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CMGene：A literature-based database and knowledge resource for cancer metastasis genes

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Journal of Genetics and Genomics 2017年第5期44卷 277-279页

作者： Yining liu zhe li Jiachun Lu Min Zhao Hong Qu The School of Public Health Institute for Chemical CarcinogenesisGuangzhou Medical UniversityGuangzhou 510182 China Center for Bioinformatics State Key Laboratory of Protein and PlantGene ResearchCollege of Life SciencesPeking UniversityBeijing 100871 China The School of Public Health The First Affiliated HospitalGuangzhou Medical UniversityGuangzhou 510120 China School of Engineering Faculty of ScienceHealthEducation and EngineeringUniversity of the Sunshine CoastMaroochydore DCQueensland 4558 Australia Center for Bioinformatics State Key Laboratory of Protein and Plant Gene ResearchCollege of Life SciencesPeking UniversityBeijing 100871 China

Cancer metastasis is the end product of cancer evolution,contributing to the massive mortality of cancer patients（Chaffer and Weinberg,2011）.Different primary cancers have distinct spreading routes via the blood or ... 详细信息

关键词： metastasis metastatic abstracts contributing spreading mortality challenge sentences searching Weinberg

Single-atom Pd catalysts as oxidase mimics with maximum atom utilization for colorimetric analysis

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Nano Research 2022年第5期15卷 4411-4420页

作者： zhe li Fangning liu Yuanyuan Jiang Pengjuan Ni Chenghui Zhang Bo Wang Chuanxia Chen Yizhong Lu School of Materials Science and Engineering University of JinanJinan 250022China

Pd-based nanomaterials have shown great promise as potential mimic enzymes,but conventional catalysts use only a small fraction of the Pd content that located on the catalyst's ***,we demonstrated that maximum atom utilization could be achieved by using single-atom Pd catalysts as oxidase *** single-atom Pd nanozymes exhibit significantly enhanced catalytic efficiency,with a catalytic rate constant(Kcat)and the catalytic efficiency(Kcat/Km)values more than 625 and 4,837 times higher than those of horseradish peroxidase,respectively.A combined experimental and theoretical calculation reveals reactive oxygen species involved catalytic mechanism which endows single-atom Pd catalysts with excellent colorimetric analysis *** from the maximum atom utilization efficiency and well-defined structural features,the single-atom Pd nanozymes could be successfully applied for the total antioxidant capacity of fruit,determining the serum acid phosphatase activity as well as constructing NAND logic *** finding not only provides an effective strategy to maximize the noble-metal atom utilization efficiency as enzyme mimics,but also provides a new idea for extending their possible applications.

关键词： single-atom Pd catalysts oxidase mimics maximum atom utilization colorimetric analysis nanozymes

Oxidation of Silicon and Boron in Boron Containing Molten Iron

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Journal of Iron and Steel Research International 2007年第6期14卷 32-36页

作者： YANG Zhong-dong liU Su-lan li zhe-fu XUE Xiang-xin School of Materials and Metallurgy Northeastern University Shenyang 110004 Liaoning China

A new process of directly smelting boron steel from boron-containing pig iron has been established. The starting material boron-containing pig iron was obtained from ludwigite ore, which is very abundant in the eastern area of liaoning Province of China. The experiment was performed in a medium frequency induction furnace, and Fe2O3 powder was used as the oxidizing agent. The effects of temperature, addition of Fe2O3, basicity, stirring, and composition of melt on the oxidation of silicon and boron were investigated respectively. The results showed that sili- con and boron were oxidized simultaneously and their oxidation ratio exceeded 90% at 1 400℃. The favorable oxidation temperature of silicon was about 1 300-- 1 350℃. High oxygen potential of slag and strong stirring enhanced the oxidation of silicon and boron.

关键词： boron-containing pig iron oxidation silicon boron

Optimization of gearshift MAP based on DP for vehicles with automated transmission

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Science China(Information Sciences) 2018年第11期61卷 247-249页

作者： Xiaohui LU zhe li Lulu GUO Bingzhao GAO Niaona ZHANG Chuanxue SONG School of Mechatronic Engineering Changchun University of Technology State Key Laboratory of Automotive Simulation and Control Jilin University

Dear editor,The gearshift system is the key part of an automatic transmission vehicle that optimizes power and economy. An accurate and reasonable shift schedule has a significant theoretical and practical meaning for improving both dynamic and economic performances because it defines the control parameters used for the gearshift decision making and shift timing [1–3]. One gearshift strategy is to establish an optimal control problem to improve the overall performance. In the face of

关键词： DP Optimization of gearshift MAP based on DP for vehicles with automated transmission Figure AMESim

Stable Border Bases for Ideals of Numerical Cartesian Sets

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Communications in Mathematical Research 2011年第3期27卷 243-252页

作者： liU li-li li zhe ZHANG SHU-GONG Institute of Mathematics Jilin University Changchun 130012

In this paper, we discuss a special class of sets of bivariate empirical points, namely, numerical cartesian sets. We find that the stable quotient bases for numerical cartesian sets are unique if they exist. Furthermore, the corresponding border bases are the unique stable border bases for the vanishing ideals of numerical cartesian sets.

关键词： empirical point numerical cartesian set vanishing ideal border base

Hydrothermal Synthesis and Structural Characterization of Three-dimensional Metal-organic Framework [Zn_3(C_2H_2N_3)_2(C_7H_5O_2)_4]

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Chemical Research in Chinese Universities 2009年第1期25卷 1-4页

作者： SONG zhe li Guang-hua YU Yang SHI Zhan FENG Shou-hua College of Chemistry State Key Laboratory of Inorganic Synthesis and Preparative Chemistry Jilin University Changchun 130012 P. R. China

Hydrothermal reaction between mixed ligand（1,2,4-triazole and benzoic acid） and Zn（NO3）2·6H2O afforded a three-dimensional（3D） metal-organic framework Zn3（C2H2N3）2（C7H5O2）4（C2H2N3=1,2,4-triazole, C7H5O2=benzoic acid）. The compound was crystallized in the hexagonal system with space group R3： a=2.90234（9） nm, b=2.90234（9） nm, c=1.08597（5） nm, γ=120°, V=7.9222（5） nm^3, Mr=816.68, Dc=1.541 g/cm^3, Z=9, F（000）=3708, R=0.0636, and wR=0. 1777. Its structure consists of ZnN2O2 tetrahedron and ZnN204 octahedron, which are connected by 1,2,4-triazole and benzoic acid ligands to form a 3D framework with helical units. This compound forms an interpenetrated NbO topology. The compound was characterized by single-crystal X-ray diffraction, elemental analysis, FTIR spectra, and TGA measurements.

关键词： Hydrothermal synthesis Metal-organic framework 1,2,4-Triazole Benzoic acid Helical units

Impact of dietary fat levels and fatty acid composition on milk fat synthesis in sows at peak lactation

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Journal of Animal Science and Biotechnology 2023年第3期14卷 1134-1149页

作者： li zhe Uffe Krogh Charlotte Lauridsen Mette Olaf Nielsen zhengfeng Fang Peter Kappel Theil Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of EducationAnimal Nutrition InstituteSichuan Agricultural University211 Huimin RoadWenjiang DistrictChengdu 611130China Department of Animal and Veterinary Sciences Aarhus UniversityFoulumDk‑8830 TjeleDenmark

Background Dietary fat is important for energy provision and immune function of lactating sows and their ***,knowledge on the impact of fat on mammary transcription of lipogenic genes,de novo fat synthesis,and milk fatty acid(FA)output is sparse in *** study aimed to evaluate impacts of dietary fat levels and FA composition on these traits in *** second-parity sows(Danish Landrace×Yorkshire)were assigned to 1 of 5 dietary treatments from d 108 of gestation until weaning(d 28 of lactation):low-fat control diet(3%added animal fat);or 1 of 4 high-fat diets with 8%added fat:coconut oil(CO),fish oil(FO),sunflower oil(SO),or 4%octanoic acid plus 4%FO(OFO).Three approaches were taken to estimate de novo milk fat synthesis from glucose and body *** Daily intake of FA was lowest in low-fat sows within fat levels(Plized FA/d according to method *** low-fat diet increased mammary FAS expression(Plized body *** Sows fed diets with low-fat or octanoic acid,through upregulating FAS expression,increased mammary de novo fat synthesis whereas the milk FA output remained low in sows fed the low-fat diet or high-fat OFO or FO diets,indicating that dietary FA intake,dietary fat level,and body fat mobilization in concert determine de novo fat synthesis,amount and profiles of FA in milk.

关键词： Carbon metabolism De novo fat synthesis Dietary fatty acid Fat balance Mammary gene expression Mammary lipogenesis Milk fat production Piglet growth

Effects of Combined Treatment with Sansanmycin and Macrolides on Pseudomonas aeruginosa and Formation of Biofilm

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Biomedical and Environmental Sciences 2009年第2期22卷 170-177页

作者： YUE li YUN-YING XIE RU-XIAN CHEN HONG-ZHANG XU GUO-JI ZHANG JIN-zhe li AND XIAO-MIAN li Department of Microbiology Tianjin Medical University Tianjin 300070 China Department of Microbiology and Biochemical Pharmacy Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences Beijing 100050 China

Objective To observe the effects of combined treatment with sansanmycin and macrolides on Pseudomonas aeruginosa and formation of biofilm. Methods Micro-dilution method was used to determine the minimal inhibitory concentrations （MICs） of sansanmycin, gentamycin, carbenicillin, polymyxin B, roxithromycin, piperacillin, and tazobactam. PAl and PA27853 biofilms were observed under optical microscope after staining and under SEM after treatment with sansanmycin at different dosages and combined treatment with sansanmycin and roxithromycin. Viable bacteria in PAl and PA27853 biofilms were counted after treatment with sansanmycin at different dosages or combined treatment with sansanmycin and roxithromycin. Results The MIC of sansanmycin was lower than that of gentamycin and polymyxin B, but was higher than that of carbenicillin. Roxithromycin enhanced the penetration of sansanmycin to PAl and PA27853 strains through biofilms. PAl and PA27853 biofilms were gradually cleared with the increased dosages of sansanmycin or with the combined sansanmycin and roxithromycin. Conclusion Sub-MIC levels of roxithromycin and sansanmycin substantially inhibit the generation of biofilms and proliferation of bacteria. Therefore, combined antibiotics can be used in treatment of intractable bacterial infection.

关键词： Sansanmycin Macrolides Pseudomonas aeruginosa Biofilm

Study of the reinforced mechanism of fly ash on amphiphilic polymer gel

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Petroleum Science 2022年第5期19卷 2175-2184页

作者： Bo-Bo Zhou Wan-li Kang Hong-Bin Yang zhe li li-Ping Ma Shi-Tou Wang Jia-Qi Wang An-Qing Xie Bauyrzhan Sarsenbekuly Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao266580ShandongPR China School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongPR China Oil and Gas Technology Research Institute Changqing Oilfield Branch CompanyPetroChinaXi'an710018ShaanxiPR China Kazakh-British Technical University Almaty050000Kazakhstan

Amphiphilic polymer gels are widely used in heterogeneous reservoirs for conformance control ***,in high temperature and high salinity of calcium and magnesium reservoirs,amphiphilic polymer gels cannot maintain effective *** this work,a novel reinforced amphiphilic polymer gel(F-PADC gel)was prepared by physically mixing polymer solution and fly ash(FA),which is an extremely low cost *** viscoelasticity and stability of the F-PADC gel were studied by rheometry and *** reinforced mechanism of FA on amphiphilic polymer gels was *** results show that the addition of FA can make the gel more robust with a denser network *** the fifth day,the elastic modulus(G’)increases from 5.2 to 7.0 Pa and the viscosity modulus(G")increases from 0.4 to 0.6 Pa at the frequency of 1 Hz,which improves the viscoelasticity of the gel *** importantly,the F-PADC gel does not degrade after aging at 85℃for 180 *** its viscoelasticity increases obviously,G′and G"increase to 110.0 Pa and 3.5 Pa,respectively,showing excellent anti-aging ***,FA amphiphilic polymer gels have a good injectivity and a perfect plugging rate of 98.86%,which is better than that of sole amphiphilic polymer *** novel mixed FA amphiphilic polymer gels can prove to be a better alternative to conventional polymer gels to enhance oil recovery in high temperature and high salinity reservoirs.

关键词： Reinforced amphiphilic polymer gel Fly ash Anti-aging stability Conformance control