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Gas microchannel plate-pixel detector for X-ray polarimetry

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Nuclear Science and Techniques 2024年第5期35卷 60-73页

作者： Huan-Bo Feng Hong-Bang liu Dong Wang Zi-li li Shu-lin liu Qian liu Hang-Zhou li Bin-Long Wang Yan-Jun Xie Zong-Wang Fan Hui Wang Ran Chen Di-Fan Yi Rui-Ting Ma fei Xie Bo peng Xiang-Ming Sun Jin li En-Wei liang Present Address:Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China PLAC Key Laboratory of Quark and Lepton Physics(MOE)Central China Normal UniversityWuhan 430079China School of Science Huzhou UniversityHuzhou 313000China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China School of Physical Science University of Chinese Academy of SciencesBeijing 100049China The 13th Research Institute of china Electronics Technology Group Corporation Shijiazhuang 050057China

POLAR-2.is a gamma-ray burst(GRB)polarimeter that is designed to study the polarization in GRB radiation emissions,aiming to improve our knowledge of related ***-2.is expected to utilize an on-board polarimeter that is sensitive to soft X-rays(2.1. keV),called low-energy polarization *** have developed a new soft X-ray polari-zation detector prototype based on gas microchannel plates(GMCPs)and pixel chips(Topmetal).The GMCPs have bulk resistance,which prevents charging-up effects and ensures gain stability during *** detector is composed of low outgassing materials and is gas-sealed using a laser welding technique,ensuring long-term stability.A modulation factor of 41.2.%±0.64% is obtained for a 4.5 keV polarized X-ray beam.A residual modulation of 1.96%±0.58% at 5.9 keV is observed for the entire sensitive area.

关键词： X-ray polarimetry Gas microchannel plate-pixel detector Gamma-ray bursts

Jianpi-Huatan-Huoxue-Anshen formula ameliorates gastrointestinal inflammation and microecological imbalance in chemotherapytreated mice transplanted with H2. hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第10期16卷 4209-4231页

作者： Ya-Nan Wang Xiang-Yang Zhai Zheng Wang Chun-ling Gao Sui-Cai Mi Wen-li Tang Xue-Min Fu Huai-Bang li li-Feng Yue peng-fei li Sheng-Yan Xi department of TCM Xiang’an HospitalSchool of MedicineXiamen UniversityXiamen 361102Fujian ProvinceChina Faculty of Chinese Medicine and State Key Laboratory of Quality Research in Chinese Medicine Macao University of Science and TechnologyMacao 999078China department of Radiotherapy Chenggong Hospital of Xiamen UniversityPLA 73rd Army HospitalXiamen 361003Fujian ProvinceChina department of Oncology Xiamen Hospital of Traditional Chinese MedicineXiamen 361015Fujian ProvinceChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijing 100700China

BACKGROUND Jianpi-Huatan-Huoxue-Anshen formula[Tzu-Chi cancer-antagonizing&lifeprotecting II decoction(TCCL)]is a Chinese medical formula that has been clinically shown to reduce the gastrointestinal side effects of chemotherapy in cancer patients and improve their quality of ***,its effect and mechanism on the intestinal microecology after chemotherapy are not yet *** To discover the potential mechanisms of TCCL on gastrointestinal inflammation and microecological imbalance in chemotherapy-treated mice transplanted with hepatocellular carcinoma(HCC).METHODS Ninety-six mice were inoculated subcutaneously with HCC *** week later,the mice received a large dose of 5-fluorouracil by intraperitoneal injection to establish a HCC chemotherapy ***-six mice were randomly selected before administration,and feces,ileal tissue,and ileal contents were collected from each *** remaining mice were randomized into normal saline,continuous chemotherapy,Yangzheng Xiaoji capsulestreated,and three TCCL-treated *** treatment,feces,tumors,liver,spleen,thymus,stomach,jejunum,ileum,and colon tissues,and ileal contents were *** changes,serum levels of IL-1β,IL-6,IL-8,IL-10,IL-2.,TNF-α,and TGF-β,intestinal SIgA,and protein and mRNA expression of ZO-1,NF-κB,Occludin,MUC-2.Claudin-1,and IκB-αin colon tissues were *** effect of TCCL on the abundance and diversity of intestinal flora was analyzed using 16S rDNA *** TCCL treatment improved thymus and spleen weight,thymus and spleen indexes,and body weight,decreased tumor volumes and tumor tissue cell density,and alleviated injury to gastric,ileal,and colonic mucosal *** proteins and genes associated with inflammation,IL-10,TGF-β,SIgA,ZO-1,MUC-2.and Occludin were upregulated,whereas NF-κB,IL-1β,IL-6,TNF-α,IL-2.,IL-8,and IκB-αwere ***,TCCL increased the proportions of fecal Actinobacteria,AF12.Adlercreutzia,Clostridium,Coriobac

关键词： Chinese medicine Chemotherapy H2. hepatocellular carcinoma Intestinal barrier function Intestinal microecological balance

The In-Flight Realtime Trigger and Localization Software of GECAM

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Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： Xiao-Yun Zhao Shao-lin Xiong Xiang-Yang Wen Xin-Qiao li Ce Cai Shuo Xiao Qi Luo Wen-Xi {2. Dong-Ya Guo Zheng-Hua An Ke Gong Jin-Yuan liao Yan-Qiu Zhang Yue Huang Lu li Xing Wen fei Zhang Jing Duan Chen-Wei Wang Dong-li Shi {2. Zhang Qi-Bin Yi Chao-Yang li Yan-Bing Xu Xiao-Hua liang Ya-Qing liu Da-li Zhang Xi-Lei Sun Fan Zhang Gang Chen Huan-Yu Wang Sheng Yang Xiao-Jing liu Min Gao Mao-Shun li Jin-Zhou Wang Xing Zhou Yi Zhao Wang-Chen Xue Chao Zheng Jia-Cong liu Xing-Bo Han Jin-ling Qi Jia Huang Ke-Ke Zhang Can Chen Xiong-Tao Yang Dong-Jie Hou Yu-Sa Wang Rui Qiao Xiang Ma Xiao-Bo li Ping Wang Xin-Ying Song li-Ming Song Shi-Jie Zheng Bing li Hong-Mei Zhang Yue Zhu Wei Chen Jian-Jian He Zhen Zhang Jin Hou Hong-Jun Wang Yan-Chao Hao Xiang-Yu Wang Zong-Yuan Yang Zhi-Long Wen Zhi Chang Yuan-Yuan Du Rui Gao Xiao-fei Lan Yan-Guo li Gang li Xu-Fang li Fang-Jun Lu Hong Lu Bin Meng Feng Shi Hui Wang Hui-Zhen Wang Yu-{2. Xu Jia-Wei Yang Xue-Juan Yang Shuang-Nan Zhang Chao-Yue Zhang Cheng-Mo Zhang Zhi-Cheng Tang Cheng Cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space Science College China West Normal UniversityNanchong 637002China department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China Changchun University of Science and Technology Changchun 130022China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2.2. December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

基于量子蚁群算法的旅行商问题求解及算法评估

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大学物理 2024年第2期43卷 79-85页

作者：李炫秋黄斐君景鹏飞北京师范大学物理学系北京100875

量子蚁群算法是一种将量子理论与传统蚁群算法结合的高效生物进化算法,主要应用于故障诊断、路径规划、图像分割等问题的优化.基于传统蚁群算法的流程,介绍量子蚁群算法中的量子理论基础以及量子理论如何应用于蚁群算法.通过若干旅行商... 详细信息

量子蚁群算法是一种将量子理论与传统蚁群算法结合的高效生物进化算法,主要应用于故障诊断、路径规划、图像分割等问题的优化.基于传统蚁群算法的流程,介绍量子蚁群算法中的量子理论基础以及量子理论如何应用于蚁群算法.通过若干旅行商问题实例分析量子蚁群算法较传统蚁群算法的优势.针对目前研究多以离散指标来评估不同算法、难以直观显示不同算法综合差别的问题,提出一种综合评估算法搜索效率的方法,成功应用于量子蚁群算法和传统蚁群算法的对比,具有一定的实践意义.

关键词：量子蚁群算法蚁群算法旅行商问题算法评估

Nonchaoticity of Ordinary Differential Equations Describing Autonomous Transcriptional Regulatory Circuits

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Communications in Theoretical Physics 2008年第6期49卷 1639-1642页

作者： li peng-{2. HU Gang CHEN Run-Sheng department of Physics Beijing Normal University Beijing 100875 China beijing-Hong Kong-Singapore Joint Center of Nonlinear and Complex Systems Beijing Normal University Branch Beijing 100875 China Bioinformatics Laboratory Institute of Biophysics the Chinese Academy of Sciences Beijing 100101 China

Gene transcriptional regulation （TR） processes are often described by coupled nonlinear ordinary differential equations （ODEs）. When the dimension of TR circuits is high （e.g. n≥3） the motions of the corresponding ODEs may, very probably, show self-sustained oscillations and chaos. On the other hand, chaoticity may be harmful for the normal biological functions of TR processes. In this letter we numerically study the dynamics of 3-gene TR ODEs in great detail, and investigate many 4-, 5-, and lO-gene TR systems by randomly choosing figures and parameters in the conventionally accepted ranges. And we find that oscillations are very seldom and no chaotic motion is observed, even if the dimension of systems is sufficiently high （n≥3）. It is argued that the observation of nonchaoticity of these ODEs agrees with normal functions of actual TR processes.

关键词： transcriptional regulatory circuit periodic oscillation nonchaoticity

Ⅱ.~1S0 PAIRING CORRELATION IN SYMMETRIC NUCLEAR MATTER WITH DEBYE SCREENING EFFECTS

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Ⅱ.~1S0 PAIRING CORRELATION IN SYMMETRIC NUCLEAR MATTER WITH...

Ⅰ.IN-MEDIUM MESON EFFECTS ON THE EQUATION OF STATE OF HOT AND DENSE NUCLEAR MATTER

CCAST“研究禁闭与退禁闭相变的连续场论途径”研讨会

作者： Ji-sheng Chen peng-fei Zhuang Jia-rong {2. Institute of Particle Physics, Hua-Zhong normal University, Wuhan 430079, People''s Repub{2.c of china Physics department, Tsinghua University, beijing 100084,People''s Repub{2.c of china

＜正＞The So pairing of symmetric nuclear matter is discussed in the frame work of relativistic nuclear theory with Dyson-Schwinger equations（DSEs）. The in-medium nucleon and meson propagators are treated in a more self-consistent way through meson polarizations. The screening effects on mesons due to in-medium nucleon excitation are found to reduce the So pairing gap and shift remarkably the gap peak to low density region.

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Ⅰ.IN-MEDIUM MESON EFFECTS ON THE EQUATION OF STATE OF HOT A...

Searching for axion-like particles with the blazar observations of MAGIC and Fermi-LAT

CCAST“研究禁闭与退禁闭相变的连续场论途径”研讨会

作者： Ji-sheng Chen peng-fei Zhuang Jia-rong {2. Physics department, Tsinghua University, beijing 100084,People''s Repub{2.c of china Institute of Particle Physics, Hua-Zhong normal University, Wuhan 430079, People''s Repub{2.c of china

＜正＞The influence of the in-medium mesons on the effective nucleon mass and in turn on the equation of state of hot/dense nuclear matter is discussed in the Walecka model. Due to the self-consistent treatment of couplings between nucleons and a and ωmesons, the temperature and density dependence of the effective hadron masses approaches more towards the Brown-Rho scaling law, and the compression modulus K is reduced from 550 MeV in mean field theory to an accepted value 318.2.MeV.

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Chinese Physics C 2022年第8期46卷 262-272页

作者： Hai-Jun li Xiao-Jun Bi peng-{2. Yin Center for Advanced Quantum Studies Department of PhysicsBeijing Normal UniversityBeijing 100875China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China School of Physics University of Chinese Academy of SciencesBeijing 100049China

In this study,we explore the axion-like particle(ALP)-photon oscillation effect in the γ-ray spectra of the blazars Markarian 42.(Mrk 42.) and PG 1553+113,which are measured by the Major Atmospheric Gamma Imaging Cherenkov Telescopes(MAGIC) and Fermi Large Area Telescope(Fermi-LAT) with high *** Mrk42. and PG 1553+113 observations of 15 and five phases are used in the analysis,*** find that the combined analysis with all the 15 phases improves the limits of the Mrk 42. *** the selected blazar jet magnetic field and extragalactic background light models,the combined limit set by the Mrk 42. observations excludes the ALP parameter region with the ALP-photon coupling of g_(aγ)≥2.1.^(-11) GeV^(-1) for the ALP mass of~8×10^(-9)≤m_(a)≤2.1.^(-7) eV at 95% confidence *** main uncertainties of the analysis originate from the blazar jet magnetic field *** also find that the ALP hypothesis can slightly improve the fit to the PG1553+113 results in several parameter *** do not set the limit in this case.

关键词： axion γ-ray blazar

基于生理指标的儿童牙科恐惧与焦虑的评估模型

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基础医学与临床 2024年第5期44卷 705-708页

作者：张鹏张宇阳王非李西营国家儿童医学中心、首都医科大学附属北京儿童医院口腔科北京100045 清华大学社会科学学院心理学系北京100084 陕西师范大学现代教学技术教育部重点实验室陕西西安710119

目的探索口腔治疗场景下患者恐惧焦虑情绪所伴随的神经生理表征,并构建一种基于生理指标的儿童牙科恐惧与焦虑(DFA)的评估模型。方法纳入在北京儿童医院口腔科就诊的166例14周岁以下儿童。采用改良中文版儿童畏惧调查表-牙科分量表(CFSS... 详细信息

目的探索口腔治疗场景下患者恐惧焦虑情绪所伴随的神经生理表征,并构建一种基于生理指标的儿童牙科恐惧与焦虑(DFA)的评估模型。方法纳入在北京儿童医院口腔科就诊的166例14周岁以下儿童。采用改良中文版儿童畏惧调查表-牙科分量表(CFSS-DS)评定儿童DFA得分。使用腕式生理数据采集设备对儿童患者就诊期间的心率(HR)和皮肤电(GSR)进行全程连续测量。用重复测量方差分析对治疗前、中和后的生理数据进行差异检验;用皮尔逊(Pearson)相关分析对治疗前、中和后的生理数据与CFSS-DS分数做相关分析;建立最小绝对收缩和选择算法(LASSO)回归模型对儿童牙科恐惧与焦虑进行评估,用留一法(LOO)进行交叉验证。结果生理数据各维度在治疗前、中和后的变化差异显著(P<0.05);LASSO模型预测值与CFSS-DS原始分数之间皮尔逊相关系数r=0.30,P<0.05,说明本模型有较好的预测准确性。结论评估模型可以实现对儿童牙科恐惧与焦虑的客观、自动化的测量。

关键词：牙科恐惧与焦虑生理测量心率皮肤电反应