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FLOATING RATE OF FRAZIL ICE PARTICLES IN FLOWING WATER IN BEND CHANNELS——A THREE-DIMENSIONAL NUMERICAL ANALYSIS

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Journal of Hydrodynamics 2010年第1期22卷 19-28页

作者： WANG jun li qing-gang SUI Jue-yi School of Civil Engineering Hefei University of Technology Hefei 230009 China Environmental Engineering Program University of Northern British Columbia British Columbia Canada V2N4V9

In this article, based on the theory of two-phase flow and laboratory data, a three-dimensionally model is developed to simulate the floating rates of frazil ice particles in water under covered condition. The Lagrangian trajectory method is used in the three dimensional simulation for floating rates of fxazil ice particles along a 180° bend channel. The velocity profiles in longitudinal and transverse directions, the turbulence intensity, and the residual pressure are simulated. Under the condition of gravitational similarity, the simulated floating rates of frazil ice particles in the model bend channel and the prototype bend channels are compared. Results indicate that the profiles for floating rates of ice particles for flows in the model channel are similar to those in the prototype bend channels. The simulated floating rates of ice particles are clearly higher along the convex bank than along the concave bank at each cross section. For the prototype bend channel in a large model scale, the variation of floating rate across each cross section is relatively small.

关键词： frazil ice particles model scale floating rate two-phase flow bend channel ice accumulation (ice jam)

Landslide susceptibility assessment of the region affected by the 25 April 2015 Gorkha earthquake of Nepal

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Journal of Mountain Science 2016年第11期13卷 1941-1957页

作者： Amar Deep Regmi Megh Raj Dhital ZHANG Jian-qiang SU li-jun CHEN Xiao-qing Key Laboratory of Mountain Hazards and Earth Surface Process Institute of Mountain Hazards and EnvironmentCASChengdu 610041China Central Department of Geology Tribhuvan UniversityKirtipur 44613Nepal

Nepal was hit by a 7.8 magnitude earthquake on 25^(th) April,*** main shock and many large aftershocks generated a large number of coseismic landslips in central *** have developed a landslide susceptibility map of the affected region based on the coseismic landslides collected from remotely sensed data and fieldwork,using bivariate statistical model with different landslide causative *** the investigation,it is observed that most of the coseismic landslides are independent of previous *** of 3,716 mapped landslides,we used 80% of them to develop a susceptibility map and the remaining 20% were taken for validating the model.A total of 11 different landslide-influencing parameters were *** include slope gradient,slope aspect,plan curvature,elevation,relative relief,Peak Ground Acceleration(PGA),distance from epicenters of the mainshock and major aftershocks,lithology,distance of the landslide from the fault,fold,and drainage *** success rate of 87.66% and the prediction rate of86.87% indicate that the model is in good agreement between the developed susceptibility map and theexisting landslides ***,lithology,slope angle and elevation have played a major role in triggering the coseismic mass *** susceptibility map can be used for relocating the people in the affected regions as well as for future land development.

关键词： Earthquake Himalaya Coseismic landslide Susceptibility bivariate statistical model Nepal

Systematic Study on Alpha Decay Half-lives of Superheavy Nuclei

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Communications in Theoretical Physics 2007年第3X期48卷 545-552页

作者： ZHANG Hong-Fei li jun-qing ZUO Wei ZHOU Xiao-Hong GAN Zai-Guo School of Nuclear Science and Technology Lanzhou University Lanzhou 730000 China Institute of Modern Physics the Chinese Academy of Sciences Lanzhou 730000 China Research Center of Nuclear Theory of Laboratory of Heavy Ion Accelerator of Lanzhou Lanzhou 730000 China

The α-decay half-lives of a set of superheavy nuclear isotope chain from Z = 105 to 120 have been analyzed systematically within the WKB method, and some nuclear structure features are found. The decay barriers have been determined in the quasi-molecular shape path within the Generalized liquid Drop Model （GLDM） including the proximity effects between nucleons in a neck and the mass and charge asymmetry. The results are in reasonable agreement with the published experimental data for the alpha decay half-llves of isotopes of charge 112, 114, and 116, of the element 294118 and of some decay products. A comparison of present calculations with the results by the DDM3Y effective interaction and by the Viola-Seaborg-Sobiczewski （VSS） formulae is also made. The experimental a decay half lives all stand in between the GLDM calculations and VSS formula results. This demonstrates the possibility of these models to provide reasonable estimates for the half-lives of nuclear decays by a emissions for the domain of SHN. The half-lives of these new nuclei are thus well tested from the reasonable consistence of the macroscopic, the microscopic, the empirical formulae and the experimental data. This also shows that the present data of SHN themselves are consistent. It could suggest that the present experimental claims on the existence of new elements Z =110 - 118 are reliable. It is expected that greater deviations of a few SHN between the data and the model may be eliminated by further improvements on the precision of the measurements.

关键词： superheavy nucleus alpha decay life time

Gound State Properties of Nuclei in ^(295)118 α-Decay Chain

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Communications in Theoretical Physics 2009年第12期52卷 1055-1061页

作者： DONG Jian-Min ZHANG Hong-Fei ZUO Wei WANG Yan-Zhao li jun-qing School of Nuclear Science and Technology Lanzhou University Lanzhou 730000 China Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 China

The properties of nuclei belonging to the α-decay chain of superheavy element ^295118 have been studied in the framework of axially deformed relativistic mean field （RMF） theory with the parameter set of NL-Z2 in the blocked BCS approximation. Some ground state properties such as binding energies, deformations, and α-decay energies Qα have been obtained and agree well with those from finite-range droplet model （FRDM）. The single-particle spectra of nuclei in ^295118 α-decay chain show that the shell gaps present obviously nucleon number dependence. The root-mean-square （rms） radii of proton, neutron and matter distributions change slowly from ^283112 to ^295118 but dramatically from ^279110 to ^283112, which may be due to the subshell closure at Z = 110 in ^279110. The α-decay half-lives in 295118 decay chain are evaluated by employing the cluster model and the generalized liquid drop model （GLDM）, and the overall agreement is found when they are compared with the known experimental data. The α-decay lifetimes obtained from the cluster model are slightly larger than those of GLDM ones. Finally, we predict the α-decay half-lives of Z=118, 116, 114, 112 isotopes using the cluster model and GLDM, which also indicate these two models can corroborate each other in studies on superheavy nuclei. The results from GLDM are always lower than those obtained from the cluster model.

关键词： superheavy nuclei relativistic mean field half-lives cluster model generalized liquid drop model

Ground-State Properties of Z=59 Nuclei in the Relativistic Mean-Field Theory

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Chinese Physics Letters 2000年第3期17卷 185-187页

作者： ZHOU Yong MA Zhong-Yu CHEN Bao-Qiu li jun-qing Research Center of Nuclear Theory of National Laboratory of Heavy Ion Accelerator of Lanzhou Lanzhou 730000 Institute of Modern Physics the Chinese Academy of SciencesLemzhou 730000 China Institute of Atomic Energy Beijing 102413

Ground-state properties of Pr isotopes are studied in a framework of the relativistic mean-field(RMF)theory using the recently proposed parameter set ***-Cooper-Schrieffer(BCS)approximation and blocking method is adopted to deal with pairing interaction and the odd nucleon,*** pairing forces are taken to be isospin *** domain of the validity of the BCS theory and the positions of neutron and proton drip lines are *** is shown that RMF theory has provided a good description of the binding energyf isotope shifts and deformation of nuclei over a large range of Pr isotopes,which are in good agreement with those obtained in the finite-range droplet model.

关键词： theory positions validity

Biological Evaluation of Lysionotin:a Novel Inhibitor of 5-lipoxygenase for Anti-glioma

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Chinese Journal of Integrative Medicine 2024年第9期30卷 826-834页

作者： SHAO Xin-xin CHEN Cong liU Jie li qing-jun HE Shan QI Xiang-hua FU Xian-jun WANG Zhen-guo The First Clinical College of Medicine Shandong University of Traditional Chinese MedicineJinan250355China Institute for literature and Culture of Chinese Medicine Shandong University of Traditional Chinese MedicineJinan250355China Key Laboratory of Classical Theory of Traditional Chinese Medicine Ministry of EducationShandong University of Traditional Chinese MedicineJinan250355China College of Pharmacy Shandong University of Traditional Chinese MedicineJinan250355China Experimental Center Shandong University of Traditional Chinese MedicineJinan250355China Neurology Department Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan250014China Marine Traditional Chinese Medicine Research Center Qingdao Academy of Traditional Chinese MedicineShandong University of Traditional Chinese MedicineQingdao266114Shandong ProvinceChina

Objective:To explore the potential mechanism of lysionotin in treating ***:First,target prediction based on Bernoulli Naïve Bayes profiling and pathway enrichment was used to predict the biological activity of *** binding between 5-lipoxygenase(5-LO)and lysionotin was detected by surface plasmon resonance(SPR)and molecular docking,and the inhibitory effects of lysionotin on 5-LO and proliferation of glioma were determined using enzyme inhibition assay in vitro and cell viability analysis,***,the pharmaceutical effect of lysionotin was explored by cell survival rate analysis and liquid chromatography with tandem mass spectrometry(LC-MS/MS).The protein expression,intracellular calcium ion concentration and cytoskeleton detection were revealed by Western blot,flow cytometry and fluorescence labeling,***:Target prediction and pathway enrichment revealed that lysionotin inhibited 5-LO,a key enzyme involved in the arachidonic acid metabolism pathway,to inhibit the proliferation of *** docking results demonstrated that 5-LO can be binding to lysionotin through hydrogen bonds,forming bonds with His600,Gln557,Asn554,and *** analysis further confirmed the interaction between 5-LO and ***,enzyme inhibition assay in vitro and cell survival rate analysis revealed that 50%inhibition concentration of lysionotin and the median effective concentration of lysionotin were 90 and 16.58µmol/L,respectively,and the results of LC-MS/MS showed that lysionotin inhibited the production of 5S-hydroperoxy-eicosatetraenoic acid(Plioma cells well(P<0.01)and inhibit their *** blot analysis demonstrated that lysionotin can inhibit the expression of 5-LO(P<0.05)and downstream leukotriene B4 receptor(P<0.01).In addition,the results showed that lysionotin affected intracellular calcium ion concentration by inh

关键词： 5-lipoxygenase inhibitor lysionotin 5-lipoxygenase leukotriene B4 calcium ion cytoskeleton

Theoretical Study on Properties of New Isotope 265Bh

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Communications in Theoretical Physics 2006年第4期45卷 681-686页

作者： ZHANG Hong-Fei ZUO Wei li jun-qing Soojae Im MA Zhong-Yu CHEN Bao-Qju Institute of Modern Physics the Chinese Academy of Sciences Lanzhou 730000 China Graduate School of＇the Chinese Academy of Sciences Beijin 100049 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 China Institut für Theoretische Physik Justus-Liebig-Universitaet Heinrich-Buff-Ring 16 D 35392 Giessen Germany China Institute of Atomic Energy Beijing 102413 China

The properties of nuclei belonging to the newly observed α-decay chain starting from ^265Bh have been studied. The axially deformed relativistic mean-field calculation with the force NL-Z2 has been performed in the blocked BCS approximation. Some ground state properties such as binding energies, deformations, spins, and parities, as well as Q-values of the a-decay for this decay chain have been calculated and compared with known experimentai data. Good agreement is found. The slngle-particle spectrum of the nucleus ^265Bh is studied and some new magic numbers are found, while the magnitudes of the shell gaps in superheavy nuclei are much smaller than those of nuclei before the actinium region, and the Fermi surfaces are close to the continuum. Thus the superheavy nuclei are usually not stable. The a-decay lifetimes in the ^265Bh decay chain are evaluated by different formulae, and compared with experimental data. The methods which give good agreement with the data are selected.

关键词： relativistic mean field superheavy nuclei binding energy lifetimes

The Role of Potential Structure in Excitation Functions of Synthesizing Superheavy Nuclei

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Communications in Theoretical Physics 2007年第4X期48卷 713-716页

作者： JIA Fei HUANG Tian-Heng XU Hu-Shan li jun-qing WANG Nan W. Scheid Institute of Modern Physics the Chinese Academy of Sciences Lanzhou 730000 China Research Center of Nuclear Theory of Laboratory of Heavy Ion Accelerator of Lanzhou Lanzhou 730000 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China Department of Physics College of Science Shenzhen University Shenzhen 518060 China Institut fuer Theoretische Physik Justus-Liebig-Universitaet 35392 Giessen Germany

The excitation functions of two very similar reaction channels, 58Fe＋ 208pb→ 265Hs ＋ 1n and 58Fe＋ 209Bi → 266Mt ＋1n are studied in the framework of the dinuclear system conception. The fusion probabilities are found to be strongly subject to the structure of the driving potential. Usually the fusion probability is hindered by a barrier from the injection channel towards the compound nuclear configuration. The barrier towards the mass symmetrical direction, however, also plays an important role for the fusion probability, because the barrier hinders the quasi-fission, and therefore helps fusion.

关键词： superheavy nuclei driving potential excitation function

Design, Synthesis and Biological Evaluation of Non-azole Inhibitors of Lanosterol 14α-Demethylase of Fungi

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Chinese Chemical Letters 2006年第9期17卷 1189-1192页

作者： Bin YAO You jun ZHOU Jü ZHU Jia Guo Lü Yao Wu li jun CHENG qing Feng JIANG Can Hui ZHENG School of Pharmacy Second Military Medicial University Shanghai 200433

Novel tetralin compounds were designed and synthesized on the three-dimensional model of lanosterol 14α-demethylase of Candida albicans. All of the lead compounds exhibited potent antifungal activities, especially compounds 16, 20. The mode of the action of the lead compounds was different from that of azoles. The present study affords the possibility to develop novel antifungal agents that specifically interact with the amino acid residues in the active site and avoid the serious toxicity arising from coordination binding with the heme of mammalian P450s.

关键词： Antifungal 2-aminotetralins lanosterol 14α-demethylase inhibitor.