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Formulation of international standards of Chinese medicine technology:clinical practice guide of Chinese medicine for cough

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Journal of Traditional Chinese Medicine 2024年第2期44卷 396-402页

作者： FANG Hanyu HONG Zheng li Deming ZHANG Hongchun SHI Yihang li xiaojuan SUN Zengtao CHEN Wei ZHANG Chuchu ZU Yaqi Beijing University of Chinese medicine Beijing 100029China Department of Traditional Chinese Medicine for Pulmonary Diseases Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029 National Center for Respiratory Medicine Beijing 100029China Department of Traditional Chinese Medicine for Pulmonary Diseases Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China Tianjin University of Traditional Chinese Medicine Tianjin 301617China Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin 300250China Center for Evidence-based Medicine Beijing University of Chinese MedicineBeijing 100029China Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China

OBJECTIVE:To formulate the first clinical practice guideline for the treatment of cough using Chinese medicine based on the grading of recommendations assessment,development,and evaluation(GRADE)systematic approach,including clinical evidence,evaluation of ancient literature,and expert ***:In the process of development,the regulation of"evidence-based,consensus-assisted,and empirical"was followed,and a comprehensive systematic approach of recommendation assessment,GRADE,evidence-based evaluation,expert consensus,and the Delphi method was *** the process of guideline development,evidence-based evaluation of ancient literature was included for the first time,and clinical evidence was fully integrated with clinical expert ***:The clinical practice guidelines for the treatment of cough with Chinese herbal medicine were developed after a comprehensive consideration of evidence-based evaluation and expert *** guideline recommendations focused on recommending herbal compound decoctions and Chinese patent medicines for cough in different *** on the GRADE systematic approach,we conducted an evidence-based evaluation of the recommended Chinese patent medicines one by one;meanwhile,the expert consensus method was used to unify the recommendations of ***:Based on clinical evidence,ancient literature evaluation,and expert consensus,a clinical practice guideline for Traditional Chinese Medicine(TCM)in the treatment of cough was developed,providing the first current clinical practice guideline for domestic and foreign TCM and Western medicine practitioners,especially respiratory professionals at home and abroad.

关键词： Medicine Chinese Traditional clinical practice cough practice guide international standard

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Highly robust zinc metal anode directed by organic–inorganic synergistic interfaces for wearable aqueous zinc battery

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SmartMat 2024年第1期5卷 135-146页

作者： Xixi Zhang Chuanlin li Guangmeng Qu Chenggang Wang Shunshun Zhao Tongkai Wang Na li xiaojuan li Xijin Xu School of Physics and Technology University of JinanJinanChina School of Chemistry and Chemical Engineering Shandong UniversityJinanChina State Key Laboratory of Chemical Resource Engineering Beijing Key Laboratory of Electrochemical Process and Technology of MaterialsBeijing University of Chemical TechnologyBeijingChina

Flexible aqueous zinc batteries(FAZBs)with high safety and environmental friendliness are promising smart power sources for smart wearable ***,the bare zinc anode usually suffers from damnable dendrite growth and rampant side reaction on the surface,greatly impeding practical applications in ***,a composite polymer interface layer is artificially self‐assembled on the surface of the zinc anode by graft‐modified fluorinated monomer(polyacrylic acid‐2‐(Trifluoromethyl)propenoic acid,PAA‐TFPA),on which an organic–inorganic hybrid(PAA‐Zn/ZnF2)solid electrolyte interface(SEI)with excellent ionic conductivity is formed by interacting with Zn2+.Both the pouch cell and fiber zinc anode exhibit excellent plating/stripping reversibility after protecting by this organic–inorganic SEI,which can be stably cycled more than 3000 h in symmetric Zn||Zn cells or 550 h in fiber Zn||Zn ***,this interface layer preserves zinc anode with excellent mechanical durability under various mechanical deformation(stably working for another 1200 h after bending 100 h).The corresponding PAA‐Zn/ZnF2@Zn||MnO2 full cell displays an ultra‐long life span(79%capacity retention after 3000 cycles)and mechanical robustness(85%of the initial capacity for another 3000 cycles after bending 100 times).More importantly,the as‐assembled cells can easily power smart wearable devices to monitor the user's health condition.

关键词： hybrid SEI mechanical durability wearable zinc battery zinc anode

Single-cell characterization of major components of plant cell walls in situ by Raman spectroscopy

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Science China(life Sciences) 2024年第8期67卷 1772-1774页

作者： Yujian li Weiwei Shen Xi Zhang Yaning Cui Yuanyuan Zhao Yayu Guo xiaojuan li Shuizhong Wang Guoyong Song Pu Wang Jianfeng Ma Jinxing lin State Key Laboratory of Efficient Production of Forest Resources College of Biological Sciences and TechnologyBeijing Forestry UniversityBeijing 100083China Institute of Tree Development and Genome Editing Beijing Forestry UniversityBeijing 100083China National Engineering Research Center of Tree Breeding and Ecological Restoration College of Biological Sciences and TechnologyBeijing Forestry UniversityBeijing 100083China Beijing Key Laboratory of lignocellulosic Chemistry Engineering Research Center of Forestry Biomass Materials and EnergyMinistry of EducationBeijing Forestry UniversityBeijing 100083China Beijing Advanced Innovation Center for Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijing 100191China Key lab of Bamboo and Rattan Science&Technology International Center for Bamboo and RattanBeijing 100102China

Dear Editor,Plant cell walls are complex and dynamic structures that are mainly composed of polysaccharide polymers such as cellulose,hemicellulose,and pectin,in addition to substantial amounts of the non-saccharide polymer lignin(McFarlane et al.,2014;German et al.,2023).The components of cell walls are interconnected in various ways to form a complex,multilayered network structure(Wen et al.,2023).

关键词： walls cellulose characterization

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关于信息领域科技成果转化的一点思考

中国科学院院刊 2024年第2期39卷 367-372页

作者：孙凝晖李小娟中国科学院计算技术研究所北京100190

促进科技成果转化一直是我国科技创新政策关注的重点。但是,由于科技成果的特殊性、复杂性和专业性,使得科技成果转化难成为世界各国面临的共性问题。我国的科技成果转化工作同样存在许多值得商榷和探索的地方,尤其是对于科研院所是否... 详细信息

促进科技成果转化一直是我国科技创新政策关注的重点。但是,由于科技成果的特殊性、复杂性和专业性,使得科技成果转化难成为世界各国面临的共性问题。我国的科技成果转化工作同样存在许多值得商榷和探索的地方,尤其是对于科研院所是否能以创办企业的方式做成果转化,还存在争议。文章以信息技术领域为例,通过分析知识产权许可转让、产学研合作、创办企业等几种主要的成果转化形式的优缺点和适用场景,对这个问题发表一点看法。

关键词：科技成果转化知识产权许可转让产学研合作企业创办

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Rocking-chair ammonium ion battery with high rate and long-cycle life

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Chinese Chemical Letters 2024年第1期35卷 563-567页

作者： Tongkai Wang xiaojuan li Shunshun Zhao Hongxia Bu Chuanlin li Na li Xixi Zhang Xijin Xu School of Physics and Technology University of JinanJi'nan 250022China State Key Laboratory of Chemical Resource Engineering Beijing Key Laboratory of Electrochemical Process and Technology of MaterialsBeijing University of Chemical TechnologyBeijing 100029China College of Physics and Electronic Engineering Qilu Normal UniversityJi'nan 250200China

Aqueous rechargeable ammonium-ion batteries(AIBs)have drew considerable attention because of their capacity for high rates,low cost,and high ***,developing desired electrodes requiring stable structure in the aqueous fast ammoniation/de-ammoniation becomes ***,an ammonium ion full battery using Cu_(3)[Fe(CN)_(6)]_(2)(CuHCF)acting to be a cathode and barium vanadate(BVO)acting to be an anode is *** excellent electrochemical behavior of Prussian blue analogs and the perfectly matched lattice structure of NH_(4)^(+)is *** the open structure of vanadium compounds satisfies the fast ammoniation/de-ammoniation of NH4+is also *** a result of these synergistic effects,the BVO//CuHCF full cell retains 80.5 percent of its capacity following 1000 *** achievements provide new ideas for developing low-cost and long-life AIBs.

关键词： Copper hexacyanoferrate Vanadium-based compounds Aqueous ammonium ion batteries Long-term cyclability Ammonium ion storage mechanism

关于公共科研机构应对开源中知识产权问题的思考

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中国科学院院刊 2024年第8期39卷 1307-1312页

作者：包云岗李小娟中国科学院计算技术研究所

开源在创新迭代、生态拓展和国际化发展等方面可以起到积极作用，但科研院所、大学等公共科研机构，在将成果进行开源或者参与建设开源社区等活动时，面临着国有资产管理、知识产权处置、法律风险防控等方面的问题。文章从开源项目的捐... 详细信息

开源在创新迭代、生态拓展和国际化发展等方面可以起到积极作用，但科研院所、大学等公共科研机构，在将成果进行开源或者参与建设开源社区等活动时，面临着国有资产管理、知识产权处置、法律风险防控等方面的问题。文章从开源项目的捐赠、开源许可证的选择、开源专利池的构建等几个方面，为应对上述问题提供一些思考和建议。

关键词：开源知识产权公共科研机构

2020-2021年长治地区咽峡炎链球菌群感染临床特征及耐药性分析

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长治医学院学报 2024年第2期38卷 91-95页

作者：程亚平纪爱芳韩璐李小娟长治医学院山西长治046000 长治医学院附属和平医院检验科

目的:探讨2020-2021年长治地区咽峡炎链球菌群(SAG)感染的临床特征及耐药性。方法:收集189例SAG感染患者资料进行临床特征分析,使用WHONET5.6软件对SAG菌株类型及药敏结果进行统计,并对不同感染部位菌株药物耐药率作比较分析。结果:长... 详细信息

目的:探讨2020-2021年长治地区咽峡炎链球菌群(SAG)感染的临床特征及耐药性。方法:收集189例SAG感染患者资料进行临床特征分析,使用WHONET5.6软件对SAG菌株类型及药敏结果进行统计,并对不同感染部位菌株药物耐药率作比较分析。结果:长治地区SAG阳性病例中,男性(61.90%)多于女性(38.10%);平均年龄(51.0±14.5)岁;有脓肿形成的患者117例(61.90%),中间链球菌形成脓肿的概率最大;SAG所致感染类型以口腔感染(49例,25.93%)、腹腔感染(36例,19.05%)为主;SAG血流感染组患者合并基础疾病比例、存在免疫抑制比例、住院天数及炎性指标值(C反应蛋白、血清淀粉样蛋白A、降钙素原)高于非血流感染组患者(P<0.05);SAG对克林霉素、红霉素、四环素、左旋氧氟沙星耐药率分别为73.04%、65.14%、38.62%、9.00%,对其他种类抗生素未见耐药;口腔、腹腔、泌尿生殖系统3个感染部位SAG分离株对左旋氧氟沙星耐药率组间差异有统计学意义(P<0.05),泌尿生殖系统感染部位SAG分离株对左旋氧氟沙星耐药率较口腔、腹腔感染部位分离株耐药率明显升高(P<0.05)。结论:SAG感染患者若合并基础疾病、存在免疫抑制,且炎性指标值明显升高时,应注意患者是否发生SAG血流感染;SAG对大环内酯类及林可酰胺类药物耐药率较高。

关键词：咽峡炎链球菌群临床特征耐药率

统编普通高中思想政治教材的劳动精神内容分析

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天津师范大学学报（基础教育版） 2024年第1期25卷 7-12页

作者：李晓娟李萌西南大学教师教育学院重庆400715

运用内容分析法对统编普通高中思想政治教材中的劳动精神内容进行梳理和分析,研究发现,教材中劳动精神内容呈现以下样态:理论性突出但实践性尚显不足,正辅文配合呈现但编排稍显零散,隐性呈现较多而显性呈现较少,重视思维发展的层次性但... 详细信息

运用内容分析法对统编普通高中思想政治教材中的劳动精神内容进行梳理和分析,研究发现,教材中劳动精神内容呈现以下样态:理论性突出但实践性尚显不足,正辅文配合呈现但编排稍显零散,隐性呈现较多而显性呈现较少,重视思维发展的层次性但高阶思维培养取向或有不足。基于上述样态,研究认为,教师在教学中应采取以下策略:增强实践体验促进知行合一,有效利用教材内容组织大单元教学,加强教师对教材的分析和利用,依托学习活动和评价促进学生高阶思维发展。

关键词：劳动精神统编普通高中思想政治教材现实样态教学策略

双线阵推扫成像光学遥感卫星在轨动目标检测方法

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地球信息科学学报 2024年第4期26卷 1040-1056页

作者：杨灿坤李小娟李韦钟若飞李清扬杜鑫首都师范大学资源环境与旅游学院北京100028 首都师范大学三维信息获取与应用教育部重点实验室北京100028

动目标检测是从时序图像中获取时间维度动态变化信息的有效手段,通过快速获取、分析和利用卫星遥感数据中的现势信息,将遥感数据中时空域运动和变化信息表征为对象和知识,可以有效提升卫星数据的利用效率,实现“现势数据、即时传输”的... 详细信息

动目标检测是从时序图像中获取时间维度动态变化信息的有效手段,通过快速获取、分析和利用卫星遥感数据中的现势信息,将遥感数据中时空域运动和变化信息表征为对象和知识,可以有效提升卫星数据的利用效率,实现“现势数据、即时传输”的应用要求。现有的卫星视频和多光谱遥感图像用于动目标检测领域,无法满足大范围动目标发现、运动速度适应性以及硬件加速兼容性等应用需求。本文以利用光学遥感卫星实现大范围动目标快速感知为目标,通过双线阵推扫光学遥感相机采集包含时域动目标信息的双条带图像,以船舶目标为例,经过在轨处理形成动目标关键信息。相机原理样机已经搭载“泰景四号01星”于2022年2月27日成功发射,验证了大范围动目标检测的技术路线。本文在提出双线阵推扫成像方法以及动目标时空特性数学模型基础上,构建基于显著性区域建议的动目标检测方法,利用时空域变化信息表征和提取动目标显著性区域,基于深度学习目标检测技术实现动目标判别,获取动目标检测结果。利用在轨拍摄的双条带图像,验证了算法精度,对比传统算法,本文方法在单体目标分割方面提升明显,动目标分割结果较为完整、清晰,有效提升了动目标两个时刻间的匹配精度。结果表明,算法能够有效实现双条带图像中的动目标检测,具有以下2个方面的优势:(1)提出双条带推扫成像模式和方法,扩展图像时域信息,解决卫星无机动条件下大范围动目标观测问题;(2)提出基于显著性区域建议的动目标检测模型,解决了大范围双条带图像中复杂背景下动目标检测问题。通过获取动目标关键信息,大幅度减少遥感信息的对地传输带宽需求,可以为大规模对地观测系统数据在轨处理与地学应用提供新型的数据获取与处理思路。

关键词：双线阵推扫双条带影像动目标检测在轨智能处理时空域变化信息单体目标分割深度学习目标检测显著性区域建议

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