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Optical and electrical anisotropy regulation engineering of low-dimensional materials toward polarized detection and imaging applications

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Rare Metals 2024年第7期43卷 2968-2993页

作者： Jian-Bin Zhang Nan Zhou li-Hui Zhang Cong-Hui Shang Jia-Xuan li Yi Zhao Guo-Hui Jia ru-Sen Yang Hua Xu Xiao-Bo li Shaanxi Joint Key Laboratory of Graphene Shaanxi Key Laboratory of High-Orbits-Electron Materials and Protection Technology for AerospaceShaanxi Joint Key Laboratory of GrapheneSchool of Advanced Materials and NanotechnologyXidian UniversityXi'an710126China Guangzhou Institute of Technology Xidian UniversityGuangzhou 710068China Xi'an Thermal Power Research Institute Co. LtdXi'an 710054China Key Laboratory of Applied Surface and Colloid Chemistry Ministry of EducationShaanxi Key Laboratory for Advanced Energy DevicesShaanxi Engineering Lab for Advanced Energy TechnologySchool of Materials Science and EngineeringShaanxi Normal UniversityXi'an Xi'an 710119China

Polarized-sensitive image sensors are a kind of photodetector with great development potential due to their enhanced ability to detect and identify the target objects from the aspect of spatial,spectral and polarized ***,low-dimensional anisotropic materials with inherent anisotropic properties,ultrathin thickness,tunable bandgap and feasible integration with complementary metal oxide semiconductor(CMOS)fabrication processes have attracted great interest for their facilitation of polarized photodetector devices *** the polarized detection performance of low-dimensional materials to satisfy realistic needs stimulates the exploration of modulation of anisotropic *** this review,we comprehensively introduce the latest research progress in modulating the optical and optoelectronic anisotropy characteristics of low-dimensional *** strategy of anisotropy regulation through crystal structure engineering and coupling system is discussed ***,the latest progress in image recognition applications using anisotropic low-dimensional materials is reviewed in ***,we summarize the challenge and propose future opportunities in the practical application of polarized-sensitive imaging photodetectors based on low-dimensional anisotropic materials.

关键词： Anisotropy Polarized detection Image recognition Low-dimensional materials

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Mitophagy in neurodegenerative disease pathogenesis

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Neural Regeneration Research 2024年第5期19卷 998-1005页

作者： Kan Yang Yuqing Yan Anni Yu ru Zhang Yuefang Zhang Zilong Qiu Zhengyi li Qianlong Zhang Shihao Wu Fei li Department of Developmental and Behavioural Pediatric&Child Primary Care Brain and Behavioural Research Unit of Shanghai Institute for Pediatric Research and MOE-Shanghai Key Laboratory for Children’s Environmental HealthXinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Center for Excellence in Brain Science and Intelligence Technology Institute of NeuroscienceState Key Laboratory of NeuroscienceCAS Key Laboratory of Primate NeurobiologyChinese Academy of SciencesShanghaiChina College of Materials and Chemical Engineering Hunan Institute of EngineeringXiangtanHunan ProvinceChina School of Medicine Yunnan UniversityKunmingYunnan ProvinceChina Songjiang Research Institute Shanghai Jiao Tong University School of MedicineShanghaiChina Neurosurgery Department Kunming Yenan HospitalKunmingYunnan ProvinceChina

Mitochondria are critical cellular energy resources and are central to the life of the *** selectively clears damaged or dysfunctional mitochondria through autophagic machinery to maintain mitochondrial quality control and *** neurons are postmitotic and consume substantial energy,thus require highly efficient mitophagy pathways to turn over damaged or dysfunctional *** evidence indicates that mitophagy is pivotal to the pathogenesis of neurological ***,more work is needed to study mitophagy pathway components as potential therapeutic *** this review,we briefly discuss the characteristics of nonselective autophagy and selective autophagy,including ERphagy,aggrephagy,and *** then introduce the mechanisms of Parkin-dependent and Parkin-independent mitophagy pathways under physiological ***,we summarize the diverse repertoire of mitochondrial membrane receptors and phospholipids that mediate ***,we review the critical role of mitophagy in the pathogenesis of neurodegenerative diseases including Alzheimer’s disease,Parkinson’s disease,and amyotrophic lateral ***,we discuss recent studies considering mitophagy as a potential therapeutic target for treating neurodegenerative ***,our review may provide novel views to better understand the roles of mitophagy in neurodegenerative disease pathogenesis.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis autophagy mitochondria mitophagy mitophagy receptor Parkin Parkinson’s disease PINK1

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Effect of Guanxin Danshen Dripping Pills on Coronary Heart Disease Comorbid with Depression or Anxiety: The ADECODE-Real World Study

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Chinese Journal of Integrative Medicine 2024年第5期30卷 443-448页

作者： WU Shi-hao SHI Wei-qi li Yu-hang liU ru-hui HU Da-yi ZHENG li-qiang MA Wen-lin Department of Geriatric Medicine Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Peking University People's HospitalBeijing 100044China School of Public Health Shanghai Jiao Tong UniversityShanghai 200030China

Objective: To evaluate the efficacy of Guanxin Danshen Dripping Pill(GXDSDP) in treating anxiety and depression in patients with coronary heart disease(CHD). Methods: A total of 1,428 patients diagnosed with CHD screened for anxiety, depression, and quality of life(QOL) at baseline received 0.4 g of GXDSDP treatment 3 times per day and returned for monthly reassessment. Patients were recruited after stable treatment for CHD and received assessment of General Anxiety Disorder-7(GAD-7), Patient Health Questionnaire-9(PHQ-9), and Seattle Angina Questionnaire(SAQ) for evaluating anxiety, depression, and *** were followed up 3 times, once every 4 weeks, during outpatient visits for 12 weeks. Results: At the third follow-up(F3), the anxiety symptom of 63.79%(673/1,055) of the patients improved to sub-clinical level, and the GAD-7 score improved significantly(8.11 vs. 3.87, Plinical level, with a significant improvement in PHQ-9 score(8.69 vs. 4.41, Pline(all Plimitation(31.17 vs. 34.14), anginal stability(2.74 vs. 4.14), anginal frequency(8.16vs. 9.10), treatment satisfaction(13.43 vs. 16.29), and disease perception(8.69 vs. 11.02). Conclusions: A fixed dosage of GXDSDP may be a potential treatment option for CHD patients comorbid with anxiety or depression.(Registration No. ChiCTR2100051523)

关键词： Guanxin Danshen Dripping Pill coronary heart disease depression anxiety quality of life Chinese medicine

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Single-pilot operations in commercial flight:Effects on neural activity and visual behaviour under abnormalities and emergencies

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Chinese Journal of Aeronautics 2024年第8期37卷 277-292页

作者： Qinbiao li chun-Hsien CHEN Kam K.H.NG Xin YUAN Cho Yin YIU Human Factors and Ergonomics Laboratory Department of Aeronautical and Aviation EngineeringThe Hong Kong Polytechnic UniversityHong Kong Special Administrative Region 100872China School of Mechanical&Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore

With cutting-edge technologies and considering airline human-resource-saving,a single pilot in commercial jets could be technically *** changes in captains’natural behaviours are initially required to comprehend the specific safe human performance envelope for safeguarding single-pilot flight,particularly in high-risk *** paper investigates how captains’performance transforms for fixing emergencies when operating from Dual-Pilot Operations(DPO)to Single-Pilot Operations(SPO)through a physiological-based *** pilots flew an emergency-included flight with/without first officers’*** neural activities and scanning behaviours were recorded using a 32-channel Electroencephalogram(EEG)and glasses-based eye tracker,with the observation and post-experiment questionnaires to evaluate the flight operations and pilots’*** alone,there was a significantly increased cortical activity in h and b waves over the frontal,parietal,and temporal lobes during the more complicated emergencies,and pilots focused less on the primary flight display while spending significantly more time scanning the other *** physiological fluctuating patterns associated with risky operations in SPO were highlighted by cross-correlating multimodal *** experimental-based noteworthy insights may wish to inform commercial SPO measures to lessen the persistent physiological fluctuation,assisting airlines in creating SPO-oriented intelligent flight systems to give captains adequate support for assuring safer air transportation.

关键词： Aviation engineering Single pilot operations Behaviour changes Eye tracker Electroencephalogram

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Intestinal glucagon-like peptide-1:A new player associated with impaired counterregulatory responses to hypoglycaemia in type 1 diabetic mice

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World Journal of Diabetes 2024年第8期15卷 1764-1777页

作者： Fang-Xin Jin Yan Wang Min-Ne li ru-Jiang li Jun-Tang Guo Department of Histology and Embryology Key Laboratory of Universities in Shandong ProvinceShandong Second Medical UniversityWeifang 261053Shandong ProvinceChina Department of Pathological Physiology Shandong Second Medical UniversityWeifang 261053Shandong ProvinceChina

BACKGROUND Impaired hypoglycaemic counterregulation has emerged as a critical concern for diabetic patients who may be hesitant to medically lower their blood glucose levels due to the fear of potential hypoglycaemic ***,the pathogenesis of hypoglycaemic counterregulation is still ***-like peptide-1(GLP-1)and its analogues have been used as adjunctive therapies for type 1 diabetes mellitus(T1DM).The role of GLP-1 in counterregulatory dysfunction during hypoglycaemia in patients with T1DM has not been *** To explore the impact of intestinal GLP-1 on impaired hypoglycaemic counterregulation in type 1 diabetic *** T1DM was induced in C57BL/6J mice using streptozotocin,followed by intraperitoneal insulin injections to create T1DM models with either a single episode of hypoglycaemia or recurrent episodes of hypoglycaemia(DH5).Immunofluorescence,Western blot,and enzyme-linked immunosorbent assay were employed to evaluate the influence of intestinal GLP-1 on the sympathetic-adrenal reflex and glucagon(GCG)*** GLP-1 receptor agonist GLP-1(7-36)or the antagonist exendin(9-39)were infused into the terminal ileum or injected intraperitoneally to further investigate the role of intestinal GLP-1 in hypoglycaemic counterregulation in the model *** The expression levels of intestinal GLP-1 and its receptor(GLP-1R)were significantly increased in DH5 *** instances of excess of intestinal GLP-1 weakens the sympathetic-adrenal reflex,leading to dysfunction of adrenal counterregulation during ***5 mice showed increased pancreaticδ-cell mass,cAMP levels inδcells,and plasma somatostatin concentrations,while cAMP levels in pancreaticαcells and plasma GCG levels ***,GLP-1R expression in islet cells and plasma active GLP-1 levels were significantly increased in the DH5 *** experiments involving terminal ileal infusion and intraperitoneal injection in the model mice demonstra

关键词： Glucagon-like peptide-1 Impaired hypoglycaemic counterregulation Type 1 diabetes Intestine Pancreas

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NODULATION TRIO in Medicago truncatula:Unveiling the redundant roles of MtLYK2,MtLYK3,and MtLYK2bis

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Journal of Integrative Plant Biology 2024年第8期66卷 1553-1556页

作者： Yaohua li Yanwen Zhao Ziang Yan ru Dong Haixiang Yu Hui Zhu Yangrong Cao National Key Lab of Agricultural Microbiology Hubei Hongshan LaboratoryHuazhong Agricultural UniversityWuhan 430070China

The legume–rhizobial symbiosis is a distinctive model in plant–microbe *** being foreign invaders,rhizobia are acknowledged as“friends”by compatible host plants,leading to mutualistic endosymbiosis(Cao et al.,2017).

关键词： mutual spite redundant

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高速公路沥青路面能耗与碳排放评价

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长安大学学报（自然科学版） 2016年第5期36卷 8-15页

作者：彭波蔡春丽胡如安长安大学公路学院陕西西安710064 郑州华路兴公路科技有限公司河南郑州450016 云南省交通科学研究院云南昆明650000

根据沥青路面建设实地调查,将沥青路面施工划分为集料堆料、集料干燥、沥青加热、沥青混合料拌和、运输、摊铺和压实7个环节;通过高速公路沥青路面施工碳源调查,得到了施工各环节能源消耗清单;基于能源消耗清单,采用热值法提出了高速公... 详细信息

根据沥青路面建设实地调查,将沥青路面施工划分为集料堆料、集料干燥、沥青加热、沥青混合料拌和、运输、摊铺和压实7个环节;通过高速公路沥青路面施工碳源调查,得到了施工各环节能源消耗清单;基于能源消耗清单,采用热值法提出了高速公路沥青路面碳排放量计算方法;根据高速公路沥青混合料能耗与碳排放现状调查,结合碳排放量计算方法,运用最大离差法计算了高速公路沥青路面建设各环节权重系数,提出碳排放关键环节,并建立了碳排放量评价模型,对碳排放进行分级评价;根据碳排放评价现状提出了以改变能源结构、改进加热方式、加强施工管理为主的低碳技术,以降低高速公路沥青路面建设中的碳排放量。研究结果表明:集料干燥、沥青加热环节的权重系数分别为0.517和0.320,占总权重的0.8以上,定义为沥青路面施工碳排放关键环节;根据所提出的碳排放评价指标EGI,将碳排放评价划分为优、良、一般、差4个等级;在关键环节低碳技术研究中,沥青加热环节将煤改换成天然气能够减少碳排放44.68%,集料干燥中将重油改换成天然气能够降低26.89%碳排放,减排效果显著。沥青路面施工碳排放评价分级和低碳技术研究为中国高速公路建设碳排放等级评定及可持续发展提供了技术可行、经济合理的减排措施。

关键词：道路工程高速公路沥青路面碳排放最大离差法权重系数碳排放分级

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A Comprehensive Overview of CFN From a Commonsense Perspective

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Machine Intelligence Research 2024年第2期21卷 239-256页

作者： ru li Yunxiao Zhao Zhiqiang Wang Xuefeng Su Shaoru Guo Yong Guan Xiaoqi Han Hongyan Zhao Key Laboratory of Computational Intelligence and Chinese Information Processing of Ministry of Education School of Computer and Information TechnologyShanxi UniversityTaiyuan 030006China

Chinese FrameNet(CFN)is a scenario commonsense knowledge base(CKB)that plays an important role in research on Chinese language *** is based on the theory of frame semantics and English FrameNet(FN).The CFN knowledge base contains a wealth of scenario commonsense knowledge,including frames,frame elements,and frame relations,as well as annotated instances with rich scenario-related labels on Chinese sentences and *** this paper,we conduct a comprehensive overview of CFN from a commonsense perspective,covering topics such as scenario commonsense representation,CFN resources,and its *** also summarize recent breakthroughs and identify future research ***,we introduce the concept of scenario commonsense,including its definitions,examples,and representation methods,with a focus on the relationship between scenario commonsense and the frame concept in *** addition,we provide a comprehensive overview of CFN resources and their applications,highlighting the newly proposed frame-based discourse representation and a human-machine collaboration framework for expanding the CFN ***,we explore emerging topics such as expanding the CFN resource,improving the interpretability of machine reading comprehension,and using scenario CKBs for text generation.

关键词： Chinese FrameNet(CFN) commonsense scenario commonsense frame knowledge

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Evaluation of the injection and plugging ability of a novel epoxy resin in cement cracks

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Petroleum Science 2024年第2期21卷 1211-1220页

作者： Guang-Yao Leng Wei Yan Hai-Mu Ye Er-Dong Yao Ji-Bin Duan Zheng-Xian Xu Ke-Pei li Jing-ru Zhang Zhong li State Key Laboratory of Petroleum Resource&Prospecting China University of Petroleum(Beijing)Beijing102249China CNPC liaohe Oilfield Gas Storage Co.LTD Panjin124000LiaoningChina CNOOC Research Institute Co. Ltd.Beijing100028China

Sustained casing pressure(SCP)is a crucial issue in the oil and gas production *** resins,exhibiting exceptional compressive strength,ductility,and shear bonding strength,have the potential to form reliable *** injectivity and sealing capacity of the epoxy resin is crucial parameters for the success of shallow remediation *** study aimed to develop and assess a novel solid-free resin sealant as an alternative to Portland cement for mitigating fluid *** investigation evaluated the viscosity,compressive strength,and brittleness index of the epoxy resin sealant,as well as its tangential and normal shear strengths in conjunction with casing *** flow characteristics and sealing abilities of conventional cement and epoxy resin were comparatively analyzed in *** results showed that the application of a viscosity reducer facilitated control over the curing time of the epoxy resin,ranging from 1.5 to 6 h,and reduced the initial viscosity from 865.53 to 118.71 m Pa,*** mechanical properties of the epoxy resin initially increased with a rise in curing agent content before experiencing a minor *** epoxy resin containing 30%curing agent exhibited optimal mechanical *** a 14-day curing period,the epoxy resin's compressive strength reached81.37 MPa,2.12 times higher than that of cement,whereas the elastic modulus of cement was 2.99 times greater than that of the epoxy *** brittleness index of epoxy resin is only 3.42,demonstrating high flexibility and *** tangential and normal shear strengths of the epoxy resin exceeded those of cement by 3.17 and 2.82 times,*** a 0.5 mm-wide crack,the injection pressure of the epoxy resin remained below 0.075 MPa,indicating superior injection and flow ***,the injection pressure of cement surged dramatically to 2.61 MPa within 5 *** breakthrough pressure of0.5 PV epoxy resin reached 7.53 MPa,decreasing the crack's perme

关键词： Sustained casing pressure Epoxy resin sealant Curing agent Viscosity reducer Mechanical properties Crack sealing

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Mechanism of local solidification time variations with melt rate during vacuum arc remelting process of 8Cr4Mo4V high-strength steel

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Journal of Iron and Steel Research International 2024年第2期31卷 377-388页

作者： Tao Pan Hong-chun Zhu Zhou-hua Jiang Hua-bing li rui Zhang Hao Feng School of Metallurgy Northeastern UniversityShenyang110819LiaoningChina State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang110819LiaoningChina

A 2D axisymmetric numerical model was established to investigate the variations of molten pool with different melt rates during the vacuum arc remelting of 8Cr4Mo4V high-strength steel,and the ingot growth was simulated by dynamic mesh *** results show that as the ingot grows,the molten pool profile changes from shallow and flat to V-shaped,and both the molten pool depth and the mushy width ***,the variation of both the molten pool shape and the mushy width melt rate is clarified by the thermal equilibrium *** melt rate increases,both the molten pool depth and the mushy width *** is caused by the increment in sensible heat stored in the ingot due to the limitation of the cooling capacity of the *** nonlinear increment in sensible heat leads to a nonlinear increase in the mushy *** addition,as melt rate increases,the local solidification time(LST)of ingot decreases obviously at first and then *** melt rate is controlled in a suitable range,LST is the lowest and the secondary dendrite arm spacing of the ingot is the smallest,which can effectively improve the compactness degree of 8Cr4Mo4V high-strength steel.

关键词： 8Cr4Mo4V high-strength steel Vacuum arc remelting process Melt rate Molten pool Local solidification time

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