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Chinese Journal of Catalysis 2022年第5期43卷 1238-1246页

作者： Zixun Yu Chang Liu Yeyu Deng Mohan Li Fangxin She leo Lai Yuan Chen Li Wei School of Chemical and Biomolecular Engineering The University of SydneyDarlingtonNew South WalesAustralia

Efficient and selective oxygen reduction reaction(ORR)electrocatalysts are critical to realizing decentralized h_(2)O_(2)production and *** we demonstrate a facile interfacial engineering strategy using a hydrophobic ionic liquid(IL,i.e.,[BMIM][NTF2])to boost the performance of a nitrogen coordinated single atom cobalt catalyst(i.e.),cobalt phthalocyanine(CoPc)supported on carbon nanotubes(CNTs).We find a strong correlation between the ORR performance of CoPc/CNT and the thickness of its IL *** characterization revealed that a higher O_(2)solubility(2.12×10^(−3)mol/L)in the IL compared to aqueous electrolytes provides a local O2 enriched surface layer near active catalytic sites,enhancing the ORR ***,the hydrophobic IL can efficiently repel the as‐synthesized h_(2)O_(2)molecules from the catalyst surface,preventing their fast decomposition to h_(2)O,resulting in improved h_(2)O_(2)*** to CoPc/CNT without IL coatings,the catalyst with an optimal~8 nm IL coating can deliver a nearly 4 times higher mass specific kinetic current density and 12.5%higher h2O2 selectivity up to 92%.In a two‐electrode electrolyzer test,the optimal catalyst exhibits an enhanced productivity of 3.71 molh2O2 gcat^(–1)h^(–1),and robust *** IL‐based interfacial engineering strategy may also be extended to many other electrochemical reactions by carefully tailoring the thickness and hydrophobicity of IL coatings.

关键词： hydrogen peroxide Ionic liquid Oxygen reduction reaction Single‐atom catalyst heterogeneous molecular catalyst

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Test of the Rosetta Pedotransfer Function for Saturated hydraulic Conductivity

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Open Journal of Soil Science 2012年第3期2卷 203-212页

作者： Carlos Alvarez-Acosta Robert J. Lascano leo Stroosnijder Cropping System Research Laboratory Wind Erosion and Water Conservation Research Unit 3810 4th St Lubbock TX 79415 USA Wageningen University Land Degradation and Development Group Soil Science Centre P. O. Box 47 6700 AA Wageningen The Netherlands

Simulation models are tools that can be used to explore, for example, effects of cultural practices on soil erosion and irrigation on crop yield. however, often these models require many soil related input data of which the saturated hydraulic conductivity (Ks) is one of the most important ones. These data are usually not available and experimental determination is both expensive and time consuming. Therefore, pedotransfer functions are often used, which make use of simple and often readily available soil information to calculate required input values for models, such as soil hydraulic values. Our objective was to test the Rosetta pedotransfer function to calculate Ks. Research was conducted in a 64-ha field near Lamesa, Texas, USA. Field measurements of soil texture and bulk density, and laboratory measurements of soil water retention at field capacity (–33 kPa) and permanent wilting point (–1500 kPa), were taken to implement Rosetta. Calculated values of Ks were then compared to measured Ks on undisturbed soil samples. Results showed that Rosetta could be used to obtain values of Ks for a field with different textures. The Root Mean Square Difference (RMSD) of Ks at 0.15 m soil depth was 7.81 × 10–7 m·s–1. Further, for a given soil texture the variability, from 2.30 × 10–7 to 2.66 × 10–6 m·s-1, of measured Ks was larger than the corresponding RMSD. We conclude that Rosetta is a tool that can be used to calculate Ks in the absence of measured values, for this particular soil. Level h5 of Rosetta yielded the best results when using the measured input data and thus calculated values of Ks can be used as input in simulation models.

关键词： Rosetta Saturated hydraulic Conductivity Ks Pedotransfer Function

ThE PAThOLOGY AND TREATMENT OF JOINT SPRAIN

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中华医学杂志(英文版) 1935年第6期49卷 521-528页

作者： leo J.MILTNER h.C.FANG From the Division of Orthopedic Surgery Department of Surgery and the Department of PathologyPeiping Union Medical CollegePeipingChina

The term sprain signifies an injury of the soft tissues within oraround a joint when the movements of that joint are carried beyondtheir normal physiological limits,or when the bones entering into theformation of the joint are deflected in some abnormal plane,withoutactual *** conditions such as previous injury or mal-alignment due to congenital or acquired causes(i.e.,congenital clubfoot,rachitic knock knee,etc.),predispose to *** lesions which occur during sprain vary consider-

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h pylori status and angiogenesis factors in human gastric carcinoma

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World Journal of Gastroenterology 2006年第34期12卷 5465-5472页

作者： Anita Mangia Annalisa Chiriatti Girolamo Ranieri Ines Abbate Maria Coviello Giovanni Simone Francesco Alfredo Zito Severino Montemurro Antonello Rucci Alfredo Di leo Stefania Tommasi Pasquale Berloco Jian Ming Xu Angelo Paradiso Clinical Experimental Oncology Laboratory National Cancer Institute 70126 Bari Italy Interventional Radiology Unit National Cancer Institute 70126 Bari Italy Chemical-Clinical-Microbiology and Immunology Laboratory Unit National Cancer Institute70126 Bari Italy histopathology Unit National Cancer Institute 70126 Bari Italy Gastroenterology Surgical Unit National Cancer Institute Bari Italy Department of Emergency and Organ Transplantation Section of Gastroenterology University of Bari Italy Laboratory of Biochemistry IRCCS 'Saverio de Bellis' Castellana Grotte (BA) Italy Department of Gastrointestinal Cancer Beijing 307 Hospital Cancer Center Beijing China

AIM： To investigate h pylori expression in gastric cancer patients in relation to primary tumor angiogenic markers, such as microvessel density （MVD）, thymidine phosphorylase （TP）, vascular endothelial growth factor receptor-1 （VEGF-R1）, p53 and circulating VEGF levels. METhODS： Angiogenic markers were analyzed immunohistochemically in 56 primary gastric cancers. h pylori cytotoxin （vacA） and the cytotoxin-associated gene （cagA） amplification were evaluated using PCR assay. Serum h pylori IgG antibodies and serum/plasma circulating VEGF levels were detected in 39 and 38 patients by ELISA, respectively. RESULTS： A total of 69% of patients were positive for circulating IgG antibodies against hpylori. cagA-positive h pylor/strains were found in 41% of gastric patients. vacA was found in 50% of patients; s1 strains were more highly expressed among vacA-positive patients. The presence of the s1 strain was significantly associated with cagA （P = 0.0001）. MVD was significantly correlated with both tumor VEGF expression （r = 0.361, P = 0.009） and serum VEGF levels （r = -0.347, P = 0.041）.Conversely, neither VEGF-R1 expression nor MVD was related to p53 expression. however, h pylori was not related to any angiogenic markers except for the plasma VEGF level （P = 0.026）. CONCLUSION： h pylori antigen is related to higher plasma VEGF levels, but not to angiogenic characteristics. It can be hypothesized that the toxic effects of h pylori on angiogenesis occurs in early preclinical disease phase or in long-lasting aggressive infections, but only when high h pylori IgG levels are persistent.

关键词： h pylori Gastric carcinoma Angiogenesis

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二酪氨酸层赋予酵母孢子抗氧化活性

食品与生物技术学报 2019年第10期38卷 119-125页

作者： MUKAMA Omar leo Bemena 王晓文高晓冬中西秀树江南大学生物工程学院

酿酒酵母(Saccharomyces cerevisiae)孢子壁是一个多层结构,其最外层为二酪氨酸层,由酚类化合物NN′-二甲酰基二酪氨酸组成。二酪氨酸层是酵母孢子壁独有的结构,在酵母营养细胞的细胞壁中不存在。因为许多细胞酚类化合物能够清除自由基... 详细信息

酿酒酵母(Saccharomyces cerevisiae)孢子壁是一个多层结构,其最外层为二酪氨酸层,由酚类化合物NN′-二甲酰基二酪氨酸组成。二酪氨酸层是酵母孢子壁独有的结构,在酵母营养细胞的细胞壁中不存在。因为许多细胞酚类化合物能够清除自由基,我们猜测NN′-二甲酰基二酪氨酸可以作为一种抗氧化剂。为了研究孢子的抗氧化性,将营养细胞、野生型孢子和dit1?驻孢子培养在强氧化剂h2O2中,观察现象。本研究发现相对于酵母营养细胞,含有二酪氨酸层的野生型孢子具有抗自由基的能力使孢子具有抗氧化活性,同时二酪氨酸层缺陷型菌株dit1?驻孢子对自由基敏感。另外,本研究发现NN′-二甲酰基二酪氨酸能够清除自由基。因此,NN′-二甲酰基二酪氨酸可在未来用作一种新型的抗氧化材料。

关键词：酿酒酵母孢子二酪氨酸层 NN′-二甲酰基二酪氨酸抗氧化

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NOTE ON ThE OCCURRENCE AND SIGNIFICANCE OF DEFICIENCY OF ThE SEPTUM PELLUCIDUM

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中华医学杂志(英文版) 1934年第2期048卷 138-141页

作者： leo ALEXANDER T. h. SUh Division of Neurology Peiping Union Medical College Peiping China M.D.

Deficiency of the septum pellucidum has been reported by a number of observers. Ernst (1909) describes absence of the septum pellucidum in different cases of arhinencephaly and aplasia of the corpus callosum, and thinning and sieve-like perforation of the septum in hydrocephalus. Dandy and Blackfan (1914) found the septum pellucidum already absent a month after operation in all their cases of hydrocephalus produced experimentally in young dogs between 2 and 6 months of age. In his alticle on the treatment of hydrocephalus Dandy (1921) gives a figure

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New fecal test for non-invasive helicobacter pylori detection:A diagnostic accuracy study

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World Journal of Gastroenterology 2018年第27期24卷 3021-3029页

作者： Andrea Iannone Floriana Giorgio Francesco Russo Giuseppe Riezzo Bruna Girardi Maria Pricci Suetonia C Palmer Michele Barone Mariabeatrice Principi Giovanni FM Strippoli Alfredo Di leo Enzo Ierardi Section of Gastroenterology Department of Emergency and Organ TransplantationUniversity of BariBari 70124Italy Department of Emergency and Organ Transplantation University of BariBari 70124Italy ThD SpA Correggio(Reggio Emilia)42015Italy National Institute of Gastroenterology “S De Bellis”Research HospitalCastellanaGrotte(Bari)70013Italy Department of Medicine University of Otago ChristchurchChristchurch 8011New Zealand Diaverum Academy Lund 22229Sweden Diaverum Medical Scientific Office Lund 22229Sweden Sydney School of Public health University of SydneySydney NSW-2000Australia Section of Nephrology Department of Emergency and Organ TransplantationUniversity of BariBari 70124Italy

AIM To assess the diagnostic accuracy of a new fecal test for detecting helicobacter pylori(h. pylori), using ^(13)Curea breath test as the reference standard, and explore bacterial antibiotic resistance. METhODS We conducted a prospective two-center diagnostic test accuracy study. We enrolled consecutive people≥ 18 years without previous diagnosis of h. pylori infection, referred for dyspepsia between February and October 2017. At enrollment, all participants underwent 13 C-urea breath test. Participants aged over 50 years were scheduled to undergo upper endoscopy with histology. Participants collected stool samples 1-3 d after enrollment for a new fecal investigation(ThD fecal test). The detection of bacterial 23 S rRNA subunit gene indicated h. pylori infection. We also used the index diagnostic test to examine mutations conferring resistance to clarithromycin and levofloxacin. Independent investigators analyzed index test and reference test standard results blinded to the other test findings. We estimated sensitivity, specificity, positive(PPV) and negative(NPV) predictive value, diagnostic accuracy, positive and negative likelihood ratio(LR), together with 95% confidence intervals(CI).RESULTS We enrolled 294 consecutive participants(age: Median 37.0 years, IQR: 29.0-46.0 years; men: 39.8%). Ninetyfive(32.3%) participants had a positive ^(13)C-urea breath test. Twenty-three(7.8%) participants underwent upper endoscopy with histology, with a full concordance between ^(13)C-urea breath test and histology in detecting h. pylori infection. Four(1.4%) out of the 294 participants withdrew from the study after the enrollment visit and did not undergo ThD fecal testing. In the 290 participants who completed the study, the ThD fecal test sensitivity was 90.2%(CI: 84.2%-96.3%), specificity 98.5%(CI:96.8%-100%), PPV 96.5%(CI: 92.6%-100%), NPV 95.6%(CI: 92.8%-98.4%), accuracy 95.9%(CI: 93.6%-98.2%), positive LR 59.5(CI: 19.3-183.4), negative LR 0.10(CI: 0.05-0.18). Out of 8

关键词： helicobacter pylori Fecal test Feces Stools 23S rRNA Molecular analysis Antibiotic resistance Diagnostic accuracy

B200和B5000计算机系统所采用的相互连接技术

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计算机工程与应用 1965年第7期 2-8页

作者： leo E.Thomas ,Kenneth h. ,李意天

本文阐述B200和B5000电子数据处理系统是如何通过取消所有的人工布线而降低相互连接的成本和提高可靠性的。 B200系统(图1)是介于中小型的商用计算机,它特别适用于处理银行及商业问题。B200系统的单价介于75,000～500,000美元,

关键词：电子数据处理触点 B200 B5000 接地板黝黝电路插件跨接插座电气装置件电路板线路板中央处理机

how antibiotic resistances could change helicobacter pylori treatment:A matter of geography?

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World Journal of Gastroenterology 2013年第45期19卷 8168-8180页

作者： Enzo Ierardi Floriana Giorgio Giuseppe Losurdo Alfredo Di leo Mariabeatrice Principi Division of Gastroenterology Department of Emergency and Organ Transplantation 70124 Bari Italy

Therapeutic management of helicobacter pylori(***)remains an unsolved ***,no therapeutic regimen is able to cure the infection in all treated patients,and in many the infection persists despite the administration of several consecutive standard *** antibiotic resistance reports describe alarming results,the outcome of therapeutic regimens does not seem to parallel this scenario in most cases,since a successful performance is often reached in more than 80%of ***,the phenomenon of increasing antibiotic resistance is being closely studied,and the results show controversial aspects even in the same geographic *** the continents of Europe,America,Asia,Africa,and Oceania,minimal and maximal values of resistance to the main antibiotics(clarithromycin,amoxicillin,metronidazole,and levofloxacin)feature wide ranges in different *** real enigma is therefore linked to the several different therapeutic regimens,which show results that often do not parallel the in vitro findings even in the same areas.A first aspect to be emphasized is that some regimens are limited by their use in very small geographic ***,not all therapeutic trials have considered bacterial and host factors affecting the therapeutic *** additional use of probiotics may help to reduce adverse events,but their therapeutic impact is *** conclusion,the"ideal therapy",paradoxically,appears to be a"utopia",despite the unprecedented volume of studies in the field and the real breakthrough in medical practice made by the discovery and treatment of *** ample discrepancies observed in the different areas do not encourage the development of therapeutic guidelines that could be valid *** these bases,one of the main challenges for the future might be identifying a successful solution to overcome antibiotic *** this context,geography must be considered a relevant matter.

关键词： helicobacter pylori Antibiotic resistance Geography Therapeutic regimens Therapeutic outcome

B200及B5000计算机系统中的连接技术

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计算机研究与发展 1965年第11期 12-16+40页

作者： leo E.Thomas Kenneth h.White 陈立忠

本文论述在B200和B5000型电子数据处理系统中如何通过取消全部手工接线来降低连接成本和增加连接可靠性的问题。 B200系统(图1)为介于小型与中型之间的商用计算机,适用于银行和商业方面。B5000系统(图2)为用于商业和科学方面的中型至大... 详细信息

本文论述在B200和B5000型电子数据处理系统中如何通过取消全部手工接线来降低连接成本和增加连接可靠性的问题。 B200系统(图1)为介于小型与中型之间的商用计算机,适用于银行和商业方面。B5000系统(图2)为用于商业和科学方面的中型至大型范围的高速计算机。本文将以B5000系统为例,来说明解决相互连接问题的一些方法。尽管B5000系统比B200系统大得多,而且快得多,但是在两个系统中都采用了相同的插件和连接方式。 B200和B5000型电子数据处理系统的设计原则包括: 1.插头座、插件、底板接线

关键词：插头座跨接插座接点连接器电气装置件 B5000 B200 磁性圆盘存储器磁盘存储器底板插针电子数据处理