检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

从德语名词短语的分裂看德语语序的研究

解放军外国语学院学报 2008年第2期31卷 24-28页

作者：黎东良朱小安山东大学威海分校翻译学院山东威海264209 解放军外国语学院欧亚语系河南洛阳471003

德语语序的研究经历了3个发展阶段,即早期的非系统性单纯语法研究、句法与交际因素相结合的语言学研究和多学科相互渗透的系统化语序研究。德语名词短语分裂是一种特殊的语序:看似句法问题的名词短语的分裂实际上涉及到语义问题,语序的... 详细信息

德语语序的研究经历了3个发展阶段,即早期的非系统性单纯语法研究、句法与交际因素相结合的语言学研究和多学科相互渗透的系统化语序研究。德语名词短语分裂是一种特殊的语序:看似句法问题的名词短语的分裂实际上涉及到语义问题,语序的分裂影响到语义变化;语用因素也是促使语序改变的一个重要原因;语序的变化同时也是一种修辞手段;语序的研究不能只停留在句子层面上,而要在篇章层面上进行跨学科的深入研究。

关键词：德语语序名词短语分裂信息结构交际因素语义

在线全文

学校读者我要写书评

暂无评论

面粉加工企业危险废物贮存点建设与管理

粮油食品科技 2023年第6期31卷 131-137页

作者：李栋梁刘垚中粮粮谷控股有限公司北京100020

我国面粉加工企业从小而散逐步向集约化、规模化生产转变,过程中产生的危险废物种类和数量也随之增加。而面粉加工企业危险废物贮存管理基础相对薄弱,在危险废物贮存点的选址、建设及运行管理等方面亟待规范和加强。通过对面粉加工企业... 详细信息

我国面粉加工企业从小而散逐步向集约化、规模化生产转变,过程中产生的危险废物种类和数量也随之增加。而面粉加工企业危险废物贮存管理基础相对薄弱,在危险废物贮存点的选址、建设及运行管理等方面亟待规范和加强。通过对面粉加工企业危险废物种类进行分析,合理选定贮存场所类型。从建筑要求、包装容器、电气安全、物资配备、目视化标识五个维度分解细化了建设要素,提出针对性的安全环保措施,构建了面粉加工企业危险废物贮存点的建设模型。针对管理不规范的问题,从入库管理、贮存管理、出库管理三个环节提出了危险废物贮存环节的全流程合规性管理思路,为推动和指导面粉加工企业危险废物贮存点的规范化、标准化、系统化建设与管理提供参考。

关键词：面粉加工企业危险废物贮存点选址与建设管理

在线全文

学校读者我要写书评

暂无评论

黑河流域不同生育期生态用水量变化分析

干旱地区农业研究 2006年第1期24卷 164-168页

作者：张杰李栋梁中国气象局兰州干旱气象研究所甘肃省干旱气候变化与减灾重点实验室甘肃兰州730020 中国科学院寒区旱区环境与工程研究所甘肃兰州730000

根据不同农作物、森林等植被的生物学特性，采用张掖和额济纳旗的气象资料，估算了3～10月各旬平均的作物生态需水量，分析了张掖人工绿洲近20a来主要农作物的种植面积和灌溉面积、作物以及下游天然绿洲的生态需水量的生育期变化。结果... 详细信息

根据不同农作物、森林等植被的生物学特性，采用张掖和额济纳旗的气象资料，估算了3～10月各旬平均的作物生态需水量，分析了张掖人工绿洲近20a来主要农作物的种植面积和灌溉面积、作物以及下游天然绿洲的生态需水量的生育期变化。结果表明，绿洲产业结构调整的结果是，经济作物种植面积有所增加，粮食作物种植面积下降了26．6％。通过对黑河流域中游人工绿洲和下游天然绿洲逐旬生态需水量的估算发现，人工绿洲的主要粮食作物小麦、玉米与下游天然绿洲的生态需水量在生育期上不同步，小麦、玉米需水高峰分别在6月中旬和8月中旬，用水量分别为6．14mm／d和8．6mm／d；天然绿洲的需水高峰出现在8月下旬，为8mm／d。张掖人工绿洲的区域平均生态需水量高峰在6月中旬，为6．37mm／d，天然绿洲的需水高峰在8月下旬，区域最大需水量为6．06mm／d。对于整个流域，最大需水量高峰在6月中下旬，为6．03mm／d。中游人工绿洲与下游天然绿洲生态用水的时间差，为水资源的合理调配提供科学依据。

关键词：黑河流域生态需水量生育期人工绿洲天然绿洲

医用镁合金表面阳极氧化/茶多酚复合转化层耐腐蚀性能研究

在线全文

学校读者我要写书评

暂无评论

表面技术 2023年第1期52卷 196-205页

作者：李浩张皓申孝龙李栋梁杨成攀枝花学院钒钛学院四川攀枝花610000 攀枝花学院生物与化工学院四川攀枝花610000

目的在AZ31镁合金表面制备阳极氧化/茶多酚复合转化层,解决医用镁合金在植入环境中降解过快、易导致炎症等问题。方法使用阳极氧化法在镁合金表面构建阳极氧化(Anodization)层,之后在阳极氧化层上通过浸泡法制备多酚转化层,得到复合转化... 详细信息

目的在AZ31镁合金表面制备阳极氧化/茶多酚复合转化层,解决医用镁合金在植入环境中降解过快、易导致炎症等问题。方法使用阳极氧化法在镁合金表面构建阳极氧化(Anodization)层,之后在阳极氧化层上通过浸泡法制备多酚转化层,得到复合转化层,多酚选择表没食子儿茶素没食子酸酯(EGCG)。通过SEM、EDS、XRD、FTIR和XPS对转化层的表面形貌、成分结构进行分析,利用极化曲线、电化学阻抗谱、长期浸泡试验评价转化层的耐腐蚀行为。结果阳极氧化层内层致密,外层多孔,主要成分为MgO和MgSiO_(3)。在阳极氧化层表面构建EGCG转化层形成复合层后,外层孔洞被填补,且FTIR图谱中出现了EGCG的特征峰。电化学评价结果显示,与AZ31相比,复合转化层的自腐蚀电流密度降低了约2个数量级,高频容抗弧半径显著增大,等效电路模拟后所得极化电阻(R_(p))为179.425 kΩ·cm^(2),远大于裸材。长期浸泡试验结果显示,复合层可明显控制浸泡过程中溶液p H值的增加,且明显低于其他对照组。浸泡160 h后,表面腐蚀产物最少,具有良好的耐腐蚀性能。结论采用阳极氧化法和浸泡法在AZ31镁合金表面成功制备了阳极氧化/茶多酚复合层,明显提高了镁基底的耐蚀性能。选用的EGCG来源绿色、价格低廉,且具有抗氧化、抗炎等多重功效,为医用镁合金表面改性提供了一种新方案。

关键词：镁合金医用材料阳极氧化 EGCG 耐腐蚀能力

维普期刊数据库博看期刊

Epigenetic regulation of the inflammatory response in stroke

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3045-3062页

作者： Jingyi liang Fei Yang Zixiao li Qian li School of Basic Medical Sciences Capital Medical UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Laboratory for Clinical Medicine Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Beijing Key Laboratory of Cancer Invasion and Metastasis Research Capital Medical UniversityBeijingChina

Stroke is classified as ischemic or hemorrhagic,and there are few effective treatments for either *** mechanisms play a critical role in secondary brain injury following a stroke,which manifests as cytokine release,blood–brain barrier disruption,neuronal cell death,and ultimately behavioral *** the inflammatory response has been shown to mitigate this cascade of events in experimental stroke ***,in clinical trials of anti-inflammatory agents,longterm immunosuppression has not demonstrated significant clinical benefits for *** may be attributable to the dichotomous roles of inflammation in both tissue injury and repair,as well as the complex pathophysiologic inflammatory processes in *** acute harmful inflammatory responses or inducing a phenotypic shift from a pro-inflammatory to an anti-inflammatory state at specific time points after a stroke are alternative and promising therapeutic *** agents that can modulate inflammation requires a detailed understanding of the inflammatory processes of ***,epigenetic reprogramming plays a crucial role in modulating post-stroke inflammation and can potentially be exploited for stroke *** this review,we summarize current findings on the epigenetic regulation of the inflammatory response in stroke,focusing on key signaling pathways including nuclear factor-kappa B,Janus kinase/signal transducer and activator of transcription,and mitogen-activated protein kinase as well as inflammasome *** also discuss promising molecular targets for stroke *** evidence to date indicates that therapeutic targeting of the epigenetic regulation of inflammation can shift the balance from inflammation-induced tissue injury to repair following stroke,leading to improved post-stroke outcomes.

关键词： DNA methylation histone modification intracerebral hemorrhage ischemic stroke neuroinflammation neuroprotection non-coding RNA RNA methylation subarachnoid hemorrhage treatment

热带印度洋MJO对4—6月长江中下游地区降水的影响

在线全文

学校读者我要写书评

暂无评论

热带气象学报 2015年第5期31卷 691-699页

作者：魏恒汤绪梁萍李栋梁南京信息工程大学江苏南京210044 世界气象组织天气与减灾服务司上海市气候中心上海200030

利用站点降水资料、美国气候预测中心（CPC）的MJO指数和NCEP/DOE AMIP-II再分析资料,研究了热带印度洋MJO对4—6月长江中下游地区降水的影响及可能机制。（1）热带印度洋MJO对长江中下游地区降水有显著影响：热带印度洋MJO偏强（偏弱）... 详细信息

利用站点降水资料、美国气候预测中心（CPC）的MJO指数和NCEP/DOE AMIP-II再分析资料,研究了热带印度洋MJO对4—6月长江中下游地区降水的影响及可能机制。（1）热带印度洋MJO对长江中下游地区降水有显著影响：热带印度洋MJO偏强（偏弱）时,同期以及滞后1~2候时该地区降水偏多（偏少）。（2）热带印度洋MJO处在不同位相时,大尺度背景场有明显的差别：热带印度洋MJO偏强（偏弱）时,同期以及滞后1~2候时MJO活跃对流中心位于热带印度洋（西太平洋）,西太平洋副热带地区表现为反气旋性（气旋性）环流异常,孟加拉湾为气旋性（反气旋性）环流异常,长江中下游地区出现了异常上升（下沉）运动,水汽辐合增强（减弱）;伴随MJO的东传,水汽输送异常来源有所变化。（3）热带印度洋MJO通过激发Gill型响应和Rossby波列,对长江中下游地区降水产生影响。

关键词：气候学 MJO 统计分析降水长江中下游地区热带印度洋

FUBP3 mediates the amyloid-β-induced neuronal NLRP3 expression

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 2068-2083页

作者： Jing Yao Yuan li Xi liu Wenping liang Yu li liyong Wu Zhe Wang Weihong Song The National Clinical Research Center for Geriatric Disease Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Neurology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Pediatrics The Second Affiliated Hospital and Yuying Children’s HospitalKey Laboratory of Alzheimer’s Disease of Zhejiang ProvinceInstitute of AgingWenzhou Medical UniversityWenzhouZhejiang ProvinceChina Oujiang Laboratory(Zhejiang Laboratory for Regenerative Medicine Visionand Brain Health)WenzhouZhejiang ProvinceChina

Alzheimer's disease is characterized by deposition of amyloid-β,which forms extracellular neuritic plaques,and accumulation of hyperphosphorylated tau,which aggregates to form intraneuronal neurofibrillary tangles,in the *** NLRP3 inflammasome may play a role in the transition from amyloid-βdeposition to tau phosphorylation and *** NLRP3 is primarily found in brain microglia,and tau is predominantly located in neurons,it has been suggested that NLRP3 expressed by microglia indirectly triggers tau phosphorylation by upregulating the expression of pro-inflammatory ***,we found that neurons also express NLRP3 in vitro and in vivo,and that neuronal NLRP3 regulates tau *** biochemical methods,we mapped the minimal NLRP3 promoter and identified FUBP3 as a transcription factor regulating NLRP3 expression in *** primary neurons and the neuroblastoma cell line Neuro2A,FUBP3 is required for endogenous NLRP3 expression and tau phosphorylation only when amyloid-βis *** the brains of aged wild-type mice and a mouse model of Alzheimer's disease,FUBP3 expression was markedly increased in cortical *** analysis suggested that FUBP3 plays a role in neuron-mediated immune *** also found that FUBP3 trimmed the 5′end of DNA fragments that it bound,implying that FUBP3 functions in stress-induced *** findings suggest that neuronal NLRP3 may be more directly involved in the amyloid-β-to–phospho-tau transition than microglial NLRP3,and that amyloid-βfundamentally alters the regulatory mechanism of NLRP3 expression in *** that FUBP3 was only expressed at low levels in young wild-type mice and was strongly upregulated in the brains of aged mice and Alzheimer's disease mice,FUBP3 could be a safe therapeutic target for preventing Alzheimer's disease progression.

关键词： 5′end trimming Alzheimer's disease amyloid-beta amyloid-β-dependent transcription FUBP3 inflammasome inflammation neuron NLRP3 tau transcription factor

Morphological Mechanism and Experimental Verification of Self-healing of Basalt-fiber Modified Water-soaked Asphalt

在线全文

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 171-186页

作者： XIAO Minmin dong Jinyong li Chunyan GUO Xu REN Jianguo School of Urban Construction and Safety Engineering Shanghai Institute of TechnologyShanghai 201418China

This study investigates the mechanism of action of representative molecules of basalt fibers on the healing of water-soaked *** parameters,morphological characteristics,interfacial healing energy,and interfacial healing strength were analyzed using molecular dynamics and macroscopic tests under different time,temperature,and water conditions to evaluate the specific states and critical conditions involved in *** results indicate that basalt-fiber molecules can induce rearrangement and a combination of water-soaked asphalt at the healing *** groups with different bonding states increase the interfacial adsorption capacity of water-soaked *** interaction between basalt fiber molecules and water molecules leads to a"hoop"phenomenon,while aromatics-2 molecules exhibit a"ring band aggregation"*** former reduces the miscibility of water and asphalt molecules,while the latter causes slow diffusion of the ***,a micro-macro dual-scale comparison of interfacial healing strength was conducted at temperatures of 297.15 and 312.15 K to identify the strength transition point and critical temperature of 299.4 K during the self-healing process of basalt-fiber modified water-soaked asphalt.

关键词： water-soaked asphalt basalt-fibers self-healing properties moisture status molecular characterization

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

近50年兰州城乡气温变化特征及其周末效应

高原气象 2006年第6期25卷 1161-1167页

作者：李文莉李栋梁杨民兰州中心气象台甘肃兰州730020 中国科学院寒区旱区环境与工程研究所西部气候环境与灾害重点实验室甘肃兰州730000 甘肃省气象局甘肃兰州730020

利用兰州站和相邻的榆中站分别代表城市和乡村,采用其近50年逐日温度资料,应用周期分析方法,研究了两地气候变化特征及其周期性。结果表明:兰州年平均气温以0.34℃/10a显著升高,城市“热岛效应”显著,其变暖速率明显比临近乡村站快。规... 详细信息

利用兰州站和相邻的榆中站分别代表城市和乡村,采用其近50年逐日温度资料,应用周期分析方法,研究了两地气候变化特征及其周期性。结果表明:兰州年平均气温以0.34℃/10a显著升高,城市“热岛效应”显著,其变暖速率明显比临近乡村站快。规律性的工作日和双休日影响了城市气温变化,造成了明显的周末升温、7天周期的显著“周末效应”。

关键词：兰州市榆中城乡气温变化热岛效应周末效应