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Strong,tough,and thermally conductive nacre-inspired boron nitride nanosheet/epoxy layered nanocomposites

Nano Research 2024年第2期17卷 820-828页

作者： Huagao Wang Rongjian Lu lei Li Cheng Liang Jia Yan Rui Liang Guoxing Sun lei jiang Qunfeng Cheng School of chemistry Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of EducationBeihang UniversityBeijing 100191China School of chemistry and Materials Science University of Science and Technology of ChinaHefei 230026China Suzhou institute for Advanced Research University of Science and Technology of ChinaSuzhou 215123China Department of Stomatology Fifth Medical CenterChinese PLA General HospitalBeijing 100039China Department of Engineering Science Faculty of Innovation EngineeringMacao University of Science and TechnologyAvenida Wai LongTaipaMacao 999078 China Joint Key Laboratory of the Ministry of Education Institute of Applied Physics and Materials EngineeringUniversity of MacaoAvenida da UniversidadeTaipaMacao 999078China institute of Energy Materials Science(IEMS) University of Shanghai for Science and TechnologyShanghai 200093China

Thermally conductive polymer nanocomposites integrated with lightweight,excellent flexural strength,and high fracture toughness(KIc)would be of great use in many ***,achieving all of these properties simultaneously remains a great *** by natural nacre,here we demonstrate a lightweight,strong,tough,and thermally conductive boron nitride nanosheet/epoxy layered(BNNEL)*** of the layered structure and enhancing the interfacial interactions through hydrogen bonding and Si–O–B covalent bonding,the resulting nacre-inspired BNNEL nanocomposites show high fracture toughness of~4.22 MPa·m^(1/2),which is 7 folds as high as pure ***,the BNNEL nanocomposites demonstrate sufficient flexural strength(~168.90 MPa,comparable to epoxy resin),while also being lightweight(~1.23 g/cm^(3)).Additionally,the BNNEL nanocomposites display a thermal conductivity(κ)of~0.47 W/(m·K)at low boron nitride nanosheet loading of 2.08 vol.%,which is 2.7 times higher than that of pure epoxy *** developed nacre-inspired strategy of layered structure design and interfacial enhancement provides an avenue for fabricating high mechanical properties and thermally conductive polymer nanocomposites.

关键词： nacre-inspiration nanocomposites flexural strength fracture toughness(KIc) thermal conductivity

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Evolving molecular subtyping of breast cancer advances precision treatment

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Cancer Biology & Medicine 2024年第9期21卷 731-739页

作者： Rui Shan lei-Jie Dai Zhi-Ming Shao Yi-Zhou jiang Department of Breast Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China

Breast cancer is the second most prevalent cancer *** 2022,approximately 2.3 million newly diagnosed cases of female breast cancer occurred worldwide,and more than 665 thousand people lost their lives to this disease^... 详细信息

关键词： breast cancer Breast

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Bio-Inspired,Smart,Multiscale Interfacial Materials

Bio-Inspired,Smart,Multiscale Interfacial Materials

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中国化学会第27届学术年会

作者： lei jiang center of molecular sciences institute of chemistry chinese academy of sciences beijing 100190 china

＜正＞Bio-inspired smart materials should be a "live" material with various functions like organism in Nature, they must have three essential elements as sense, drive and control. The studies

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The Effect and Mechanism of Fructus lycii on Improvement of Exercise Fatigue Using a Network Pharmacological Approach with in vitro Experimental Verification

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Biomedical and Environmental sciences 2024年第1期37卷 42-53页

作者： JI Xiao Ning LIU Zhao Ping ZHANG Chao Zheng CHEN Min LIANG jiang LU jiang ZHANG lei National Resource center for chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China china National center for Food Safety Risk Assessment Beijing 100022China chinese center for Disease Control and Prevention Beijing 102206China

Objective This study aimed to investigate the effect and underlying mechanism of Fructus lycii in improving exercise *** A network pharmacological approach was used to explore potential mechanisms of action of Fructus *** muscle C2C12 cells and immunofluorescence were employed to verify the effect and mechanism of the representative components in Fructus lycii predicted by network pharmacological *** Six potential active components,namely quercetin,β-sitosterol,stigmasterol,7-Omethylluteolin-6-C-beta-glucoside_qt,atropine,and glycitein,were identified to have potency in improving exercise fatigue via multiple pathways,such as the PI3K-Akt,neuroactive ligand-receptor interaction,IL-17,TNF,and MAPK signaling *** immunofluorescence results indicated that quercetin,a significant active component in Fructus lycii,increased the mean staining area of 2-NBDG,TMRM,and MitoTracker,and decreased the area of CellRox compared to the ***,the protein expression levels of p-38 MAPK,p-MAPK,p-JNK,p-PI3K,and p-AKT markedly increased after quercetin *** Fructus lycii might alleviate exercise fatigue through multiple components and *** these,quercetin appears to improve exercise fatigue by enhancing energy metabolism and reducing oxidative *** PI3K-AKT and MAPK signaling pathways also appear to play a role in this process.

关键词： Fructus lycii Exercise fatigue Network pharmacology

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Colossal magnetoresistive p-n junctions of perovskite oxide La_(0.9)Sr_(0.1)MnO_3/SrNb_(0.01)Ti_(0.99)O_3

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chinese Science Bulletin 2003年第13期48卷 1328-1330页

作者： L Huibin, DAI Souyu, CHEN Zhenghao, YAN lei, ZHOU Yueliang & YANG Guozhen Laboratory of Optical Physics, institute of Physics & center for Condensed Matter Physics, chinese academy of sciences, 100080 beijing, china Laboratory of Optical Physics Center for Condensed Matter Physics Chinese Academy of Sciences 100080 Beijing China

We have successfully fabricated the colossal magnetoresistive (CMR) p-n junctions of perovskite oxide La0.9Sr0.1MnO3/SrNb0.01Ti0.99O3 (LSMO/SNTO) with laser molecular beam epitaxy. The I-V characteristics of the LSMO/SNTO p-n junctions as a function of applied magnetic field (05 T) were studied between 100 and 300 K. We found that the p-n junction exhibited the CMR behavior. The CMR ratio rR/R0 (rR = RH - R0) is positive in magnetic fields below 0.13 T and at high temperature, while it displays a negative CMR near 100 K and in magnetic fields over 0.13 T. The CMR ratio values are 8% at 0.1 T and 13% at 5 T and 300 K, 40% at 0.1 T and 150 K, 10% at 0.13 T and 60% at 5 T and 100 K. The CMR behavior of the p-n junction is different from those of the LaMnO3 compound family.

关键词：巨磁电阻钙钛矿氧化物 LSMO/SNTO CMR 激光分子束外延超导体

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Biomimetic preparation of elastomeric fibers with micro/nano structures on the surfaces

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Progress in Natural Science:Materials International 2012年第5期22卷 493-501页

作者： Quanyong Liu a,Liqun Zhang c,lei jiang a,b a Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education,School of chemistry and Environment,Beihang University,beijing 100191,PR china b beijing National Laboratory for molecular sciences(MNLMS),Key Laboratory of Organic Solids,institute of chemistry,chinese academy of sciences,beijing 100190,PR china c State Key Laboratory of Organic-Inorganic Composites,beijing University of Chemical Technology,beijing 100029,PR china Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education School of Chemistry and Environment Beihang University Beijing 100191 PR China State Key Laboratory of Organic–Inorganic Composites Beijing University of Chemical Technology Beijing 100029 PR China beijing National Laboratory for molecular sciences (MNLMS) Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences Beijing 100190 PR China

Bioinspired by the spinning of spider silks,the biomimetic preparation of elastomeric fibers with micro/nano structures on the surfaces was attempted,and as a result,three types of ultrafine fullvulcanized powdered nitrile-butadiene rubber(UFPNBR)/thermoplastic polyurethane(TPU) fibers were *** first fiber was only decorated by the micron-sized grooves on the surface,and the second fiber was dotted by both the micron-sized grooves and nanometer-sized spheres on the surface,while the third fiber was helical and with a concave-convex *** biomimetic preparation mainly consisted of four steps,and the formation mechanism was described as an integrated mechanism of diffusion,coagulation,self assembly,and microphase *** micro/nano structures on the fibers were controlled by changing the mass ratio of UFPNBR to TPU and environment of vertical *** UFPNBR/TPU elastomeric fibers were hoped to have an integrated function of superhydrophobicity,self cleaning,and mechanical improvement of toughness or strength.

关键词： Biomimetic preparation Elastomeric fiber Micro/nano structure Self assembly Spider silk

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Bio-inspired Energy Conversion Systems Based on Ion Channel

Bio-inspired Energy Conversion Systems Based on Ion Channel

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第六届全国化学生物学学术会议

作者： lei jiang center of molecular sciences,institute of chemistry,chinese academy of sciences,beijing 100190, P.R.china

＜正＞Inspired by nature,novel functional,multiscale interfacial materials have been developed in our group and correlative work has been reviewed,including relationship between micro- and nanostructures and special w...

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A FRET-Based Ratiometric H_(2)S Sensor for Sensitive Optical molecular Imaging in Second Near-Infrared Window

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Research 2024年第3期2023卷 671-684页

作者： Shan lei Kejia jiang Chenqing Zhang Wei Sun Yuantao Pan Dong Wang Peng Huang Jing Lin Marshall Laboratory of Biomedical Engineering International Cancer CenterShenzhen Key Laboratory of Tumor Visualization Molecular MedicineLaboratory of Evolutionary Theranostics(LET)School of Biomedical EngineeringShenzhen University Medical SchoolShenzhen UniversityShenzhen 518055China. center for AIE Research College of Materials Science and EngineeringShenzhen UniversityShenzhen 518060China.

Second near-infrared(NIR-II)window optical molecular imaging kicks off a new revolution in high-quality imaging in vivo,but always suffers from the hurdles of inevitable tissue autofluorescence background and NIR-II probe ***,we prepare a Förster resonance energy transfer-based ratiometric NIR-II window hydrogen sulfide(H_(2)S)sensor through the combination of an H_(2)S-responsive NIR-II cyanine dye(acceptor,LET-1055)and an H_(2)S-inert rhodamine hybrid polymethine dye(donor,Rh930).This sensor not only exhibits high sensitivity and selectivity,but also shows rapid reaction kinetics(~20 min)and relatively low limit of detection(~96 nM)toward H_(2)S,allowing in vivo ratiometric NIR-II fluorescence imaging of orthotopic liver and colon tumors and visualization of the drug-induced hepatic H_(2)S *** findings provide the potential for advancing the feasibility of NIR-II activity-based sensing for in vivo clinical diagnosis.

关键词： H_ Infrared kinetics

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Progress in materials and technologies for ultrahigh density data storage

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Progress in Natural Science:Materials International 2003年第4期 9-15页

作者： WU Huimeng, SONG Yanlin, WEN Yongqiang, ZHAO Tong, GAO Hongjun and jiang lei (1. center for molecular Science, institute of chemistry, chinese academy of sciences, beijing 100080, china 2. center for Con-densed Matter Physics, institute of Physics, chinese academy of sciences, beijing 100080, china)

With the development of information superhighway, nanometer-scale data storage has been proposed and attracted great interest in recent years. This article reviews the research achievements in this field, and especially focuses on the materials for data record-ing by using an atomic force microscope (AFM) and scanning tunneling microscope (STM).

关键词： ultrahigh densitv data storage nano-electronics scanning probe microscope.

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A submillimeter observation and study of star-forming regions

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chinese Science Bulletin 2002年第1期47卷 16-21页

作者： jiang Linhua, WU Yuefang & M. MillerDepartment of Astronomy, Peking University, beijing 100871, china chinese academy of sciences-Peking University Joint beijing Astrophysics center, beijing 100871, china I. Physikalisches Institut, Zulpicher Str Department of Astronomy Peking University Beijing China chinese academy of sciences-Peking University Joint beijing Astrophysics center Beijing China I. Physikalisches Institut Koeln 41 Germany

Using the 3-m radio telescope of KOSMA, we mapped 12CO (J = 3-2) lines for three molecular clouds, B35, S146 and TMC-2A. High-velocity molecular outflows are found in all these regions. The physical and dynamical pa-rameters of the outflows are derived, and their shapes and driving sources are analyzed. Contour maps of center veloci-ties show that the large scale systematic gradients exist in the three clouds. These observed motions are best explained by rotation after excluding the cause of outflows. Furthermore, in the core region of TMC-2A there is a velocity gradient in opposite direction from that of the large scale. It may be caused by magnetic braking. Finally, angular velocities of the clouds are calculated, and the effects of rotation against gravity and lowering the star-formation rate are also ana-lyzed.

关键词： dynamics of interstellar medium jets and outflows star formation.

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