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Sports Medicine and Health Science 2023年第4期5卷 269-276页

作者： Jianda Kong zhilin li Lei Zhu lin li Si Chen Qufu Normal University China

Age-related sarcopenia places a tremendous burden on healthcare providers and patients'*** flow restriction(BFR)training may be a promising treatment to bring sarcopenia down,and it offers numerous advantages over traditional resistance *** purpose of this review was to compare the effects of BFR training and conventional resistance training on clinically delayed sarcopenia in the *** such as PubMed,Web of Science,Embase,and Science Direct were searched to identify eligible studies;blinded data extraction was performed to assess study quality,and conflicts were submitted to third *** made the *** author used Review Manager(RevMan)5.4 and compared it with data obtained by another author for this purpose.A total of 14 studies met the inclusion criteria for this *** funnel plots of the studies did not show any substantial publication ***-load blood flow restriction(LL-BFR)had no significant effect on muscle mass compared with high-load resistance training(HL-RT)(p=0.74,SMD=0.07,95%CI:0.33 to 0.46)and LL-BFR had a significant effect on muscle strength compared with HL-RT(p=0.03,Z=2.16,SMD=-0.34,95%CI:0.65 to-0.03).LL-BFR showed a slight effect on mass compared to LL-RT(p=0.26,SMD=0.25,95%CI:0.19 to 0.69).Sensitivity analysis produced a nonsignificant change,suggesting that the results of this study are *** conclusion,the data suggest the possibility that BFR training improves age-related sarcopenia.

关键词： Blood flow restriction LL-BFR Resistance training Sarcopenia Older adults Systematic review Meta-analysis

Premonitory phenomenon of El Nino event reflected in the observations of LOD and sea level

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Chinese Science Bulletin 2000年第24期45卷 2231-2236页

作者： ZHENG Dawei DING Xiaoli ZHOU Yonghong CHEN Yongqi li zhilin liAO Xinhao Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Center of National Astronomical Observation Chinese Academy of SciencesBeijing 100012China Department of Land Surveying and Geo-Informatics Hong Kong Polytechnic UniversityHung HornKowloonHong KongChina

Data sets of the changes of the length of day, the sea surface temperature in the eastern Pacific and of the sea level in Hong Long from tide gauge observations are used to analyze and reveal the reflections in the observations of the length of day and the sea level changes concerned with the premonitory phenomenon of next El Nino event. The results from this study indicate that a new El Nino event has been brewing with the ending of the strong La Nina event that started in early summer of 1998. The estimated formation period of the new El Nino event will begin before the end of 2000, and the peak period may be reached at around the end of 2001.

关键词： change of the length of day sea level change El Nino event.

A tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody

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Bioactive Materials 2023年第3期21卷 299-312页

作者： zhilin li Hao Cai Zhiqian li Long Ren Xuelei Ma Hongyan Zhu Qiyong Gong Hu Zhang Zhongwei Gu Kui Luo Laboratory of Stem Cell Biology Department of RadiologyHuaxi MR Research Centner(HMRRC)Department of BiotherapyCancer CenterNational Clinical Research Center for GeriatricsFrontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu610041China Amgen Bioprocessing Centre Keck Graduate InstituteClaremontCA91711USA Functional and Molecular Imaging Key Laboratory of Sichuan Province And Research Unit of PsychoradiologyChinese Academy of Medical SciencesChengdu610041China

To improve the response rate of immune checkpoint inhibitors such as anti-PD-L1 antibody in immunosup-pressive cancers like triple-negative breast cancer(TNBC),induction of immunogenic cell death(ICD)at tumor sites can increase the antigenicity and adjuvanticity to activate the immune microenvironment so that tumors become sensitive to the intervention of immune checkpoint ***,a self-amplified biomimetic nanosystem,mEHGZ,was constructed by encapsulation of epirubicin(EPI),glucose oxidase(Gox)and hemin in ZIF-8 nanoparticles and coating of the nanoparticles with calreticulin(CRT)over-expressed tumor cell *** acts as an ICD inducer,Gox and hemin medicate the cascade generation of reactive oxygen species(ROS)to strengthen the ICD effect,and CRT-rich membrane as“eat me”signal promote presentation of the released antigens by dendritic cells(DCs)to invoke the tumor-immunity *** biomimetic delivery system displays an amplified ICD effect via Gox oxidation,hydroxyl radical generation and glutathione(GSH)*** induced potent ICD effect promotes DCs maturation and cytotoxic T lymphocytes(CTLs)infiltration,reversing an immunosuppressive tumor microenvironment to an immunoresponsive *** with the nanosystem in combination with anti-PD-L1 antibody results in distinctive inhibition of tumor growth and lung metastasis,supporting that a potent ICD effect can significantly boost the therapeutic efficacy of the anti-PD-L1 *** self-amplified biomimetic nanoplatform offers a promising means of raising the response rate of immune checkpoint inhibitors.

关键词： Cell membrane Biomimetic nanosystem Immunogenic cell death Immunotherapy anti-PD-L1 antibody

Carbon black supported ultra-high loading silver nanoparticle catalyst for electro-oxidation and determination of hydrazine

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Science China Chemistry 2013年第7期56卷 911-916页

作者： TAN Chang XU XinHua WANG Feng li zhilin liU JingJun JI Jing State Key Laboratory of Chemical Resource Engineering Beijing Key Laboratory of Electrochemical Process and Technology for Materials Beijing University of Chemical Technology

Carbon black supported ultra-high loading silver nanoparticle catalyst (Ag/CB) was prepared by a modified ethylene glycol reduction method, using ethylene glycol as the reducing agent and sodium hydroxide as the pH adjusting agent. The X-ray diffraction, thermogravimetry and scanning electron microscopy characterizations showed that the Ag nanoparticles crystallized with a face-centered cubic structure and were densely stacked on the CB surface without aggregation, despite such a small average size (ca. 10 nm) and an ultra-high loading mass (392 wt.%). The electrochemical evaluation based on cyclic voltammetry, chronoamperometry and polarization tests revealed that the ultra-high loading Ag/CB catalyst possessed a superior electrocatalytic activity for the oxidation of hydrazine, via a diffusion-limited process and a 4-electron transfer pathway. Moreover, the chronoamperometry response on an electrode modified with this ultra-high loading Ag/CB catalyst exhibited a promising application for determination of hydrazine, due to a broad linear calibration ranging from 50 to 800 μM, a high sensitivity of 0.03795 A/ M and a low detection limit of 3.47 μM.

关键词： carbon black silver nanoparticle catalyst oxidation of hydrazine determination

INJECTION MOLDED TUNGSTEN HEAVY ALLOY

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中国有色金属学会会刊：英文版 1998年第4期8卷 45-50页

作者： li Yimin, Qu Xuanhui, li zhilin and Huang Baiyun State Key Laboratory for Powder Metallurgy, Central South University of Technology, Changsha 410083, P. R. China State Key Laboratory for Powder Metallurgy Central South University of Technology Changsha 410083 China

ＩＮＴＲＯＤＵＣＴＩＯＮＭｅｔａｌＩｎｊｅｃｔｉｏｎＭｏｌｄｉｎｇ（ＭＩＭ），ｗｈｉｃｈｉｓｄｅｒｉｖｅｄｆｒｏｍｐｌａｓｔｉｃｉｎｊｅｃｔｉｏｎｍｏｌｄｉｎｇ，ｉｓａｋｉｎｄｏｆｎｅｗｌｙｄｅｖｅｌｏｐｅｄｐｏｗｄ... 详细信息

ＩＮＴＲＯＤＵＣＴＩＯＮＭｅｔａｌＩｎｊｅｃｔｉｏｎＭｏｌｄｉｎｇ（ＭＩＭ），ｗｈｉｃｈｉｓｄｅｒｉｖｅｄｆｒｏｍｐｌａｓｔｉｃｉｎｊｅｃｔｉｏｎｍｏｌｄｉｎｇ，ｉｓａｋｉｎｄｏｆｎｅｗｌｙｄｅｖｅｌｏｐｅｄｐｏｗｄｅｒｍｅｔａｌｕｒｇｙｆｏｒｍｉｎ...

关键词： injection molding heavy alloy powder loading

Calculation of the covalent electron density of (001) crystal plane of Fe_3C

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Chinese Science Bulletin 1997年第1期42卷 80-82页

作者： SUN Zhenguo, li zhilin and liU zhilinDepartment of Material Engineering, liaoning Institute of Technology, Jinzhou 121001, China Department of Material Engineering Liaoning Institute of Technology Jinzhou China

THE calculation method of the average covalent electron density （CED） of crystal planes with relatively dense atom arrangement in austenite and martinsite in Fe-C alloy has been advanced in refs. [1, 2]. The electron density of the biphase interface between （111） of austenite and （110） of martensite has also been discussed with that method. In this note, taking another important phase in Fe-C alloy, cementite （Fe3C） as research object, we advance a

关键词： Yu’s theory Cheng’s theory cementite interface electron theory.

The Four Intersection-and-Difference Model for line-line Topological Relations

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Geo-Spatial Information Science 2007年第4期10卷 293-298页

作者： DENG Min li zhilin li Guangqiang ZHANG Xuesong Department of Surveying and Geo-informatics Central South University Yuelu Mountain Changsha 410083. China

The description of line-line topological relations is still an unsolved issue although much effort has been done. The problem is involved in many practical applications such as spatial query, spatial analysis and cartographic generalization. To develop a sound and effective approach to describe line-line relations, it is first necessary to define the topology of an individual line, i.e., local topology. The concept of connective degree is used for the identification of topological differences in the geometric structure of a line. The general topological definition of a line is given, i.e., endpoints set and interior point set. This definition can be applied to the embedded spaces of different dimensions, whether co-dimension is equal to or larger than zero. On this basis, a generic model called the 4 intersection-and-difference is set up for the description of basic line-line topological relations, upon which a conceptual neighborhood graph is built with consideration of topological distance, it is concluded that the proposed model can represent the property of topological changes, and basic relations between line segments in IR^1 and IR^2.

关键词： topological relations line object topological distance conceptual neighborhood co-dimension

Picotesla-sensitivity microcavity optomechanical magnetometry

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light(Science & Applications) 2024年第11期13卷 2835-2846页

作者： Zhi-Gang Hu Yi-Meng Gao Jian-Fei liu Hao Yang Min Wang Yuechen Lei Xin Zhou Jincheng li Xuening Cao Jinjing liang Chao-Qun Hu zhilin li Yong-Chang Lau Jian-Wang Cai Bei-Bei li Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China School of Physics Beihang UniversityBeijing 100191China Songshan Lake Materials Laboratory Dongguan 523808 GuangdongChina

Cavity optomechanical systems have enabled precision sensing of magnetic fields,by leveraging the optical resonance-enhanced readout and mechanical resonance-enhanced *** studies have successfully achieved mass-produced and reproducible microcavity optomechanical magnetometry(MCOM)by incorporating Terfenol-D thin films into high-quality(Q)factor whispering gallery mode(WGM)***,the sensitivity was limited to 585 pT Hz^(−1/2),over 20 times inferior to those using Terfenol-D *** this work,we propose and demonstrate a high-sensitivity and mass-produced MCOM approach by sputtering a FeGaB thin film onto a high-Q SiO2 WGM *** studies are conducted to explore the magnetic actuation constant and noise-limited sensitivity by varying the parameters of the FeGaB film and SiO2 *** magnetometers with different radii are fabricated and *** utilizing a microdisk with a radius of 355μm and a thickness of 1μm,along with a FeGaB film with a radius of 330μm and a thickness of 1.3μm,we have achieved a remarkable peak sensitivity of 1.68 pT Hz^(−1/2)at 9.52 *** represents a significant improvement of over two orders of magnitude compared with previous studies employing sputtered Terfenol-D ***,the magnetometer operates without a bias magnetic field,thanks to the remarkable soft magnetic properties of the FeGaB ***,as a proof of concept,we have demonstrated the real-time measurement of a pulsed magnetic field simulating the corona current in a high-voltage transmission line using our developed *** high-sensitivity magnetometers hold great potential for various applications,such as magnetic induction tomography and corona current monitoring.

关键词： particles. magnetometer film

Fabrication and characterization of graphene derived from SiC

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Science China(Physics,Mechanics & Astronomy) 2013年第12期56卷 2386-2394页

作者： JIA YuPing GUO liWei LU Wei GUO Yu liN JingJing ZHU KaiXing CHEN lianlian HUANG QingSong HUANG Jiao li zhilin CHEN XiaoLong Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of Sciences

Using novel ideas for the fabrication of epitaxial graphene （EG） on SiC, two forms of graphene termed as vertical aligned gra- phene sheets （VAGS） and graphene covered SiC powder （GCSP） were derived, respectively, from SiC slices and SiC powder, aimed for applications in energy storage and photocatalysis. Herein, the fabrication procedures, morphology characteristics, some intrinsic physical properties and performances for applications in field effect transistor （FET） and cold cathode field emission source are revealed and analyzed based on the graphene materials. The EG on a 2-inch SiC （0001） showed an average sheet resistance about 720 D,/~5 with a non-uniformity 7.2%. The FETs fabricated on the EG possessed a cutoff frequency 80 GHz. Based on the VAGS derived from a completely carbonized SiC slice, a magnetic phase diagram of graphene with irregu- lar zigzag edges is also reported.

关键词： graphene SiC morphology Raman field emission magnetism

On the Onsager-Casimir reciprocal relations in a tilted Weyl semimetal

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Chinese Physics B 2022年第9期31卷 123-127页

作者： Bingyan Jiang Jiaji Zhao Lujunyu Wang Ran Bi Juewen Fan zhilin li Xiaosong Wu State Key Laboratory for Artificial Microstructure and Mesoscopic Physics Frontiers Science Center for Nano-optoelectronicsPeking UniversityBeijing 100871China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China Collaborative Innovation Center of Quantum Matter Beijing 100871China

The Onsager-Casimir reciprocal relations are a fundamental symmetry of nonequilibrium statistical *** we study an unusual chirality-dependent Hall effect in a tilted Weyl semimetal Co_(3)Sn_(2)S_(2) with broken time-reversal *** is confirmed that the reciprocal relations are *** two Berry curvature effects,an anomalous velocity and a chiral chemical potential,contribute to the observed Hall effect,the reciprocal relations suggest their intriguing connection.

关键词： Onsager-Casimir relations tilted Weyl semimetal chirality-dependent Hall effect