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区间直觉模糊事件概率及其泛化形式的研究

系统工程与电子技术 2011年第2期33卷 350-355页

作者：樊雷雷英杰空军工程大学导弹学院陕西三原713800

针对随机现象中存在的模糊性,给出了区间直觉模糊集(interval-valued intuitionistic fuzzy sets,IVIFS)的解决方案。首先,定义了样本空间中区间直觉模糊事件(interval-valued intuitionistic fuzzy events,IVIFE)的概念,给出了区间直觉模糊事件概率的描述化定义。其次,定义了区间直觉模糊三角模及三角余模的概念,给出了区间直觉模糊事件概率的公理化定义。再次,给出了区间直觉模糊概率的泛化形式,即可分形式和不可分形式,并详细证明了不可分形式。最后,通过实例验证了不可分形式。

关键词：区间直觉模糊集区间直觉模糊事件区间直觉模糊事件概率

GSTAR:an innovative software platform for processing space geodetic data at the observation level

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Satellite Navigation 2023年第3期4卷 122-141页

作者： Chuang Shi Shiwei Guo lei fan Shengfeng Gu Xinqi fang Linghao Zhou Tao Zhang Zhen Li Min Li Wenwen Li Cheng Wang Yidong Lou Key Laboratory of Navigation and Communication Fusion Technology Ministry of Industry and Information Technology37 Xueyuan RoadBeijing 100191China School of Electronic and Information Engineering Beihang University37 Xueyuan RoadBeijing 100191China Research Institute for Frontier Science Beihang University37 Xueyuan RoadBeijing 100191China GNSS Research Center Wuhan University129 Luoyu RoadWuhan 430079China

To meet the demands for the data combination with multiple space geodetic techniques at the observation level,we developed a new software platform with high extensibility and computation efficiency,named space Geodetic SpatioTemporal data Analysis and Research software(GSTAR).Most of the modules in the GSTAR are coded in C++with object-oriented *** layered modular theory is adopted for the design of the software,and the antenna-based data architecture is proposed for users to construct personalized geodetic application scenarios *** initial performance of the GSTAR software is evaluated by processing the Global Navigation Satellite System(GNSS)data collected from 315 globally distributed stations over two and a half *** accuracy of GNSS-based geodetic products is evaluated by comparing them with those released by International GNSS Service(IGS)Analysis Centers(AC).Taking the products released by European Space Agency(ESA)as reference,the Three-Dimension(3D)Root-Mean-Squares(RMS)of the orbit differences are 2.7/6.7/3.3/7.7/21.0 cm and the STandard Deviations(STD)of the clock differences are 19/48/16/32/25 ps for Global Positioning System(GPS),GLObal NAvigation Satellite System(GLONASS),Galileo navigation satellite system(Galileo),BeiDou Navigation Satellite System(BDS),Medium Earth Orbit(MEO),and BDS Inclined Geo-Synchronous Orbit(IGSO)satellites,*** mean values of the X and Y components of the polar coordinate and the Length of Day(LOD)with respect to the International Earth Rotation and Reference Systems Service(IERS)14 C04 products are-17.6 microarc-second(μas),9.2μas,and 14.0μs/*** to the IGS daily solution,the RMSs of the site position differences in the north/east/up direction are 1.6/1.5/3.9,3.8/2.4/7.6,2.5/2.4/7.9 and 2.7/2.3/7.4 mm for GPS-only,GLONASS-only,Galileo-only,and BDS-only solution,*** RMSs of the differences of the tropospheric Zenith Path Delay(ZPD),the north gradients,and the east gradien

关键词： GSTAR GNSS BDS LEO Precise orbit determination Precise clock estimation Earth rotation parameter Tropospheric zenith path delay Geocenter motion Rapid data processing

The Effect of Graphene Oxide on Mechanical Properties of Cement Mortar

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Research and Application of Materials Science 2024年第1期6卷 1-4页

作者： lei fan Jinhao ZHENG School of Civil Engineering and Architecture Zhejiang University of Science&TechnologyHangzhouZhejiang310023China Zhejiang-Singapore Joint Laboratory for Urban Renewal and Future City HangzhouZhejiang310023China

Cement is widely used in engineering applications,but it has both the characteristics of high brittleness and poor bending *** this paper,the effects of different amounts ofgraphene oxide on the flexural strength and compressive strength of cement mortar were studied by doping a certain amount of graphene oxide with cement mortar,and the strengthening mechanism of graphene oxide on cement mortar was obtained through microstructure *** is found that graphene oxide has a significant enhancement effect on the macroscopic mechanical properties of cement mortar,and graphene oxide provides nano-nucleation sites and growth templates for cement mortar,accelerates the hydration process,reduces the voids between hydration products,greatly increases the compactness,and improves the macroscopic properties of cement-based materials.

关键词： Graphene oxide Cement mortar Mechanical properties Microscopic analysis

Study on Multi-Scale Tensile Strength and Tensile Strain of Calcium Silicate Hydrate Layered Nanocomposites Under External Physical Field

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Research and Application of Materials Science 2023年第1期5卷 1-4页

作者： lei fan Lele ZHANG School of Civil and Architectural Engineering Zhejiang University of Science and Technology Hangzhou 31002 P.R.China

Calcium silicate hydrate(C-S-H)is the mainly strength source of cement-based materials,but there is little basic *** this paper,molecular dynamics method is applied to analyze the multi-scale tensile strength and tensile strain of C-S-H layered materials under the condition of external physical fields(temperature and strain rate).The results show that the tensile strength and strain of C-S-H model decrease with temperature *** temperature(from 1 K to 600 K)has obvious influence on the tensile strain and strength of C-S-H layered *** addition,at(0.00025 ps^(-1)-0.001 ps^(-1)),the tensile strain and strength of C-S-H layered materials are less sensitive to strain *** whole model is closer to a 3-dimensional ***,at(0.001 ps^(-1)-0.005 ps^(-1)),the dynamic load effect begins to increase,and the work done by the load per unit time *** tensile strain and strength of C-S-H layered materials indicates intensified by the change of strain *** energies are randomly distributed in the system,not concentrated in a certain area.

关键词： Hydrated calcium silicate External physical field Multiscale Mechanical properties Molecular dynamics

Reproductive toxicity of brazilein in ICR mice

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Chinese Journal of Natural Medicines 2016年第6期14卷 441-448页

作者： YUAN Zhi-Yi lei fan CHAI Yu-Shuang WU Hao ZHAO Shuang WANG Yu-Gang FENG Tian-Shi LI Hui-Ying LI Hui-Yu ZHAN Hong-lei XING Dong-Ming DU Li-Jun MOE Key Laboratory of Protein Sciences Laboratory of Molecular Pharmacology and Pharmaceutical Sciences School of Life Sciences and School of Medicine Tsinghua University NGM Biopharmaceuticals Inc.

Brazilein is an active small molecular compound extracted from Caesalpinia sappan L. with favorable pharmacological properties on immune system, cardiovascular system, and nervous system. C. sappan has been used as a traditional medicine in China for hundreds of years for various diseases. However, the general reproductive toxicity of brazilein is still unknown. The purpose of the present study was to thoroughly evaluate the general reproductive toxicity of brazilein in ICR mice to support the future drug development and modernization of this potent traditional Chinese medicine. The results showed that, although no apparent toxicity on the reproducibility of the male was observed, brazilein might cause considerable risks to the fetuses and females as indicated by the ratios of dead fetuses and reabsorptions. In conclusion, our results from the present study provided some useful insights about the safety profile of brazilein, suggesting that brazilein should be used with caution in pregnant women.

关键词： Brazilein General productive toxicity Mice

Anti-nociceptive Effect of Patchouli Alcohol: Involving Attenuation of Cyclooxygenase 2 and Modulation of Mu-Opioid Receptor

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Chinese Journal of Integrative Medicine 2019年第6期25卷 454-461页

作者： YU Xuan WANG Xin-pei YAN Xiao-jin JIANG Jing-fei lei fan XING Dong-ming GUO Yue-ying DU Li-jun MOE Key Laboratory of Protein Sciences Laboratory of Molecular Pharmacology and Pharmaceutical Sciences School of Life Sciences Tsinghua University Beijing (100084) China School of Pharmacology and Pharmaceutical Sciences Tsinghua University Beijing (100084) China

Objective: To explore the anti-nociceptive effect of patchouli alcohol(PA), the essential oil isolated from Pogostemon cablin(Blanco) Bent, and determine the mechanism in molecular levels. Methods: The acetic acid-induced writhing test and formalin-induced plantar injection test in mice were employed to con?rm the effect in vivo. Intracellular calcium ion was imaged to verify PA on mu-opioid receptor(MOR). Cyclooxygenase 2(COX2)and MOR of mouse brain were expressed for determination of PA’s target. Cellular experiments were carried out to find out COX2 and MOR expression induced by PA. Results: PA significantly reduced latency period of visceral pain and writhing induced by acetic acid saline solution(P<0.01) and allodynia after intra-plantar formalin(P<0.01) in mice. PA also up-regulated COX2 mRNA and protein(P<0.05) with a down-regulation of MOR(P<0.05) both in in vivo and in vitro experiments, which devote to the analgesic effect of PA. A decrease in the intracellular calcium level(P<0.05) induced by PA may play an important role in its anti-nociceptive *** showed the characters of enhancing the MOR expression and reducing the intracellular calcium ion similar to opioid effect. Conclusions: Both COX2 and MOR are involved in the mechanism of PA’s anti-nociceptive effect,and the up-regulation of the receptor expression and the inhibition of intracellular calcium are a new perspective to PA’s effect on MOR.

关键词： Chinese medici ne patchouli alcohol an algesic effect mu-opioid receptor cyclooxyge nase 2

Triple-functional bone adhesive with enhanced internal fixation,bacteriostasis and osteoinductive properties for open fracture repair

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Bioactive Materials 2023年第7期25卷 273-290页

作者： Yusheng Yang Shenghui Su Shencai Liu Weilu Liu Qinfeng Yang Liangjie Tian Zilin Tan lei fan Bin Yu Jian Wang Yanjun Hu Division of Orthopaedics and Traumatology Department of OrthopaedicsNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong Province510515China Department of Orthopaedics Ningde Municipal HospitalNingde Normal UniversityNingdeFujian Province352100China Division of Orthopaedics Surgery Department of OrthopaedicsNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong Province510515China Department of General Surgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong Province510515China

At present,effective fixation and anti-infection implant materials represent the mainstay for the treatment of open ***,external fixation can cause nail tract infections and is ineffective for fixing small fracture ***,closed reduction and internal fixation during the early stage of injury can lead to potential bone infection,conducive to bone nonunion and delayed ***,we designed a bone adhesive with anti-infection,osteogenic and bone adhesion fixation properties to promote reduction and fixation of open fractures and subsequent soft tissue *** was prepared by the reaction of gelatin(Gel)and oxidized starch(OS)with vancomycin(VAN)-loaded mesoporous bioactive glass nanoparticles(MBGNs)covalently cross-linked with Schiff *** and adhesion experiments were conducted to validate the successful preparation of the Gel-OS/VAN@MBGNs(GOVM-gel)***,in vitro cell experiments demonstrated its good antibacterial effects with the ability to stimulate bone marrow mesenchymal stem cell(BMSCs)proliferation,upregulate the expression of alkaline phosphatase(ALP)and osteogenic proteins(RunX2 and OPN)and enhance the deposition of calcium ***,we established a rat skull fracture model and a subcutaneous infection *** histological analysis showed that bone adhesive enhanced osteogenesis,and in vivo experiments demonstrated that the number of inflammatory cells and bacteria was significantly ***,the adhesive could promote early reduction of fractures and antibacterial and osteogenic effects,providing the foothold for treatment of this patient population.

关键词： Open fracture Bone adhesive Internal fixation Bacteriostasis Osteoinduction

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二次电压控制研究(二)

电力系统自动化 2000年第12期24卷 20-24页

作者：范磊陈珩国家电力公司电力自动化研究院南京210003 东南大学电气工程系南京210096

研究了一种新的提高系统电压稳定性的方法——二次电压控制。利用二次电压控制结构化模型推导了选择主导节点的优化目标 ,讨论了遗传算法在主导节点选择中的应用。建立了二次电压控制系统相应的二次性能指标 ,确定了具体的二次电压控制... 详细信息

研究了一种新的提高系统电压稳定性的方法——二次电压控制。利用二次电压控制结构化模型推导了选择主导节点的优化目标 ,讨论了遗传算法在主导节点选择中的应用。建立了二次电压控制系统相应的二次性能指标 ,确定了具体的二次电压控制策略。

关键词：二次电压控制电压稳定控制策略电力系统

Operational Semantic of Workflow Engine and the Realizing Technique

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The Journal of China Universities of Posts and Telecommunications 2005年第4期12卷 17-20,47页

作者： FU Yan-ning LIU lei ZHAO Dong-fan JIN Long-fei College of Computer Science and Technology Jilin University Changchun 130012 P.R. China

At present, there is no formalized description of the executing procedure of workflow models. The procedure of workflow models executing in workflow engine is described using operational semantic. The formalized description of process instances and activity instances leads to very clear structure of the workflow engine, has easy cooperation of the heterogeneous workflow engines and guides the realization of the workflow engine function. Meanwhile, the software of work flow engine has been completed by means of the formalized description.

关键词： workflow engine process model process instance activity instance operational semantic