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Food Science and Human Wellness 2024年第5期13卷 2718-2726页

作者： Xue li Yiwen Shao limin Hao Qiaozhen Kang Xiaolong Wang jiaqing Zhu Changcheng Zhao Yanling Shi Jike Lu Juanjuan Yi School of life Sciences Zhengzhou UniversityZhengzhou 450001China Food Laboratory of Zhongyuan Zhengzhou UniversityLuohe 462300China Systems Engineering Institute Academy of Military Sciences(AMS)Beijing 100010China Henan Yinfeng Biological Engineering Technology Co. Ltd.Zhengzhou 450000China

Chinese yam(Dioscorea opposita Thunb.),as one of the medicinal and edible homologous plants,is rich in various nutrients and functional *** this study,Chinese yam fermented by Saccharomyces boulardii was performed to investigate its bioactive components and metabolic *** then,the main bioactive components and biological activities of fermented Chinese yam ethanol extract(FCYE)were *** showed that there were 49 up-regulated metabolites and 52 down-regulated metabolites in fermented Chinese yam compared to unfermented Chinese ***,corresponding metabolic pathways analysis initially revealed that the distribution of bioactive substances was concentrated on alcoholsoluble small molecular ***,the total polyphenol content and the total flavonoid content in FCYE were significantly increased,and the corresponding antioxidant and immunomodulatory activities in vitro were also significantly *** study provided a new reference for the comprehensive utilization of Chinese yam and laid a theoretical foundation for the development and application of natural probiotic-fermented products.

关键词： Chinese yam Saccharomyces boulardii Metabolites Antioxidant Immunomodulation

Chromosome-level genome and population genomics of the intermediate horseshoe bat(Rhinolophus affinis)reveal the molecular basis of virus tolerance in Rhinolophus and echolocation call frequency variation

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Zoological Research 2024年第5期45卷 1147-1160页

作者： Le Zhao jiaqing Yuan Guiqiang Wang Haohao Jing Chen Huang Lulu Xu Xiao Xu Ting Sun Wu Chen Xiuguang Mao Gang li College of life Sciences Shaanxi Normal UniversityXi’anShaanxi 710119China Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C. School of Bioscience and EngineeringShaanxi University of TechnologyHanzhongShaanxi 723001China Guangzhou Zoo GuangzhouGuangdong 510070China School of Ecological and Environmental Sciences East China Normal UniversityShanghai 200241China

Horseshoe bats(genus Rhinolophus,family Rhinolophidae)represent an important group within chiropteran phylogeny due to their distinctive traits,including constant high-frequency echolocation,rapid karyotype evolution,and unique immune *** in evolutionary biology,supported by high-quality reference genomes and comprehensive whole-genome data,have significantly enhanced our understanding of species origins,speciation mechanisms,adaptive evolutionary processes,and phenotypic ***,genomic research and understanding of the evolutionary patterns of Rhinolophus are severely constrained by limited data,with only a single published genome of *** currently *** this study,we constructed a high-quality chromosome-level reference genome for the intermediate horseshoe bat(***).Comparative genomic analyses revealed potential genetic characteristics associated with virus tolerance in ***,we observed expansions in several immune-related gene families and identified various genes functionally associated with the SARS-CoV-2 signaling pathway,DNA repair,and apoptosis,which displayed signs of rapid *** addition,we observed an expansion of the major histocompatibility complex class II(MHC-II)region and a higher copy number of the HLA-DQB2 gene in horseshoe bats compared to other chiropteran *** on whole-genome resequencing and population genomic analyses,we identified multiple candidate loci(e.g.,Gli3)associated with variations in echolocation call frequency across *** *** research not only expands our understanding of the genetic characteristics of the Rhinolophus genus but also establishes a valuable foundation for future research.

关键词： Reference-quality genome Comparative genomics Population genomics Positive selection Bats

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机械噪声源识别的混合波叠加法

中国机械工程 2006年第23期17卷 2503-2507页

作者：薛玮飞陈进李加庆上海交通大学振动冲击噪声国家重点实验室上海200240

提出了一种稳健声场的全息变换算法———混合波叠加法,它结合了波叠加法和Helm-holtz方程最小二乘(HELS)方法的优点,用相对少量的测点数据就可重建任意形状源表面的声场。在半消声室里,运用29个传声器组成的“+”字形平面传声器阵列,... 详细信息

提出了一种稳健声场的全息变换算法———混合波叠加法,它结合了波叠加法和Helm-holtz方程最小二乘(HELS)方法的优点,用相对少量的测点数据就可重建任意形状源表面的声场。在半消声室里,运用29个传声器组成的“+”字形平面传声器阵列,对一运转的电机进行噪声源识别,得到声源的空间声压场分布及声源位置,显示出混合波叠加法在工程实践中广泛的应用前景。

关键词：混合波叠加法声源识别声场重建 HELS

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基于声全息的故障诊断方法

机械工程学报 2009年第5期45卷 34-38页

作者：李加庆陈进史重九上海机动车检测中心上海201805 上海交通大学机械系统与振动国家重点实验室上海200240

基于振动信号的故障诊断方法在某些场合下存在着局限性。机械噪声蕴含着丰富的设备状态信息,而且具有非接触式测量的优点,可以部分地替代振动信号,用于故障诊断。传统的噪声诊断方法主要基于频谱分析,无法反映声源位置和强度的变化信息... 详细信息

基于振动信号的故障诊断方法在某些场合下存在着局限性。机械噪声蕴含着丰富的设备状态信息,而且具有非接触式测量的优点,可以部分地替代振动信号,用于故障诊断。传统的噪声诊断方法主要基于频谱分析,无法反映声源位置和强度的变化信息,只能进行初步的故障诊断。基于此,提出一种基于声全息的故障诊断方法。该方法采用由少量传声器组成的阵列测量声压,应用波叠加法重构物体的外部声场,可以方便快速地进行声场可视化。一旦准确地重建出物体的外部声场,就可以利用这些全息场的信息进行故障诊断。通过建立基于全息图的正常状态与故障状态的模板,将机器的运行信息与这些模板对比,就可以判定机器的运行状态,从而进行故障诊断。采用由多个脉动球组成的声源模型进行了数值仿真,并在消声室内对两只音箱噪声源进行了试验研究,都准确地识别出辐射体声场状态变化,找出了故障。从而验证了该方法的正确性和实用性,为其在现场应用打下基础。

关键词：故障诊断特征提取声全息波叠加法

三江中段铜多金属矿床流体成矿作用:微量元素地球化学证据

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岩石学报 2016年第3期32卷 804-814页

作者：宋昊张成江李佑国钟文丽李家庆成都理工大学成都610059 四川省地学核技术重点实验室成都610059 四川省地矿局川西北地质队绵阳621000

研究区属"三江成矿带"中段,包含三个不同的地质构造单元,由西向东依次为金沙江混杂岩带、中咱地块、义敦岛弧带。本文通过对这三个构造单元中代表性铜多金属矿床中热液石英脉进行系统的采样和微量稀土元素分析,讨论了各构造单元中石英... 详细信息

研究区属"三江成矿带"中段,包含三个不同的地质构造单元,由西向东依次为金沙江混杂岩带、中咱地块、义敦岛弧带。本文通过对这三个构造单元中代表性铜多金属矿床中热液石英脉进行系统的采样和微量稀土元素分析,讨论了各构造单元中石英脉的微量及稀土元素地球化学特征及分布模式,在此基础上结合研究区的地质背景及演化,进一步讨论石英脉中微量元素的指示意义。结果表明:1)研究区石英脉中Cu、Zn等成矿元素与亲岩浆元素呈较好正相关,指示成矿与岩浆活动的联系,微量元素地球化学特征指示中咱地块成矿流体与岩浆活动的联系较为密切;2)中咱地块石英脉稀土元素地球化学特征与义敦岛弧带和金沙江混杂岩带成矿流体差异较大,中咱地块流体稀土元素接近于地幔的稀土组成特征,稀土元素配分曲线为近于水平的平缓曲线,稀土元素特征参数表明形成于相对还原的环境,反映出深部来源很可能是中咱地块成矿流体的主要物质来源;3)石英微量元素地球化学特征的研究为本区区域构造演化提供了佐证,金沙江混杂岩带和义敦岛弧带的成矿流体特征较为相似,而在中咱地块与扬子陆块夹持间形成的义敦岛弧带成矿流体与中咱地块存在较大的元素地球化学差异。本文通过对石英的微量元素、稀土元素地球化学特征的研究为该区的区域成矿特征、热液流体成因和构造演化提供了证据,并对西南三江地区的找矿理论提出了建议。

关键词：石英脉成矿流体微量稀土元素地球化学示踪铜多金属矿床三江中段

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我国资源共享网络的障碍及其对策

图书情报工作 1999年第11期43卷 35-37页

作者：李家清重庆商学院重庆400067

简述我国资源共享网络的现状 ,剖析资源共享网络存在的障碍 ,提出解决障碍的具体对策。

关键词：信息资源资源共享网络障碍对策中国

Operation Status of LAPECR3 Ion Source in 2017

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IMP & HIRFL Annual Report 2017年第1期 253-255页

作者： Cao Yun li jiaqing Jin Gang liu Wenzhou Guo Xupeng li Cong Zhang Xuezhen Wang Hui Guo Junwei 不详

Lanzhou All Permanent Electron Cyclotron Resonance ion source no.3(LAPECR3)has been developed for Heavy Ion Medical Machine(HIMM)accelerator facility since 2009 year[1].The first HIMM accelerator facility was built in Wuwei *** the HIMM accelerator facility extracted C6+ion beam successfully in December 2015,many equipment tests and beam optimization had been carried ***,the main task of LAPECR3 ion source is routine operation in the last two *** are two LAPECR3 ion sources at the HIMM accelerator facility in Wuwei,and only one of the ion source is operated while the other is on *** layout of the ion sources is shown in Fig.1.

关键词： ECR beam source

Prevalence and risk factors of atopic dermatitis in Chinese adults: a nationwide population-based cross-sectional study

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Chinese Medical Journal 2023年第5期136卷 604-606页

作者： Dandan Mao jiaqing li Shuoshuo liu Ping liu Jing Tian Xiaojing liu Ruiqun Qi Bingxue Bai Yu Wang Jianzhong Zhang Department of Dermatology Peking University People’s HospitalBeijing 100044China Department of Dermatology Beijing Children’s HospitalCapital Medical UniversityBeijing 100045China Department of Phototherapy at Shanghai Skin Disease Hospital School of MedicineTongji UniversityShanghai 200443China Department of Dermatology The First Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Dermatology Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150001China Department of Dermatology Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou 550004China.

Atopic dermatitis(AD),also known as atopic eczema,eczema,endogenous eczema,and neurodermatitis,is a chronic inflammatory skin disease occurring in children,adolescents,and *** with AD often have severe itching and may have other atopic diseases(e.g.,allergic rhinitis,asthma,or allergic conjunctivitis).AD has a profound impact on patients’quality of *** prevalence of AD in Chinese children has been reported.[1]However,no large-scale population-based study has focused on the prevalence of AD in Chinese *** present nationwide survey was conducted to investigate the prevalence and risk factors of AD in Chinese adults.

关键词： dermatitis allergic prevalence

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巨噬细胞极化与AMD的关系

中华实验眼科杂志 2016年第1期34卷 89-91页

作者：刘芳李加青丁小燕广州中山大学中山眼科中心 510060

年龄相关性黄斑变性（AMD）是世界范围内老年人群中主要的致盲原因之一。巨噬细胞在AMD的致病机制中有重要作用，随着病程的发展，巨噬细胞根据微环境的变化转化为经典活化的M1型或选择性活化的M2型。在AMD进程中，M1／M2失衡可能是造... 详细信息

年龄相关性黄斑变性（AMD）是世界范围内老年人群中主要的致盲原因之一。巨噬细胞在AMD的致病机制中有重要作用，随着病程的发展，巨噬细胞根据微环境的变化转化为经典活化的M1型或选择性活化的M2型。在AMD进程中，M1／M2失衡可能是造成黄斑变性的原因之一。本文就AMD研究中的巨噬细胞极化现象进行总结，分别探讨巨噬细胞极化与干性AMD、湿性AMD及AMD相关的危险因素之间的关系。

关键词：年龄相关性黄斑变性巨噬细胞极化 M1型巨噬细胞 M2型巨噬细胞

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局部近场声全息的研究进展

农业机械学报 2008年第1期39卷 180-186页

作者：杨超陈进薛玮飞李加庆上海交通大学机械系统与振动国家重点实验室

局部近场声全息技术在解决实际工程问题时有优势,适于重建局部声场的各种声学量。阐述了局部近场声全息的技术原理及各种实现算法,并根据所提算法的创新性和受关注程度,把局部近场声全息技术归纳为4类:基于快速傅里叶变换的局部近场声... 详细信息

局部近场声全息技术在解决实际工程问题时有优势,适于重建局部声场的各种声学量。阐述了局部近场声全息的技术原理及各种实现算法,并根据所提算法的创新性和受关注程度,把局部近场声全息技术归纳为4类:基于快速傅里叶变换的局部近场声全息技术;基于等效源的局部近场声全息技术;基于统计最优的局部近场声全息技术;基于边界元的局部近场声全息技术。分析了各种方法的原理、发展过程以及研究现状。最后,提出了局部近场声全息技术研究的发展方向。

关键词：局部近场声全息研究进展综述