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Typical imaging manifestation of neuronal intranuclear inclusion disease in a man with unsteady gait:A case report

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World Journal of Clinical Cases 2022年第33期10卷 12388-12394页

作者： Xue Gao Zhi-Ding Shao lei zhu Department of Neurology The Second Affiliated Hospital of Wannan Medical CollegeWuhu 241000Anhui ProvinceChina Department of Neurology Huainan First People’s Hospital Affiliated to Auhui University of Science and TechnologyHuainan 232000Anhui ProvinceChina

BACKGROUND Neuronal intranuclear inclusion disease(NIID)is a rare neurological degenerative disorder with diverse manifestations and inadequate *** a few cases of NIID have been reported,and typical imaging findings can provide certain clues for the diagnosis of the ***,skin biopsy and genetic testing are important to confirm the *** SUMMARY An 84-year-old man presented to the Neurology Department of our hospital complaining of a progressive course of cognitive impairment and unsteady gait for 2 *** symptoms gradually progressed and affected his daily *** patient was initially diagnosed with Parkinson’s disease and vascular *** patient did not respond to conventional treatment,such as ***,magnetic resonance imaging(MRI)was *** on the imaging findings,we suspected an NIID *** the 3-year follow-up in our hospital,his clinical symptoms gradually progressed,and imaging findings became more significant.A high signal intensity along the corticomedullary junction persisted on *** testing and skin biopsy were recommended in our hospital;however,the patient refused these *** was also considered when he went to a superior hospital in *** patient eventually agreed to undergo gene *** revealed abnormal GGC repeat expansions in the NOTCH2NLC *** The clinical manifestations of NIID are *** with clinical manifestations similar to Parkinson’s disease and dementia may have NIID.

关键词： Gait Neuronal intranuclear inclusion disease Magnetic resonance imaging Biopsy Genetics Case report

Efficient Formation of Large Chain Carbon Clusters

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Chinese Physics Letters 1994年第8期11卷 488-490页

作者： zhu lei LU Jianzhong WU Meiping LI Yufen Fudan-T.D.Lee Physics Laboratory Laboratory of Laser Physics and OpticsDepartment of PhysicsFudan UniversityShanghai 200433

We find that bare C_(n)^(-) clusters favor chain structure from n=4 up to 43 by laser desorption mass spectrometric study of C60 admixed with polystyrene,whereas both one-and two-dimensional structures should coexist ... 详细信息

关键词： desorption polystyrene Chain

表观遗传学变化及运动调控:改善骨骼肌衰老的机制

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中国组织工程研究 2025年第2期29卷 419-429页

作者：樊饶孔健达李琳翟腾杨紫柔朱磊曲阜师范大学体育科学学院山东省济宁市272000

背景:骨骼肌衰老和多种表观遗传学变化密切相关,运动对这些表观遗传学变化具有一定调控作用,但尚不完全了解其具体机制。目的:回顾骨骼肌的表观遗传学机制以及运动如何通过这些表观遗传学机制来改善骨骼肌的衰老,并促进肌肉的适应性变化... 详细信息

背景:骨骼肌衰老和多种表观遗传学变化密切相关,运动对这些表观遗传学变化具有一定调控作用,但尚不完全了解其具体机制。目的:回顾骨骼肌的表观遗传学机制以及运动如何通过这些表观遗传学机制来改善骨骼肌的衰老,并促进肌肉的适应性变化,旨在更全面地认识骨骼肌老化和疾病机制。方法:于2023-06-01/08-01检索自建库至2023年8月的Web of Science、PubMed、中国知网(CNKI)、万方和维普等数据库,中文检索词包括骨骼肌、肌肉、衰老、老年、老化、运动、体育锻炼、表观遗传、表观遗传学等;英文检索词包括skeletal muscle,muscle,aging,older adult,senescence,older adult,age,exercise,sports,physical activity,physical activity,epigenetic,epigenetics等。运用布尔逻辑运算符将检索词连接并进行检索,并制定了相应的策略。根据预定的纳入和排除标准,最终筛选出70篇符合条件的文献。结果与结论:①表观遗传学是指基因序列不发生改变的情况下,基因表达和功能受到调控的现象,其中骨骼肌的表观遗传学变化是一个重要的领域;②骨骼肌的表观遗传学机制在肌肉衰老过程中起着重要作用,主要涉及DNA甲基化、组蛋白修饰、非编码RNA的调控、染色质重塑、线粒体功能改变和衰老相关基因的表达改变等;③运动显著调控骨骼肌表观遗传学,包括运动促进骨骼肌DNA甲基化、骨骼肌组蛋白修饰、调控骨骼肌miRNA、调控骨骼肌长链非编码RNAs、调控肌肉因子(白细胞介素6的作用)、调控骨骼肌线粒体功能(过氧化物酶体增殖剂激活受体γ共激活因子1α的作用);④建议未来开展:长期、跨不同群体的运动干预研究;应用多组学技术,如蛋白组学和代谢组学;加强对单个细胞水平上表观遗传学变化;开展跨物种的比较研究以及人体临床试验将动物模型的发现转化到人类;研究运动与药理学干预相结合的策略评估两者的协同效果;开展骨骼肌和不同器官之间串扰交互作用的表观遗传学研究。

关键词：骨骼肌衰老表观遗传学变化运动调控 DNA甲基化组蛋白修饰线粒体功能

AMPLIFICATION OF TUNABLE HIGH REPETITION PICOSECOND PULSE FROM SHORT CAVITY DYE LASERS

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Chinese Physics Letters 1990年第12期7卷 548-551页

作者： zhu lei QIAN Liejia ZHANG Guiyan LIN Fucheng Shanghai Institute of Optics and Fine Mechanics Academia SinicaShanghai 201800

It is reported here that synchronous amplification and tuning of 30ps pulses from the short cavity dye laser pumped by copper bromide laser have been achieved by a dye amplifier-dispersion *** can be tuned continuousl... 详细信息

关键词： amplifier tuning pumped

Empirical Likelihood for Quantiles Under Associated Samples

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Acta Mathematicae Applicatae Sinica 2015年第1期31卷 71-80页

作者： Ying-hua LI Yong-song QIN Qing-zhu lei School of Mathematics and Statistics Guangxi Normal University

The construction of confidence intervals for quantiles of a population under a associated sample is studied by using the blockwise technique. It is shown that the blockwise empirical likelihood （EL） ratio statistic is asymptotically X2-type distributed, which is used to obtain EL-based confidence intervals for quantiles of a population.

关键词： quantile associated sample blockwise empirical likelihood confidence interval

MSCNN-LSTM Model for Predicting Return Loss of the UHF Antenna in HF-UHF RFID Tag Antenna

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Computers, Materials & Continua 2023年第5期75卷 2889-2904页

作者： Zhao Yang Yuan Zhang lei zhu lei Huang Fangyu Hu Yanping Du Xiaowei Li School of Mechanical and Electrical Engineering Beijing Institute of Graphic CommunicationBeijing102600China Postal Industry Technology R&D Center Beijing Institute of Graphic CommunicationBeijing102600China Collage of Electronic Information and Automation Civil Aviation University of ChinaTianjin300300China

High-frequency(HF)and ultrahigh-frequency(UHF)dual-band radio frequency identification(RFID)tags with both near-field and farfield communication can meet different application ***,it is time-consuming to calculate the return loss of a UHF antenna in a dualband tag antenna using electromagnetic(EM)*** overcome this,the present work proposes a model of a multi-scale convolutional neural network stacked with long and short-term memory(MSCNN-LSTM)for predicting the return loss of UHF antennas instead of EM *** the proposed MSCNN-LSTM,the MSCNN has three branches,which include three convolution layers with different kernel sizes and ***,MSCNN can extract fine-grain localized information of the antenna and overall *** LSTM can effectively learn the EM characteristics of different structures of the antenna to improve the prediction accuracy of the *** results show that the mean absolute error(0.0073),mean square error(0.00032),and root mean square error(0.01814)of theMSCNNLSTM are better than those of other prediction *** predicting the return loss of 100UHFantennas,compared with the simulation time of 4800 s for High Frequency Structure Simulator(HFSS),MSCNN-LSTM takes only 0.927519 s under the premise of ensuring prediction accuracy,significantly reducing the calculation time,which provides a basis for the rapid design of HF-UHF RFID tag ***-LSTM is used to determine the dimensions of the UHF antenna *** return loss of the designed dualband RFID tag antenna is−58.76 and−22.63 dB at 13.56 and 915 MHz,respectively,achieving the desired goal.

关键词： HF-UHF RFID tag antenna multi-scale convolutional neural network long-short term memory return loss

Effect of carbon addition on stress rupture properties of a cast TiAl alloy

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Journal of Iron and Steel Research International 2019年第3期26卷 268-274页

作者： Xi-wen Zhang Yu-ling Tang Chun-lei zhu Ji Zhang Beijing Key Laboratory of Advanced High Temperature Materials China Iron and Steel Research Institute Group Beijing 100081 China National Center for Electron Microscopy in Beijing School of Materials Science and Engineering Tsinghua University Beijing 100084 China

Two TiAl alloys,Ti^47.5Al-3.7(Cr,V,Zr)and Ti77.5Al-3.7(Cr,V,Zr)-0.1C(at.%),were melted and cast with the same process,*** with strongly oriented lamellae were both observed in these two alloys followed by hot isostatic pressing and heat ***2AlC carbides were identified in the alloy with C *** rupture tests were carried out at 800 and 850°C,with tensile stress from 220 to 400 MPa,*** was shown that the alloy with C experienced much longer lives than the other,especially under the condition of 800°C/260 MPa,800°C/300 MPa,850°C/220 MPa,850°C/240 MPa and 850°C/260 *** of ruptured specimens revealed that the microstructure stability was improved significantly in the alloy with C addition which is attributed to the strengthening effect of Ti-Al-C *** Ti2AlC carbides mainly increased the resistance of dislocation passing through the interfaces and kept the integrity of the *** Ti3AlC carbide was formed during stress rupture process,which could not only effectively act as the barrier of dislocation movement inside the lamellae,but also strengthen the lamellae itself.

关键词： Titanium aluminide Carbon addition Stress rupture property Dynamic precipitated carbide

Expression Complementary Disentanglement Network for Facial Expression Recognition

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Chinese Journal of Electronics 2024年第3期33卷 742-752页

作者： Shanmin WANG Hui SHUAI lei zhu Qingshan LIU College of Computer Science and Technology Nanjing University of Aeronautics and Astronautics College of Computer and Software Nanjing University of Information Science and Technology School of Information and Control Nanjing University of Information Science and Technology

Disentangling facial expressions from other disturbing facial attributes in face images is an essential topic for facial expression *** methods only care about facial expression disentanglement(FED)itself,ignoring the negative effects of other facial *** to the annotations on limited facial attributes,it is difficult for existing FED solutions to disentangle all disturbance from the input *** solve this issue,we propose an expression complementary disentanglement network(ECDNet).ECDNet proposes to finish the FED task during a face reconstruction process,so as to address all facial attributes during *** from traditional reconstruction models,ECDNet reconstructs face images by progressively generating and combining facial appearance and matching *** designs the expression incentive(EIE) and expression inhibition(EIN) mechanisms,inducing the model to characterize the disentangled expression and complementary parts *** geometry and appearance,generated in the reconstructed process,are dealt with to represent facial expressions and complementary parts,*** combination of distinctive reconstruction model,EIE,and EIN mechanisms ensures the completeness and exactness of the FED *** results on RAF-DB,AffectNet,and CAER-S datasets have proven the effectiveness and superiority of ECDNet.

关键词： Geometry Image recognition Annotations Face recognition Task analysis Image reconstruction Facial features

Image Salient Region Detection Based on the Learning of Feature Distribution 36

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Image Salient Region Detection Based on the Learning of Feat...