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LIVESTOCK AND POULTRY MANURE MANAGEMENT FROM THE PERSPECTIVE OF CARBON NEUTRALITY IN CHINA

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Frontiers of Agricultural Science and Engineering 2023年第3期10卷 341-362页

作者： leli zhang Reaihan E Mahmoud MALI Hongjian LIN Shuai zhang Shuqin JIN Zhiping ZHU Jianjun HU Yiqing YAO Yong SUN Shuiping YAN Zhidan LIU Laboratory of Environment-Enhancing Energy(E2E) College of Water Resources and Civil EngineeringChina Agricultural UniversityBeijing 100083China Key Laboratory of Agricultural Engineering in Structure and Environment Ministry of Agriculture and Rural AffairsBeijing 100083China Agricultural Engineering Research Institute Agricultural Research CenterGiza 12311Egypt College of Biosystems Engineering and Food Science Zhejiang UniversityHangzhou 310058China College of Animal Science and Technology China Agricultural UniversityBeijing 100193China Research Center for Rural Economy Ministry of Agriculture and Rural AffairsBeijing 100810China Institute of Environmental and Sustainable Development in Agriculture Chinese Academy of Agriculture SciencesBeijing 100081China College of Mechanical&Electrical Engineering Henan Agricultural UniversityZhengzhou 450002China College of Mechanical and Electrical Engineering Northwest A&F UniversityYangling 712100China College of Engineering Northeast Agricultural UniversityHarbin 150030China College of Engineering Huazhong Agricultural UniversityWuhan 430070China

The rapid growth of the livestock and poultry production in China has led to a rise in manure generation,which contributes to the emissions of GHGs(greenhouse gases including CH_(4),N_(2)O and CO_(2))and other harmful gases(NH_(3),H_(2)S).Reducing and managing carbon emissions has become a critical global environmental imperative due to the adverse impacts of *** previous reviews that focused on resource recovery,this work provides an unique insight of transformation from resource-oriented manure treatment to integration of resource recovery with pollution reduction,carbon accounting and trading,focusing on the sustainable development of manure management *** the importance of accounting methodologies for carbon emission and trading system toward carbon neutrality society,suggestions and strategies including attaching high importance to the development of more accuracy accounting methodologies and more practical GHG emission reduction methodologies are given in this *** work directs the establishment of carbon reduction methodologies and the formulation of governmental policies for livestock and poultry manure management system in China.

关键词： valorization of animal manure manure management carbon emission carbon footprint methodology carbon trading

1例肾病综合征患儿他克莫司相关可逆性后部脑病综合征的药学监护

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医药导报 2024年第2期43卷 292-298页

作者：唐乐丽黄怡蝶张迅捷朱琳李智平国家儿童医学中心复旦大学附属儿科医院临床药学部上海201102 广东省珠海市妇幼保健院药学部珠海519000

目的介绍1例他克莫司治疗中发生可逆性后部脑病综合征(PRES)的肾病综合征患儿的药学监护,为相关疾病的治疗和药学服务积累经验。方法临床药师对患儿服用他克莫司引起药物性PRES的关联性进行分析评价,同时参考循证证据提出优化药物治疗建... 详细信息

目的介绍1例他克莫司治疗中发生可逆性后部脑病综合征(PRES)的肾病综合征患儿的药学监护,为相关疾病的治疗和药学服务积累经验。方法临床药师对患儿服用他克莫司引起药物性PRES的关联性进行分析评价,同时参考循证证据提出优化药物治疗建议,提供个体化药物服务。结果经过止痉、控制血压、降颅压、他克莫司减量等治疗,患儿临床症状好转,复查头颅磁共振成像(MRI)提示脑内异常信号部分吸收,病灶较前明显缩小。结论对于他克莫司相关PRES,临床药师可在降压药物选择、基于血药浓度监测的治疗方案调整、施行针对性的药学监护与教育等方面,提高患者长期用药的安全性和有效性。

关键词：他克莫司肾病综合征可逆性后部脑病综合征药学服务

The biological functions and metabolic pathways of valine in swine

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长江中下游地区流域生态资产价值评估——以新安江流域为例

Journal of Animal Science and Biotechnology 2024年第1期

作者： Chuni Wang Yao Peng Yiru zhang Juan Xu Sheng Jiang leli Wang Yulong Yin

来源：博看期刊评论

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中国地质 2024年第4期51卷 1252-1265页

作者：宗乐丽陈孜张明陈宗芳牛晓楠唐志敏周墨张洁王尚晓田福金张晓东黄丁伶中国地质调查局南京地质调查中心江苏南京210016 中国人民解放军陆军工程大学江苏南京210007

【研究目的】生态资产评估有助于理清区域生态资源本底,为建立健全自然资源监管技术体系,实施生态补偿政策提供科学依据,对于推动生态产品价值实现具有重要意义。【研究方法】本文构建了生态资产价值评估的方法指标体系,通过集成土地利... 详细信息

【研究目的】生态资产评估有助于理清区域生态资源本底,为建立健全自然资源监管技术体系,实施生态补偿政策提供科学依据,对于推动生态产品价值实现具有重要意义。【研究方法】本文构建了生态资产价值评估的方法指标体系,通过集成土地利用、遥感影像、气象、地球化学以及社会经济等多源数据,开展生态资产存量、生态资产质量以及生态资产价值评估,并结合地理探测器探求生态系统服务价值的空间分异影响因素。【研究结果】2020年新安江流域生态资产质量等级以良、中为主,分别占比80.96%、10.25%;生态资产存量综合指数为0.77,湿地、森林与园地占主要位置;流域生态系统服务价值为1334.48亿元,森林资源与水资源价值占比最高,坡度、高程和年降水量为影响生态系统服务价值空间分异的主要驱动因子。【结论】新安江流域生态资产价值较高,森林与水资源是流域生态系统服务的主要载体,自然禀赋条件对其生态系统服务价值空间分异的影响程度大于社会经济因素。

关键词：生态资产价值生态系统服务价值生态资产质量地理探测器环境地质调查工程新安江流域长江

Research progress on anti-stress nutrition strategies in swine

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Animal Nutrition 2023年第2期13卷 342-360页

作者： leli Wang Chuni Wang Yao Peng Yiru zhang Yuxin Liu Yan Liu Yulong Yin Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjinChina Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation College of Life SciencesHunan Normal UniversityChangshaChina Institute of Subtropical Agriculture Chinese Academy of SciencesChangshaChina

In swine production,stress is a common encounter that leads to serious bacterial infection and adverse effects on growth *** antibiotics have been frequently used to control pathogen spread,sustained negative impacts from antibiotics have been found to affect intestinal integrity and the immune *** nutritional strategies have shown potential to counteract stress and replace antibiotics,including functional amino acids,low protein diet,plant extracts,organic acids,prebiotics,probiotics,minerals and *** additives relieve the stress response in swine via different mechanisms and signal transduction *** on the overview of signaling pathways and stress models,this review highlights the potential of nutritional strategies in swine for preventing or treating stress-related health *** wider application in the pig industry,the dose ranges measured require for further validation in different physiological contexts and *** the future,micro-fluid devices and novel stress models are expected to enhance the efficiency of screening for new anti-stress candidates.

关键词： Nutritional strategy Anti-stress Swine Antibiotic

铁锰铈-PA6基静电纺吸附剂的制备及其对水中铅和铬的吸附性能

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化工新型材料 2024年第1期52卷 207-213,219页

作者：张洛红刘彩琴赵鑫刘建宇杨巧巧王乐力李庆西安工程大学环境科学与工程系西安710600 核工业二〇三研究所咸阳712000

将铁锰铈(Fe-Mn-Ce)负载于PA6静电纺丝上制备抗团聚性强、吸附效果好且易分离回收的新型吸附剂Fe-Mn-Ce-PA6。扫描电子显微镜(SEM)、X射线衍射(XRD)和傅里叶变换红外光谱(FT-IR)分析均显示Fe-Mn-Ce颗粒已成功负载到PA6静电纺丝上。吸附... 详细信息

将铁锰铈(Fe-Mn-Ce)负载于PA6静电纺丝上制备抗团聚性强、吸附效果好且易分离回收的新型吸附剂Fe-Mn-Ce-PA6。扫描电子显微镜(SEM)、X射线衍射(XRD)和傅里叶变换红外光谱(FT-IR)分析均显示Fe-Mn-Ce颗粒已成功负载到PA6静电纺丝上。吸附实验研究结果表明,Fe-Mn-Ce含量为25%时制备的吸附剂对水中Pb(Ⅱ)和Cr(Ⅵ)具有良好的吸附效果,且其在Pb(Ⅱ)初始浓度为10mg/L,吸附剂投加量为0.2g/L,pH为6的条件下对Pb(Ⅱ)的去除率为98%;在Cr(Ⅵ)初始浓度为20mg/L,吸附剂投加量为0.2g/L,pH为6的条件下对Cr(Ⅵ)的去除率为98.5%。该吸附剂对Pb(Ⅱ)和Cr(Ⅵ)的吸附等温模型均符合Freundlich模型,而吸附动力学行为分别符合准一级动力学模型和准二级动力学模型。循环再生实验表明,该吸附剂经五次循环后对Pb(Ⅱ)和Cr(Ⅵ)依然可以保持良好的去除率。

关键词：铁锰铈金属氧化物静电纺丝吸附剂重金属

Two-dimensional coordination polymer-based nanosensor for sensitive and reliable nucleic acids detection in living cells

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Chinese Chemical Letters 2022年第2期33卷 968-972页

作者： Yuzhi Xu Yanfei zhang Huihui Yang Wen Yin leli Zeng Shuo Fang Si-Yang Liu Zong Dai Xiaoyong Zou Yihang Pan Precision Medicine Center Scientific Research CenterThe Seventh Affiliated HospitalSun Yat-sen UniversityShenzhen 518107China Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province School of Biomedical EngineeringSun Yat-sen UniversityGuangzhou 510006China School of Chemistry Sun Yat-sen UniversityGuangzhou 510275China Department of Oncology The Seventh Affiliated HospitalSun Yat-sen UniversityShenzhen 518107China

A reliable and sensitive strategy which can assess nucleic acid levels in living cells would be essential for fundamental research of biomedical applications. Some nanomaterial-based fluorescence biosensors recently developed for detecting nucleic acids, however, are often with expensive, complicated and timeconsuming preparation process. Here, by using a facile bottom-up synthesis method, a two-dimensional(2 D) coordination polymer(CP) nanosheet, [Cu(tz)](Htz = 1,2,4-triazole), was successfully prepared after optimizing reaction conditions. These ultrathin CP nanosheets with thickness of 4.7 ± 1.1 nm could readily form nanosensors by assembly with DNA probes, which exhibited a low limit of detection(LOD)for p53 DNA fragment as 144 pmol/L. Furthermore, by integrating [Cu(tz)] nanosheets with hybridization chain reaction(HCR) probes, mi R-21, one kind of micro RNA upregulated in many cancer cells, can be sensitively detected with a LOD of 100 pmol/L and monitored in living cells, giving consistent results with those obtained by quantitative reverse-transcription polymerase chain reaction(q RT-PCR) *** [Cu(tz)] nanosheets, which not only possess much better nucleic acids sensing performance than bulk cystals, but also exhibit nucleic acid delivery functions, could be used as a novel nanoplatform in biomedical imaging and sensing applications.

关键词： Coordination polymers Nanosheets Fluorescence biosensor Nucleic acids detection Living cells

Epitranscriptomics and epiproteomics in cancer drug resistance:therapeutic implications

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Signal Transduction and Targeted Therapy 2020年第1期5卷 865-880页

作者： Huibin Song Dongcheng Liu Shaowei Dong leli Zeng Zhuoxun Wu Pan Zhao Litu zhang Zhe-Sheng Chen Chang Zou Shenzhen People’s Hospital(The Second Clinical Medical College Jinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)Shenzhen 518001 GuangdongChina College of Pharmacy and Health Sciences St.John’s UniversityQueens11439 New YorkUSA Tomas Lindahl Nobel Laureate Laboratory Research CentreThe Seventh Affiliated HospitalSun Yat-sen UniversityShenzhen 518107 GuangdongChina Department of Research Affiliated Tumor Hospital of Guangxi Medical UniversityNanning 530021 GuangxiChina Shenzhen Public Service Platform on Tumor Precision Medicine and Molecular Diagnosis Shenzhen 518001 GuangdongChina

Drug resistance is a major hurdle in cancer treatment and a key cause of poor *** and epiproteomics are crucial in cell proliferation,migration,invasion,and epithelial–mesenchymal *** recent years,epitranscriptomic and epiproteomic modification has been investigated on their roles in overcoming drug *** this review article,we summarized the recent progress in overcoming cancer drug resistance in three novel aspects:(i)mRNA modification,which includes alternative splicing,A-to-I modification and mRNA methylation;(ii)noncoding RNAs modification,which involves miRNAs,lncRNAs,and circRNAs;and(iii)posttranslational modification on molecules encompasses drug inactivation/efflux,drug target modifications,DNA damage repair,cell death resistance,EMT,and *** addition,we discussed the therapeutic implications of targeting some classical chemotherapeutic drugs such as cisplatin,5-fluorouridine,and gefitinib via these *** together,this review highlights the importance of epitranscriptomic and epiproteomic modification in cancer drug resistance and provides new insights on potential therapeutic targets to reverse cancer drug resistance.

关键词： therapeutic cancer drug

Gut microbiota bridges dietary nutrients and host immunity

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Science China(Life Sciences) 2023年第11期66卷 2466-2514页

作者： Lijuan Fan Yaoyao Xia Youxia Wang Dandan Han Yanli Liu Jiahuan Li Jie Fu leli Wang Zhending Gan Bingnan Liu Jian Fu Congrui Zhu Zhenhua Wu Jinbiao Zhao Hui Han Hao Wu Yiwen He Yulong Tang Qingzhuo zhang Yibin Wang Fan zhang Xin Zong Jie Yin Xihong Zhou Xiaojun Yang Junjun Wang Yulong Yin Wenkai Ren Guangdong Laboratory of Lingnan Modern Agriculture National Engineering Research Center for Breeding Swine IndustryCollege of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642China State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China College of Animal Science and Technology Northwest A&F UniversityXi’an 712100China State Key Laboratory of Agricultural Microbiology College of Veterinary MedicineHuazhong Agricultural UniversityWuhan 430070China College of Animal Sciences Zhejiang UniversityHangzhou 310058China Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China Institute of Animal Sciences Chinese Academy of Agricultural SciencesBeijing 100081China Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation College of Life SciencesHunan Normal UniversityChangsha 410081China College of Animal Science and Technology Hunan Agricultural UniversityChangsha 410128China

Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and entrain each other,and thus affect host health and immune-mediated ***,we systematically review the current understanding linking dietary nutrients to gut microbiota-host immune interactions,emphasizing how this axis might influence host immunity in health and *** relevance,we highlight that the implications of gut microbiota-targeted dietary intervention could be harnessed in orchestrating a spectrum of immune-associated diseases.

关键词： amino acid carbohydrate lipid trace element vitamin gut microbiota immunity