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Journal of Literature and Art Studies 2016年第7期6卷 769-774页

作者： lai Peng Sun Yat-sen University Guangzhou China

This is a poem review which analyzes The Mill that was written by a new poet in China, looking at it from the conceptual perspective. The conceptual shift and collocation between concreteness and abstractness enable her poems to carry both linguistic power and emotional strength; the conceptual images created by her abstract thinking and unique perception make her poems achieve originality and readability; her conceptual self built by the use of first person pronouns is actually not that of a person but that of a personified mule who was indignant about its heavy workload yet unable to speak against its predestined destiny. Although suffering from brain paralysis, the poet is shown by this review to be a sensible manipulator of words, which reveal the unique beauty in her language and show the suppressed sadness in her heart.

关键词： poem review conceptual shift conceptual collocation concreteness abstractness

POLYMERIZATION OF ACRYLONITRILE WITH ORGANOLANTHANIDES AS SINGLE-COMPONENT CATALYSTS

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Chinese Journal of Polymer Science 2001年第1期19卷 89-91页

作者： lai-qiang Ying Xiao-wei Ba Yu-ying Zhao Gang Li Tao Tang Ying-tai Jin Changchun Institute of Applied Chemistry Chinese Academy of SciencesChangchun 130022Chin

Ind_(2)Y(μ-Et)_(2)AlEt_(2) and Ind_(2)LnN(i-Pr)_(2)(Ln=Y,Yb)were used as a single-component catalyst for the polymerization of acrylonitrile(AN)*** regularity of polymerization of AN and stereoregularity of polyacrylonitrile(PAN)were also studied in both *** catalysts can produce PAN with molecular weight from 10,000 to 30,*** addition,the catalytic activity and molecular weights were increased by the addition of PhONa.

关键词： acrylonitrile organolanthanide polymerization

Strategies of Removing Residual Lithium Compounds on the Surface of Ni-Rich Cathode Materials

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Chinese Journal of Chemistry 2021年第1期39卷 189-198页

作者： Yuefeng Su Linwei Li Gang Chen lai Chen Ning Li Yun Lu Liying Bao Shi Chen Feng Wu Beijing Key Laboratory of Environmental Science and Engineering Schoo of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China

Ni-rich cathode materials have become one of the most promising cathode materials for advanced high-energy Li-ion batteries(LIBs)owing to their high specific ***,Ni-rich cathode materials are sensitive to the trace H2O and CO2 in the air,and tend to react with them to generate LiOH and Li2COg at the particle surface region(named residual lithium compounds,labeled as RLCs).The RLCs will deteriorate the comprehensive performances of Ni-rich cathode materials and make trouble in the subsequent manufacturing process of electrode,including causing low initial coulombic efficiency and poor storage property,bringing about potential safety hazards,and gelatinizing the electrode ***,it is of considerable significance to remove the *** have done a lot of work on the corresponding field,such as exploring the formation mechanism and elimination *** paper investigates the origin of the surface residual lithium compounds on Ni-rich cathode materials,analyzes their adverse effects on the per-formance and the subsequent electrode production process,and summarizes various kinds of feasible methods for removing the ***,we propose a new research direction of eliminating the lithium residuals after comparing and summing up the *** hope this work can provide a reference for alleviating the adverse effects of residual lithium compounds for Ni-rich cathode materials'industrial production.

关键词： Materials science Rechargeable battery Lithium Ni-rich cathode material Residual lithium compounds

Compound C620-0696,a new potent inhibitor targeting BPTF,the chromatin-remodeling factor in non-small-cell lung cancer

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Frontiers of Medicine 2020年第1期14卷 60-67,F0004页

作者： Jiahui Xu Qianqian Wang Elaine lai Han Leung Ying Li Xingxing Fan Qibiao Wu Xiaojun Yao Liang Liu State Key Laboratory of Quality Research in Chinese Medicine Macao Institute for Applied Research in Medicine and HealthMacao University of Science and TechnologyMacao(SAR)519020China Respiratory Medicine Department Taihe HospitalHubei University of MedicineShiyan 236600China Department of Thoracic Surgery Guangzhou Institute of Respiratory Health and State Key Laboratory of Respiratory DiseaseThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510182China

Bromodomain PHD-finger transcription factor(BPTF)is the largest subunit of the nucleosome remodeling factor and plays an important role in chromatin remodeling for gene activation through its association with histone acetylation or *** is also involved in oncogene transcription in diverse progressions of *** clinical trials for inhibitors of bromodomain and extra-terminal family proteins in human cancers,no potent and selective inhibitor targeting the BPTF bromodomain has been *** this study,we identified a potential inhibitor,namely,C620-0696,by computational docking modeling to target *** of biolayer interferometry revealed that compound C620-0696 exhibited high binding affinity to the BPTF ***,C620-0696 was cytotoxic in BPTF with a high expression of non-small-cell lung cancer(NSCLC)*** suppressed the expression of the BPTF target gene c-MYC,which is known as an oncogenic transcriptional regulator in various cancers.C620-0696 also partially inhibited the migration and colony formation of NSCLC cells owing to apoptosis induction and cell cycle ***,our study presents an effective strategy to target a bromodomain factor-mediated tumorigenesis in cancers with small molecules,supporting further exploration of the use of these inhibitors in oncology.

关键词： BPTF small molecule epigenetics non-small-cell lung cancer

Differentiation of rat bone marrow stem cells in liver after partial hepatectomy

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World Journal of Gastroenterology 2006年第31期12卷 5051-5054页

作者： Yu-Tao Zhan Yu Wang lai Wei Bin Liu Hong-Song Chen Xu Cong Ran Fei Department of Gastroenterology Beijing Tongren Hospital Capital Medical University Beijing 100730 China Hepatology Institute Beijing University People's Hospital Beijing 100044 China

AIM： To investigate the differentiation of rat bone marrow stem cells in liver after partial hepatectomy. METHODS： Bone marrow cells were collected from the tibia of rat with partial hepatectomy, the medial and left hepatic lobes were excised. The bone marrow stem cells （Thy^＋CD3^-CD45RA^- cells） were enriched from the bone marrow cells by depleting red cells and fluorescence-activated cell sorting. The sorted bone marrow stem cells were labeled by PKH26-GL in vitro and autotransplanted by portal vein injection. After 2 wk, the transplanted bone marrow stem cells in liver were examined by the immunohistochemistry of albumin （hepatocyte-specific marker）. RESULTS： The bone marrow stem cells （Thy^＋CD3^-CD45RA^- cells） accounted for 2.8% of bone marrow cells without red cells. The labeling rate of 10 μM PKH26- GL on sorted bone marrow stem cells was about 95%. There were sporadic PKH26-GL-labeled cells among hepatocytes in liver tissue section, and some of the cells expressed albumin. CONCLUSION： Rat bone marrow stem cells can differentiate into hepatocytes in regenerative environment and may participate in liver regeneration after partial hepatectomy.

关键词： Bone marrow stem cells Liver regeneration Differentiation

Spatial Interpolation of Soil Texture Using Compositional Kriging and Regression Kriging with Consideration of the Characteristics of Compositional Data and Environment Variables

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Journal of Integrative Agriculture 2013年第9期12卷 1673-1683页

作者： ZHANG Shi-wen SHEN Chong-yang CHEN Xiao-yang YE Hui-chun HUANG Yuan-fang lai Shuang China Agricultural University/Key Laboratory of Arable Land Conservation (North China) Minstry of Agriculture/Key Laboratory of Agricultural Land Quality MonitoringMinistry of Land and Resources School of Earth and Environment Anhui University of Science and Technology Afforestation Management Office Sichuan Forestry Department

The spatial interpolation for soil texture does not necessarily satisfy the constant sum and nonnegativity constraints. Meanwhile, although numeric and categorical variables have been used as auxiliary variables to improve prediction accuracy of soil attributes such as soil organic matter, they （especially the categorical variables） are rarely used in spatial prediction of soil texture. The objective of our study was to comparing the performance of the methods for spatial prediction of soil texture with consideration of the characteristics of compositional data and auxiliary variables. These methods include the ordinary kriging with the symmetry logratio transform, regression kriging with the symmetry logratio transform, and compositional kriging （CK） approaches. The root mean squared error （RMSE）, the relative improvement value of RMSE and Aitchison＇s distance （DA） were all utilized to assess the accuracy of prediction and the mean squared deviation ratio was used to evaluate the goodness of fit of the theoretical estimate of error. The results showed that the prediction methods utilized in this paper could enable interpolation results of soil texture to satisfy the constant sum and nonnegativity constraints. Prediction accuracy and model fitting effect of the CK approach were better, suggesting that the CK method was more appropriate for predicting soil texture. The CK method is directly interpolated on soil texture, which ensures that it is optimal unbiased estimator. If the environment variables are appropriately selected as auxiliary variables, spatial variability of soil texture can be predicted reasonably and accordingly the predicted results will be satisfied.

关键词： compositional kriging auxiliary variables regression kriging symmetry logratio transform

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免疫细胞在肾脏缺血再灌注损伤修复中的作用研究进展

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中华细胞与干细胞杂志（电子版） 2024年第1期14卷 45-50页

作者：曹守青来东焦启龙安哲昆李修彬河北北方学院研究生院张家口075000 解放军总医院第三医学中心泌尿外科医学部北京100039 南开大学医学院天津300071 山西医科大学基础医学院太原030001

急性肾损伤(AKI)是一种常见的临床综合征,我国住院人群AKI的发病率高达11.6%,AKI发生后容易进展为慢性肾病(CKD)甚至终末期肾病(ESRD)。缺血再灌注损伤(IRI)是AKI的主要病因之一。肾小管上皮细胞是IRI致AKI发生过程中受损的主要细胞类型... 详细信息

急性肾损伤(AKI)是一种常见的临床综合征,我国住院人群AKI的发病率高达11.6%,AKI发生后容易进展为慢性肾病(CKD)甚至终末期肾病(ESRD)。缺血再灌注损伤(IRI)是AKI的主要病因之一。肾小管上皮细胞是IRI致AKI发生过程中受损的主要细胞类型,也是肾脏修复过程中细胞再生的主要细胞来源。在AKI发生发展以及损伤修复的过程中,免疫细胞能够调节肾小管上皮细胞的损伤、增殖以及再上皮化等多种生物过程,最终导致AKI的不同结局。本文就IRI导致的AKI发生过程中免疫细胞发挥的作用以及领域内的挑战和发展作一综述。

关键词：肾小管上皮细胞免疫细胞肾脏缺血再灌注肾脏损伤修复

水动力学模型与集合卡尔曼滤波耦合的实时校正多变量分析方法

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水科学进展 2009年第2期20卷 241-248页

作者：赖锡军中国科学院南京地理与湖泊研究所湖泊与环境国家重点实验室江苏南京210008

为减少非恒定水流计算中的不确定性,在水流随机运动系统状态空间模型基础上,应用集合卡尔曼滤波(EnKF)技术建立了非恒定水流分析的实时更新(校正)方法。该方法适用于非线性的随机微分方程,过程和观测噪声可以是非正态分布。同时,为充分... 详细信息

为减少非恒定水流计算中的不确定性,在水流随机运动系统状态空间模型基础上,应用集合卡尔曼滤波(EnKF)技术建立了非恒定水流分析的实时更新(校正)方法。该方法适用于非线性的随机微分方程,过程和观测噪声可以是非正态分布。同时,为充分利用水位、流量等误差量级相差巨大的观测中所蕴含的有效信息,导出了EnKF多变量分析格式。以明渠单峰洪水过程的合成数据为例,考察了运用建立的实时更新方法分析预报一维洪水演进的性能。重点对比了采用不同精度等级下的水位和流量观测资料进行滤波的效果。在中国现行标准规定的允许观测误差范围内,以水位观测进行一维洪水动力学模型的滤波分析可有效地控制误差、估计流量、识别水流运动系统状态。长江干流清溪场至万县江段实际洪水计算还证实:该方法通过插入即时观测,可实时更新模型状态,给出与实际更为接近的计算。

关键词：水动力学模型集合卡尔曼滤波非恒定流实时校正

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车载直流电源的故障预测与健康评估系统开发

汽车科技 2024年第5期 13-23,46页

作者：余云加彭子健吴来杰文国军余叶威广电计量检测集团股份有限公司武汉430074 中国地质大学(武汉) 武汉430074

车载电源作为一种移动电站,是野外作业的主要电能来源。其工作环境恶劣且情况复杂,因此各类元器件可能会出现不同程度的故障,若在故障出现早期能及时予以准确预测并诊断,会极大提高车载电源的安全性和可靠性。由于车载电源系统复杂度高... 详细信息

车载电源作为一种移动电站,是野外作业的主要电能来源。其工作环境恶劣且情况复杂,因此各类元器件可能会出现不同程度的故障,若在故障出现早期能及时予以准确预测并诊断,会极大提高车载电源的安全性和可靠性。由于车载电源系统复杂度高难以准确建模,且实际监测数据存在冗余、含有噪声且样本不平衡,传统的故障诊断方法难以对系统进行准确预测与健康评估。鉴于此本文采用数据驱动预测法,通过将机器学习算法与健康评估算法相结合,开展车载直流电源的故障预测与健康评估方法研究。主要内容包括:首先,基于直流电源的组成结构和工作原理,构建健康状态评估体系。针对目前设备健康状态估计的研究中,通常只将采集到的直流电源的电压或电流作为单一故障特征参数,容易导致估计结果不准确。此外,目前的评价方法很少考虑数据噪声对评价结果的影响,容易导致评价结果异常。为了解决以上两个问题,本文首先将输出电压、纹波电压、输出电流、外壳温度等状态指标引入到评价指标中。在此基础上,采用层次分析结合熵权法的组合赋权法确定各评价指标权重。最后采用基于加权马氏距离的多参数健康评估方法对电源进行健康状态评估。其次,研究基于Bi-LSTM模型的直流电源故障预测,将历史输出电压、纹波电压、输出电流、外壳温度等状态指标进行Min-MaxScaler归一化,将处理后的数据作为网络输入,利用Bi-LSTM加LSTM网络模型进行故障预测,并通过对预测曲线和实验数据的对比分析,证实此预测方法的有效性。

关键词：直流电源健康状态评估故障预测

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Laboratory investigation on the mechanical behavior of ice-saturated frozen loess

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Research in Cold and Arid Regions 2014年第4期6卷 314-321页

作者： XiangTian Xu YuanMing lai JinYi Chai CaiXia Fan Institute of Transportation Inner Mongolia University State Key Laboratory of Frozen Soil Engineering Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences

To investigate the mechanical properties of ice-saturated frozen soil, a series of triaxial tests under various confining pressures（0.5 to 9.0 MPa） on ice-saturated frozen loess with ice content of 23.7% were carried out at a temperature-6 °C, and at 1.25 mm/min of loading rate. The triaxial tests include two loading modes, one with monotonic loading（i.e., triaxial compression）, and another with static cycle loading. The test results under triaxial compression show that the strength and deformation behaviors of ice-saturated frozen loess are affected by confining pressure. According to the test results of triaxial loading-unloading cycle test, the elastic modulus evolution with the number of cycles under different confining pressures are analyzed.

关键词： strength elastic modulus ice-saturated frozen loess confining pressure damage

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