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Lufengpithecus inner ear provides evidence of a common locomotor repertoire ancestral to human bipedalism

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The Innovation 2024年第2期5卷 122-129页

作者： Yinan Zhang Xijun Ni Qiang Li Thomas Stidham Dan Lu Feng Gao Chi Zhang terry Harrison Key Laboratory of vertebrate Evolution and Human Origins Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China University of Chinese Academy of Sciences Beijing 100049China Yunnan Institute of Cultural Relics and Archeology Kunming 650118China Center for the Study of Human Origins Department of AnthropologyNew York UniversityNew YorkNY 10003USA

various lines of evidence have been used to infer the origin of human bipedalism,but the paucity of hominoid postcranial fossils and the diversity of inferred locomotor modes have tended to confound the reconstruction of ancestral *** of the bony labyrinth morphology of the inner ear of extinct and living hominoids provides independent evidence for inferring the evolution of hominoid locomotor *** computed tomography data and morphometric analyses of the Late Miocene ape Lufengpithecus indicate that it and other stem great apes possess labyrinths similar to one another and show that hominoids initially evolved from a positional repertoire that included orthogrady,below-branch forelimb suspension and progression,above-branch bipedalism,climbing,clambering,and leaping(hylobatid-like)to one that comprised above-branch quadrupedalism,below-branch forelimb suspension,vertical climbing,limited leaping,terrestrial quadrupedal running and walking,possibly with knuckle walking,and short bouts of bipedalism(chimpanzee-like).The bony labyrinth morphology of Lufengpithecus indicates that it probably conforms more closely to the last common ancestors of crown hominoids and hominids in its locomotor behavior than do other Miocene *** bipedalism evolved from this common archetypal Lufengpithecus-like locomotor *** low evolutionary rate of semicircular canal morphology suggests that Lufengpithecus experienced a relative stasis in locomotor behavior,probably due to the uplift of the Tibetan Plateau,which created a stable environment in the Miocene of southwestern China.

关键词： China probably uplift

From Hölder Continuous Solutions of 3D Incompressible Navier-Stokes Equations to No-Finite Time Blowup on [ 0,∞ ]

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Advances in Pure Mathematics 2024年第9期14卷 695-743页

作者： terry E. Moschandreou TvDSB London Ontario London Canada

This article gives a general model using specific periodic special functions, that is, degenerate elliptic Weierstrass P functions composed with the LambertW function, whose presence in the governing equations through the forcing terms simplify the periodic Navier Stokes equations (PNS) at the centers of arbitrary r balls of the 3-Torus. The continuity equation is satisfied together with spatially periodic boundary conditions. The yicomponent forcing terms consist of a function F as part of its expression that is arbitrarily small in an r ball where it is associated with a singular forcing expression both for inviscid and viscous cases. As a result, a significant simplification occurs with a v3(vifor all velocity components) only governing PDE resulting. The extension of three restricted subspaces in each of the principal directions in the Cartesian plane is shown as the Cartesian product ℋ=Jx,t×Jy,t×Jz,t. On each of these subspaces vi,i=1,2,3is continuous and there exists a linear independent subspace associated with the argument of the W function. Here the 3-Torus is built up from each compact segment of length 2R on each of the axes on the 3 principal directions x, y, and z. The form of the scaled velocities for non zero scaled δis related to the definition of the W function such that e−W(ξ)=W(ξ)ξwhere ξdepends on t and proportional to δ→0for infinite time t. The ratio Wξis equal to 1, making the limit δ→0finite and well defined. Considering r balls where the function F=(x−ai)2+(y−bi)2+(z−ci)2−ηset equal to −1e+rwhere r>0. is such that the forcing is singular at every distance r of centres of cubes each containing an r-ball. At the centre of the balls, the forcing is infinite. The main idea is that a system of singular initial value problems with infinite forcing is to be solved for where the velocities are shown to be locally Hölder continuous. It is proven that the limit of these singular problems shifts the finite time blowup time ti∗for first and higher deriv

关键词： Navier-Stokes Periodic Navier-Stokes Equations 3-Torus Periodic Ball Sphere Hölder Continuous Functions Uniqueness Angular velocity velocity in Terms of vorticity

Existence of a Hölder Continuous Extension on Embedded Balls of the 3-Torus for the Periodic Navier Stokes Equations

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Advances in Pure Mathematics 2024年第2期14卷 118-138页

作者： terry E. Moschandreou Intermediate Science and Mathematics TVDSB London Ontario Canada

This article gives a general model using specific periodic special functions, which is degenerate elliptic Weierstrass P functions whose presence in the governing equations through the forcing terms simplify the periodic Navier Stokes equations (PNS) at the centers of cells of the 3-Torus. Satisfying a divergence-free vector field and periodic boundary conditions respectively with a general spatio-temporal forcing term which is smooth and spatially periodic, the existence of solutions which have finite time singularities can occur starting with the first derivative and higher with respect to time. The existence of a subspace of the solution space where v3 is continuous and {C, y1, y12}, is linearly independent in the additive argument of the solution in terms of the Lambert W function, (y12=y2, C∈R) together with the condition v2=-2y1v1. On this subspace, the Biot Savart Law holds exactly [see Section 2 (Equation (13))]. Also on this subspace, an expression X (part of PNS equations) vanishes which contains all the expressions in derivatives of v1 and v2 and the forcing terms in the plane which are related as with the cancellation of all such terms in governing PDE. The y3 component forcing term is arbitrarily small in ε ball where Weierstrass P functions touch the center of the ball both for inviscid and viscous cases. As a result, a significant simplification occurs with a v3 only governing PDE resulting. With viscosity present as v changes from zero to the fully viscous case at v =1 the solution for v3 reaches a peak in the third component y3. Consequently, there exists a dipole which is not centered at the center of the cell of the Lattice. Hence since the dipole by definition has an equal in magnitude positive and negative peak in y3, then the dipole Riemann cut-off surface is c

关键词： Navier-Stokes PNS 3-Torus Periodic Ball Sphere Hölder Continuous Riemann-Surface Uniqueness

Drug-Drug Interactions in Patients with Breast Cancer

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Journal of Biosciences and Medicines 2024年第9期12卷 113-131页

作者： Balaram Gudapati terry Oroszi Department of Pharmacology & Toxicology Boonshoft School of Medicine Washington State University (WSU) Pullman USA

The research paper investigates the intricate landscape of drug-drug interactions (DDIs) within the context of breast cancer treatment, with a particular focus on the elderly population and the use of complementary and alternative medicine (CAM). The study underscores the heightened susceptibility of elderly patients to DDIs due to the prevalence of polypharmacy and the widespread utilization of CAM among breast cancer patients. The potential ramifications of DDIs, encompassing adverse drug events and diminished treatment efficacy, are elucidated. The paper accentuates the imperative for healthcare providers to comprehensively understand both conventional and CAM therapies, enabling them to provide patients with informed guidance regarding safe and efficacious treatment options, culminating in enhanced patient outcomes.

关键词： Breast Cancer Drug-Drug Interactions Polypharmacy Side Effects Anti-Cancer Drug Failure Complementary and Alternative Medicine

Active and passive modulation of solar light transmittance in a uniquely multifunctional dual-band single molecule for smart window applications

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Journal of Energy Chemistry 2024年第1期88卷 293-305,I0007页

作者： Pooja v.Chavan Pramod v.Rathod Joohyung Lee Sergei v.Kostjuk Hern Kim Department of Energy Science and Technology Environmental Waste Recycle InstituteMyongji UniversityYonginGyeonggi-do 17058Republic of Korea Department of Chemical Engineering Myongji UniversityYonginGyeonggi-do 17058Republic of Korea Research Institute for Physical Chemical Problems of the Belarusian State University MinskBelarus

Functional materials may change color by heat and electricity separately or simultaneously in smart *** materials have not only demonstrated remarkable potential in the modulation of solar radiation but are also leading to the development of indoor environments that are more comfortable and conducive to improving individuals'quality of ***,dual-responsive materials have not received ample research attention due to economic and technological *** a consequence,the broader utilization of smart windows faces *** address this new generational multistimulus responsive chromic materials,our group has adopted a developmental strategy to create a poly(NIPAM)n-Hv as a switchable material by anchoring active viologen(Hv)onto a phase-changing poly(NIPAM)n-based smart material for better utility and *** constructed smart windows facilitate individualistic reversible switching,from a highly transparent state to an opaque state(thermochromic)and a red state(electrochromic),as well as facilitate a simultaneous dual-stimuli response reversible switching from a clear transparent state to a fully opaque(thermochromic)and orange(electrochromic)*** privacy can be attained in smart windows designed for exclusive settings by achieving zero *** unique chromic mode operates independently and modulates visible and near-infrared(NIR)light in a distinct ***,these smart windows with thermal and electric dual-stimuli responsiveness demonstrate remarkable heat regulation capabilities,rendering them highly attractive for applications in building facades,energy harvesting,privacy protection,and color display.

关键词： Smart windows Thermochromism Electrochromism Energy saving Dual-responsive material

Storylines of family medicine Ⅷ:clinical approaches

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Family Medicine and Community Health 2024年第S3期12卷 70-78页

作者： William B ventres Leslie A Stone lauren E Gibson-Oliver Elizabeth Kyle Meehan Mari A Ricker David Loxterkamp Stacy A Ogbeide Frank v deGruy Megan R Mahoney Steven Lin Clare MacRae Stewart W Mercer Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family and Community Medicine The University of Arizona College of Medicine-TucsonTucsonArizonaUSA Bucksport Regional Health Center BucksportMaineUSA Family and Community Medicine UT Health San Antonio Long School of MedicineSan AntonioTexasUSA Eugene S.Farley Jr.Health Policy CenterUniversity of Colorado Anschutz Medical Campus School of MedicineAuroraColoradoUSA Family and Community Medicine University of California San Francisco School of MedicineSan FranciscoCaliforniaUSA Division of Primary Care and Population Health Stanford MedicinePalo AltoCaliforniaUSA Usher Institute Edinburgh Medical SchoolUniversity of EdinburghEdinburghUK

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅷ:clinical approaches’,authors address the following themes:‘Evaluation,diagnosis and managementⅠ—toward a working diagnosis’,‘Evaluation,diagnosis and managementⅡ—process steps’,‘Interweaving integrative medicine and family medicine’,‘Halfway—the art of clinical judgment’,‘Seamless integration in family medicine—team-based care’,‘Technology—uncovering stories from noise’and‘Caring for patients with multiple long-term conditions’.May readers recognise in these essays the uniqueness of a family medicine approach to care.

关键词： uniqueness dimensions illustration

Unravelling-based (auto)control of back-action in atomic Bose–Einstein condensate

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Frontiers of physics 2024年第4期19卷 287-295页

作者： v.A.Tomilin L.v.Il’ichov Institute of Automation and Electrometry SB RAS 630090 NovosibirskRussia

We present a novel feedback control method for quantum *** does not affect the controlled system ***,it controls the unravelling of the quantum channel of interaction between the system and its *** interaction can be represented as a history of *** their informational content is changed,their back-action on the system is also *** action is trigged by the events,thus granting the system the degree of control over its own *** efficiency of the proposed scheme is demonstrated on the example of two-mode atomic Bose-Einstein condensate,with one of its modes subject to phase-contrast imaging in a Mach–Zehnder *** histories of photocounts in the output channels of the interferometer are used for *** capabilities of state engineering are studied for different settings of the feedback loop and different numbers of events in the recorded histories.

关键词： quantum feedback control quantum measurements twomode Bose-Einstein condensates

Photoluminescence,structural and antibacterial properties of co-dopedβ-Ca_(3)(PO_(4))_(2)-type phosphates Ca_(8)CuRE(PO_(4))_(7)(RE=Eu-Er)

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Journal of Rare Earths 2024年第9期42卷 1658-1668,I0002页

作者： Ivan v.Nikiforov Ekaterina v.Iliin Bogdan I.Lazoryak Sergey M.Aksenov Pavel v.Slukin Dina v.Deyneko Department of Chemistry Lomonosov Moscow State University119991MoscowRussia Laboratory of Arctic Mineralogy and Material Sciences Kola Science CentreRussian Academy of Sciences184209ApatityRussia Geological Institute Kola Science CentreRussian Academy of Sciences184209ApatityRussia State Scientific Center of Applied Microbiology and Biotechnology of Rospotrebnadzor 24 Block A142279ObolenskRussia

Novel Ca_(8)CuRE(PO_(4))_(7)where RE^(3+)=Eu^(3+),Tb^(3+),Dy^(3+),Ho^(3+)and Er^(3+)were synthesized by a solid-state method in *** structures of the samples were characterized by powder X-ray diffraction using Rietveld refinement to determine the occupation of crystal *** samples are found to have a centrosymmetric structure with space group R3c,as shown by dielectric *** synthesized Ca_(8)CuRE(PO_(4))_(7)samples have multifunctional *** Cu^(2+)ions provide antibacterial properties,while the rare earth elements ions exhibit luminescence properties,and theβ-Ca_3(PO_(4))_(2)-type host is *** photoluminescence properties of RE^(3+)ions were studied and compared with other simmilar Ca_(8)MRE(PO_(4))_(7)phosphates,where M is a divalent *** photoluminescence intensity quenching in terms of energy transfer from RE^(3+)to Cu^(2+)is *** bioactive properties were studied in relation to antibacterial activity against *** and *** syntesized Ca_(8)CuRE(PO_(4))_(7)samples demonstrate very high and stable inhibition of bacteria *** correlation between crystal structure and properties is *** combining multiple approaches to the directio nal design of such materials,several important properties within a single chemical compound to achieve biovisualization and bioactive properties simultaneously can be combined.

关键词： β-Ca_(3)(PO_(4))_(2) Whitlockite-type structure Bioactive phosphates TCP Photoluminescence Rare earths

The Radcliffe Wave Parameters from Data on Open Star Clusters

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Research in Astronomy and Astrophysics 2024年第3期24卷 106-109页

作者： v.v.Bobylev A.T.Bajkova Pulkovo Astronomical Observatory St-Petersburg 196140Russia

A spectral analysis of the vertical positions and velocities of 374 open star clusters(OSCs)was carried *** took these OSCs from the Hunt and Reffert catalog;they have an average age of about 10 million years,and are located on the galactic plane XY in a narrow zone inclined by 25°to the galactic axis *** following estimates of the parameters of the Radcliffe wave were obtained:(a)the maximum value in periodic perturbations of vertical coordinates Z_(max)=92±10pc with the wavelength of these perturbations λ_(z)=4.82±0.09 kpc;(b)the maximum value of the velocity of vertical disturbances Wmax=4.36±0.12km s^(-1) with disturbance wavelengthλ_(W)=1.78±0.02 *** that the results of the vertical velocity analysis are first-class in accuracy and completely new.

关键词： (Galaxy) local interstellar matter-Galaxy structure-(Galaxy) solar neighborhood