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Development of EPDM composites reinforced by CNTs@SiO_(2)for thermal protection systems of aerospace propulsion:Significant improvement in oxidation and ablation resistance properties

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Chinese Journal of Aeronautics 2024年第2期37卷 471-481页

作者： li WANG jiang li Kang li Yiwei WANG Chenyang MA Science and Technology on Combustion Internal Flow and Thermal-Structure LaboratoryNorthwestern Polytechnical UniversityXi’an 710072China

Carbon Nanotubes(CNTs)reinforced Polymer-Matrix Composites(PMCs)is widely used as insulation materials in thermal protection system of aerospace ***,CNTs are prone to oxidation and have high thermal conductivities,which makes it difficult to improve the ablation resistance of insulation materials that contain ***_(2)was encapsulated onto the surface of CNTs(CNTs@SiO_(2)),which were then added to Ethylene Propylene Diene Monomer(EPDM)rubber to prepare the insulation *** analysis and ablation test were used to evaluate the resistance of the insulation materials to thermal oxidation and ***,scanning electron microscopy was performed to analyze their *** revealed that the addition of CNTs@SiO_(2)could visibly reduce the effects of hot corrosion and ablation on insulation *** C-CNTs@SiO_(2)-1 formulation had the best ablative ***,compared with the unencapsulated formulation(C-CNTs-10),the C-CNTs@SiO_(2)-1 formulation reduced the line ablation rate by 51%to 0.0130 mm/s after oxygen-acetylene ***,the ablation mechanism was investigated based on the effects of the CNTs@SiO_(2)additive on their ***,the improvement in ablation performance may be attributed to CNTs@SiO_(2)-induced decreases in thermal conductivity,improvement in the hot corrosion resistance in the char layer,and changes in the microstructure.

关键词： Polymer-Matrix Composites(PMCs) Carbon Nanotubes(CNTs) Thermal properties Ablation Oxidation

Effect of miR-124 Overexpression under Wnt/β-catenin Signaling Pathway on Inflammatory Factor and Epidermal Growth Factor in Rats with Precancerous Gastric Lesions

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Chinese Journal of Biomedical Engineering 2024年第1期33卷 17-26页

作者： ZHOU li-jiang Zhejiang Chinese Medical University Shangyu People's Hospital of Shaoxing

Objective: To investigate the effects of miR-124 overexpression on inflammatory factors and epidermal growth factor in rats with gastric precancerous lesions by modulating the Wnt/β-catenin signaling pathway. Methods: Eighty SPF-grade Wistar rats were selected as the research subjects. After adaptive feeding,they were divided into 4 groups using a random number table method. The control group was fed a regular diet, while the model group, low expression group, and overexpression group of rats were treated with N-methyl-N'-nitro-N-nitrosoguanidine to establish a model of gastric cancer precancerous lesions. After successful modeling, the control group and model group rats were injected intraperitoneally with 0.9% sodium chloride solution, the low-expression group rats were injected intraperitoneally with miR-124-5p inhibitor, and the over-expression group rats were injected intraperitoneally with miR-124-5p mimic. After 8 weeks of continuous injection, the levels of miR-124,Wnt/β-catenin signaling pathway-related proteins, inflammatory factors, and epidermal growth factor were observed and compared among the four groups of rats. Results: The differences in the relative expression of miR-124 among the four groups of rats were statistically significant(P<0.05); the differences in the expression of Wnt protein andβ-catenin protein among the four groups of rats were statistically significant(P<0.05),and the expression of Wnt protein and β-catenin protein in the overexpression group was significantly higher than that of the control group, and significantly lower than that in the model group and the low-expression group; the levels of IL-1β, IL-6, and TNF-αof rats in the four groups of rats IL-1β, IL-6 and TNF-α levels were statistically different(P<0.05), and the levels of IL-1β, IL-6 and TNF-α in rats in the overexpression group were higher than those in the model group and significantly lower than those in the model group and the low-expression group(P<0.05); the differ

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EmotionIC: emotional inertia and contagion-driven dependency modeling for emotion recognition in conversation

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Science China(Information Sciences) 2024年第08期67卷 130-146页

作者： Yingjian liU jiang li Xiaoping WANG Zhigang ZENG School of Artificial Intelligence and Automation Huazhong University of Science and Technology Hubei Key Laboratory of Brain-inspired Intelligent Systems Huazhong University of Science and Technology Key Laboratory of Image Processing and Intelligent Control (Huazhong University of Science and Technology) Ministry of Education Institute of Artificial Intelligence Huazhong University of Science and Technology

Emotion recognition in conversation(ERC) has attracted growing attention in recent years as a result of the advancement and implementation of human-computer interface technologies. In this paper,we propose an emotional inertia and contagion-driven dependency modeling approach(EmotionIC) for ERC tasks. Our EmotionIC consists of three main components, i.e., identity masked multi-head attention(IMMHA), dialogue-based gated recurrent unit(DiaGRU), and skip-chain conditional random field(SkipCRF).Compared to previous ERC models, EmotionIC can model a conversation more thoroughly at both the feature-extraction and classification levels. The proposed model attempts to integrate the advantages of attention-and recurrence-based methods at the feature-extraction level. Specifically, IMMHA is applied to capture identity-based global contextual dependencies, while Dia GRU is utilized to extract speaker-and temporal-aware local contextual information. At the classification level, SkipCRF can explicitly mine complex emotional flows from higher-order neighboring utterances in the conversation. Experimental results show that our method can significantly outperform the state-of-the-art models on four benchmark *** ablation studies confirm that our modules can effectively model emotional inertia and contagion.

关键词： emotion recognition in conversation emotional inertia and contagion multi-head attention gated recurrent unit conditional random field

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A booming field of large animal model research

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Zoological Research 2024年第2期45卷 311-313页

作者： Xiao-jiang li liangxue Lai Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)GHM Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong 510632China State Key Laboratory of Bioactive Molecules and Druggability Assessment Jinan UniversityGuangzhouGuangdong 510632China CAS Key Laboratory of Regenerative Biology Guangdong Provincial Key Laboratory of Stem Cell and Regenerative MedicineGuangzhou Institutes of Biomedicine and HealthChinese Academy of SciencesGuangzhouGuangdong 510530China

Animal models are integral to the study of fundamental biological processes and the etiology of human *** animal models,especially those involving mice,have yielded abundant and significant insights,greatly enhancing ... 详细信息

关键词： mechanisms insight field

Effect of Y substitution on the microstructure,magneto-optical,and thermal properties of(Tb_(1−x)Y_(x))_(3)Al_(5)O_(12)transparent ceramics

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Journal of Advanced Ceramics 2024年第4期13卷 529-538页

作者： lixuan Zhang Dianjun Hu Xiao li Ziyu liu Chen Hu Lexiang Wu Tingsong li Dariusz Hreniak jiang li Transparent Ceramics Research Center Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 201899China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou 341000China Institute of Low Temperature and Structure Research Polish Academy of SciencesWroclaw 50-422Poland

Faraday isolators can prevent the front-end system from disturbance and damage caused by a back-reflected beam,so they are important elements in laser *** magneto-optical materials are the most important component in Faraday isolators,the studies on magneto-optical materials have attracted much attention these ***_(3)Al_(5)O_(12)(TAG)ceramics are considered to be one of the most promising magneto-optical materials for visible to near-infrared wavelength band application because of their outstanding comprehensive magneto-optical ***,the optical quality of TAG ceramics needs further optimization to meet the application *** this work,high optical quality(Tb_(1−x)Y_(x))_(3)Al_(5)O_(12)(x=0,0.05,0.1,0.2,and 0.3)magneto-optical ceramics were fabricated successfully by solid-state reaction sintering combined with hot isostatic pressing(HIP)*** the ceramics obtained showed a single garnet phase for different values of x in the range *** addition of Y_(2)O_(3) was found to suppress the secondary phase and improve optical quality *** ceramic samples obtained had clear grain boundaries and possessed the in-line transmittance values of 82.9%at 1064 nm and 82.2%at 633 nm,*** Verdet constants of(Tb_(1−x)Y_(x))_(3)Al_(5)O_(12)ceramics with x=0,0.05,0.1,0.2,and 0.3 were−188.1,−175.4,−168.5,−143.0,and−119.9 rad/(T·m),*** thermal conductivity of TAG ceramics was found to be 5.23 W/(m·K)at 25℃,and when 20%Y was substituted in place of Tb,the thermal conductivity decreased by only 9.4%.

关键词： (Tb_(1−x)Y_(x))_(3)Al_(5)O_(12)ceramics magneto-optical materials optical quality thermal properties

Large animal models for Huntington's disease research

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Zoological Research 2024年第2期45卷 275-283页

作者： Bofeng Han Weien liang Xiao-jiang li Shihua li Sen Yan Zhuchi Tu Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan University Key Laboratory of CNS Regeneration(Jinan University)-Ministry of EducationGuangdong Key Laboratory of Non-Human Primate ResearchGuangzhouGuangdong 510632China Department of Pathophysiology School of MedicineJinan UniversityGuangzhouGuangdong 510632China

Huntington'sdisease(HD)isahereditary neurodegenerative disorder for which there is currently no ***,the development of appropriate disease models is critical to thoroughly investigate disease *** genetic basis of HD involves the abnormal expansion of CAG repeats in the huntingtin(HTT)gene,leading to the expansion of a polyglutamine repeat in the HTT *** HTT carrying the expanded polyglutamine repeat undergoes misfolding and forms aggregates in the brain,which precipitate selective neuronal loss in specific brain *** models play an important role in elucidating the pathogenesis of neurodegenerative disorders such as HD and in identifying potential therapeutic *** to the marked species differences between rodents and larger animals,substantial efforts have been directed toward establishing large animal models for HD *** models are pivotal for advancing the discovery of novel therapeutic targets,enhancing effective drug delivery methods,and improving treatment *** have explored the advantages of utilizing large animal models,particularly pigs,in previous *** then,however,significant progress has been made in developing more sophisticated animal models that faithfully replicate the typical pathology of *** the current review,we provide a comprehensive overview of large animal models of HD,incorporating recent findings regarding the establishment of HD knock-in(KI)pigs and their genetic *** also explore the utilization of large animal models in HD research,with a focus on sheep,non-human primates(NHPs),and *** objective is to provide valuable insights into the application of these large animal models for the investigation and treatment of neurodegenerative disorders.

关键词： Huntington's disease Large animal models Sheep Non-human primates Transgenic pigs

Research on Flexible Job Shop Scheduling Based on Improved Two-Layer Optimization Algorithm

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Computers, Materials & Continua 2024年第1期78卷 811-843页

作者： Qinhui liu Laizheng Zhu Zhijie Gao Jilong Wang jiang li College of Mechanical and Electrical Engineering Harbin Engineering UniversityHarbin150001China

To improve the productivity,the resource utilization and reduce the production cost of flexible job shops,this paper designs an improved two-layer optimization algorithm for the dual-resource scheduling optimization problem of flexible job shop considering workpiece ***,a mathematical model is established to minimize the maximum completion ***,an improved two-layer optimization algorithm is designed:the outer layer algorithm uses an improved PSO(Particle Swarm Optimization)to solve the workpiece batching problem,and the inner layer algorithm uses an improved GA(Genetic Algorithm)to solve the dual-resource scheduling ***,a rescheduling method is designed to solve the task disturbance problem,represented by machine failures,occurring in the workshop production ***,the superiority and effectiveness of the improved two-layer optimization algorithm are verified by two typical *** case results show that the improved two-layer optimization algorithm increases the average productivity by 7.44% compared to the ordinary two-layer optimization *** setting the different numbers of AGVs(Automated Guided Vehicles)and analyzing the impact on the production cycle of the whole order,this paper uses two indicators,the maximum completion time decreasing rate and the average AGV load time,to obtain the optimal number of AGVs,which saves the cost of production while ensuring the production *** research combines the solved problem with the real production process,which improves the productivity and reduces the production cost of the flexible job shop,and provides new ideas for the subsequent research.

关键词： Dual resource scheduling workpiece batching rescheduling particle swarm optimization genetic algorithm

Effect of Maternal DEHP Exposure on lipid Metabolism in Adult Male Rats and the Antagonistic Effect of Genistein

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Biomedical and Environmental Sciences 2024年第3期37卷 315-319页

作者： ZHANG Yun Bo li jiang li TIAN Jie NA Xiao lin Department of Environmental Hygiene Public Health CollegeHarbin Medical UniversityHarbin 150081HeilongjiangChina

lipid metabolism refers to the biochemical processes involved in synthesising,storing,utilising,and breaking down lipids in living *** are essential for various physiological functions,including energy storage,insulation,protection of organs,and the formation of cell *** in lipid metabolism can lead to a number of health issues,such as atherosclerosis,obesity,and type 2 diabetes,etc.[1].Environmental factors,genetics,and lifestyle factors are some of the factors that can contribute to the development of ***,there is a growing academic interest in the impact of environmental factors.

关键词： lipid metabolism organs

The Effect of Blending Ratio on the Structure and Properties of the PPR/PS In situ Fiber Reinforced System Prepared by Multi-Flow Vibration Injection Molding

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Chinese Journal of Polymer Science 2024年第6期42卷 851-863页

作者： Yan-jiang li Meng-Long Hu Jun-Wen Zhang Qiang Fu Jie Zhang College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China

To enhance the mechanical properties of polypropylene random copolymer(PPR),polystyrene(PS)with four different contents were added to the PPR matrix through melt ***,using the Multi-Flow Vibration Injection Molding(MFVIM)technology,PPR/PS in situ microfiber composites(MFC)with different blending ratios were *** results indicated that blending ratio had a great impact on the phase morphology and crystal structure of MFVIM samples,which was different from those of conventional injection molding(CIM)*** ultrafine fibers could be formed under the shear field and could absorb the PPR molecular chains to form hybrid shish-kebab ***,the PPR matrix could also form shish-kebab structures under the effect of strong *** the PS content reached 20%,under the combined action of PS in situ microfibers and highly oriented crystal structure,the tensile strength and Young’s modulus of the sample were obviously improved and the impact strength remained at a relatively high *** a strong and tough balanced PPR based material was *** results provide valuable insights for expanding the industrial and daily-life applications of PPR and show promising development prospects.

关键词： PPR MFVIM In situ microfibers Shearfield Hybrid shish-kebab structures