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图书情报知识 2005年第2期22卷 104-107页

作者：李东旻武汉大学信息管理学院武汉430072

利用网站信息自动评价方法,能够客观地按照网站运行的测量数据进行评价。本文分析了目前网站信息自动评价的现状,指出了网站信息自动评价的不足,并提出了解决方法。

关键词：自动评价网站评价网站自动评价信息资源

HIV and syphilis infections among street-based female sex workers in China, 2010-2012

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Chinese Medical Journal 2014年第4期127卷 707-711页

作者： li dongmin Wang Lu lin Wen li Peilong Wang Lan Guo Wei Ge lin Ding Zhengwei Cui Yan Wang Ning Division of Epidemiology National Center for Acquired Immune Definciency Syndrome/Sexually Transmitted Disease Control and Prevention Chinese Center for Disease Control and Prevention Beijing 102206 China Santa Clara County Public Health Department California 95126USA

Background Female sex workers （FSW） were high-risk population for HIV and other sexually transmitted diseases （STD） earlier,and now are an important driver of the HIV/AIDS epidemic in *** surveillance for FSW was set up to monitor the trend of HIV prevalence and risk behavior-related HIV *** study collected the data on street-based FSW from HIV sentinel surveillance system to understand HIV and syphilis infections,risk behaviors,and intervention in China from 2010 to *** The study population was the street-based FSW who were recruited for the national HIV integrated biological and behavioral surveillance between 2010 and *** information,HIV-related risk behaviors,and HIV and syphilis testing results were described and trend analysis was *** Between 2010 and 2012,the number of street-based FSW surveyed was 3725,3425,and 3335,*** knowledge awareness rate significantly increased from 74.6% in 2010 to 76.8% in 2011 and 82.2% in 2012 （P 〈0.01）.More FSW consistently used condom in the last month （49.0% in 2010; 51.0% in 2011; and 59.0% in 2012） and in the last commercial sex （72.0% in 2010; 78.5% in 2011; and 80.0% in 2012） over *** proportions of individuals who received HIV testing in the last year were 31.2% （2010）,37.0% （2011）,and 36.9% （2012）（P-trend 〈0.01）.HIV prevalence rate changed from 1.5% in 2010 to 1.4% in 2011 and 2.3% in 2012 （P-trend=0.01）.Syphilis prevalence rate was 6.9%,7.2%,and 7.1% in the same *** top three provinces with the highest average HIV prevalence rates over the 3 years were Guangxi （5.9%）,Yunnan （4.2%）,and Sichuan （1.2%）.Conclusions Street-based FSW are at high risk of HIV and syphilis *** efforts need to target streetbased FSW who are of old age and minority,who use illicit drugs and have syphilis infection.

关键词： street-based female sex worker HIV syphilis prevalence risk behaviors

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网站综合评价指标初探

情报理论与实践 2005年第3期28卷 303-306页

作者：李东旻武汉大学信息管理学院湖北430072

本文从网站设计、网站技术和网站内容三个方面展开,将各种网站评测方法具体应用在评价标准上,建立了一套网站综合评价指标,并对指标细则进行分析,使网站信息评价程序化,优化现有网站信息结构,也为新的网站建设提供参考。

关键词：综合评价指标网站设计网站内容网站技术评价标准具体应用评测方法信息评价信息结构网站建设程序化细则

女性苯丙胺类毒品滥用及其艾滋病性病患病风险研究进展

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中华流行病学杂志 2015年第1期36卷 90-93页

作者：李峥李东民汪宁北京协和医学院公共卫生学院 100730 中国疾病预防控制中心性病艾滋病预防控制中心

新型毒品主要是相对于传统毒品海洛因、鸦片、大麻和可卡因等而言,指人工化学合成的精神类药品/毒品,可直接作用于人的中枢神经系统,使人兴奋或抑制,连续使用能使人产生依赖性的一类药品（毒品）[1].其中,苯丙胺类新型毒品主要有冰毒、... 详细信息

新型毒品主要是相对于传统毒品海洛因、鸦片、大麻和可卡因等而言,指人工化学合成的精神类药品/毒品,可直接作用于人的中枢神经系统,使人兴奋或抑制,连续使用能使人产生依赖性的一类药品（毒品）[1].其中,苯丙胺类新型毒品主要有冰毒、摇头丸、麻谷等.此类毒品具有类似的母体化学结构,通过苯环上的不同取代基团而产生诸多衍生物,对机体产生中枢兴奋作用和致幻作用,主要包括苯丙胺、甲基苯丙胺、乙基安非他命、3,4-亚甲基二氧基甲基安非他明（MDMA）、3,4-亚甲基二氧基安非他明（替苯丙胺,MDA）等[2].其中甲基苯丙胺是冰毒和麻谷的主要毒性成分,MDMA是“摇头丸”的主要毒性成分[1].

关键词：苯丙胺类毒品女性药物滥用人类免疫缺陷病毒性病

Three-dimensional morphological and fluorescent imaging of zebrafish with a continuous-rotational light-sheet microscope

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Journal of Innovative Optical Health Sciences 2024年第2期17卷 59-66页

作者： dongmin Zhang Guang Yang Yao Tan Chong Chen Jie Zhang Hui li School of Biomedical Engineering(Suzhou)Division of life Sciences and Medicine University of Science and Technology of China Hefei 230041 P.R.China Suzhou Institute of Biomedical Engineering and Technology Chinese A cademy of Sciences Suzhou Jiangsu 215163P.R.China

light-sheet fluorescence microscopy(LSFM)has been widely used to image the three-dimensional(3D)structures and functions of various millimeter-size bio-specimen such as ***,the sample adsorption and scattering cause shading of the light-sheet illumination,preventing the even 3D image of thick ***,we report a continuous-rotational light-sheet microscope(CR-LSM)that enables simultaneous 3D bright-field and fluorescence *** a high-accuracy rotational stage,CR-LSM records the outline projections and the fluorescent images of the sample at multiple rotation ***,3D morphology and fluorescent structure were reconstructed with a developed *** CR-LSM,zebrafish’s whole-fish contour and blood vessel structures were obtained simultaneously.

关键词： light-sheet microscope zebrafish blood vessels morphology

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男男性行为人群扩大HIV检测策略研究进展

中华流行病学杂志 2023年第7期44卷 1163-1168页

作者：黄贵花李东民中国疾病预防控制中心性病艾滋病预防控制中心流行病学室北京102206

近年来,我国MSM的HIV感染率呈上升趋势。HIV检测是发现感染者的唯一途径,能够有效遏制HIV的传播和降低艾滋病相关死亡风险。目前我国MSM的HIV检测情况不容乐观,扩大HIV检测是该人群艾滋病防控工作的关键措施之一。本文对MSM扩大HIV检测... 详细信息

近年来,我国MSM的HIV感染率呈上升趋势。HIV检测是发现感染者的唯一途径,能够有效遏制HIV的传播和降低艾滋病相关死亡风险。目前我国MSM的HIV检测情况不容乐观,扩大HIV检测是该人群艾滋病防控工作的关键措施之一。本文对MSM扩大HIV检测的作用及策略进行综述,为开展该人群HIV检测相关工作提供参考。

关键词：男男性行为人群 HIV检测策略

我国男男性行为人群HIV自我检测及相关因素研究进展

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中华流行病学杂志 2023年第4期44卷 683-688页

作者：苏容李东民中国疾病预防控制中心性病艾滋病预防控制中心流行病学室北京102206

HIV检测是艾滋病防控工作的第一步,我国MSM的HIV感染率高,检测率低。HIV自我检测(HIV自检)为MSM提供了一个新的选择,对扩大HIV检测在该人群中的覆盖面具有重要作用。本文综述了我国MSM的HIV自检及相关因素,为HIV自检在该人群中的推广提... 详细信息

HIV检测是艾滋病防控工作的第一步,我国MSM的HIV感染率高,检测率低。HIV自我检测(HIV自检)为MSM提供了一个新的选择,对扩大HIV检测在该人群中的覆盖面具有重要作用。本文综述了我国MSM的HIV自检及相关因素,为HIV自检在该人群中的推广提供依据。

关键词：男男性行为人群艾滋病病毒自我检测

Identification of the differentially expressed genes related to HFD-MS through SSH

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Identification of the differentially expressed genes related...

Preliminary characterization of a novel metabolic syndrome associated RNA

中国生物化学与分子生物学会第十届会员代表大会暨全国学术会议

作者： Xi Lan dongmin li Bo Zhong Juan Ren Xuan Wang Yue li Shemin Lu Department of Genetics and Molecular Biology Xi’an Jiaotong University College of Medicine

The aim of this study was to select and identify the differentially expressed genes related to metabolic syndrome using a high-fat-diet-induced-metabolic-syndrome model (HFDMS) of E3 *** forward and reverse suppression subtractive hybridizations(SSH) were performed by using the total RNA extracted from HFD-MS livers of E3 rats and livers of control *** products of SSH were joined with pGEM-T Easy vector to establish the subtractive cDNA libraries,then the positive clones through JM109 transformation were ***,positive

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Preliminary characterization of a novel metabolic syndrome a...

Identification and preliminary characterization of a novel gene(MSAF1) associated with metabolic syndrome

生命的分子机器及其调控网络——2012年全国生物化学与分子生物学学术大会

作者： Xi Lan dongmin li Bo Zhong Juan Ren Xuan Wang Yue li Shemin Lu Department of Genetics and Molecular Biology Xi’an Jiaotong University School of Medicine

A novel gene associated with metabolic syndrome(MetS) in high-fat-diet-induced meta-bolic-syndrome(HFD-MetS) E3 rat models is ***:Several gene frag-ments,obtained by suppression subtractive hybridization,were cloned,sequenced,compared and confirmed.A novel gene associated with MetS was *** full-length cDNA of the novel gene was got by in silicon cloning and smart RACE *** bioinformatic methods were used to analyze and predict the feature and possible functions of the novel *** cellular expression of the novel gene was identified by *** that,the function of the novel

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Identification and preliminary characterization of a novel g...