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Explicit Reciprocity Law for Lubin-Tate Formal Groups

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Acta Mathematica Sinica,English Series 2006年第5期22卷 1399-1412页

作者： lei cao School of Mathematical Sciences Peking University Beijing 100871 P. R. China

In this article, using Fontaine＇s ФГ-module theory, we give a new proof of Coleman＇s explicit reciprocity law, which generalizes that of Artin-Hasse, Iwasawa and Wiles, by giving a complete formula for the norm residue symbol on Lubin-Tate groups. The method used here is different from the classical ones and can be used to study the Iwasawa theory of crystalline representations.

关键词： ФГ-module Formal groups explicit reciprocity law Kummer map

Hybrid graded element model for transient heat conduction in functionally graded materials

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Acta Mechanica Sinica 2012年第1期28卷 128-139页

作者： lei-lei cao Qing-Hua Qin Ning Zhao Key Laboratory for Road Construction Technology＆ Equipment of MOE Chang＇ an University 710064 Xi＇ an China Research School of Engineering Australian National UniversityCanberra ACT 0200 Australia School of Mechatronics Northwestern Polytechnical University710072 Xi＇an China

This paper presents a hybrid graded element model for the transient heat conduction problem in functionally graded materials （FGMs）. First, a Laplace transform approach is used to handle the time variable. Then, a fundamental solution in Laplace space for FGMs is constructed. Next, a hybrid graded element is formulated based on the obtained fundamental solution and a frame field. As a result, the graded properties of FGMs are naturally reflected by using the fundamental solution to interpolate the intra-element field. Further, Stefest＇s algorithm is employed to convert the results in Laplace space back into the time-space domain. Finally, the performance of the proposed method is assessed by several benchmark examples. The results demonstrate well the efficiency and accuracy of the proposed method.

关键词： Graded element model Functionally graded materials Hybrid FEM Transient heat conduction

A Novel Method for Type Synthesis of Parallel Mechanism Without Parasitic Motion Based on 2R1T Parallel Mechanism with Rotational Bifurcation

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Chinese Journal of Mechanical Engineering 2022年第4期35卷 191-202页

作者： Jinghan Qin Chunzhan Yu Zhibo Sun lei cao School of Technology Beijing Forestry UniversityBeijing 100083China Engineering Training Center Beihang UniversityBeijing 102206China Capital Aerospace Machinery Co.Ltd Beijing 100621China

The parasitic motion has been widely recognized as the major drawback of the parallel *** a class of 2R1T PMs(parallel mechanism)without parasitic motion has been ***,these PMs can only rotate around two axes in sequential *** decreases the performance of the balancing adjustment of the *** this paper,a family of 2R1T PMs without parasitic motion was reconstructed by using a novel method based on the remarkable properties of rotational bifurcation mechanisms,which can rotate in sequential ***,some PMs rotating around two continuous axes in an arbitrary order are established by adding single *** the practicability of these structures into consideration,the workspace of 3-PRPS PM was analyzed as an ***,this study explores the practical application of the PMs without parasitic motion in developing balance mechanisms in rough-terrain fre-fghting *** the climbing process,the tank is adjusted to be parallel to the horizontal plane in *** is proved that this kind of structure realizes continuous rotation around two rotation axes on the premise of no parasitic motion.

关键词： Parallel mechanism Rotational bifurcation Parasitic motion Type synthesis Balance mechanism

Research status of inclusions in bearing steel and discussion on non-alloy deoxidation process

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Journal of Iron and Steel Research International 2023年第1期30卷 1-20页

作者： lei cao Li-guang Zhu Zhi-hong Guo School of Metallurgy and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Materials Engineering Department Hebei Vocational University of Industry and TechnologyShijiazhuang 050091HebeiChina Department of Materials Science and Engineering Hebei University of Science and TechnologyShijiazhuang 050090HebeiChina

Non-metallic inclusion in steel is a very key factor affecting the fatigue life and quality stability of high-quality bearing *** mainly affect the fatigue life and toughness of the material by affecting the continuity of the steel matrix,thereby endangering the safety and stability of the *** research progress of inclusion formation,removal and modification was *** on the current research status of Al deoxidation or Si deoxidation process,the feasibility of non-alloy deoxidation process for high-quality bearing steel was proposed and discussed.C or H_(2) is used as non-alloy deoxidizer,and the deoxidation products are CO and H_(2)O gases,which are easy to be removed from the molten *** are few studies on the non-alloy deoxidation process,especially the research and application of C or H_(2) deoxidation for high-quality bearing ***,the non-alloy deoxidation process is of great significance for reducing oxygen content and improving cleanliness of high-quality bearing ***,it is necessary to study the mechanism and kinetics of C and H_(2) deoxidation and analyze the factors affecting deoxidation effect systematically,so as to provide a solid theoretical basis for the practice of non-alloy deoxidation process for high-quality bearing steel.

关键词： High-quality bearing steel Non-metallic inclusion Non-alloy deoxidation C deoxidation H_(2)deoxidation

Advances in non-invasive imaging of proteinopathies in animal models of neurodegenerative diseases

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Neural Regeneration Research 2024年第10期19卷 2115-2116页

作者： lei cao Bin Ji Ruiqing Ni Changes Technology Corporation Ltd. ShanghaiChina Fudan University ShanghaiChina School of Pharmacy Fudan UniversityShanghaiChina Institute for Biomedical Engineering University of Zurich&ETH Zurich Institute for Regenerative MedicineUniversity of ZurichZurichSwitzerland

Neurodegenerative diseases,including Alzheimer's disease(AD),frontotemporal dementia,Parkinson's disease,and dementia with Lewy bodies,represent tremendous unmet clinical needs.A common feature of these diseases is the aberrant cerebral accumulation of pathological protein aggregates,affecting selectively vulnerable circuits in a disease-specific *** studies have established a relationship between abnormal aggregation and neuronal dysfunction or loss,suggesting multifactorial pathogenesis mechanisms in these neurodegenerative disorders.

关键词： diseases degenerative clinical

Modified joint probabilistic data association with classification-aided for multitarget tracking

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Journal of Systems Engineering and Electronics 2008年第3期19卷 434-439页

作者： Ba Hongxin cao lei He Xinyi Cheng Qun Air Force Command Coll. Beijing 100097 P. R. China Inst. of Command Automation PLA Univ. of Science & Technology Nanjing 210007 P. R. China Inst. of Combat Systems Naval Academy of Armament Beijing 100073 P. R. China Scientific Research Dept. PLA Univ. of Science & Technology Nanjing 210007 P. R. China

Joint probabilistic data association is an effective method for tracking multiple targets in clutter, but only the target kinematic information is used in measure-to-track association. If the kinematic likelihoods are similar for different closely spaced targets, there is ambiguity in using the kinematic information alone; the correct association probability will decrease in conventional joint probabilistic data association algorithm and track coalescence will occur easily. A modified algorithm of joint probabilistic data association with classification-aided is presented, which avoids track coalescence when tracking multiple neighboring targets. Firstly, an identification matrix is defined, which is used to simplify validation matrix to decrease computational complexity. Then, target class information is integrated into the data association process. Performance comparisons with and without the use of class information in JPDA are presented on multiple closely spaced maneuvering targets tracking problem. Simulation results quantify the benefits of classification-aided JPDA for improved multiple targets tracking, especially in the presence of association uncertainty in the kinematic measurement and target maneuvering. Simulation results indicate that the algorithm is valid.

关键词： multi-target tracking data association joint probabilistic data association classification information,track coalescence maneuvering target.

Rational design of hollow oxygen deficiency-enriched NiFe_(2)O_(4)@N/rGO as bifunctional electrocatalysts for overall water splitting

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Journal of Energy Chemistry 2021年第3期30卷 595-603页

作者： lei cao Zhenhuan Li Kunmei Su Maliang Zhang Bowen Cheng State Key Laboratory of Separation Membranes and Membrane Processes/National Center for International Joint Research on Separation Membranes School of Materials Science and EngineeringTiangong UniversityTianjin 300387China School of Environment Science and Chemistry Engineering Tiangong UniversityTianjin 300160China

Bimetallic metal organic framework(MOF)as a precursor to prepare catalysts with bifunctional catalytic activity of oxygen evolution reaction(OER)and hydrogen evolution reaction(HER)attracts more and more ***,hollow oxygen deficiency-enriched NiFe_(2)O_(4) is synthesized by pyrolytic FeNi bimetallic *** defects of rGO during carbonization can act as nucleation sites for FeNi *** nucleation and N doping,the FeNi particles were served as catalysts for the deposition of dissolved carbon in the defects of the N/*** deposited carbon,like a bridge,connect N/rGO and hollow oxygen deficiency-enriched NiFe_(2)O_(4) together,which giving full play to the advantages of N/rGO in fast electron transfer,thereby improving its catalytic *** resultant NiFe_(2)O_(4)@N/rGO-800 exhibits a low overpotential of 252 mV at 20 mA cm^(-2) for OER and 157 mV at 10 mA cm^(-2) for HER in 1 M KOH,*** used as bifunctional electrodes for overall water splitting,it also shows low cell voltage of 1.60 V and 1.67 V at 10 and 20 mA cm^(-2),respectively.

关键词： Oxygen deficiency Hollow NiFe_(2)O_(4) N/rGO Bifunctional electrocatalyst Overall water splitting

Phase Ⅰ study of ***19 chimeric antigen receptor T cell in the treatment of refractory diffuse large B-cell lymphoma in Chinese patients

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Frontiers of Medicine 2022年第2期16卷 285-294,F0004页

作者： lei Fan Li Wang lei cao Huayuan Zhu Wei Xu Jianyong Li Department of Hematology Pukou CLL CenterJiangsu Province HospitalThe First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China

Anti-CD 19 chimeric antigen receptor(CAR)T cell therapy has shown impressive efficacy in treating B-cell malignancies.A single-center phase I dose-escalation study was conducted to evaluate the safety and efficacy of T cells transduced with ***19 CAR,a second-generation anti-CD19 CAR bearing 4-1BB costimulatory molecule,for the treatment of patients with refractory diffuse large B-cell lymphoma(DLBCL).Ten heavily treated patients with refractory DLBCL were given ***19 CAR-T cell(C-CAR011)*** overall response rate was 20%and 50%at 4 and 12 weeks after the infusion of C-CAR011,respectively,and the disease control rate was 60%at 12 weeks after ***-emergent adverse events occurred in all *** incidence of cytokine release syndrome in all grades and grade^3 was 90%and 0,respectively,which is consistent with the safety profile of axicabtagene ciloleucel and *** or other dose-limiting toxicides was not observed in any dose cohort of C-CAR011 *** efficacy was apparent across dose ***,C-CAR011 is a safe and effective therapeutic option for Chinese patients with refractory DLBCL,and further large-scale clinical trials are warranted.

关键词： CAR-T cell therapy refractory diffuse large B-cell lymphoma cytokine release syndrome dose-limiting toxicity

Methane absorption and application of mixed organic aggregate prepared from Span80 and alkaline salt

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Science China(Technological Sciences) 2009年第8期52卷 2155-2160页

作者： ZHANG ZengZhi GU Na cao lei SHU XinQian State Key Laboratory of Coal Resources and Mine Safety China University of Mining and TechnologyBeijing 100083China Research Institute of Ecological and Functional Materials China University of Mining and TechnologyBeijing 100083China School of Chemical and Environmental Engineering China University of Mining and TechnologyBeijing 100083China

The water-based materials for mine gas absorption and explosion suppression were prepared, in which the mixed organic aggregate of Span80 and alkaline salt can be used as methane absorbent. Methane was used as a model of mine gas, and the absorptions of methane with different complex materials were studied using head space gas chromatography. Then the state of aqueous material was characterized with laser light scattering instrument and the effects of different complex materials on explosion suppression were preliminarily studied in explosion chamber which can simulate mine gas explosion. The research results showed that complex material could absorb methane and there was some corre- lation between the mean diameter of organic aggregate in aqueous material and the absorption effect. Additionally, the aqueous material could suppress the methane explosion to some degree. The material can absorb mine gas in atomization condition, therefore, degrease mine gas concentration and influence the distribution of mine gas in the space, and then suppress the mine gas explosion to some extent.

关键词： sorbitan monooleate alkaline salt organic aggregate methane absorption mine gas explosion suppression