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振动舒适度的智能手机大数据研究

振动工程学报 2020年第5期33卷 961-970页

作者：曹雷陈隽同济大学土木工程学院上海200092 同济大学土木工程防灾国家重点试验室上海200092

为了解决传统振动舒适度研究方法小样本代表性差、环境非真实等问题,设计了可在智能手机上运行的振动测试和问卷调查程序并开展网络推广,形成了真实环境下、真实感知的振动舒适度大数据调查新方法。通过对已获得的8521条数据进行分析,... 详细信息

为了解决传统振动舒适度研究方法小样本代表性差、环境非真实等问题,设计了可在智能手机上运行的振动测试和问卷调查程序并开展网络推广,形成了真实环境下、真实感知的振动舒适度大数据调查新方法。通过对已获得的8521条数据进行分析,确定了数据清洗的若干标准,利用有效数据研究了受测者身高、年龄、性别、体重等个体特征和发生场所、振动方向、振动原因等环境因素对振动感受的影响,统计了不同特征因素对应的振动限值。研究表明:基于智能手机的振动舒适度大数据研究方法可行,所得结论与已有标准具有一致性,并可包含比传统方法更丰富的影响要素。

关键词：振动舒适度振动限值智能手机大数据真实环境

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旋磁各向异性非均匀球体电磁散射特性

电子科技大学学报 2018年第4期47卷 502-507页

作者：曹雷康凯电子科技大学电子工程学院成都611731

应用T矩阵方法推导了旋磁各向异性径向非均匀球体散射场的解析解。置于自由空间的球形结构被分为N个区域,每个区域的材料参数为标量电导率和旋磁张量磁导率。根据球矢量波函数理论将入射场,散射场以及球体内部各个区域的电磁场展开为球... 详细信息

应用T矩阵方法推导了旋磁各向异性径向非均匀球体散射场的解析解。置于自由空间的球形结构被分为N个区域,每个区域的材料参数为标量电导率和旋磁张量磁导率。根据球矢量波函数理论将入射场,散射场以及球体内部各个区域的电磁场展开为球矢量波函数的线性叠加,最后通过匹配边界条件求得散射系数。雷达散射截面数值结果与有限元方法得到的数值结果有很好的吻合,验证了公式的正确性与有效性。最后给出几个新的算例分析了旋磁非均匀球体的散射特性。

关键词：各向异性媒质电磁散射旋磁媒质 Mie理论矢量波函数

Single-order soft x-ray spectra with spectroscopic photon sieve

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Chinese Physics B 2020年第5期29卷 225-228页

作者： Yu-Lin Gao Lai Wei Qiang-Qiang Zhang Zu-Zua Yang Wei-Min Zhou lei-Feng cao Hi-tech Research and Development Centre China Academy of Engineering PhysicsBeijing 100094China China Jiuyuan Hi-Tech Equipment Corporation Limited Beijing 100094China National Key Laboratory for Laser Fusion Research Center of Laser FusionMianyang 621900China

A single-order diffraction transmission grating named spectroscopic photon sieve(SPS)for soft x-ray region is proposed and demonstrated in this *** SPS consists of many circular pinholes located randomly,and can realize both free-standing diffractions and the suppression of higher-order *** this paper,the basic concept,numerical simulations,and calibration results of a 1000-lines/mm SPS for soft x-ray synchrotron radiation are *** predicted by theoretical calculations,the calibration results of a 1000-lines/mm SPS verify that the higher-order diffractions can be significantly suppressed along the symmetry *** the current nanofabrication technique,the SPS can potentially have a higher line density,and can be widely used in synchrotron radiation,laser-induced plasma diagnostics,and astrophysics.

关键词： higher-order diffraction suppression extreme ultraviolet and soft x-rays single-order diffraction grating

Effects on Proliferation and Migration of the Human Colon Carcinoma Cell Line SW620 by Silencing of Hepatocyte Growth Factor Expression

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Clinical oncology and cancer researeh 2010年第5期7卷 277-283页

作者： Yi-tao JIA lei ZHANG Yan LI Ya-di WANG Wei GUO lei cao Zhong-xin LI 3rd Department of Oncology Hebei ProvincialPepeol's Hospital Shijiazhuang 050051 HebeiProvince China. Department of Histology and Embryology Hebei Medical University Shijiazhuang050017 Hebei Province China Department of Radiotherapy Hebei Medical University Fourth Hospital Shijiazhuang050011 Hebei Province China. 2nd Department of Surgery Hebei Medical University Foruth Hospital Shijiazhuang050011 Hebei Province China.

OBJECTIVE Hepatocyte growth factor （HGF） expression is closely related to the progression and poor prognosis of colorectal cancer patients. In this study, we investigated the effects on proliferation and migration of the human colon carcinoma cell line SW620 by silencing HGF expression. METHODS HGF was silenced using specific HGF a/f3 siRNA. The proliferation, migration, cell cycle and ultrastructure of SW620 cells were examined. RESULTS The transfection efficiency was 70%-80%. The expression rate of HGF in the experimental group was significantly lower than that in the negative and blank control groups （P 〈 0.05）. The proliferation inhibition rate in the experimental group at 24, 48, 72 and 96 h after transfection was 14.2%, 50.2%, 39.5% and 23.2%, respectively. The migratory ability of cells in the experimental group was significantly inhibited compared with that in the negative control or blank control groups （58.2% vs. 2.1% or 0%, P 〈 0.05）. CONCLUSION The application of RNA interference to silence the expression of HGF in the colon carcinoma cell line SW620 effectively inhibits the proliferation and migration of tumor cells.

关键词： RNA interference HGF protein human cellular proliferation cell movement colorectal neoplasms.

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包晶钢连铸坯表面纵裂与保护渣性能选择

钢铁 2015年第2期50卷 38-42页

作者：曹磊济钢集团宽厚板厂山东济南250101

某钢厂宽厚板250 mm×1 820 mm连铸机使用包晶钢类型MB-59型保护渣生产w（C）为0.120%-0.150%钢种时,连铸坯表面出现大量纵向裂纹与皮下裂纹缺陷。通过提高保护渣碱度,降低保护渣黏度,改善铸坯坯壳与结晶器壁之间渣膜传热等技术措施,使... 详细信息

某钢厂宽厚板250 mm×1 820 mm连铸机使用包晶钢类型MB-59型保护渣生产w（C）为0.120%-0.150%钢种时,连铸坯表面出现大量纵向裂纹与皮下裂纹缺陷。通过提高保护渣碱度,降低保护渣黏度,改善铸坯坯壳与结晶器壁之间渣膜传热等技术措施,使铸坯的表面裂纹与皮下裂纹缺陷得到了有效控制。同时,对浇注w（C）为0.090%-0.120%钢种时采用MB-59型保护渣连铸坯表面无裂纹的原因进行了探讨分析,认为由于选分结晶,优先凝固的坯壳中碳质量分数低于钢液原始碳质量分数,使优先凝固的坯壳中w（C）实际已经小于0.090%,不再属于裂纹敏感性强的包晶钢范围,因此表面质量较好。

关键词：包晶钢连铸保护渣表面纵裂

Contrasting habitat use and conservation status of Chinese-wintering and other Eurasian Greater White-fronted Goose(Anser albifrons)populations

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Avian Research 2021年第4期12卷 600-611页

作者： Xueqin Deng Qingshan Zhao Junjian Zhang Andrea Kölzsch Diana Solovyeva Inga Bysykatova-Harmey Zhenggang Xu Helmut Kruckenberg lei cao Anthony David Fox State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 101408China Department of Migration Max Planck Institute of Animal BehaviorRadolfzellGermany Institute for Wetlands and Waterbird Research E.V.(IWWR) Verden(Aller)Germany Institute of Biological Problems of the North MagadanRussia Institute of Biological Problems of Cryolitozone YakutskRussia Key Laboratory of National Forestry and Grassland Administration On Manage-ment of Western Forest Bio-Disaster College of ForestryNorthwest A&F Uni-versityYangling 712100China Department of Ecoscience Aarhus UniversityAarhusDenmark

Background:GPS/GSM tracking data were used to contrast use of(i)habitats and(ii)protected areas between three Arctic-nesting Greater White-fronted Geese(Anser albifrons,GWFG)populations throughout the annual *** wished to demonstrate that the East Asian Continental Population(which winters on natural wetlands in the Chinese Yangtze River floodplain and is currently declining)avoids using farmland at multiple wintering *** also gath-ered tracking evidence to support general observations from two increasing population of GWFG,the North Sea-Baltic(which winters in Europe)and the West Pacific(which winter in Korea and Japan)winter mostly within farmland landscapes,using wetlands only for safe night ***:We tracked 156 GWFG throughout their annual cycle using GPS/GSM transmitters from these three popu-lations to determine migration routes and stopover staging *** used Brownian Bridge Movement Models to generate summer,winter and migration stopover home ranges which we then overlaid in GIS with land cover and protected area boundary at national level to determine habitat use and degree of protection from nature conserva-tion designated ***:Data confirmed that 73%of European wintering GWFG homes ranges were from within farmland,com-pared to 59%in Japan and Korea,but just 5%in China,confirming the heavy winter use of agricultural landscapes by GWFG away from China,and avoidance of farmland at multiple sites within the Yangtze River *** same GWFG used farmland in northeast China in spring and autumn,confirming their experience of exploiting such habi-tats at other stages of their annual *** wintering birds showed the greatest overlap with protected areas of all three populations,showing current levels of site safeguard are failing to protect this ***:Results confirm the need for strategic planning to protect the East Asian Continental GWFG *** the site protection network in place to p

关键词： Farmland feeding Habitat use Migration National nature reserve Protected areas Staging areas

Microstructural evolution and thermal fatigue damage mechanism of second-phase dispersion strengthened tungsten composites under repetitive thermal loads

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Journal of Materials Science & Technology 2023年第9期140卷 221-232页

作者： Hui Wang Zhuoming Xie Xiang Cheng Ke Jing Linchao Zhang Junfeng Yang Rui Liu Le Han lei cao Xianping Wang Qianfeng Fang Changsong Liu Xuebang Wu Key Laboratory of Materials Physics Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China Institute of Plasma Physics Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China

In a fusion reactor,plasma-facing tungsten(W)materials inevitably suffer severe thermal shock,and the performance of W materials under repetitive high heat loads is one of the key concerns for long-term stable operation of the *** this work,the microstructural evolution and thermal fatigue resistance of two representative W-0.5 wt.%ZrC(WZC)and W-1.0 wt.% Y_(2)O_(3)(WYO)composites were investigated under cyclic heat *** to the intrinsic properties of ZrC and Y_(2)O_(3)particles such as coefficients of thermal expansion,particle size and distributions in W grains,the WZC composite exhibited a better thermal shock resistance than *** thermal loads with the absorbed power density(APD)≥22 MW/m^(2),WYO showed obvious grain growth,Y_(2)O_(3)particles shedding and degradation of mechanical ***,in the case of WZC,these damage behaviors only occurred when APD≥25 MW/m^(2).Furthermore,an interesting crack mechanism in W composites was revealed due to interface debonding and progressive shedding of second-phase particles from the W *** microstructures and tensile properties of the thermally loaded WZC and WYO specimens were also investigated and the correlations between the microstructure evolution and performance degradation are *** results are useful for evaluating the thermal fatigue resistance of oxide/carbide dispersion strengthened W composites and their application in future fusion reactors.

关键词： Tungsten Thermal loads Microstructure Particle shedding Mechanical properties

TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelope

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Protein & Cell 2015年第11期6卷 814-824页

作者： Shuai Yuan lei cao Hui Ling Minghao Dang Yao Sun Xuyuan Zhang Yutao Chen Liguo Zhang Dan Su Xiangxi Wang Zihe Rao National Laboratory of Macromolecules Institute of Biophysics Chinese Academy of Science Beijing 100101 China University of Chinese Academy of Sciences Beijing 100049 China State Key Laboratory of Biotherapy/Collaborative-lnnovation Center of Biotherapy West China Hospital Sichuan University Chengdu 610041 China College of Biotechnology Tianjin University of Science and Technology Tianjin 300457 China

Ebolavirus can cause hemorrhagic fever in humans with a mortality rate of 50%-90%. Currently, no approved vaccines and antiviral therapies are available. Human TIM1 is considered as an attachment factor for EBOV, enhancing viral infection through interaction with PS located on the viral envelope. However, reasons under- lying the preferable usage of hTIM-1, but not other PS binding receptors by filovirus, remain unknown. We firstly demonstrated a direct interaction between hTIM-1 and EBOV GP in vitro and determined the crystal structures of the Ig V domains of hTIM-1 and hTIM-4. The binding region in hTIM-1 to EBOV GP was mapped by chimeras and mutation assays, which were designed based on structural analysis. Pseudovirion infection assays performed using hTIM-1 and its homologs as well as point mutants verified the location of the GP binding site and the importance of EBOV GP-hTIM-1 interaction in EBOV cellular entry.

关键词： Ebolavirus viral entry glycoprotein,receptor interaction

Fluorine-doped carbon quantum dots with deep-red emission for hypochlorite determination and cancer cell imaging

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Chinese Chemical Letters 2024年第6期35卷 433-438页

作者： Boran Cheng lei cao Chen Li Fang-Yi Huo Qian-Fang Meng Ganglin Tong Xuan Wu Lin-Lin Bu Lang Rao Shubin Wang Department of Oncology Shenzhen Key Laboratory of Gastrointestinal Cancer Translational ResearchCancer InstitutePeking University Shenzhen HospitalShenzhen-Peking University-Hong Kong University of Science and Technology Medical CenterShenzhen 518036China Institute of Biomedical Health Technology and Engineering Shenzhen Bay LaboratoryShenzhen 518132China The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)&Key Laboratory of Oral Biomedicine Ministry of Education School&Hospital of StomatologyWuhan UniversityWuhan 430079China

As a type of new carbon-based nanomaterials,carbon dots(CDs)possess exceptional optical properties,making them highly desirable for use in fluorescent ***,the CDs with deep-red(DR)or near-infrared(NIR)emission have rarely been *** this work,we prepared deep-red emissive fluorine-doped carbon quantum dots(F-CDs)by introducing a precursor simultaneously containing fluorine and *** synergistic effect of nitrogen doping and D-π-A pattern production contributed to the maximum emission of F-CDs at 636 nm with an absolute quantum yield of 36.00%±0.68%.Moreover,we designed an F-CDs-based fluorescence assay to determine the content of hypochlorite(ClO^(-)),with a limit of detection(LOD)as low as 15.4 nmol/L,indicating the high sensitivity of F-CDs to ClO^(-).In real samples,the F-CDs-based fluorescent sensor exhibited excellent sensitivity and selectivity in the detection of ClO^(-),with an error below 2%,suggesting their great potential in daily *** cancer cell imaging,the F-CDs not only demonstrated high sensitivity to ClO^(-)but also exhibited excellent mitochondria targeting,as evidenced by the high Pearson's correlation coefficient(PCC)of 0.93 in colocalization *** work presented here suggests the great potential of replacing commercial dyes with F-CDs for highly specific mitochondria labeling and cell imaging.

关键词： Carbon dots Near-infrared Cell imaging Mitochondria labeling Hypochlorite determination