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Nontrivial homoclinic orbits for second-order singular and periodic Hamiltonian systems

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Chinese Science Bulletin 1999年第2期44卷 123-129页

作者： li Chengyue , fan tianyou TONG MingshengResearch Center of Materials Science, beijing institute of technology, beijing 100081, china department of Mathematics, Central University for Nationalities, beijing 100081, china Computer Center, beijing institute of technology, beijing 100081, china Research Center of Materials Science Beijing Institute of Technology Beijing China department of Mathematics Central University for Nationalities Beijing China Computer Center Beijing Institute of Technology Beijing China

The existence of nontrivial homoclinic orbits of periodic Hamiltonian systems: is proved, where q=（q1,q2,’',qn）, n>2; V（t, q）:R1×Rn\{e}→R1 is a potential With a singularity, i.e. -V（t, q）→+∞, as q→e. The m... 详细信息

关键词： Hamiltonian systems strong force condition homoclinic orbit.

Holographic superfluid ring with a weak link

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Science china(physics,Mechanics & Astronomy) 2024年第11期67卷 29-38页

作者： Zhi-Hong li Huai-fan li department of physics Shanxi Datong UniversityDatong 037009China institute of Theoretical physics Shanxi Datong UniversityDatong 037009China

We explore the generation of topological defects in the course of a dynamical phase transition in a ring with a weak link, i.e., a SSS Josephson junction, from the AdS/CFT correspondence. By setting different parameters of the junction(width, steepness,depth) and the final temperature of the quench, the configurations of the charge density and condensate of the order parameters of the dual field theory are presented. Meanwhile, we observe that in the final equilibrium state, variations in parameters of the junctions only affect the configurations of the charge density and condensate of the order parameters, without altering their values outside the junction. However, variations in the final temperature will directly affect the values of the charge density and condensate of the order parameters outside of the junction. Moreover, in the final equilibrium state, we propose an analytic relation between the gauge-invariant velocity in the two superconducting states in the SSS Josephson junction, which agrees well with the numerical results.

关键词： AdS/CFT correspondence holographic superfluid holographic Josephson junction

Molecular phylogeny of Pneumocystis based on 5.8S rRNA gene and the internal transcribed spacers of rRNA gene sequences

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Science china(life Sciences) 2008年第5期51卷 445-452页

作者： li ZiHui1,2, FENG XianMin1, LU SiQi1, ZHANG fan1, WANG FengYun1 & HUANG Song1 1 department of Pathogenic Biology, Capital Medical University, beijing 100069, china 2 beijing Tuberculosis and Thoracic Tumor Research institute, beijing 101100, china department of Pathogenic Biology Capital Medical University Beijing China beijing Tuberculosis and Thoracic Tumor Research institute Beijing China

To clarify the phylogenetic relationships and species status of Pneumocystis, the 5.8S rRNA gene and the internal transcribed spacers (ITS, 1 and 2) of Pneumocystis rRNA derived from rat, gerbil and human were amplified, cloned and sequenced. The genetic distance matrix of six Pneumocystis species compared with other fungi like Taphrina and Saccharomyces indicated that the Pneumocystis genus contained multiple species including Pneumocystis from gerbil. The phylogenetic tree also showed that Pneumocystis from human and monkey formed one group and four rodent Pneumocystis formed another group. Among the four members, Pneumocystis wakefieldiae was most closely related to Pneumocystis murina and Pneumocystis carinii, and was least related to gerbil Pneumocystis.

关键词： Pneumocystis phylogeny 5.8S rRNA gene internal transcribed spacers

Anomalies of Precipitation over china on Days with Tropical Cyclone Activity over the Bay of Bengal: Role of Moisture Transport

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Journal of Meteorological Research 2024年第2期38卷 368-382页

作者： Na WEI Ying li Xiaoting fan Nanjing Joint institute for Atmospheric Sciences Nanjing 210041 State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081 department of Atmospheric and Oceanic Sciences and institute of Atmospheric Sciences Fudan UniversityShanghai 200433

Tropical cyclones over the Bay of Bengal(BoBTC)affect the precipitation over china,with distinct seasonal and daily *** study quantitatively examines the daily standardized precipitation anomalies(SPAs)over china on the days with BoBTC activities(storm-days)and related circulations,based on rainfall measurements at surface meteorological stations and ECMWF reanalysis data on a 0.25°×0.25°resolution during *** positive SPA is found over the stations in the two adjacent regions around BoB(Southwest china in May/November and southern Tibetan Plateau in October)and three distant regions(Southeast china and the northeastern boundary of the Qinghai-Tibet Plateau in May,and central North china in October).The SPA distributions are remarkably consistent with the integrated water vapor transport(IVT)*** IVT is found associated with the interaction between southwesterly(southerly)of the BoBTC circulation and low-level monsoonal flow in May(midlevel westerly in winter months).The probabilities of extreme precipitation(EP)occurrences over the above regions all increase on *** adjacent regions,EP is significantly correlated with the northward IVT anomalies to the east of BoBTC circulation,which strengthen the water vapor input through the southern *** IVT anomalies are stronger in May,benefited by the deep monsoonal southwesterlies than those in *** distant regions,EP is more closely related to the IVT anomaly extending back from *** moisture from BoB concentrates along a local low-level convergence line over Southeast china,being further facilitated by coexistence of the BoBTC depression and midlevel westerly trough in *** results highlight the interactions between BoBTCs and local weather systems that influence the general precipitation anomalies and occurrence of EP over china,especially over distant regions.

关键词： tropical cyclone Bay of Bengal precipitation anomaly moisture transport

Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies

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Genes & Diseases 2024年第5期11卷 315-323页

作者： Jiankun fan Zhigang li li Pei Yu Hou institute of life Sciences Chongqing Medical UniversityChongqing 400016China department of Hematology Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China

Hematopoiesis represents a meticulously regulated and dynamic biological *** aberrations affecting blood cells,induced by various factors,frequently give rise to hematological *** instances are often accompanied by a multitude of abnormal post-transcriptional regulatory events,including RNA alternative splicing,RNA localization,RNA degradation,and ***,post-transcriptional regulation plays a pivotal role in preserving hematopoietic *** DEAD-Box RNA helicase genes emerge as crucial post-transcriptional regulatory factors,intricately involved in sustaining normal hematopoiesis through diverse mechanisms such as RNA alternative splicing,RNA modification,and ribosome *** review consolidates the existing knowledge on the role of DEAD-box RNA helicases in regulating normal hematopoiesis and underscores the pathogenicity of mutant DEADBox RNA helicases in malignant *** is placed on elucidating both the positive and negative contributions of DEAD-box RNA helicases within the hematopoietic system.

关键词： DEAD-box RNA helicase Hemopoietic system Post-transcriptional regulation Ribosomes assembly RNA alternative splicing

Bioinspired metal-organic framework nanozyme reinforced with thermosensitive hydrogel for regulating inflammatory responses in Parkinson’s disease

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Nano Research 2024年第2期17卷 858-865页

作者： Xiaowan fan Tao Zhang Xin Ding Yushuo Gu Qing li Wei Jiang Kelong fan Nanozyme Medical Center Academy of Medical ScienceZhengzhou UniversityZhengzhou 450001China department Central-China Branch of National Center for Cardiovascular DiseasesHean Cardiovascular Disease CenterFuwai Central-China HospitalCentral China Fuwai Hospital of Zhengzhou UniversityZhengzhou 450046China Application Center for Precision Medicine the Second Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China CAS Engineering Laboratory for Nanozyme Key Laboratory of Protein and Peptide PharmaceuticalsInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 101408China department of General Surgery Strategic Support Force Medical CenterBeijing 100101China department of Anesthesiology Pain and Perioperative MedicineThe First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China

Parkinson’s disease(PD)is a prevalent neurodegenerative disorder accompanied by movement disorders and neuroinflammatory ***-inflammatory intervention to regulate oxidative stress in the brain is beneficial for managing ***,traditional natural antioxidants have failed to meet the clinical treatment demands due to insufficient activity and ***,Cu-doping zeolite imidazolate framework-8(ZIF-8)nanozyme is designed to simulate Cu/Zn superoxide dismutase(SOD)by biomimetic *** nanozyme composite is then integrated into thermosensitive hydrogel(poly(lactic-co-glycolic acid)-poly(ethylene glycol)-poly(lactic-co-glycolic acid)(PLGA-PEG-PLGA))to form an effective antioxidant system(Cu-ZIF@Hydrogel).The thermosensitive hydrogel incorporating nanozymes demonstrate distinct viscoelastic properties aimed at enhancing local nanozyme adhesion,prolonging nanozyme retention time,and modulating antioxidant activity,thus significantly improving the bioavailability of *** the cellular and animal levels of PD,we find that Cu-ZIF@Hydrogel bypass the blood-brain barrier and efficiently accumulate in the nerve ***,the Cu-ZIF@Hydrogel significantly alleviate the PD’s behavioral and pathological symptoms by reducing the neuroinflammatory levels in the lesion ***,the hydrogel-incorporating nanozyme system holds great potential as a simple and reliable avenue for managing PD.

关键词： bioinspired nanozyme thermosensitive hydrogel Parkinson’s disease oxidative stress neuroinflammatory

Monogamy and polygamy for the generalized W-class states using unified-(q,s)entropy

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Science china(physics,Mechanics & Astronomy) 2024年第1期67卷 10-22页

作者： Bo li Bing Xie Zhanjun Zhang Heng fan School of Computer and Computing Science Hangzhou City UniversityHangzhou 310015China department of Mathematics East China University of TechnologyNanchang 330013China School of Information&Electronic Engineering(Sussex Artificial Intelligence institute) Zhejiang Gongshang UniversityHangzhou 310018China institute of physics Chinese Academy of SciencesBeijing 100190China

We describe the entanglement distribution and restricted shareability of the multipartite generalized W-class states and their reduced density matrix under arbitrary partitions by using monogamy and polygamy relation based on the unified-(q,s)***,we provide an analytical formula of unified-(q,s)entanglement(UE)and an analytical lower bound of unified-(q,s)entanglement of assistance(UEo A)for a reduced density matrix of a generalized W-class ***,we use these two analytical formulas to derive the monogamy and polygamy inequalities for a reduced density matrix of a qudit generalized W-class(GW)*** establish two partition-dependent residual entanglements based on the new monogamy relation,which is helpful to obtain a comprehensive analysis of entanglement dynamics of generalized W-class ***,we investigate tighter monogamy and polygamy relations based on the power ofαth(α≥0)for UE andβth(β≥0)for UEo A,*** results show that the entanglement distribution characteristics of generalized W-class states satisfying stronger constraints can be described more accurately.

关键词： monogamy polygamy multiqudit unified entropy

Application of GNSS-PPP on Dynamic Deformation Monitoring of Offshore Platforms

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china Ocean Engineering 2024年第2期38卷 352-361页

作者： YU li-na XIONG Kuan GAO Xi-feng li Zhi fan li-long ZHANG Kai institute of Ocean Energy and Intelligent Construction Tianjin University of TechnologyTianjin 300384China china Railway Construction Bridge Engineering Bureau Group Co.LTD Tianjin 300300China School of Civil Engineering Tianjin UniversityTianjin 300072China department of Land Surveying and Geo-Informatics The Hong Kong Polytechnic UniversityHong KongChina State Key Laboratory of Precision Blasting Jianghan UniversityWuhan 430056China

The real-time dynamic deformation monitoring of offshore platforms under environmental excitation is crucial to their safe *** Global Navigation Satellite System-Precise Point Positioning(GNSS-PPP)has been considered for this purpose,its monitoring accuracy is relatively ***,the influence of background noise on the dynamic monitoring accuracy of GNSS-PPP remains ***,it is imperative to further validate the feasibility of GNSS-PPP for deformation monitoring of offshore *** address these concerns,vibration table tests with different amplitudes and frequencies are *** results demonstrate that GNSS-PPP can effectively monitor horizontal vibration displacement as low as±30 mm,which is consistent with ***,the spectral characteristic of background noise in GNSS-PPP is similar to that of GNSS-RTK(Real Time Kinematic).Building on this observation,an improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise(CEEMDAN)has been proposed to de-noise the data and enhance the dynamic monitoring accuracy of *** monitoring application research is also undertaken,successfully extracting and analyzing the dynamic deformation of an offshore platform structure under environmental excitation using GNSS-PPP monitoring in conjunction with improved CEEMDAN *** comparing the de-noised dynamic deformation trajectories of the offshore platform during different periods,it is observed that the platform exhibits reversible alternating vibration responses under environmental excitation,with more pronounced displacement deformation in the direction of load *** research results confirm the feasibility and potential of GNSS-PPP for dynamic deformation monitoring of offshore platforms.

关键词： GNSS-PPP offshore platform dynamic deformation monitoring improved CEEMDAN de-noising

Artificial selection of the Green Revolution gene Semidwarf 1 is implicated in upland rice breeding

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Journal of Integrative Agriculture 2024年第3期23卷 769-780页

作者： Shuliang Jiao Qinyan li fan Zhang Yonghong Tao Yingzhen Yu fan Yao Qingmao li Fengyi Hu liyu Huang Key Laboratory of Biology and Germplasm Innovation of Perennial Rice Ministry of Agriculture and Rural Affairs/School of AgricultureYunnan UniversityKunming 650091China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Wenshan Academy of Agricultural Sciences Wenshan 663000China

Semidwarf breeding has boosted crop production and is a well-known outcome from the first Green Revolution. The Green Revolution gene Semidwarf 1(SD1), which modulates gibberellic acid(GA) biosynthesis, plays a principal role in determining rice plant height. Mutations in SD1 reduce rice plant height and promote lodging resistance and fertilizer tolerance to increase grain production. The plant height mediated by SD1 also favors grain yield under certain conditions. However, it is not yet known whether the function of SD1 in upland rice promotes adaptation and grain production. In this study, the plant height and grain yield of irrigated and upland rice were comparatively analyzed under paddy and dryland conditions. In response to dryland environments, rice requires a reduction in plant height to cope with water deficits. Upland rice accessions had greater plant heights than their irrigated counterparts under both paddy and dryland conditions, and appropriately reducing plant height could improve adaptability to dryland environments and maintain high grain yield formation. Moreover, upland rice cultivars with thicker stem diameters had stronger lodging resistance, which addresses the lodging problem. Knockout of SD1 in the upland rice cultivar IRAT104 reduced the plant height and grain yield, demonstrating that the adjustment of plant height mediated by SD1 could increase grain production in dryland fields. In addition, an SD1 genetic diversity analysis verified that haplotype variation causes phenotypic variation in plant height. During the breeding history of rice, SD1 allelic mutations were selected from landraces to improve the grain yield of irrigated rice cultivars, and this selection was accompanied by a reduction in plant height. Thus, five known mutant alleles were analyzed to verify that functional SD1 is required for upland rice production. All these results suggest that SD1 might have undergone artificial positive selection in upland rice, which provides

关键词： Green Revolution Semidwarf 1 high-yield breeding upland rice plant height