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有机氟工业 1972年第2期 1-21页

作者： N·b·levine

羧基亚硝基橡胶不仅表现出抗强氧化剂性和高压纯氧中的完全不燃性,还表现出良好的低温柔韧性和优良的抗溶剂性,因而具有极好的综合性能,适合于许多空间航行方面的用途.

关键词：机械性能涂料隔火硫化胶 TA 伸长率抗张强度力学性质力学性能扯断强度力学强度高分子溶液非牛顿流体聚合物溶液羧基取代基亚硝基橡胶弹性体

The Effects of Low Intensity Endurance Activity on Various Physiological Parameters and Exercise Induced Oxidative Stress in Dogs

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Open Journal of Veterinary Medicine 2014年第7期4卷 134-144页

作者： Janice L. Huntingford Corri b. levine Debbie J. Mustacich Devin Corrigan Robert L. Downey Joseph J. Wakshlag Annamaet Petfood Company Sellersville PA USA Department of Clinical Sciences Cornell University Ithaca NY USA Essex Animal Hospital Essex Canada Linus Pauling Institute Oregon State University Corvallis OR USA

The study of canine athlete physiology has focused on endurance sled dog racing and high intensity short duration Greyhound racing, yet the number of dogs competing in low intensity endurance activities is rising due to the increased numbers of hunting and companion dog activities. There is little information on the physiological effect of longer duration low intensity endurance activities. We set out to evaluate the serum biochemistry, oxidative stress, and cortisol response before and after two consecutive days of exercise in ten healthy unconditioned male dogs. Exercise sessions consisted of 120 minutes on an exercise wheel at 11 km/hour on 2 consecutive days. blood was collected at four time points: 24 hours pre-exercise (sample 1, Day 0, resting);2 min post-exercise on days 1 and 2, (samples 2 and 3, respectively);and 20 hours post-exercise, collected on day 3(sample 4). Hematocrit, blood gases, serum chemistry, uric acid, cortisol, and F2-isoprostanes were determined. Serum biochemistry and hematocrit suggested hemoconcentration, mild muscle damage and respiratory alkalosis during exercise, which was expected in the unconditioned canine athlete. In addition, plasma indices of oxidative damage (F2-isoprostanes) increased, as did plasma uric acid (an endogenous antioxidant). Importantly, similar to human studies, plasma F2-isoprostanes decreased 24 hours after exercise suggesting a protective effect of exercise. Serum cortisol concentrations were also markedly elevated at the end of exercise on both days suggesting that timing of sampling may play a role in interpreting cortisol results when looking at previous field studies.

关键词： Exercise Cortisol Isoprostane Dehydration Uric Acid

The Effects of Exercise on Serum Chemistry, Non-Esterified Fatty Acid, Insulin and Glucagon Dynamics during a 400 Meter Sprint in Racing Greyhounds

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Open Journal of Veterinary Medicine 2015年第6期5卷 142-151页

作者： Michael J. bell Emily M. Donaldson Sabine Mann Robert L. Gillette Corri b. levine Joseph J. Wakshlag Craigieburn Animal Hospital 9 Craigieburn Rd. Craigieburn Australia Cornell University College of Veterinary Medicine Department of Clinical Sciences Ithaca NY USA Cornell University College of Veterinary Medicine Department of Population Medicine Ithaca NY USA Red bank Referral Center Sports Medicine and Rehabilitation Service Red Bank NJ USA

The effects of Greyhound racing on plasma insulin, glucagon and non-esterified fatty acid have not been extensively studied. We sought to examine the effects of exercise in 19 greyhounds trialed over 400 meters on serum biochemistry, osmolality, nonessential fatty acids, and the major glucoregulatory hormones insulin and glucagon, before and after racing. Due to the non-traditional dietary patterns of many racing Greyhounds, the diet was analyzed for macro and micro-nutrient assessment to determine adequacy of the diet. Many significant biochemical changes were observed and agreed with previous studies, except for low resting glucose, low post-exercise globulin and phosphorus concentrations, and a high CK both before and after exercise. Insulin concentrations increased 10 minutes post-exercise which might be a result of the rise in serum glucose observed. Non-esterified fatty acids decreased 10 minutes post-exercise, as a likely result of the insulin facilitated cellular uptake of fatty acids early in recovery. Glucagon concentrations did not change after exercise despite the rise in insulin. The diet analysis found some mineral deficiencies in sodium, selenium, iodine and copper;and contained a far higher protein and fat content, being atypical of diets that have been shown to improve the performance in racing Greyhounds.

关键词： Greyhound Insulin Glucagon Non-Esterified Fatty Acid Glucose

用皮试法检查青霉素过敏青霉噻唑类化合物的制备和结构分析

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国外医药(抗生素分册) 1984年第4期 340-343页

作者： bernard M.Goldschmidt ,bernard b.levine ,宗秀华

如何可靠地预测青霉素的过敏反应是一个有理论性和临床实用性的问题。以往本室和其它实验室曾研究用适当的试剂做皮内试验。我们曾用过:1)青霉噻唑—聚赖氨酸和2)用微量的一种混合物包括有青霉素及其水解产物:青霉噻唑酸、青霉噻唑酰胺... 详细信息

如何可靠地预测青霉素的过敏反应是一个有理论性和临床实用性的问题。以往本室和其它实验室曾研究用适当的试剂做皮内试验。我们曾用过:1)青霉噻唑—聚赖氨酸和2)用微量的一种混合物包括有青霉素及其水解产物:青霉噻唑酸、青霉噻唑酰胺和青霉酸。近来设计了一种改良的皮试剂,受到美国国立过敏和感染病研究所(NIAID)的推崇,为多所临床中心采用。这新的试剂是

关键词：青霉素化学位移抗菌素谱线位移化合物内酞胺

Caloric restriction mimetics enhance anticancer immunosurveillance

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Caloric restriction mimetics enhance anticancer immunosurvei...

Logitech PageScan USb——最方便的扫描产品

第十一届全国免疫学学术大会

作者： Pol J Pietrocola F Vacchelli E Rao S Enot DP baracco EE Levesque S Castoldi F Jacquelot N Yamazaki T Senovilla L Marino G Aranda F Durand S Sica V Chery A Lachkar S Sigl V bloy N buque A Falzoni S Ryffel b Apetoh L Di Virgilio F Madeo F Maiuri MC Zitvogel L levine b Penninger JM Kroemer G

Caloric restriction mimetics(CRMs)are compounds that mimic the biochemical effects of nutrient deprivation by reducing lysine acetylation of cellular proteins,thus triggering *** CRMs have been identified including hy...

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电子与电脑 1998年第1期 43-43页

作者： Daniel b.levine ,唐宏

在打开Logitech公司售价229美元的PageScan USb的产品包装时,我们注意到的第一件事就是该产品的附件很少:没有电源模块、没有并行旁通式连接件,没有SCSI卡或电缆。产品包中只有一个3.5英寸高的馈纸式扫描仪、一条USb电缆以及一片包含Ad... 详细信息

在打开Logitech公司售价229美元的PageScan USb的产品包装时,我们注意到的第一件事就是该产品的附件很少:没有电源模块、没有并行旁通式连接件,没有SCSI卡或电缆。产品包中只有一个3.5英寸高的馈纸式扫描仪、一条USb电缆以及一片包含Adobe公司PhotoDeluxe和用于OCR的Xerox Textbridge等软件的CD-ROM盘。将参测的beta版PageScan USb配置的那条独立电缆插入我们的CyberMax Cyrix测试系统的USb端口后,测试系统中配置的Win 95操作系统便识别出该扫描仪,并提示我们插入驱动程序盘(连接该扫描仪的Win 95系统应该是OSR2版本并有USb补充支持)。大约30秒钟后,按下该扫描仪侧面上的按钮就可开始扫描各种材料,如:

关键词： Logitech PageScan USb 电缆软件扫描仪传感器

Corel Lumiere向Premiere提出挑战

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电子与电脑 1997年第6期4卷 41-41页

作者： Daniel b.levine 丁江峰

那些初露头脚的导演们终于可以实现他们的梦想了,他们都希望有“侏罗纪公园”那样宏大的场面和“杀手托马托斯的攻击”那样的预算。在价值99美元的软件包Lumiere Suite中,Corel把其新的非线性数字视频编辑程序Lumiere与三维透视以及图... 详细信息

那些初露头脚的导演们终于可以实现他们的梦想了,他们都希望有“侏罗纪公园”那样宏大的场面和“杀手托马托斯的攻击”那样的预算。在价值99美元的软件包Lumiere Suite中,Corel把其新的非线性数字视频编辑程序Lumiere与三维透视以及图像编辑软件包CorelMotion 3D和CorelPhoto-Paint 6组合在一起。我们对Lumiere的β版本进行了测试。

关键词： CorelLumiere Premiere 应用软件视频编辑器

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Qualcomm Eudora Pro 3.0——第一流的Internet E-mail

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电子与电脑 1997年第2期4卷 20-20页

作者： Daniel b.levine 高亚林

很难想象没有e-mail的生活是什么样子。如果你是经商的,则很可能已经有了一套安装好的e-mail系统,尤其是如果你使用Windows 95或Windows NTWorkstation和MicrosoftExchange的话。

关键词： Internet E-mail EudoraPro3.0

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Subchronic Oral Toxicity of Pyridostigmine bromide in Rats

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biomedical and Environmental Sciences 1991年第3期4卷 283-289页

作者： b.S.levine R.LONG H.CHUNG Department of Pharmacology University of Illinois at Chicago Chicago IL 60680Pathology Associates Inc. Chicago IL 60616Walter Reed Army Institute of Research WashingtonDC 20307

This study evaluated the oral toxicity of pyridostigmine bromide in Sprague-Dawley rats when administered for 13 weeks by daily gavage. Groups of 10 rats/sex received doses of 0, 5, 15, 30, or 60 mg/kg/day. Toxicity was limited to exaggerated cholinergic stimulation at doses of 15 mg/kg/day or greater. Significant findings included tremors and inhibition of RbC acetylcholinesterase. Thus, 5 mg/kg/day of pyridostigmine bromide appears to be the no observed toxic effect level under the conditions of the present investigation.

关键词： Subchronic Oral Toxicity of Pyridostigmine bromide in Rats

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T cells from induced and spontaneous models of SLE recognize a common T cell epitope on β2-glycoprotein Ⅰ

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Cellular & Molecular Immunology 2019年第8期16卷 685-693页

作者： David Salem Rebecca Subang Masataka Kuwana Jerrold S.levine Joyce Rauch Division of Rheumatology Department of MedicineResearch Institute of the McGill University Health CentreMontrealQCCanada Department of Allergy and Rheumatology Nippon Medical SchoolGraduate School of MedicineTokyoJapan Section of Nephrology Department of MedicineUniversity of Illinois at ChicagoChicagoILUSA Section of Nephrology Department of MedicineJesse Brown Veterans Affairs Medical CenterChicago IL USA

Systemic lupus erythematosus is a prototypic model for b-cell epitope spread in *** to numerous molecularly distinct self-antigens emerge in a sequential manner over several years,leading to disease *** the earliest autoantibodies to appear are those targeting phospholipid-binding proteins,particularlyβ2-glycoprotein Ⅰ.Notably,mice immunized with β2-glycoprotein Ⅰ and lipopolysaccharide develop a strong T cell response to β2-glycoprotein Ⅰ that is associated with autoantibody production and renal disease,similar to that seen in human *** we hypothesized that mice with murine systemic lupus erythematosus,whether induced or spontaneous,should have T cells that recognizeβ2-glycoprotein *** evaluated the response of splenic T cells from mice with induced(C57bL/6 and C3H/HeN)and spontaneous(MRL/lpr)systemic lupus erythematosus to peptides spanning the entire sequence of humanβ*** found that mice with induced and spontaneous systemic lupus erythematosus recognize a common T cell epitope(peptide 31;LYRDTAVFECLPQHAMFG)in domain Ⅲ ofβ2-glycoprotein I.β2GPI-reactive CD4^(+)T cells from the two models differed primarily in cytokine production:T cells from mice with induced SLE expressed IFN-γ,while T cells from MRL/lpr mice expressed both IL-17 and IFN-γ,indicating that IL-17-expressing T cells are not necessary for generating aβ2GPI-reactive T cell *** data suggest that the generation of aβ2-glycoprotein Ireactive T cell response is shared by both induced and spontaneous models of systemic lupus erythematosus and that this T cell response may mediate epitope spread to autoantibodies in both models.

关键词： β2-glycoprotein I T cells systemic lupus erythematosus autoantibodies MHC class II haplotypes