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N-terminal pro-B-type natriuretic peptide as prognostic marker for patients of non ST-segment elevation myocardial infarction

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Journal of Central South University 2013年第8期20卷 2226-2232页

作者： SHON Ho Sun HWANG Kyung Kuk BAE Jang Whan KIM Kyung Ah lee jong yun RYU Keun Ho Database and Bioinformatics Laboratory School of Electrical & Computer Engineering also PSM of School of Medicine Chungbuk National University Department of Medicine School of Medicine Chungbuk National University Department of Biomedical Engineering School of Medicine Chungbuk National University Department of Informatics and Convergence Chungbuk National University Cheongju

In this work, we analyzed only the patients of the NSTEMI (non ST-segment elevation myocardial infarction) who arrived at the hospital within 12 h after symptoms started. Using NSTEMI follow-up data within, the characteristics of the clinical data, the risk factor, and the blood tested in the hospital visit were analyzed for MACE (major adverse cardiac events) patients. MACE includes cardiac death, MI (myocardial infarction), Re-PCI, and CABG (coronary artery bypass graft). As a result, from the NSTEMI patients which can be followed up for over 12 m, NT-ProBNP (p=0.014) and age (p=0.045) are found to be the independent risk factors related to MACE. Accordingly, they can be useful for the diagnosis and prognosis for NSTEMI patients as a biomarker.

关键词： non ST-segment elevation myocardial infarction NT-ProBNP cardiovascular disease

Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第2期20卷 483-484页

作者： yun Li Junfang Wu Department of Anesthesiology&Shock Trauma and Anesthesiology Research(STAR)CenterUniversity of Maryland School of MedicineBaltimoreMDUSA

Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability *** in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth *** survival changes have led neurotrauma researchers to examine how SCI interacts with brain *** health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关键词： alterations inflammation injury

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： Jin-Peng Wang Guo-Cui Mao Hui-Lin Jiang Bao-Xia Dong yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials

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Neural Regeneration Research 2025年第9期20卷 2437-2453页

作者： Siyi Xu Junqiu Jia Rui Mao Xiang Cao yun Xu Department of Neurology Nanjing Drum Tower HospitalClinical College of Jiangsu UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalChinese Academy of Medical Science&Peking Union Medical CollegeNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjingJiangsu ProvinceChina Nanjing Neurology Medical Center NanjingJiangsu ProvinceChina

Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health *** optimal therapies and improving the long-term neurological functions of patients with acute central nervous system injuries are urgent *** are susceptible to damage after acute central nervous system injury,and this leads to the release of toxic levels of reactive oxygen species,which induce cell ***,a selective form of autophagy,is crucial in eliminating redundant or damaged mitochondria during these *** evidence has highlighted the significant role of mitophagy in acute central nervous system *** this review,we provide a comprehensive overview of the process,classification,and related mechanisms of *** also highlight the recent developments in research into the role of mitophagy in various acute central nervous system injuries and drug therapies that regulate *** the final section of this review,we emphasize the potential for treating these disorders by focusing on mitophagy and suggest future research paths in this area.

关键词： autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control mitophagy spinal cord injury subarachnoid hemorrhage traumatic brain injury

Effect of esterification reaction of citric acid and ethylene glycol on the formation of multi-shelled cobalt oxide powders with superior electrochemical properties

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Nano Research 2014年第12期7卷 1738-1748页

作者： Gi Dae Park jong-Heun lee Jung-Kul lee yun Chan Kang Department of Materials Science and Engineering Korea University Anam-Dong Seongbuk-Gu Seou1136-713 Republic of Korea Department of Chemical Engineering Konkuk University 1 Hwayang-dong Gwangjin-gu Seou1143-701 Republic of Korea

In this study, for the first time, polymeric precursors have been used in the preparation of yolk-shell powders using a large-scale spray drying process. An esterification reaction between the carboxyl group of citric acid and the hydroxyl group of ethylene glycol inside the droplet produced organic polymers during the drying process of the droplet. During the spray drying process, the polymeric precursors enabled the formation of multi-shell cobalt oxide yolk- shell powders with superior electrochemical properties. The maximum number of shells of the particles in the yolk-shell powders post-treated at 300, 400, and 500 ℃ were six, five, and four, respectively. The initial discharge capacities of the cobalt oxide yolk-shell powders post-treated at 300, 400, and 500 ℃ were 1,188, 1,331, and 1,110 mAh·g^-1, and their initial charge capacities were 868, 1,005, and 798 mAh·g^-1, respectively. The discharge capacities of the powders post- treated at 300, 400, and 500 ℃ after 100 cycles were 815, 958, and 670 mAh·g^-1, respectively and their corresponding capacity retentions measured after the first cycles were 92%, 93%, and 82%, respectively. The pure phase Co3O4 yolk-shell powders post-treated at 400 ℃ had low charge transfer resistance and high lithium-ion diffusion rate.

关键词： yolk-shell energy storage synthesis design lithium battery spray drying

An in-situ Raman spectroscopic study on potential-pO^(2-) phase diagram of lanthanum in LiCl-KCl eutectic melt

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Journal of Rare Earths 2020年第7期38卷 793-800,I0004页

作者： Seung Park jong-IL yun Department of Nuclear and Quantum Engineering.KAIST Yuseong-guDaejeon 34141Republic of Korea

The oxidative reaction between lanthanum trichloride and oxide ion was studied in the molten LiCl-KCl eutectic at 773 K by in-situ Raman spectroscopy using an yttria-stabilized zirconia electrode in conjunction with electrochemical *** formation of lanthanum oxychloride,LaOCl(s),was confirmed by studying the vibrational properties of crystalline LaOCl and X-ray diffraction *** solubility product of LaOCl in the LiCl-KCl molten eutectic at 773 K is found to be pKsp(LaOCl)=7.569±0.100,by combining the results of Raman spectroscopy and potentiometric titration with the addition of barium *** use of Raman spectroscopic quantitation of dissolved lanthanum ions in the system allows faster and more accurate determination of the stable phase of lanthanum as well as the solubility product of LaOCl compared with that measured by potentiometric titration *** on experimentally obtained pKsp and standard equilibrium potentials,the potentialpO2- phase diagram of lanthanum in the molten LiCl-KCl eutectic was reported.

关键词： Lanthanum Solubility product E-pO2-diagram Raman spectroscopy Chloride molten salt Rare earths

Radiolarians from the Pohang Basin,Southeast Korea and Paleoceanographic Implications

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Acta Geologica Sinica(English Edition) 2012年第6期86卷 1426-1433页

作者： Young-Suk BAK jong-Deock lee Hyesu yun Jinyong OH Seong-Joo lee Kyungpook National University Chonbuk National University Chungnam National University

We identified a total of 101 species and two subspecies of radiolarians belonging to 56 genera from 95 samples collected from the Hagjeon and Duho Formations in the Pohang Basin of the southeastern Korean Peninsula. On the basis of the biostratigraphic range of Cyrtocapsella cornuta and Theocorys redondoensis, the depositional period of the upper Hagjeon and lowest Duho Formations was determined to be early to late Middle Miocene. The occurrence of deep-dwelling radiolarians indicates that the paleobathymetry seems to become gradually progressing toward an upper bathyal environment in the middle part of the Hagjeon Formation. However, we prefer to accept another interpretation for the occurrence of deep-sea indicators in the Hagjeon and the lowest part of the Duho Formations, and consider the presence of a region of upwelling cold water that might have simulated a deep-water environment in relatively shallow water. This interpretation is based on the present upwelling of a cold-water mass off the southeast coast of Korea, the occurrence of upwelling microfossils from the Pohang Basin, and the effect of the closing of the Korea Strait approximately 15 Ma. We also considered that the uppermost part of the studied section represents a shallow-water environment.

关键词： radiolarian depositional environment upweHing Pohang Basin

The detection, extraction and parameter estimation of extreme-mass-ratio inspirals with deep learning

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 86-96页

作者： Qianyun yun Wen-Biao Han Yi-Yang Guo He Wang Minghui Du Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences Shanghai Astronomical Observatory Chinese Academy of Sciences School of Physics and Astronomy Shanghai Jiao Tong University School of Astronomy and Space Science University of Chinese Academy of Sciences Taiji Laboratory for Gravitational Wave Universe (Beijing/Hangzhou) University of Chinese Academy of Sciences Lanzhou Center for Theoretical Physics Key Laboratory of Theoretical Physics of Gansu Province Key Laboratory of Quantum Theory and Applications of MoE Lanzhou University Institute of Theoretical Physics & Research Center of Gravitation Lanzhou University International Centre for Theoretical Physics Asia-Pacific (ICTP-AP) University of Chinese Academy of Sciences (UCAS) Center for Gravitational Wave Experiment National Microgravity Laboratory Institute of Mechanics Chinese Academy of Sciences

One of the primary goals of space-borne gravitational wave detectors is to detect and analyze extreme-mass-ratio inspirals(EMRIs). This task is particularly challenging because EMRI signals are complex, lengthy, and faint. In this work, we introduce a2-layer convolutional neural network(CNN) approach to detect EMRI signals for space-borne detectors, achieving a true positive rate(TPR) of 96.9% at a 1% false positive rate(FPR) for signal-to-noise ratio(SNR) from 50 to 100. Especially, the key intrinsic parameters of EMRIs such as the mass, spin of the supermassive black hole(SMBH) and the initial eccentricity of the orbit can also be inferred directly by employing a neural network. The mass and spin of the SMBH can be determined at 99% and 92% respectively. This will greatly reduce the parameter spaces and computing cost for the following Bayesian parameter *** model also has a low dependency on the accuracy of the waveform model. This study underscores the potential of deep learning methods in EMRI data analysis, enabling the rapid detection of EMRI signals and efficient parameter estimation.

关键词： gravitational wave EMRIs deep-learing

Characterization of Wollastonite Glass-ceramics Made from Waste Glass and Coal Fly Ash

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Journal of Materials Science & Technology 2013年第2期29卷 149-153页

作者： Soon-Do Yoon jong-Un lee Jeong-Hwan lee Yeon-Hum yun Wang-Jung Yoon School of Biotechnology and Chemical Engineering Chonnam National University Department of Energy & Resources Engineering Chonnam National University

The crystallization behavior of wollastonite glass-ceramics was investigated by means of X-ray diffraction （XRD） analysis and surface morphological observations, and the chemical compositions were evaluated by field emission-scanning electron microscopy （FE-SEM） and energy dispersive X-ray spectroscopy （EDS）. Various heat treatment temperatures （850, 900, 950, 1000 and 1050 ℃） were used to obtain glass-ceramics of the ideal wollastonite crystal phase as well as optimum mechanical properties and chemical durability. From XRD, FE-SEM and EDS, the crystallization of acicular crystal phase in the matrix was achieved at heat treatment temperature of 1000 and 1050 ℃, and wollastonite （CaSiO3） was found in the acicular type main crystal phase in the glass-ceramics. Various properties, such as density, compressive strength, bending strength and chemical durability were also examined. The mechanical properties of glass-ceramics obtained at the heat treatment temperature of 1000 and 1050 ℃ were superior to those obtained at the heat treatment temperature of 850 ℃.

关键词： Coal fly ash Waste glass Mechanical properties Glass-ceramics