF according to the definition of the International Study Group on Pancreatic Fistula （ISGPF） and to delineate its impact on patient outcome. Methods： Between March 1994 and May 2009, data from 153 consecutive patients with malignant tumors underwent a PD with pancreaticojejunostomy in the Peking University People＇s Hospital were recorded prospectively A total of 24 factors were examined with univariate analysis and multivariate logistic regression analysis was used to estimate relative risks, and their 95% confidence intervals （95% CI） and odds ratio （OR）. Results： Our institution belonged to medium-volume center and PF occurred in 30 patients （19.6%）. Pancreatic texture, early postoperative hemorrhage and pancreatic pathologies correlated with PF rates significantly in univariate analyses. But in multivariate regression, soft gland （OR, 4.934; 95% CI, 1.132-7.312） and early postoperative hemorrhage with conservative therapy （OR, 4.130; 95% CI, 1.057-21.112） were predictive. The mean postoperative length of stay in patients with PF was longer （32.7±23.9 versus 60.5±56.2 days） than patients without PF （P=0.001）. Overall 30-day mortality was not affected by the development of PF （P=0.657）. There was no difference in reoperation rates between patients with and without PF （10.0% versus 6.5%, P=0.787）. Concerning the sum of postoperative complications, there were 36 complications for 30 patients with PF, while 64 for 123 patients without PF. When patients with distal cholangiocarcinoma, ampullary and duodenal cancer were considered as a whole for survival analysis, the median survival for patients with PF was 20 months, whereas the median survival for patients without PF was 26 months. Kaplan-Meier survival curves for patients with and without PF were not

关键词： Pancreatieoduodenectomy Pancreatic fistula Morbidity Mortality Surgical outcome