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A novel Tb^(3+) and Eu^(3+) co-doped dual-emitting phosphate K_(3)SrBi(P_(2)O_(7))_(2) phosphor for application in FIR thermometers

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Journal of Rare Earths 2024年第3期42卷 455-463,I0001页

作者： Baochen Wang Shifeng Sun Zeqi li Zongwang li Weiwei lin Chao Zeng Yan-gai liu ruiyu Mi School of Chemical and Environmental Engineering Anhui Polytechnic UniversityWuhu241000China State-Province Joint Engineering Laboratory of Zeolite Membrane Materials Key Lab of Fluorine and Silicon for Energy Materials and Chemistry of Ministry of EducationInstitute of Advanced MaterialsCollege of Chemistry and Chemical EngineeringJiangxi Normal UniversityNanchang330022China Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid Wastes National Laboratory of Mineral MaterialsSchool of Materials Science and TechnologyChina University of GeosciencesBeijing100083China

Rare earth co-doped phosphor for fluorescence intensity ratio(FIR) thermometer has gained increasing attention in recent years. Herein, the novel Tb^(3+)and Eu^(3+)co-doped K_(3)SrBi(P_(2)O_(7))_(2)(KSBP) phosphate phosphors were reported. The crystal structure of the title phosphor was determined using Rietveld refinement and proved to have a three-dimensional structure. The time-resolved spectroscopy reveals that there is almost no energy transfer between Tb^(3+)and Eu^(3+). More importantly, Tb^(3+)and Eu^(3+)emissions show different thermal quenching behaviors, which claims the potential of this material for application in optical thermometer. The FIR of the typical KSBP:0.02Tb^(3+),0.04Eu^(3+)sample demonstrates a polynomial relationship as a function of temperature and the absolute and relative sensitivity are0.025 K^(-1) and 0.59%/K, respectively. In general, our study reports a novel and potential KSBP:Tb^(3+),Eu^(3+)phosphate phosphor that is promising for use in high-sensitive FIR thermometers.

关键词： Phosphor Thermometer Fluorescence intensity ratio Thermal stability Rare earths

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EFFECTS OF JIANG TANG FANG LONG FORMULA ON INSUliN PRODUCTION AND FUNCTION IN AN ANIMAL MODEL OF DIABETIC HEARING LOSS

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Journal of Otology 2013年第2期8卷 88-90页

作者： YANG Yunxia li ruiyu JING Jianmei ZHANG Yanzhuo li Meng li Bin FENG Jinping li li li Huizhen Department of Laboratory Xingtai People’s Hospital Second Affiliated Hospital of Xingtai Medical College Medical Team of Hetian Detachment Xinjiang Armed Police Department of Biochemistry Hebei Medical University

Objective To study the influence of Jiang Tang Fang Long formula on insulin production and function in an animal model of diabetic hearing loss. Methods Wistar rats (n=60) were randomly divided into 6 groups (10 in each) to receive no treatment (the normal control, Group A), or to receive intra-peritoneal 55 mg/kg streptozotocin with (Groups C, D and E) or without (Group B) subsequent Jiang Tang Fang Long formula treatment at various doses or Yu Long Wan treatment (Group F). After 60 days, fasting blood glucose (FBG), body weight (BW) and fasting insulin (FINS) were recorded and the HOMA-IR and HOMA-βcalcu-lated. Insulin expression in pancreatic tissues was measured by radioimmunoassay. Results Compared with animals that received streptozotocin without rescue treatment (Group B), animals that received higher doses of Jiang Tang Fang Long formula(Groups D and E) showed improved indices of diabetes manifestation (Plin expression in pancreatic islets (P0.05). Conclusion Our results suggest that Jiang Tang Fang Long formula may improve pancreatic β-cells function which may explain its efficacy in treating diabetic hearing loss.

关键词： Jiang Tang Fang Long formula diabetes deafness Wistar rats streptozocin

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针刺治疗缺血性卒中后肢体功能障碍的神经影像研究概况

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中华针灸电子杂志 2024年第2期13卷 78-82页

作者：田春蕾李瑞雨肖凌勇刘艺王晓璇戴晓矞天津中医药大学第一附属医院针灸部 300381 国家中医针灸临床医学研究中心天津300381

针刺治疗缺血性卒中肢体功能障碍疗效肯定,但其中枢作用机制目前尚不明确。磁共振成像技术可提供软组织结构、功能、代谢等丰富的图像信息,为探索针刺治疗缺血性卒中肢体功能障碍的中枢机制提供了技术支持。通过检索近5年关于针刺治疗... 详细信息

针刺治疗缺血性卒中肢体功能障碍疗效肯定,但其中枢作用机制目前尚不明确。磁共振成像技术可提供软组织结构、功能、代谢等丰富的图像信息,为探索针刺治疗缺血性卒中肢体功能障碍的中枢机制提供了技术支持。通过检索近5年关于针刺治疗缺血性卒中后肢体功能障碍的神经影像学方面的文献,结果发现针刺主要通过调控运动功能区的自主神经活动、促进M1区的功能连接、重构脑组织结构等方式改善患者肢体运动功能。今后研究应尝试新型影像技术及数据分析方法,并严格控制针刺变量,多角度探索针刺治疗缺血性脑卒中肢体功能障碍的中枢机制。

关键词：缺血性卒中针刺四肢磁共振成像

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Mechanical Janus lattice with plug-switch orientation

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Theoretical & Applied Mechanics Letters 2024年第1期14卷 23-26页

作者： Yupei Zhang Jiawei Zhong Zhengcai Zhao ruiyu Bai Yanqi Yin Yang Yu Bo li State Key Laboratory for Manufacturing System EngineeringShaanxi Key Laboratory of Intelligent Robots School of Mechanical Engineering Xi’an Jiaotong UniversityXi’an 710049China Qian Xuesen Honors College Xi’an Jiaotong UniversityXi’an 710049China

In recent years,materials with asymmetric mechanical response properties(mechanical Janus materials)have been found possess numerous potential applications,*** absorption and vibration *** this study,we propose a novel mechanical Janus lattice whose asymmetric mechanical response can be switched in orientation by a *** finite element analysis and experimental verification,this lattice exhibits asymmetric displacement responses to symmetric ***,with such a plug structure inside,individual lattices can switch the orientation of asymmetry and thus achieve reprogrammable design of a mechanical structure with chained *** reprogrammable asymmetry of this material will offer multiple functions in design of mechanical metamaterials.

关键词： Janus Non-reciprocity Programmability Mechanical metamaterial

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Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb,Polygonum multiflorum

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Frontiers of Medicine 2021年第2期15卷 330-332页

作者： Chunyu li Ming Niu Zhaofang Bai Congen Zhang Yanling Zhao ruiyu li Can Tu Huifang li Jing Jing Yakun Meng Zhijie Ma Wuwen Feng Jinfa Tang Yun Zhu Jinjie li Xiaoya Shang Zhengsheng Zou Xiaohe Xiao Jiabo Wang China Military Institute of Chinese Medicine 302 Military HospitalBeijing 100039China Institute of Medicinal Plant Development Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100193China Integrative Medical Center 302 Military HospitalBeijing 100039China Beijing Friendship Hospital Capital Medical UniversityBeijing 100050China Diagnosis and Treatment Center for Non-infectious Diseases 302 Military HospitalBeijing 100039China Beijing Union University Beijing 100101China Shanxi University of Traditional Chinese Medicine Taiyuan 030619China

Erratum to Frontiers of Medicine 201711(2):253–265 https://***/10.1007/s11684-017-0508-9 The original version of this article unfortunately contained some *** panel of“LPS–/drug–”in Fig.3B(Page 259),the panels of“LPS–/EtoAc+”and“LPS–/Residue+”in Supplementary Fig.3(Page 7 in the online supplementary materials)should be *** authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.

关键词： Medicine hepato corrected

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A Novel Model Predictive Control on Single Phase Inverters for Reducing THD

A Novel Model Predictive Control on Single Phase Inverters f...

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第37届中国控制会议

作者： Po li ruiyu li Xia lin Haifeng Feng Department of Instrumental Electrical Engineering School of Aerospace Engineering Xiamen University Shenzhen Research Institute of Xiamen University

Inverters are commonly used in renewable energy systems as interface. Total Harmonic Distortion（THD） is a key index of judging its effectiveness. In this paper, a direct THD oriented MPC method is proposed. Firstly, a cost function which is a linear combination of DC bias, fundamental frequency deviation and THD of one cycle（20 ms at50 Hz） is designed and the weight factors are obtained by offline calculation. Secondly, the iterative algorithm of cost function is derived to ensure real time control. Then, the switching states as the control law from the finite control set of the input by solving a finite horizon optimization problem is chosen. Simulation results under MATLAB/Simulink show that the proposed method has better performance than the traditional standard error oriented MPC method.

关键词： Total Harmonic Distortion reducing model predictive control single phase inverter modified cost function

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Genomic characterization reveals distinctmutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract

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Cancer Communications 2022年第12期42卷 1367-1386页

作者： Huanwen Wu Zicheng Yu Yueping liu Lei Guo lianghong Teng lingchuan Guo li liang Jing Wang Jie Gao ruiyu li ling Yang Xiu Nie Dan Su Zhiyong liang Department of Pathology State Key Laboratory of Complex Severe and Rare DiseasesMolecular Pathology Research CenterPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730P.R.China Geneplus-Beijing Beijing 102200P.R.China Department of Pathology The Fourth Hospital of Hebei Medical UniversityShijiazhuangHebei 050011P.R.China Department of Pathology Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021P.R.China Department of Pathology Xuanwu HospitalCapital Medical UniversityBeijing 100053P.R.China Department of Pathology The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215000P.R.China Department of Pathology Southern Medical UniversityGuangzhouGuangdong 510515P.R.China Department of Pathology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022P.R.China Department of Pathology The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer(IBMC)Chinese Academy of SciencesHangzhouZhejiang 310022P.R.China

Background:Neuroendocrine carcinomas of the gastrointestinal tract(GINECs)remain a disease of grim prognosis with limited therapeutic *** molecular characteristics are still *** study aimed to explore the underlying genetic basis and heterogeneity of ***:Comprehensive genomic analysis using whole-exome sequencing was performed on 143 formalin-fixed,paraffin-embedded samples of surgically resected GI-NEC with a thorough histological *** signatures,somatic mutations,and copy number aberrations were analyzed and compared across anatomic locations and histological *** analysis was conducted to identify the independent ***:In total,143GI-NECswere examined:the stomach,87 cases(60.8%);the esophagus,29 cases(20.3%);the colorectum,20 cases(14.0%);and the small intestine,7 cases(4.9%).Eighty-three(58.0%)and 60(42.0%)cases were subclassified into small cell and large cell subtypes,***-NECs showed distinct genetic alterations from their lung counterparts and non-neuroendocrine carcinomas in the same *** heterogeneity of mutational signatures,somatic mutations,and copy number variations was revealed across anatomic locations rather than histological *** for tumor protein p53(TP53)and retinoblastoma 1(RB1),the most frequently mutated genes in the stomach,esophagus,colorectum,and small intestine were low-density lipoprotein receptor-related protein 1B(LRP1B),notch receptor 1(NOTCH1),adenomatosis polyposis coli(APC),catenin beta 1(CTNNB1),*** in the WNT-β-catenin,NOTCH and erythroblastic leukemia viral oncogene B(ERBB)pathwayswere prevalently identified in gastric,esophageal,and colorectalNECs,***,104(72.7%)GI-NECs harbored putative clinically relevant alterations,and non-gastric location and RB1 bi-allelic inactivation with copy number alterations were identified as two independent poor prognostic ***,we found th

关键词： Neuroendocrine carcinomas Gastrointestinal tract Genomic characterization Heterogeneity Therapeutic implications

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Si-Wu-Tang attenuates liver fibrosis via regulating lncRNA H19-dependent pathways involving cytoskeleton remodeling and ECM deposition

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Chinese Journal of Natural Medicines 2024年第1期22卷 31-46页

作者： QU Jiaorong XUE Xiaoyong WANG Zhixing MA Zhi JIA Kexin li Fanghong ZHANG Yinhao WU ruiyu ZHOU Fei ZHAO Piwen li Xiaojiaoyang School of life Sciences Beijing University of Chinese MedicineBeijing 100029China School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing 100029China State Key Laboratory of Medical Molecular Biology Department of Molecular Biology and BiochemistryInstitute of Basic Medical SciencesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100005China

liver fibrosis is a dynamic wound-healing response characterized by the agglutination of the extracellular matrix(ECM).Si-Wu-Tang(SWT),a traditional Chinese medicine(TCM)formula,is known for treating gynecological diseases and liver *** previous studies demonstrated that long non-coding RNA H19(H19)was markedly upregulated in fibrotic livers while its deficiency markedly reversed ***,the mechanisms by which SWT influences H19 remain ***,we established a bile duct ligation(BDL)-induced liver fibrosis model to evaluate the hepatoprotective effects of SWT on various cells in the *** results showed that SWT markedly improved ECM deposition and bile duct reactions in the ***,SWT relieved liver fibrosis by regulating the transcription of genes involved in the cytoskeleton remodeling,primarily in hepatic stellate cells(HSCs),and influencing cytoskeleton-related angiogenesis and hepatocellular *** modulation collectively led to reduced ECM *** extensive bioinformatics analyses,we determined that H19 acted as a miRNA sponge and mainly inhibited miR-200,miR-211,and let7b,thereby regulating the above cellular regulatory ***,SWT reversed H19-related miRNAs and signaling pathways,diminishing ECM deposition and liver ***,these protective effects of SWT were diminished with the overexpression of H19 in *** conclusion,our study elucidates the underlying mechanisms of SWT from the perspective of H19-related signal networks and proposes a potential SWT-based therapeutic strategy for the treatment of liver fibrosis.

关键词： liver fibrosis LncRNA H19 Si-Wu-Tang miRNAs Cytoskeleton ECM deposition

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The quality control and hypoglycemic effect of Cinnamomi Cortex aqueous extract

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Journal of Future Foods 2024年第2期4卷 167-172页

作者： Xuting Hao Ziheng Jin ruiyu Gao Shiming li Changqin li lijun liu Jinmei Wang National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Key Laboratory of Natural Pigment Preparation of Henan Province Luohe 462600China Department of Food Science Rutgers University New BrunswickNJ 08901USA Joint International Research Laboratory of Food&Medicine Resource Function of Henan Province Kaifeng 475004China Huaihe Hospital of Henan University Kaifeng 475000China

Cinnamomi Cortex was a material as medicinal and edible resources and it has been demonstrated that Cinnamomi Cortex aqueous extract(CCAE)possess hypoglycemic effect,but there were no active compounds identified as quality standard of CCAE to be used in the investigate of hypoglycemic ***,in this study,the quality standard and the hypoglycemic effect of CCAE were *** and coumarin as the quality control in CCAE were analyzed by high performance liquid chromatography(HPLC)*** results showed that the average yield of extraction was 10.06%.The concentration of coumarin was linear with peak area ranging from 0.02–1.00μg/mL(r=0.9996,n=6)and that of cinnamaldehyde also demonstrated a good linear relationship with peak area in the range of 1.05–52.50μg/mL(r=0.9997,n=6).The average recovery rate of coumarin and cinnamaldehyde was 99.42%and 100.11%,*** investigation of hypoglycemic effect revealed that CCAE could improve weight loss,lower liver and pancreas indices,improve organ damage caused by diabetes,and lower fasting blood glucose,glycosylated serum protein(GSP)and total cholesterol(TC)*** results showed that CCAE can reduce fasting blood glucose and blood lipid levels in diabetic mice.

关键词： Cinnamomi Cortex Cinnamaldehyde Coumarin Hypoglycemic effect

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叶根倒角对跨音轴流压气机气动性能的影响

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机械工程学报 2016年第20期52卷 137-143页

作者：高丽敏蔡宇桐李萍李瑞宇西北工业大学动力与能源学院西安710072 先进航空发动机协同创新中心北京100191

为了获得叶根倒角对跨音轴流压气机气动特性影响规律,研究充分考虑了加工工艺及气动影响两方面,用倒角半径及最小角度两个参数确定倒角几何。研究基于Rotor37分析倒角参数对叶片几何的影响,并从整体性能及内部流场细节两方面对转子气动... 详细信息

为了获得叶根倒角对跨音轴流压气机气动特性影响规律,研究充分考虑了加工工艺及气动影响两方面,用倒角半径及最小角度两个参数确定倒角几何。研究基于Rotor37分析倒角参数对叶片几何的影响,并从整体性能及内部流场细节两方面对转子气动特性变化进行详细分析,获得了倒角参数变化对气动性能的影响规律。研究结果表明,相对于最小角度,倒角半径是影响转子性能的主要因素;倒角的存在不仅使得叶片根部马蹄涡的分布发生改变,且影响了出口通道涡的强度和尺度。此外倒角存在改变了叶根处的压力分布,使得前缘来流附面层有所增厚,导致根部的做功能力及转子性能下降。

关键词： Rotor37 叶根倒角刀具干涉最小角度数值模拟

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