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K Variations and Anisotropy: Microstructure Effect and Numerical Predictions

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材料工程 2003年第Z1期31卷 307-320页

作者： li xu-dong( State Key Laboratory of Advanced Non-Ferrous Materials Gansu University of Technology Lanzhou Gansu 730050 China

Computer experiments were performed on simulated polycrystalline material samples that possess locally anisotropic microstructures to investigate stress intensity factor ( K ) variations and anisotropy along fronts of microcracks of different sizes. The anisotropic K , arising from inhomogeneous stresses in broken grains, was determined for planar microcracks by using a weight function-based numerical technique. It has been found that the grain-orientation-geometry-induced local anisotropy produces large variations in K along front of microcracks, when the crack size is of the order of few grain diameters. Synergetic effect of grain orientation and geometry of broken grains control K variations and evolution along the microcrack front. The K variations may diminish at large crack sizes, signifying a shift of K calculation to bulk stress dependence from local stress dependence. Local grain geometry and texture may lead to K anisotropy, producing unusually higher/lower K at a segment of the crack front. Either K variation or anisotropy cannot be ignored when assessing a microcrack.

关键词： K variation and anisotropy polycrystals microcracks grain orientation-geometry-induced anisotropy computer experiments numerical techniques

The　method　of　AF　synthetic　detection　on　crust　deformation　anomaly　and　its　applica-tion　in　earthquake

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Acta Seismologica Sinica(English Edition) 1998年第4期11卷 467-472页

作者： Niu, An-Fu li, xu-dong Wu, Jing Ke, li-Jun Institute of Seismology China Seismological Bureau Wuhan China

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关键词： AF anomaly detection Earthquake prediction Unstable model

Measuring Stress Distributions of Orthotropic Composite Material in Plane Stress State by the Lock-in Infrared Thermography Technique

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Chinese Physics Letters 2011年第6期28卷 179-182页

作者： li xu-dong WANG Wei-Bo li Yong-Sheng WU dong-liu China Aero-Polytechnology Establishment Beijing 100028 China Ship Scientific Research Center Wuxi 214082

Feasibility of measuring stress distributions of orthotropic composite materials and structures in plane stress state by the lock-in infrared thermography technique is analyzed and stress distributions of a lap joint structure made of a kind of glass reinforced plastic composite lamination plates under tensile loadings are obtained by the lock-in infrared thermography *** and credibility of using this technique to measure stress distributions of orthotropic composite materials and structures in plane stress state are proved by comparing the results with the data given by the digital speckle correlation method.

关键词： technique method orthotropic

A Novel Multi-sensor Data Fusion Algorithm and Its Application to Diagnostics

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仪器仪表学报 2005年第Z1期26卷 788-790页

作者： li Xiong xu Zongchang dong Zhiming Academy of Armored Force Engineering Beijing 100072China Academy of Armored Force Engineering Beijing 100072China Academy of Armored Force Engineering Beijing 100072China

To Meet the requirements of multi-sensor data fusion in diagnosis for complex equipment systems,a novel, fuzzy similarity-based data fusion algorithm is given. Based on fuzzy set theory, it calculates the fuzzy similarity among a certain sensor's measurement values and the multiple sensor's objective prediction values to determine the importance weigh of each sensor,and realizes the multi-sensor diagnosis parameter data *** to the principle, its application software is also designed. The applied example proves that the algorithm can give priority to the high-stability and high -reliability sensors and it is laconic ,feasible and efficient to real-time circumstance measure and data processing in engine diagnosis.

关键词： Diagnostics Multi-sensor Data fusion Algorithm Engine

Relationship between Carotid Atherosclerosis and Cerebral Infarction

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Chinese Medical Sciences Journal 2010年第1期25卷 32-37页

作者： Guang-wen li Guan-yi Zheng Jin-guo li xu-dong Sun Department of Geriatrics Union Hospital Fujian Medical University Fuzhou 350001 China

Objective To study the relationship between carotid atherosclerosis and cerebral infarction (CI). Methods Between November 2008 and March 2009,147 CI patients (CI group) and 48 patients with non-cerebrovascular diseases (control group) were enrolled from inpatients of Neurology Department of our hospital. The diagnostic criterion of thickened carotid intima was set as 1.0 mm≤intima-media thickness (IMT) 0.05). Conclusions Carotid atherosclerosis is to some extent able to reveal the atherosclerotic condition of cerebral arteries and act as an important predictor for the risk of CI. T

关键词： carotid atherosclerosis cerebral infarction intima-media thickness color Doppler ultrasonography

Lateral growth rate of δ phase during solidification of Fe-0.15wt%C-0.8wt%Mn steel

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International Journal of Minerals,Metallurgy and Materials 2012年第4期19卷 312-316页

作者： Guo-wei Chang Shu-ying Chen Qing-chun li xu-dong Yue Guang-can Jin School of Materials Science and Engineering Liaoning University of Technology Jinzhou 121001 China

Taking Fe-0.15wt%C-0.8wt%Mn steel as the research object, in situ observations of the 8 phase growth process during solidifica- tion were conducted by using a high-temperature confocal scanning laser microscope （HTCSLM）. The effects of the solid/liquid （S/L） inter- face＇s shape, temperature, and curvature radius on the lateral growth rate of 6 phase were investigated in detail, and the relational expression among the lateral growth rate of 5 phase, temperature, and curvature radius of column-shaped ~ phase was deduced for the carbon steel dur- ing solidificatiorL The results indicate the growth rate of the concave-shaped S/L interface is larger than that of the convex-shaped S/L inter- face during the beginning growth of ~ phase, but these two kinds of growth rates gradually approach with proceeding in solidification. The calculated lateral growth rate of 6 phase is consistent with the experimental result at a cooling rate of 0.045℃/s.

关键词： carbon steel solidification ferrite growth rate interfaces

Topological Aspects of Solitons in Ferromagnets

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Communications in Theoretical Physics 2008年第9期50卷 777-780页

作者： REN Ji-Rong WANG Ji-Biao li Ran xu dong-Hui DUAN Yi-Shi Institute of Theoretical Physics Lanzhou University Lanzhou 730000 China

Two kinds of topological soliton （skyrmion and magnetic vortex ring） in ferromagnets are studied. They have the common topological origin, a tensor Hαβ = n→·（δαn→×βδn→）, which describes the non-trivial distribution of local orientation of magnetization n→ at large distances in space. The topological stability of skyrmion is protected by the winding number. Knot-like topological defect as magnetic vortex rings is also studied. On the assumption that magnetic vortex rings are geometric lines, we present their δ-function distribution in ferromagnetic materials. Furthermore, it is briefly shown that Hopf invariant is a proper topological invariant to describe the topology of magnetic vortex rings.

关键词： ferromagnets skyrmions vortex rings

Fibrinogen-like protein 2/fibroleukin prothrombinase contributes to tumor hypercoagulability via IL-2 and IFN-γ

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World Journal of Gastroenterology 2008年第39期14卷 5980-5989页

作者： Kai Su Fang Chen Wei-Ming Yan Qi-li Zeng li xu dong Xi Bin Pi Xiao-Ping Luo Qin Ning Department of Infectious Diseases and Pediatrics Institute of Infectious Diseases Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology 1095 Jiefang Avenue Wuhan 430030 Hubei Province China

AIM： To examine the role of Fibrinogen-like protein 2 （fgl2）/fibroleukin in tumor development. Fgl2 has been reported to play a vital role in the pathogenesis in MHV-3 （mouse hepatitis virus） induced fulminant and severe hepatitis, spontaneous abortion, allo- and xenograft rejection by mediating ＂immune coagulation＂.METHODS： Tumor tissues from 133 patients with six types of distinct cancers and the animal tumor tissues from human hepatocellular carcinoma （HCC） model on nude mice （established from high metastasis HCC cell line MHCC97LM6） were obtained. RESULTS： HfgI2 was detected in tumor tissues from 127 out of 133 patients as well as tumor tissues collected from human HCC nude mice. Hfgl2 was highly expressed both in cancer cells and interstitial inflammatory cells including macrophages, NK cells, and CD8^＋ T lymphocytes and vascular endothelial cells. HfgI2 mRNA was localized in cells that expressed hfgI2 protein. Fibrin （nogen） colocalization with hfgl2 expression was determined by dual immunohistochemical staining. In vitro, IL-2 and IFN-γ, increased hfgl2 mRNA by 10-100 folds and protein expression in both THP-1 and HUVEC cell lines. One-stage clotting assays demonstrated that THP-1 and HUVEC cells expressing hfgl2 had increased procoagulant activity following cytokines stimulation. CONCLUSION： The hfgI2 contributes to the hypercoagulability in cancer and may induce tumor angiogenesis and metastasis via cytokine induction.

关键词： Fibrinogen-like protein 2/fibroleukin Thrombin Tumor Coagulation Cytokine

Effects of Toluene on the Development of the Inner Ear and Lateral line Sensory System of Zebrafish

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Biomedical and Environmental Sciences 2021年第2期34卷 110-118页

作者： li xu dong TU Hong Wei HU Ke Qi liU Yun Gang MAO li Na WANG Feng Yan QU Hong Ying CHEN Qing Department of Epidemiology School of Public HealthSouthern Medical UniversityGuangzhou 510515GuangdongChina Guangdong Province Hospital for Occupational Disease Prevention and Treatment Guangzhou 510300GuangdongChina Guangdong Provincial Center for Diseases Control and Prevention Guangzhou 511430GuangdongChina Department of Toxicology School of Public HealthSouthern Medical UniversityGuangzhou 510515GuangdongChina Guangdong Provincial Key Laboratory of Occupational Disease Prevention and Treatment Guangzhou 510300GuangdongChina

Objective The aim of this study was to explore the ototoxicity of toluene in the early development of zebrafish embryos/*** Zebrafish were utilized to explore the ototoxicity of toluene. Locomotion analysis,immunofluorescence, and q PCR were used to understand the phenotypes and molecular mechanisms of toluene *** The results demonstrated that at 2 mmol/L, toluene induced zebrafish larvae death at 120 hours post fertilization(hpf) at a rate of 25.79% and inhibited the rate of hatching at 72 ***, toluene exposure inhibited the distance travelled and average swimming velocity of zebrafish larvae while increasing the frequency of movements. As shown by fluorescence staining of hair cells, toluene inhibited the formation of lateral line neuromasts and middle line 1(Ml1) neuromasts in 3 days post fertilization larvae in a concentration-dependent manner. Toluene altered the expression level of genes involved in ear development/function in zebrafish, among which the m RNA levels of cd164 l2,tekt3, and pcsk5 a were upregulated, while the level of otofb was downregulated, according to the q PCR *** This study indicated that toluene may affect the development of both the inner ear and lateral line systems in zebrafish, while the lateral line system may be more sensitive to toluene than the inner ear.

关键词： Toluene Ototoxicity Zebrafish Lateral line sensory system