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Numerical investigation of hydro-morphodynamic characteristics of a cascading failure of landslide dams

Journal of Mountain Science 2024年第6期21卷 1868-1885页

作者： ZHONG Qiming chen lingchun MEI Shengyao SHAN Yibo WU Hao ZHAO Kunpeng Department of Geotechnical Engineering Nanjing Hydraulic Research InstituteNanjing 210024China National Key Laboratory of Water Disaster Prevention Nanjing 210098China Key Laboratory of Reservoir and Dam Safety of the Ministry of Water Resources Nanjing 210029China

A cascading failure of landslide dams caused by strong earthquakes or torrential rains in mountainous river valleys can pose great threats to people’s lives,properties,and *** this study,based on the three-dimensional Reynoldsaveraged Navier-Stokes equations(RANS),the renormalization group(RNG)k-εturbulence model,suspended and bed load transport equations,and the instability discriminant formula of dam breach side slope,and the explicit finite volume method(FVM),a detailed numerical simulation model for calculating the hydro-morphodynamic characteristics of cascading dam breach process has been *** developed numerical model can simulate the breach hydrograph and the dam breach morphology evolution during the cascading failure process of landslide dams.A model test of the breaches of two cascading landslide dams has been used as the validation *** comparison of the calculated and measured results indicates that the breach hydrograph and the breach morphology evolution process of the upstream and downstream dams are generally consistent with each other,and the relative errors of the key breaching parameters,i.e.,the peak breach flow and the time to peak of each dam,are less than±5%.Further,the comparison of the breach hydrographs of the upstream and downstream dams shows that there is an amplification effect of the breach flood on the cascading landslide dam *** key parameters,i.e.,the distance between the upstream and the downstream dams,the river channel slope,and the downstream dam height,have been used to study the flood amplification *** parameter sensitivity analyses show that the peak breach flow at the downstream dam decreases with increasing distance between the upstream and the downstream dams,and the downstream dam ***,the peak breach flow at the downstream dam first increases and then decreases with steepening of the river channel *** the flood caused by the upstream dam failure flows to the

关键词： Cascading landslide dams Cascading dam failure process Detailed numerical simulation model Flood amplification effect Parameter sensitivity analyses

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Yolk free egg substitute improves the serum phospholipid profile of mice with metabolic syndrome based on lipidomic analysis

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Food Science and Human Wellness 2024年第1期13卷 482-493页

作者： Zhihui Yu lingyu Fan Fei Tai lixin Zhang Xiaoyu Zhang Yisheng chen College of Food Science and Engineering Shanxi Agricultural UniversityTaigu 030801China Insitute of Food Nutrition and Safety Shanxi Agricultural UniversityTaiyuan 030031China Shanxi Key Laboratory of Edible Fungi for Loess Plateau Taigu 030801China

In this study,the impacts of egg consumption on mice model of metabolic syndrome(Met S)were comparatively *** were divided into five groups(n=8):normal diet group(ND),high-fat diet group(HFD),HFD with whole egg group(WE),HFD with free-yolk egg substitute group(YFES),and HFD with lovastatin group(Lov).Main biochemical indexes and a non-targeted lipidomic analysis were employed to insight the lipid profile changes in *** was revealed that WE could significantly improve serum biochemical indexes by reducing body weight,low-density lipoprotein cholesterol(LDL-C)and total cholesterol(TC),while increasing high-density lipoprotein *** exhibited remarkably better performance in increasing phosphatidylglycerol and phosphatidic acids,while decreasing phosphatidylinositol than WE.A total of 50 differential lipids biomarkers tightly related to glycerophospholipids metabolism were screened *** C18:2 and C12:1,SM(d18:0/12:0),and SM(d18:1/14:1)were significantly upregulated in YFES compared to *** reduced expression of SREBP-1c and Cpt1a,while did not affect the expression of PPAR-α.Sphingomyelin biomarkers were positively related to the TC(|r|>0.6),while PPAR-αwas negatively correlated with triglyceride and LDL-C *** sum up,YFES attenuated HFD-induced Met S by improving the serum phospholipids,which account for its modulation of glycerophospholipid metabolism.

关键词： Metabolic syndrome Whole egg Yolk free egg substitute Serum lipidomics

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A Possible X-ray Quasi-periodic Oscillation in the Narrow-line Seyfert 1 Galaxy Mrk 142

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Research in Astronomy and Astrophysics 2024年第6期24卷 191-200页

作者： Xiao-Gu Zhong Jian-cheng Wang Yong-Yun chen Xiao-ling Yu College of Physics and Electronic Engineering Qujing Normal UniversityQujing 655011China Yunnan Observatories Chinese Academy of SciencesKunming 650216China

A possible quasi-periodic oscillation(QPO) at frequency 7.045 × 10^(-5) Hz is found in the narrow-line Seyfert 1galaxy Mrk 142 in the data of XMM-Newton collected on 2020 April *** find that the QPO signal is statistically significantly larger than the 5σ level and highly coherent with quality factor Q > 5 at the 0.3–10 keV band by using the method of the Lomb–Scargle Periodogram,the Weighted Wavelet Z-transform and the *** analyze the data in 0.3–0.6 keV,0.6–1 keV,1–3 keV and 3–10 keV energy bands,and find obvious QPO signals at 0.3–0.6 keV and 1–3 keV *** then analyze the time-average spectra and time variability at the QPO frequency of 7.045 × 10^(-5) Hz,and use a model to fit *** find that the QPO signal mainly comes from the X-ray hot corona.

关键词： X-rays:galaxies galaxies:Seyfert accretion accretion disks radiation mechanisms:general

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Interaction Between Ustilaginoidea virens and Rice and Its Sustainable Control

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Rice science 2024年第3期31卷 269-284页

作者： ZHANG Fengmin CAO Zhenzhen ZHENG Xin HE Yuntao chen Mingxue liN Xiaoyan Rice Product Quality Inspection&Supervision Testing Center of Ministry of Agriculture and Rural Affairs China National Rice Research InstituteHangzhou 310006China

Ustilaginoidea virens is a common rice pathogen that can easily lead to a decline in rice quality and the production of toxins pose potential risks to human *** this review,we present a comprehensive literature review of research since the discovery of rice false *** provide a comprehensive and,at times,critical overview of the main results and findings from related research,and propose future research ***,we delve into the interaction between *** and rice,including the regulation of transcription factors,the process of *** infecting rice panicles,and the plant immune response caused by rice *** that,we discuss the identification and characterization of mycotoxins produced by the pathogenic fungus,as well as strategies for disease *** emphasize the importance of comprehensive agricultural prevention and control methods for the sustainable management of *** knowledge will update our understanding of the interaction between *** and rice plants,offering a valuable perspective for those interested in ***.

关键词： rice false smut flower-specific infection mycotoxin food safety plant disease

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Stretchable and self-healing conductive fibers from hierarchical silver nanowires-assembled network

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Nano Research 2024年第2期17卷 763-770页

作者： Ying-Ying Wu Hong chen Fan Zhang Pan Guo Haili Qin Huai-Ping Cong Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering School of Chemistry and Chemical EngineeringHefei University of TechnologyHefei 230009China

Conductive fibers(CFs)with features of high conductivity,stretchability,self-healability,and electromechanical stability are key components of the increasingly popular wearable ***,since the lack of structural design of conductive network and interfacial interaction between soft polymer and conductive additives,it is still hard to enable CFs to meet above ***,we describe a facial drawing method from a hydrogel reservoir which is remolded into ultrathin and stretchable CFs with excellent multi-responsive *** hydrogel reservoir was fabricated in synergy of an ice-templating method and in situ polymerization using the assembled framework as a *** on the effective fabrication mechanism,the diameter of CFs could be well-tuned from 90 to 400μm by adjusting the dipping depth of the glass rod,accompanied with conductivity increased from 0.75 to 2.5 S/*** the hierarchical network structure was well maintained in the CFs,professional performances have been proved on the stretchability and electromechanical *** presence of massive hydrogen bonding and Ag–S bond enabled the CFs with excellent self-healability under the conditions of contact,electric field,and near infrared light,***,the CFs with high sensing property could be integrated into an advanced textile sensor through an effective healing-induced integration strategy,demonstrating its great potentials as superior two-dimensional(2D)electronic skins.

关键词： conductive fibers self-assembled silver nanowires Ag–S coordination self-healing flexible sensors

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Development of small molecule drugs targeting immune checkpoints

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Cancer Biology & Medicine 2024年第5期21卷 382-399页

作者： Luoyi chen Xinchen Zhao Xiaowei liu Yujie Ouyang Chuan Xu Ying Shi Department of Oncology Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengdu 610054China Institute for Breast Health Medicine State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China Acupuncture and Massage College Chengdu University of Traditional Chinese MedicineChengdu 611137China

Immune checkpoint inhibitors(ICIs)are used to relieve and refuel anti-tumor immunity by blocking the interaction,transcription,and translation of co-inhibitory immune checkpoints or degrading co-inhibitory immune *** of small molecule drugs or biological materials,especially antibody-based ICIs,are actively being studied and antibodies are currently widely ***,such as anti-tumor efficacy,poor membrane permeability,and unneglected tolerance issues of antibody-based ICIs,remain evident but are thought to be overcome by small molecule *** structural studies have broadened the scope of candidate immune checkpoint molecules,as well as innovative chemical *** way of comparison,small molecule drug-based ICIs represent superior oral bioavailability and favorable pharmacokinetic *** ongoing clinical trials are exploring the synergetic effect of ICIs and other therapeutic strategies based on multiple ICI functions,including immune regulation,anti-angiogenesis,and cell cycle *** this review we summarized the current progression of small molecule ICIs and the mechanism underlying immune checkpoint proteins,which will lay the foundation for further exploration.

关键词： Immune checkpoints small molecule drugs programmed death protein 1 CD47 signal-regulatory proteinα

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Optical two-dimensional coherent spectroscopy of excitons in transition-metal dichalcogenides

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Frontiers of physics 2024年第2期19卷 141-148页

作者： YanZuo chen ShaoGang Yu Tao Jiang XiaoJun liu XinBin cheng Di Huang State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsInnovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhan 430071China MOE Key Laboratory of Advanced Micro-Structured Materials Shanghai Frontiers Science Center of Digital OpticsInstitute of Precision Optical Engineeringand School of Physics Science and EngineeringTongji UniversityShanghai 200092China Shanghai Institute of Intelligent Science and Technology Tongji UniversityShanghai 200092China

Exciton physics in atomically thin transition-metal dichalcogenides(TMDCs)holds paramount importance for fundamental physics research and prospective ***,the experimental exploration of exciton physics,including excitonic coherence dynamics,exciton many-body interactions,and their optical properties,faces challenges stemming from factors such as spatial heterogeneity and intricate many-body *** this perspective,we elaborate upon how optical two-dimensional coherent spectroscopy(2DCS)emerges as an effective tool to tackle the challenges,and outline potential directions for gaining deeper insights into exciton physics in forthcoming experiments with the advancements in 2DCS techniques and new materials.

关键词： monolayer transition-metal dichalcogenides two-dimensional coherent spectroscopy

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A data-driven method for feature assessment of historical settlements: A case study of Northeast Hubei, China

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Frontiers of Architectural Research 2024年第2期13卷 387-405页

作者： Gangyi Tan Zhanxiang chen Jiangkun Zhu Kai Wang School of Architecture&Urban Planning Huazhong University of Science and TechnologyWuhan 430074China Hubei Engineering and Technology Research Center of Urbanization Wuhan 430074China Hubei Rural Construction Center Wuhan 430074China HUST Built Heritage Research Center Wuhan 430074China

Formulating criteria for the assessment system of historic settlements is challenging due to complex geographical conditions and evaluator knowledge limitations, leading to subjective bias in the assessment process. To address this issue, this study proposes a data-driven method for assessing the features of historical settlements to carry out scientific and refined assessment and result analysis. Focusing on Northeast Hubei as the study area, this paper selects 3 historical settlements for validation and analysis. The results of the study show that (1) the data-driven method expands the methodological chain of assessing historical settlement features, and improves the assessment efficiency and scientificity of the assessment results by applying it to the new assessment process;(2) Through comparing the assessment results of the validation cases and data samples, the study establishes a comprehensive quantitative ranking of the assessment of historical settlement features and identifies the main influencing factors, thus enhancing the precision of result analysis;(3) By comparing the resulting assessment framework with the current assessment system, this study confirms the advantages of the proposed framework in identifying nuanced features and aligning with geographical conditions, thereby verifying the effectiveness of the data-driven method.

关键词： Historical settlement Feature assessment Data-driven method Northeast Hubei

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高压大排量径向柱塞泵定子运动规律分析

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液压与气动 2024年第7期48卷 72-78页

作者：李少年程乐张子骞陈世豪杨龙涛兰州理工大学能源与动力工程学院甘肃兰州730050 兰州理工大学特种泵阀及流控系统教育部重点实验室甘肃兰州730050

为改善高压大排量径向柱塞泵定子-滑靴副摩擦状况,实现泵的精确变量,提出定子圆周方向非固定安装结构。通过滑靴柱塞组件力学特性分析,建立单个滑靴滑动摩擦力矩和11个滑靴摩擦合力矩,求解得到定子角速度变化曲线。结果表明,定子在滑靴... 详细信息

为改善高压大排量径向柱塞泵定子-滑靴副摩擦状况,实现泵的精确变量,提出定子圆周方向非固定安装结构。通过滑靴柱塞组件力学特性分析,建立单个滑靴滑动摩擦力矩和11个滑靴摩擦合力矩,求解得到定子角速度变化曲线。结果表明,定子在滑靴滑动摩擦力矩作用下能够运动,且排油区滑靴摩擦力矩大于吸油区滑靴摩擦力矩。径向柱塞泵正常工作后,定子角速度稳定在89.5~90.6 rad/s,呈周期变化,对定子运动起阻碍作用的滑靴个数为4、5交替变换。为高压大排量径向柱塞泵滑靴副设计、提高泵的性能提供一定参考。

关键词：径向柱塞泵滑靴定子摩擦力矩转角角速度

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基于局部区域强化的单目深度估计算法

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青岛大学学报（自然科学版） 2024年第1期37卷 39-44,51页

作者：王乐刚陈程立诏青岛大学计算机科学技术学院青岛266071 中国石油大学计算机科学技术学院青岛266555

针对深度估计场景中复杂纹理和复杂几何结构造成的物体边界扭曲、局部细节信息丢失等问题,提出基于局部区域强化的单目深度估计方法。首先,利用基于卷积神经网络的深度估计模型,得到低分辨率的图像;然后,引入显著目标检测模型,得到高分... 详细信息

针对深度估计场景中复杂纹理和复杂几何结构造成的物体边界扭曲、局部细节信息丢失等问题,提出基于局部区域强化的单目深度估计方法。首先,利用基于卷积神经网络的深度估计模型,得到低分辨率的图像;然后,引入显著目标检测模型,得到高分辨率的显著图像,监督生成深度图;最后将显著图与深度图融合,以此提高整个图像的深度估计精度。公共数据集上的实验结果表明,该方法可以显著提高单目深度估计的精度。

关键词：单目深度估计局部区域强化卷积神经网络深度学习

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