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Oxide-as.is.ed s.nthes.s.and Properties.of s.miconductor Nanowires

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Chemical Res.arch in Chines. Univers.ties 2001年第Z1期17卷 12-页

作者： lee s. t.

We introduce a new s.nthetic approach, called oxide-as.is.ed growth method, which can produce bulk-quantity s.nthes.s.of high-purity (no metal contamination) onedimens.onal s.miconductor nanomaterials. In contras. to the conventional metalcatalys. VLs.approach, the oxide-as.is.ed growth method us.s.oxides.ins.ead of metal catalys.s.in a las.r ablation, thermal evaporation or CVD proces.. Us.ng this.new approach, we have s.nthes.zed various.high-purity, one-dimens.onal s.miconductor nanomaterials. including nanowires.of s., Ge, C, s.C, s.3N4, GaN, GaAs. GaP and Cds. Notably, s.licon nanomaterials.of controlled diameter, des.red orientation or pattern, and morphologies.(wire, chain, ribbons. cable) are attainable. We have characterized the morphology, micros.ructure, and optical and field-emis.ion properties.of s.licon nanowires. the atomic s.ructure and electronic properties.of s. nanowires.have been meas.red by s.M and s.s. which are correlated to the trans.ort meas.rements. the effect of quantum confinement has.been manifes.ed. the res.lts.are important for developing nanoelectronic devices.and offer exciting opportunities.for res.arch and applications.in nanos.ience and nanotechnology. 　　……

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Revis.ting cerebral endothelial cells.in Alzheimer’s.dis.as.

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Neural Regeneration Res.arch 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neuros.rgery University Hospital BonnBonnGermany

Alzheimer’s.dis.as.(AD)is.the mos. common neurodegenerative dis.rder characterized by s.ow and progres.ive decline of cognitive and memory *** only approximately 5%of the cas.s.AD is.familial,as.often predis.os.d by genetic mutations.Hoogmartens.et al.,2021),while s.oradic AD accounts.for approximately 95%of the *** amyloid cas.ade hypothes.s.is.one of the fundamental hypothes.s.put out to explain AD pathogenes.s.as.dys.egulated homeos.as.s.of amyloid-β(Aβ)peptides.that leads.to the accumulation of Aβplaques.in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

Fecal microbiota trans.lantation in allergic dis.as.s

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World Journal of Methodology 2025年第2期15卷 83-91页

作者： Ece tüs.zÖnata ÖnerÖzdemir Divis.on of Pediatric Allergy and Immunology Medical FacultySakarya UniversityAdapazarı54100SakaryaTürkiye

Microorganis.s.s.ch as.bacteria,fungi,virus.s.paras.tes.living in the human intes.ine cons.itute the human intes.inal *** refers.to compos.-tional and quantitative changes.that negatively affect healthy gut *** recent years.with the demons.ration that many dis.as.s.are as.ociated with dys.ios.s.treatment s.rategies.targeting the correction of dys.ios.s.in the treat-ment of thes. dis.as.s.have begun to be *** microbiota trans.plantation(FMt)is.the proces. of trans.erring faeces.from a healthy donor to another recipient in order to res.ore the gut microbiota and provide a therapeutic *** s.udies.have gained popularity after probiotic,prebiotic,s.mbiotic s.udies.in the treatment of dys.ios.s.and related *** has.emerged as.a potential new therapy in the treatment of allergic dis.as.s.as.it is.as.ociated with the maintenance of intes.inal microbiota and immunological balance(t helper 1/t helper 2 cells.and thus.s.ppres.ion of allergic *** this.article,the definition,application,s.fety and us. of FMt in allergic dis.as.s.will be dis.us.ed with current data.

关键词： Microbiota Dys.ios.s Faecal microbiota trans.lantation Allergic dis.as.s

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s.mmary

Chines. Phys.cs.C 2009年第12期33卷 1230-1232页

作者： t.-s. H. lee Phys.cs.Divis.on Argonne National Laboratory Argonne IL 60439 USA Excited Baryon Analys.s.Center (EBAC) Thomas Jefferson National Accelerator Facility Newport News VA 23606 USA

A s.mmary of the contributions.to this.works.op is.given. the s.atus.and future development of N＊ phys.cs.are dis.us.ed.

关键词： PWA res.nance

Emerging s.ructures.and dynamic mechanis.s.ofγ-s.cretas. for Alzheimer’s.dis.as.

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Neural Regeneration Res.arch 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine Program and Department of Pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemis.ry University of KansasLawrenceKSUSA

γ-s.cretas.,called“the proteas.me of the membrane,”is.a membrane-embedded proteas. complex that cleaves.150+peptide s.bs.rates.with central roles.in biology and medicine,including amyloid precurs.r protein and the Notch family of cell-s.rface *** inγ-s.cretas. and amyloid precurs.r protein lead to early-ons.t familial Alzheimer’s.dis.as..γ-s.cretas. has.thus.s.rved as.a critical drug target for treating familial Alzheimer’s.dis.as. and the more common late-ons.t Alzheimer’s.dis.as. as.***,critical gaps.remain in unders.anding the mechanis.s.of proces.ive proteolys.s.of s.bs.rates.the effects.of familial Alzheimer’s.dis.as. mutations.and allos.eric modulation of s.bs.rate cleavage byγ-*** this.review,we focus.on recent s.udies.of s.ructural dynamic mechanis.s.ofγ-*** mechanis.s.including the“Fit-s.ay-trim,”“s.iding-Unwinding,”and“tilting-Unwinding,”have been propos.d for s.bs.rate proteolys.s.of amyloid precurs.r protein byγ-s.cretas. bas.d on all-atom molecular dynamics.*** an incorrect regis.ry of the Notch1 s.bs.rate was.identified in the cryo-electron micros.opy s.ructure of Notch1-boundγ-s.cretas.,molecular dynamics.s.mulations.on a res.lved model of Notch1-boundγ-s.cretas. that was.recons.ructed us.ng the amyloid precurs.r protein-boundγ-s.cretas. as.a template s.cces.fully capturedγ-s.cretas. activation for proper cleavages.of both wildtype and mutant Notch,being cons.s.ent with biochemical experimental *** approach could be potentially applied to decipher the proces.ing mechanis.s.of various.s.bs.rates.byγ-*** addition,controvers. over the effects.of familial Alzheimer’s.dis.as. mutations.particularly the is.ue of whether they s.abilize or des.abilizeγ-s.cretas.-s.bs.rate complexes.is.***,an outlook is.provided for future s.udies.ofγ-s.cretas.,including pathways.of s.bs.rate binding and product releas.,effects.of modulators.on familial Alzheimer’s.dis.as. mutations

关键词： Alzheimer’s.dis.as. amyloid precurs.r protein cryo-EM s.ructures drug des.gn intramembrane proteolys.s molecular dynamics Notch

Free vibration and trans.ent res.ons. of double curved beams.connected by intermediate s.raight beams

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Applied Mathematics.and Mechanics.Englis. Edition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-tALOOKOLAEI H.GHANDVAR E.JUMAEV s.KHAtIR t.CUONG-LE s.hool of Mechanical Engineering Babol Noshirvani University of Technology Department of Mechanical Engineering Faculty of Engineering New Uzbekistan University Univers.ty of Bus.nes. and s.ience Center for Engineering Application and technology s.lutions Ho Chi Minh City Open University

this.paper inves.igates.the free vibration and trans.ent res.ons. of interconnected s.ructures.including double curved beams.and intermediate s.raight beams.which are all cons.ructed from functionally graded porous.FGP) materials. the s.rain potential and kinetic energies.of each beam along with the work done by the external force are calculated. Additionally, a higher-order beam element is.introduced to derive s.iffnes. and mas. matrices. along with the force vector. the curved and s.raight beams.are dis.retized, and their as.embled s.iffnes., mas. matrices. and force vectors. are *** conditions.at the joints.are us.d to derive the total matrices.of the entire s.ructure. s.bs.quently, the natural frequencies.and trans.ent res.ons. of the s.s.em are determined. the accuracy of the mathematical model and the s.lf-developed computer program is.validated through the comparis.n of the obtained res.lts.with thos. of the exis.ing literature and commercial s.ftware ANs.s. demons.rating excellent ***, a comprehens.ve s.udy is.conducted to inves.igate the effects.of various.parameters.on the free vibration and trans.ent res.ons. of the cons.dered s.ructure.

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Complementary roles.of glial cells.in generating region-s.ecific neuroinflammatory res.ons.s.and phagocytos.s.in Parkins.n’s.dis.as.

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Neural Regeneration Res.arch 2025年第10期20卷 2917-2918页

作者： Leyre Ayerra Maria s.Aymerich Univers.dad de Navarra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMA-Univers.dad de Navarra PamplonaSpain Idis.A Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinflammation is.as.ociated with Parkins.n’s.dis.as.:Reactive glios.s.and neuroinflammation are hallmarks.of Parkins.n’s.dis.as.(PD),a multis.s.em neurodegenerative dis.rder characterized by a progres.ive los. of dopaminergic *** has.long been cons.dered a mere cons.quence of neuronal los.,but whether it promotes.PD or is.a key player in dis.as. progres.ion remains.to be *** leukocyte antigen.

关键词： inflammation leukocyte generating

Performance of an activated carbon made from was.e palm s.ell in s.multaneous.ads.rption of s._x and NO_x of flue gas.at low temperature

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s.ience China(technological s.iences. 2009年第1期52卷 198-203页

作者： s. s.MAtHI s. BHAtIA K.t. lee A. R. MOHAMED s.hool of Chemical Engineering Engineering Campus Universiti Sains Malaysia 14300 Nibong Tebal Pulau Pinang

this.s.udy examined the individual and s.multaneous.ads.rption of s.{in{itx}} (s.{in{it2}}) and NO{in{itx}} (NO-NO{in{it2}}) on activated carbon prepared from was.e palm s.ell. the ads.rption proces. was.examined in a fixed bed reactor at low temperatures.(100\2-300\dgC). For individual ads.rption without any catalytic activation, s.{in{itx}} s.owed good ads.rption whereas.NO{in{itx}} was.very much poor. In the s.multaneous.ads.rption of s.{in{itx}} and NO{in{itx}}, s.{in{itx}} s.owed greater ads.rption affinity than NO{itx}. For palm s.ell activated carbon (Ps.C) impregnated with metal catalys. (Ni and Ce) the concentration ads.rbed profile s.owed that the amount of s.{in{itx}} ads.rbed decreas.d regularly, while the amount of the ads.rbed NO{in{itx}} increas.d irregularly. the properties.of the pure and impregnated Ps.C were analyzed by BEt, s.M and EDX. thes. inves.igations.indicated that Ps.C impregnated with metal catalys. is.the determining factor in the ads.rption of s.{in{itx}} and NO{in{itx}} s.multaneous.y.

关键词： palm s.ell activated carbon flue gas s._x NO_x

Anticlas.ogenic Effect of Redis.illed Cow's.Urine Dis.illate in Human Peripheral Lymphocytes.Challenged With Manganes. Dioxide and Hexavalent Chromium

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Biomedical and Environmental s.iences 2006年第6期19卷 487-494页

作者： DIPANWItA DUttA s. s.RAVANA DEVI K. KRIs.NAMURtHI t. CHAKRABARtI Environmental Biotechnology Divis.on National Environmental Engineering Research Institute (NEERI)Nehru MargNagpur-440020INDIA

Objective to s.udy the anticlas.ogenic effect of redis.illed cow＇s.urine dis.illate （RCUD） in human peripheral lymphocytes.（HLC） challenged with manganes. dioxide and hexavalent chromium. Methods.the anticlas.ogenic activity of redis.illed cow＇s.urine dis.illate was.s.udied in human polymorphonuclear leukocytes.（HPNLs. and human peripheral lymphocytes.in vitro challenged with manganes. dioxide and hexavalent chromium as.es.ablis.ed genotoxicants.and clas.ogens.which could caus. induction of DNA s.rand break, chromos.mal aberration and micronucleus. three different levels.of RCUD： 1 μL/mL, 50 μL/mL and 100 μL/mL, were us.d in the s.udy. Res.lts.Manganes. dioxide and hexavalent chromium caus.d s.atis.ically s.gnificant DNA s.rand break, chromos.mal aberration and micronucleus.formation, which could be protected by redis.illed cow＇s.urine dis.illate. Conclus.on the redis.illed cow＇s.urine dis.illate pos.es.s.s.rong anfigenotoxic and antielas.ogenic properties.agains. HPNLs.and HLC treated with Cr^＋6 and MnO2. this.property is.mainly due to the antioxidants.pres.nt in RCUD.

关键词： Redis.illed cow's.urine dis.illate (RCUD) DNA s.rand break Clas.ogenicity Chromos.mal aberration Micronuclei Hexavalent chromium and manganes. dioxide