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A Task-oriented Modular and Agent-based Collaborative Design Mechanism for Distributed Product Development

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Chinese Journal of Mechanical Engineering 2014年第3期27卷 641-654页

作者： LIU Jinfei CHEN ming wang lei WU Qidi School of Electronics and Information Engineering Tongji University School of Mechanical Engineering Tongji University

The rapid expansion of enterprises makes product collaborative design （PCD） a critical issue under the distributed heterogeneous environment, but as the collaborative task of large-scale network becomes more complicated, neither unified task decomposition and allocation methodology nor Agent-based network management platform can satisfy the increasing demands. In this paper, to meet requirements of PCD for distributed product development, a collaborative design mechanism based on the thought of modularity and the Agent technology is presented. First, the top-down 4-tier process model based on task-oriented modular and Agent is constructed for PCD after analyzing the mapping relationships between requirements and functions in the collaborative design. Second, on basis of sub-task decomposition for PCD based on a mixed method, the mathematic model of task-oriented modular based on multi-objective optimization is established to maximize the module cohesion degree and minimize the module coupling degree, while considering the module executable degree as a restriction. The mathematic model is optimized and simulated by the modified PSO, and the decomposed modules are obtained. Finally, the Agent structure model for collaborative design is put forward, and the optimism matching Agents are selected by using similarity algorithm to implement different task-modules by the integrated reasoning and decision-making mechanism with the behavioral model of collaborative design Agents. With the results of experimental studies for automobile collaborative design, the feasibility and efficiency of this methodology of task-oriented modular and Agent-based collaborative design in the distributed heterogeneous environment are verified. On this basis, an integrative automobile collaborative R＆D platform is developed. This research provides an effective platform for automobile manufacturing enterprises to achieve PCD, and helps to promote product numeralization collaborative R＆D and manag

关键词： collaborative design task-oriented modular multi-agent collaboration mechanism collaborative platform

Truncated Gauss-Newton full-waveform inversion of pure quasi-P waves in vertical transverse isotropic media

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Petroleum Science 2024年第5期21卷 3102-3124页

作者： Zhi-ming Ren lei wang Qian-Zong Bao College of Geological Engineering and Geomatics Chang'an UniversityXi'an710064ShaanxiChina National Engineering Research Center of Offshore Oil and Gas Exploration Beijing100028China

Full-waveform inversion(FWI) uses the full information of seismic data to obtain a quantitative estimation of subsurface physical parameters. Anisotropic FWI has the potential to recover high-resolution velocity and anisotropy parameter models, which are critical for imaging the long-offset and wideazimuth data. We develop an acoustic anisotropic FWI method based on a simplified pure quasi P-wave(qP-wave) equation, which can be solved efficiently and is beneficial for the subsequent *** the inverse Hessian operator to precondition the functional gradients helps to reduce the parameter tradeoff in the multi-parameter inversion. To balance the accuracy and efficiency, we extend the truncated Gauss-Newton(TGN) method into FWI of pure qP-waves in vertical transverse isotropic(VTI) media. The inversion is performed in a nested way: a linear inner loop and a nonlinear outer *** derive the formulation of Hessian-vector products for pure qP-waves in VTI media based on the Lagrange multiplier method and compute the model update by solving a Gauss-Newton linear system via a matrix-free conjugate gradient method. A suitable preconditioner and the Eisenstat and Walker stopping criterion for the inner iterations are used to accelerate the convergence and avoid prohibitive computational cost. We test the proposed FWI method on several synthetic data sets. Inversion results reveal that the pure acoustic VTI FWI exhibits greater accuracy than the conventional pseudoacoustic VTI FWI. Additionally, the TGN method proves effective in mitigating the parameter crosstalk and increasing the accuracy of anisotropy parameters.

关键词： Full waveform inversion Anisotropy Pure quasi-P wave Gauss-Newton Hessian

Photosynthetic reaction pathways of natural and artificial systems

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Science China Chemistry 2025年

作者： Shixing lei Liting Bi Lingxuan Chen Zhanting Li Jia Tian State Key Laboratory of Organometallic Chemistry and Shanghai Hong Kong Joint Laboratory in Chemical Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences

Photosynthesis converts solar energy into chemical energy through highly coordinated photosynthetic *** by natural systems,artificial photosynthesis aims to develop an efficient,sustainable,and cost-effective pathway for solar-tochemical *** review examines natural photosynthetic pathways,including retinal/rhodopsin-,bacteriochlorophyll-,and chlorophyll-based systems,highlighting their key components and ***,we outline reaction pathways in artificial photosynthetic systems constructed via heterogeneous,homogeneous,self-assembly,and semi-artificial strategies,focusing on water splitting,carbon fixation,and nitrogen ***,we offer insights into future directions for artificial photosynthesis,emphasizing the importance of using self-assembly strategies and the potential of using primitive phototrophic microorganisms as models.

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The potential mechanism and clinical application value of remote ischemic conditioning in stroke

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Neural Regeneration Research 2025年第6期20卷 1613-1627页

作者： Yajun Zhu Xiaoguo Li Xingwei lei Liuyang Tang Daochen Wen Bo Zeng Xiaofeng Zhang Zichao Huang Zongduo Guo The First Affiliated Hospital of Chongqing Medical University ChongqingChina

Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved.

关键词： Akt apoptosis autophagy cerebral perfusion cerebral vascular stenosis clinical transformation hemorrhagic stroke ischemic stroke neuroinflammation neuroprotection Notch1 PI3K remote ischemic conditioning stroke

Bifunctional bridging capping layer enables 24.5% efficiency of perovskite solar cells with polymer-based hole transport materials

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Science China Chemistry 2025年第1期 350-359页

作者： Can Zhu Yiyang wang lei Meng Beibei Qiu Jing Li Shucheng Qin Ke Hu Xin Jiang Wenbin Lai Minchao Liu Zhe Liu Chenxing Lu Jinyuan Zhang Yongfang Li Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences School of Chemical Science University of Chinese Academy of Sciences Key Laboratory of Solid State Optoelectronic Devices of Zhejiang Province College of Physics and Electronic Information Engineering Zhejiang Normal University Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of Sciences Laboratory of Advanced Optoelectronic Materials College of Chemistry Chemical Engineering and Materials ScienceSoochow University

Developing a bridge capping layer between perovskite and hole transport layer materials（HTMs） in the n-i-p perovskite solar cells（pero-SCs） is an effective approach to modify the morphology of HTMs and passivate the perovskite ***, we select the quinoxaline-based bifunctional passivation agent, quinoxalin-6-yl-methylamine hydrochloride（Qx MACl）,as the bridging layer, and a D-A copolymer PBQ12 containing the same quinoxaline unit as an HTM for the n-i-p pero-SCs. Due to the π-π stacking among the common quinoxaline units in the bridge layer and HTM, Qx MACl induces the π-π stacking of the PBQ12 film and improves the film morphology of HTMs with better conductivity. Additionally, Qx MACl can effectively passivate the perovskite surface, and PBQ12 possesses appropriate energy levels and high hole mobility. The pero-SCs based on FAPbI3with PBQ12/Qx MACl treatment showed a higher power conversion efficiency（PCE） of 24.05% and outstanding stability, maintaining 95.4% and 92.1% of its initial PCE after 750 h of storage and after over 800 h of thermal annealing at 85 °C, respectively. To further enhance the PCE of the PBQ12/Qx MACl-based devices, we developed a non-metal ion dopant for the PBQ12 HTM. Through trace doping of PBQ12 HTM by the non-metal ion dopant, the PCE of the PBQ12/Qx MACl-based devices reached 25.24%（the calibrated PCE of 24.55% by the National Institute of Metrology, China）.

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磁性纳米材料与磁场效应加速骨损伤修复

中国组织工程研究 2025年第4期29卷 827-838页

作者：肖放黄雷王琳华中科技大学同济医学院附属协和医院组织工程与再生医学研究中心湖北省武汉市430022 华中科技大学同济医学院附属协和医院检验科湖北省武汉市430022

背景:磁性纳米材料具有促进干细胞成骨分化和抑制破骨细胞形成等生物活性,并在磁场协同下有效促进损伤骨组织愈合,在骨损伤修复中具有广阔的应用前景。目的:综述磁性纳米材料与磁场促进骨修复的作用机制,及其在骨损伤修复领域的研究进... 详细信息

背景:磁性纳米材料具有促进干细胞成骨分化和抑制破骨细胞形成等生物活性,并在磁场协同下有效促进损伤骨组织愈合,在骨损伤修复中具有广阔的应用前景。目的:综述磁性纳米材料与磁场促进骨修复的作用机制,及其在骨损伤修复领域的研究进展。方法:在PubMed和Web of Science数据库中进行相关文献检索,检索词为“magnetic nanomaterials,magnetic field,bone repair,bone tissue engineering,stem cell,osteoblast,osteoclast”。检索文献时限为2003-2023年,将其进行筛选和分析,最终纳入98篇文献进行分析。结果与结论:①磁性纳米材料具有促成骨细胞分化、抑制破骨细胞形成和调节免疫微环境等生物效应;此外,磁性纳米材料可调节组织工程支架的机械性能和表面形貌等理化性质,并赋予其磁性,有利于调控干细胞的黏附、增殖与成骨分化。②磁场具有调控细胞内多条信号通路发挥促成骨细胞分化、抑制破骨细胞形成和刺激血管生成等生物学效应,从而加速损伤的骨组织愈合。③磁性纳米材料与磁场的联合应用,通过激活机械转导、增加细胞内磁性纳米粒子含量、增强微磁场效应等加速骨损伤修复,为骨组织工程的研究提供了新的思路。④磁场在临床骨折、骨质疏松症和骨关节炎疾病的治疗中展现出确切疗效,促进骨组织生长、减轻骨质流失和缓解疼痛,改善患者的生活质量。⑤磁性纳米材料与磁场在骨损伤修复与再生中应用潜力大,但磁性纳米材料、磁场和细胞之间的相互作用机制尚未完全阐明,而且磁场调控细胞内分子事件的关键参数,包括磁场类型、强度、频率、作用时间和作用方式等,以及特定磁场对骨细胞的精确生物效应和潜在机制仍有待明确。⑥未来需要进一步关注其对损伤组织微环境中的破骨细胞、神经、血管和免疫细胞的影响,而关于磁性材料用于人体安全性问题,有待系统性研究其分布、代谢以及急性和慢性毒性等。

关键词：磁性纳米材料磁场骨修复骨组织工程干细胞成骨细胞破骨细胞

RepColor: deep coloring algorithm combining semantic categories

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Optoelectronics Letters 2025年

作者： lei Sun Dongjie Ju School of Electrical Engineering and Automation， Tianjin University of Technology Tianjin Key Laboratory for Control Theory and Complicated Industry Systems， Tianjin University of Technology

Image coloring is an inherently uncertain and multimodal problem. By inputting a grayscale image into a coloring network， visually plausible colored photos can be generated. Conventional methods primarily rely on semantic information for image colorization. Although effective in coloring images with clear semantic information， these methods still suffer from color contamination and semantic confusion. This is largely due to the limited capacity of convolutional neural networks to effectively learn deep semantic information inherent in *** this paper， we propose a network structure that addresses these limitations by leveraging multi-level semantic information classification and fusion. Additionally， we introduce a global semantic fusion network to combat the issues of color contamination. The proposed coloring encoder accurately extracts object-level semantic information from *** further enhance visual plausibility， we employ a self-supervised adversarial training method. We train the network structure on various datasets with varying amounts of data and evaluate its performance using the ImageNet validation set and COCO validation set. Experimental results demonstrate that our proposed RepColor can generate more realistic images compared to previous approaches， showcasing its high generalization ability.

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An adaptive multi-population genetic algorithm for job-shop scheduling problem

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Advances in Manufacturing 2016年第2期4卷 142-149页

作者： lei wang Jing-Cao Cai ming Li School of Mechanical and Automotive Engineering AnhuiPolytechnic University Wuhu 241000People's Republic of China

Job-shop scheduling problem （JSP） is a typical NP-hard combinatorial optimization problem and has a broad background for engineering application. Nowadays, the effective approach for JSP is a hot topic in related research area of manufacturing system. However, some JSPs, even for moderate size instances, are very difficult to find an optimal solution within a reasonable time because of the process constraints and the complex large solution space. In this paper, an adaptive multi-population genetic algorithm （AMGA） has been proposed to solve this prob- lem. Firstly, using multi-populations and adaptive cross- over probability can enlarge search scope and improve search performance. Secondly, using adaptive mutation probability and elite replacing mechanism can accelerate convergence speed. The approach is tested for some clas- sical benchmark JSPs taken from the literature and com- pared with some other approaches. The computational results show that the proposed AMGA can produce optimal or near-optimal values on almost all tested benchmark instances. Therefore, we can believe that AMGA can be considered as an effective method for solving JSP.

关键词： Job-shop scheduling problem (JSP) Adaptive crossover Adaptive mutation Multi-population Elite replacing strategy

松辽盆地北部安达凹陷生烃灶独立性研究及其石油地质意义

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维普期刊数据库

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石油学报 2010年第2期31卷 211-217页

作者：雷明王建功王天琦史忠生刘彩艳韩小强吴伟航中国石油勘探开发研究院西北分院甘肃兰州730020 中国科学院兰州地质研究所甘肃兰州730020

安达凹陷毗邻松辽盆地北部的三肇凹陷,具有良好的石油地质条件,近年安达凹陷中浅层已经显示出较好的油气勘探潜力。多年来,油源问题制约着该区的油气勘探进程。本文通过平衡剖面方法,开展安达凹陷与其南部三肇凹陷、北部黑鱼泡凹陷、西... 详细信息

安达凹陷毗邻松辽盆地北部的三肇凹陷,具有良好的石油地质条件,近年安达凹陷中浅层已经显示出较好的油气勘探潜力。多年来,油源问题制约着该区的油气勘探进程。本文通过平衡剖面方法,开展安达凹陷与其南部三肇凹陷、北部黑鱼泡凹陷、西面大庆长垣、东面明水阶地等周边构造带演化关系的对比研究,结合地球化学指标,提出安达向斜在构造上是一个独立的凹陷,具备形成独立生烃灶的次级含油气系统。在此基础上,指出安达凹陷西部、北部构造带具有极大勘探潜力,其中断层—岩性油气藏是下一步油气勘探的主要方向。

关键词：松辽盆地北部安达凹陷独立生烃灶平衡剖面油源对比