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Techniques for overcoming atretic changes of the portal vein in living donor liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2020年第4期19卷 311-317页

作者： jeong-Moo lee Kwang-Woong lee Department of Surgery Seoul National University College of Medicine101 Daehak-roJongno-guSeoul 03080Korea

Background:Spontaneous diversion of the portal flow through collateral vessels into the systemic circulation is frequently observed in liver transplant recipients with severe portal *** induces main portal vein atretic change and modifies flow into the collateral even after donor graft *** atretic changes make liver transplantation *** this article we described several methods for overcoming this challenge by appropriate surgical ***:Three anastomotic techniques for living donor liver transplantation were performed in patients with atretic changes in the portal ***:The three techniques were(1)venoplasty to widen the diameter by using the recipient’s portal vein,and the diameter of the recipient’s portal vein was enlarged using their own portal vein stump patch;(2)conduit with cryopreserved vessels,and we dissected around the superior mesenteric vein and splenic vein junction and a conduit was built using the cryopreserved vessels;and(3)left gastric varix to portal vein anastomosis,if the recipients had large gastric varix and variceal wall was sufficiently thick for ***:Selection of optimal methods for portal vein anastomosis is essential in patients with atrophic change on the portal *** these methods are used aptly,they can be considered as favorable methods for overcoming each situation.

关键词： Atretic portal vein Liver transplantation Anastomosis

A case with acute-on-chronic liver failure receiving liver transplantation during daclatasvir and asunaprevir therapy in chronic hepatitis C patient

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Gastroenterology Report 2019年第5期7卷 371-373,I0003页

作者： Wonhyeong Park Jihwan Jung Soo hyun Yang Danbi lee Hyo jeong Kang Department of Internal Medicine Veterans Health Service Medical CenterSeoulKorea Department of Internal Medicine Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea Department of Pathology Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea

We report a case with hepatitis C virus genotype 1 b liver cirrhosis who received liver transplantation because of acute-onchronic liver failure during daclatasvir(DSV)and asunaprevir(ASV)combination *** our knowledge,this is the first case received liver transplantation during DSVtASV ***,clinicians should pay particular attention to the possibility of acute liver failure during DSV and ASV combination therapy.

关键词： Chronic hepatitis C liver failure:daclatasvir asunaprevir

Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael J.lee Ryota L.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

Association between Occupational Change Trajectories and Mental Health: Results from the Korean Longitudinal Study of Aging

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International Journal of Mental Health Promotion 2023年第4期25卷 579-594页

作者： jeong Min Yang Hyeon Ji lee Jae hyun Kim Institute for Digital Life Convergence Dankook UniversityCheonan31116South Korea Department of Public Health General Graduate School of Dankook UniversityCheonan31116South Korea Department of Health Administration College of Health ScienceDankook UniversityCheonan31116South Korea

Objectives:This study was to longitudinally investigate the association between occupational change trajectories and mental health in the Korean population aged 45 years and older from the Korean Longitudinal Study of Aging(KLo-SA).Methods:After excluding missing values,the data of 6,224 participants from thefirst to eighth waves of the KLo-SA were analyzed using t-test,Analysis of variance(ANOVA),Group-based Trajectory Model(GBTM)from 1–5th KLoSA and Time-Lagged Generalized estimating equation(GEE)model from 5–8th KLoSA to analyze the association between occupational change trajectories and mental health in the Korean population aged 45 years and ***:An analysis of the association between occupational change trajectories and mental health demonstrated that,among all age group,the“sustained in unemployment”group had a worse MMSE and CESD score compared to“sustained WC”*** the under-54 age group,those aged≥55 years demonstrated reductions in the MMSE and CESD scores in the sustained unemployment and the changed working condition from Standard BC to Unemployment groups,whereas those who underwent a change from the Standard WC to unemployment group only demonstrated a reduction in MMSE ***:There was a close relationship between occupational change trajectories and mental ***,this study can serve as the foundation for policies and institutional measures to manage the deteriorate mental health in the late middle-aged and older population.

关键词： CESD change in job employment status mental health MMSE trajectory

SMINER:Detecting Unrestricted and Misimplemented Behaviors of Software Systems Based on Unit Test Cases

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Computers, Materials & Continua 2023年第5期75卷 3257-3274页

作者： Kyungmin Sim jeong hyun Yi Haehyun Cho School of Software Soongsil UniversitySeoul06978Korea

Despite the advances in automated vulnerability detection approaches,security vulnerabilities caused by design flaws in software systems are continuously appearing in real-world *** security design flaws can bring unrestricted and misimplemented behaviors of a system and can lead to fatal vulnerabilities such as remote code execution or sensitive data ***,it is an essential task to discover unrestricted and misimplemented behaviors of a ***,it is a daunting task for security experts to discover such vulnerabilities in advance because it is timeconsuming and error-prone to analyze the whole code in ***,most of the existing vulnerability detection approaches still focus on detecting memory corruption bugs because these bugs are the dominant root cause of software *** paper proposes SMINER,a novel approach that discovers vulnerabilities caused by unrestricted and misimplemented *** first collects unit test cases for the target system from the official ***,preprocess the collected code *** uses pre-processed data to show the security policies that can occur on the target system and creates a test case for security policy *** demonstrate the effectiveness of SMINER,this paper evaluates SMINER against Robot Operating System(ROS),a real-world system used for intelligent robots in Amazon and controlling satellites in National Aeronautics and Space Administration(NASA).From the evaluation,we discovered two real-world vulnerabilities in ROS.

关键词： Security vulnerability test case generation security policy test robot operating system vulnerability assessment

Crystal plasticity finite element simulations on extruded Mg-10Gd rod with texture gradient

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Journal of Magnesium and Alloys 2024年第8期12卷 3409-3430页

作者： Jaeseong lee Dirk Steglich Youngung jeong Department of Materials Convergence and System Engineering Changwon National University25 Changwondaehak-roChangwonRepublic of Korea Helmholtz-Zentrum Hereon Institute of Material Systems ModelingD-21502 GeesthachtGermany School of Materials Science and Engineering Changwon National University25 Changwondaehak-roChangwonRepublic of Korea

The mechanical properties of an extruded Mg-10Gd sample, specifically designed for vascular stents, are crucial for predicting its behavior under service conditions. Achieving homogeneous stresses in the hoop direction, essential for characterizing vascular stents, poses challenges in experimental testing based on standard specimens featuring a reduced cross section. This study utilizes an elasto-visco-plastic self-consistent polycrystal model(ΔEVPSC) with the predominant twinning reorientation(PTR) scheme as a numerical tool, offering an alternative to mechanical testing. For verification, various mechanical experiments, such as uniaxial tension, compression, notched-bar tension, three-point bending, and C-ring compression tests, were conducted. The resulting force vs. displacement curves and textures were then compared with those based on the ΔEVPSC model. The computational model's significance is highlighted by simulation results demonstrating that the differential hardening along with a weak strength differential effect observed in the Mg-10Gd sample is a result of the interplay between micromechanical deformation mechanisms and deformation-induced texture evolution. Furthermore, the study highlights that incorporating the axisymmetric texture from the as-received material incorporating the measured texture gradient significantly improves predictive accuracy on the strength in the hoop direction. Ultimately, the findings suggest that the ΔEVPSC model can effectively predict the mechanical behavior resulting from loading scenarios that are impossible to realize experimentally, emphasizing its valuable contribution as a digital twin.

关键词： Crystal plasticity Texture Finite element C-ring Three-point bending

A preliminary study of dietary protein requirement of juvenile marbled flounder (Pseudopleuronectes yokohamae)

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Animal Nutrition 2021年第2期7卷 548-555页

作者： jeong-Hyeon Cho Seunghyung lee Bong-Joo lee Sang-Woo Hur Kang-Woong Kim Maeng-hyun Son Dong-Jae Yoo Inland Fisheries Research Institute National Institute of Fisheries ScienceGapyeong12453South Korea Department of Marine Bio-materials and Aquaculture Pukyong National UniversityBusan48513South Korea Aquafeed Research Center National Institute of Fisheries SciencePohang37517South Korea Gyeongsangbuk-do Fisheries Resources Institute Yeongdeok36405South Korea Gyeongsangbuk-do Native Fish Business Center Uiseong37366South Korea

An 8-week feeding trial was conducted to determine the optimal dietary protein level for juvenile marbled *** semi-purified test diets were formulated to contain different protein levels(CP)including 42.7%,47.4%,53.3%,58.8%,and 64.5%(dry matter),named as CP42.7,CP47.4,CP53.3,CP58.8,and CP64.5,*** hundred and twenty-five juveniles(6.0±0.1 g)were randomly distributed into 15 tanks(300 L tanks),resulting in 35 fish per tank(n-3 tanks).Fish were fed the test diets 5 times per day until *** CP58.8 resulted in the highest gain in weight and the best efficiency in feed utilization among the tested protein levels(P<0.05).Fish fed the CP58.8 diet showed significantly higher whole-body protein and lipid contents than the fish that were fed the other diets(P<0.05).Fish fed the CP53.3,CP58.8,and CP64.5 diets showed a significantly higher dorsal-muscle lipid content than the fish that were fed the CP42.7 and CP47.4 diets(P<0.05).The one-slope straight broken-line regression analysis on the results of the thermal growth coefficient and feed conversion ratio indicated that the estimated optimum dietary protein level was 58.8%.Taken together,it is suggested that the dietary protein level of 58.8%is optimal for better growth and high efficiency in feed utilization for the juvenile marbled flounder.

关键词： Marbled flounder Pseudopleuronectes yokohamae Protein requirement Growth performance Proximate composition

Stud welding for fixation of cryogenic insulation of membrane tanks in LNG ship building

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中国有色金属学会会刊：英文版 2009年第B9期19卷 271-275页

作者： jeong-Soo lee Young-Soo RYU Nam-In KIM Bong-Joon KIM Yoo-Kyung KIM Myung-hyun KIM Hanjin Heavy Industries & Construction Co. Ltd Department of Naval Architecture and Ocean Engineering Pusan National University

The support plates including all of the inner hulls such as E grade steel, weld seams and SUS304L were considered to establish the optimal stud welding condition in LNG ship building. The stainless steel plate was especially applied to the bracket on the liquid dome. The polished and etched surfaces of the welded stud and support plate were examined if the bead was properly formed. With the micrographic examination, the fusion boundary of metal weld zone formed by stud welding was analyzed to optimize the welding parameters. And also the analysis of the unacceptable welding faults such as cold and hot weld were performed. The mechanical tests such as tensile tests and bending tests were carried out to reveal any abnormal variation in the relationship of process parameters and the strength.

关键词：螺柱焊接 LNG船绝缘膜优化工艺参数低温坦克不锈钢板最佳条件

Metal stents placement for refractory pancreatic duct stricture in children

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World Journal of Gastroenterology 2018年第3期24卷 408-414页

作者： In Sook jeong Sung Hee lee Seak Hee Oh Do hyun Park Kyung Mo Kim Department of Pediatrics University of Ulsan College of MedicineAsan Medical Center Children’s Hospital Department of Internal Medicine University of Ulsan College of MedicineAsan Medical Center

AIM To evaluate the use of fully covered self-expandable metal stents(FCSEMSs) for pancreatic duct strictures in children with chronic *** Eight patients with refractory benign dominant stricture of the main pancreatic duct(MPD) were enrolled through chart reviews between December 2014 and June 2017 in a single center. Endoscopic retrograde cholangiopancreatography(ERCP) with placement of a 6-mm FCSEMS with dual flaps was performed. Endoscopic removal of FCSEMSs was performed with a snare or rat-tooth forceps. All procedures were performed by a pediatric gastroenterologist. For the assessment of outcomes, technical and clinical success, adverse events, and stent patency were evaluated *** The placement and removal of the FCSEMSs were successful in all 8 patients. Five patients were boys and 3 were girls. The median age at initial FCSEMS placement was 12 years(range, 5-18 years). The diameters of all the inserted stents were 6 mm, and the lengths were 4-7 cm. The median indwelling time was 6 mo(range, 3-10 mo). No pancreatic sepsis, pancreatitis, cholestasis, or mortality occurred. There was no proximal and distal migration. All subjects showed a patent stent. On follow-up ERCP, the mean diameter of the stricture improved from 1.1 mm to 2.8 mm(P < 0.05), whereas that of upstream dilation improved from 8.4 mm to 6.3 mm(P < 0.05).CONCLUSION This initial experience showed that temporary FCSEMS placement is feasible and safe for the management of refractory benign MPD stricture in children.

关键词： Chronic pancreatitis Pancreatic duct Selfexpandable metal stent Child Endoscopic retrograde cholangiopancreatography