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The first pterosaur 3-D egg:Implications for Pterodaustro guinazui nesting strategies,an Albian filter feeder pterosaur from central Argentina

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Geoscience Frontiers 2014年第6期5卷 759-765页

作者： Gerald Grellet-Tinner Michael B.Thompson Lucas E.Fiorelli Eloísa Argaaraz laura Codorniú E.Martín Hechenleitner Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja (CRILAR-COnICET) Entre Ríos y Mendoza s/nAnillaco5301 La RiojaArgentina Orcas Island Historical Museums USA School of Biological Sciences (A08) University of SydneyNSW 2006Australia COnICET Argentina Centro de Investigaciones Paleobiológicas (CIPAL) Universidad Nacional de CórdobaAv.Vélez Sarsfield 2995000 CórdobaArgentina Departamento de Geología Universidad Nacional de San LuisSan LuisArgentina

The increasing number of fossil pterosaur eggs sheds light on nesting environments and breeding be- haviors of these extinct flying reptiles. Here we report the first partial three-dimensional egg of the pterosaur, Pteroduustro guinazui, from central Argentina. The specimen was discovered from the same Albian deposits as the exceptional R guinazui embryo described in 2004. Microscopic characterizations indicate a pristine preservation of the 50 Bm thick calcium carbonate, which differs significantly from the soft shell of Chinese pterosaur eggs. Estimate of the eggshell conductance implies that the nest had a minimum moisture content of 75%. This moisture estimate, combined with geological and taphonomical data, suggests that P. guinazui may have adopted a nesting strategy similar to those of grebes and flamingos rather than being buried on land, as previously hypothesized. Moreover, our results demon- strate that the nesting paleoenvironment of this pterosaur species was closely linked to a mesohaline lacustrine ecosystem in a basin governed by regional tectonic subsidence, a setting characteristic for the feeding and reproduction of modern flamingos.

关键词： Pterosaur fossil eggsPterosaur eggshellPterodaustro guinazuiGondwanaEggshell conductance

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Phenotyping Key Fruit Quality Traits in Olive Using RGB Images and Back Propagation neural networks

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Plant Phenomics 2023年第3期5卷 484-500页

作者： Giuseppe Montanaro Angelo Petrozza laura Rustioni Francesco Cellini Vitale nuzzo Università degli Studi della Basilicata 85100 PotenzaItaly ALSIA Agenzia Lucana Sviluppo Innovazione in AgricolturaMetapontum Agrobios Research Center75010 MetapontoItaly Department of Biological and Environmental Sciences and Technologies University of SalentoLecceItaly

To predict oil and phenol concentrations in olive fruit,the combination of back propagation neural networks(BPnns)and contact-less plant phenotyping techniques was employed to retrieve RGB image-based digital proxies of oil and phenol *** of cultivars(×3)differing in ripening time were sampled(~10-day interval,×2 years),pictured and analyzed for phenol and oil *** to this,fruit samples were pictured and images were segmented to extract the red(R),green(G),and blue(B)mean pixel values that were rearranged in 35 RGB-based colorimetric *** BPnns were designed using as input variables(a)the original 35 RGB indexes,(b)the scores of principal components after a principal component analysis(PCA)pre-processing of those indexes,and(c)a reduced number(28)of the RGB indexes achieved after a sparse *** results show that the predictions reached the highest mean R^(2) values ranging from 0.87 to 0.95(oil)and from 0.81 to 0.90(phenols)across the *** addition to the R^(2),other performance metrics were calculated(root mean squared error and mean absolute error)and combined into a general performance indicator(GPI).The resulting rank of the GPI suggests that a BPnn with a specific topology might be designed for cultivars grouped according to their ripening *** present study documented that an RGB-based image phenotyping can effectively predict key quality traits in olive fruit supporting the developing olive sector within a digital agriculture domain.

关键词： Image image supporting

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Clinical Parameters in the First 5 Minutes after Birth Have a Predictive Value for Survival of Extremely Preterm Infants

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Maternal-Fetal Medicine 2023年第4期5卷 244-247页

作者： laura Torrejón-Rodríguez Álvaro Solaz-García Inmaculada Lara-Cantón Alejandro Pinilla-González Marta Aguar Máximo Vento Division of neonatology University and Polytechnic Hospital La Fe(HULAFE)Valencia 46026Spain neonatal Research Group Instituto de Investigación Sanitaria La Fe(IISLAFE)Valencia 46026Spain

Extreme preterm infants(60%)and lower(<30%)initial FiO_(2).Recent evidence and meta-analyses have underscored the predictive value for survival and/or relevant clinical outcomes of the Apgar score and the achievement ... 详细信息

Extreme preterm infants(n)often require positive pressure ventilation with oxygen during postnatal stabilization in the delivery *** date,optimal inspired fraction of oxygen(FiO_(2))still represents a conundrum in newborn care oscillating between higher(>60%)and lower(nitial FiO_(2).Recent evidence and meta-analyses have underscored the predictive value for survival and/or relevant clinical outcomes of the Apgar score and the achievement of arterial oxygen saturation measured by pulse oximetry≥85%at 5 minutes after *** clinical trials comparing higher versus lower initial FiO_(2)have been launched aiming to optimize postnatal stabilization of extreme preterm while avoiding adverse effects of hypoxemia or hyperoxemia.

关键词： Extreme preterm Postnatal stabilization Oxygen saturation Heart rate Inspired fraction of oxygen Apgar score

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Simultaneous pars plana vitrectomy,panretinal photocoagulation,cryotherapy,and Ahmed valve implantation for neovascular glaucoma

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International Journal of Ophthalmology(English edition) 2021年第9期14卷 1396-1401页

作者： Carolina Bernal-Morales Marina Dotti-Boada Alvaro Olate-Perez Manuel J.navarro-Angulo laura Pelegrín Marc Figueras-Roca Institut Clínic d’Oftalmologia(ICOF) Hospital ClínicBarcelona 08028Spain August Pi i Sunyer Biomedical Research Institute(IDIBAPS) Barcelona 08028Spain

AIM:To describe and evaluate the efficacy of Ahmed glaucoma valve implantation(AGV)combined with pars plana vitrectomy(PPV)in a single surgical act for the treatment of advanced neovascular glaucoma(nVG).METHODS:Retrospective observational case series included 51 eyes from 50 patients with severe nVG treated with PPV,AGV,and panretinal photocoagulation and/or cryotherapy in a single surgical act during a 13-year period(2005-2018).Preoperative,intraoperative and postoperative data at day 1 and months 1,3,6,21,and 24 were systematically *** of surgical success was stablished at IOP between 6 and 21 mm Hg with or without topical ***:Main indications for surgery were nVG secondary to proliferative diabetic retinopathy(39.2%)and central retinal vein occlusion(37.3%).Mean(±SD)preoperative IOP was 42.0±11.2 mm Hg decreasing to 15.5±7.1 mm Hg at 12 mo and 15.8±9.1 mm Hg at 24 mo of follow *** incidence of success of IOP control was 76.0%at first postoperative month,reaching 88.3%at 6 *** of successful IOP control at long term was 74.4%at 12 mo and 71.4%at 24 *** evisceration for unsuccessful nVG management was required in 1 case(2.0%).COnCLUSIOn:Combination of AGV implantation and PPV in a single act may be a suitable option for severe forms of nVG in a case-by-case basis for effective IOP control and a complete panretinal photocoagulation.

关键词： neovascular glaucoma Ahmed valve pars plana vitrectomy panretinal photocoagulation cryotherapy

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Diversity of Saxicolous Lichens along an Aridity Gradient in Central México

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Phyton-International Journal of Experimental Botany 2022年第4期91卷 827-840页

作者： JoséCarmen Soto-Correa Abraham Saldaña-Vega Víctor Hugo Cambrón-Sandoval laura Concostrina-Zubiri Mariela Gómez-Romero Facultad de Ciencias naturales Universidad Autónoma de QuerétaroQuerétaro73230México Departamento de Biología y Geología Física y Química Inorgánica Tulipán s/nUniversidad Rey Juan CarlosMóstolesMadrid28933España Cátedra COnACYT–Facultad de Biología Universidad Michoacana de San Nicolás de HidalgoMoreliaMichoacán58030México

Lichens are symbiotic organisms that comprise a fungus and a photosynthetic partner wich are recognized as a good indicator of climate ***,our understanding of how aridity affects the diversity of saxicolous lichens in drylands is still *** evaluate the relationship between saxicolous lichen diversity and aridity in a central México dryland,a geographical transect was established of 100 km to build an aridity gradient in the semiarid zone of the State of Querétaro,Mexico,comprising ten sampling sites with a 10 km *** richness,abundance and diversity of soil lichen species were recorded using two sampling methods:the quadrat-intercept and the line-intercept method,to compare their performance in assessing soil lichen diversity in *** number of species and Shannon diversity of saxicolous lichens were higher at intermediate values of the aridity index(AI=0.10-0.34).Quadrat intercept and point intercept methods gave quite similar results,which means that the selected method does not influence the results in a significant *** study confirms the role of saxicolous lichens as climate change indicators and reveals the importance of the sampling method selection in the evaluation of different parameters of soil lichen diversity in drylands.

关键词： Climate change drylands ecological indicators environmental stress precipitation temperature

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Counter-regulatory phosphatases TnAP and nPP1 temporally regulate tooth root cementogenesis

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International Journal of Oral Science 2015年第1期7卷 27-41页

作者： laura E Zweifler Mudita K Patel Francisco H nociti Jr Helen F Wimer Jose L Milln Martha J Somerman Brian L Foster national Institute of Arthritis and Musculoskeletal and Skin Diseases (nIAMS) National Institutes of Health (NIH) Department of Prosthodontics and Periodontics Division of Periodontics School of Dentistry Campinas State University Department of Vertebrate Zoology National Museum of Natural History Smithsonian Institution Sanford Children’s Health Research Center Sanford-Burnham Medical Research Institute

Cementum is critical for anchoring the insertion of periodontal ligament fibers to the tooth root. Several aspects of cementogenesis remain unclear, including differences between acellular cementum and cellular cementum, and between cementum and bone. Biomineralization is regulated by the ratio of inorganic phosphate （Pi） to mineral inhibitor pyrophosphate （PPi）, where local Pi and PPi concentrations are controlled by phosphatases including tissue-nonspecific alkaline phosphatase （TnAP） and ectonucleotide pyrophosphatase/phosphodiesterase 1 （nPP1）. The focus of this study was to define the roles of these phosphatases in cementogenesis. TnAP was associated with earliest cementoblasts near forming acellular and cellular cementum. With loss of TnAP in the Alpl null mouse, acellular cementum was inhibited, while cellular cementum production increased, albeit as hypomineralized cementoid. In contrast, nPP1 was detected in cementoblasts after acellular cementum formation, and at low levels around cellular cementum. Loss of nPP1 in the Enppl null mouse increased acellular cementum, with little effect on cellular cementum. Developmental patterns were recapitulated in a mouse model for acellular cementum regeneration, with early TnAP expression and later nPP1 expression. In vitro, cementoblasts expressed Alpl gene/protein early, whereas Enppl gene/protein expression was significantly induced only under mineralization conditions. These patterns were confirmed in human teeth, including widespread TnAP, and nPP1 restricted to cementoblasts lining acellular cementum. These studies suggest that early TnAP expression creates a low PPi environment promoting acellular cementum initiation, while later nPP1 expression increases PPi, restricting acellular cementum apposition. Alterations in PPi have little effect on cellular cementum formation, though matrix mineralization is affected.

关键词： cementum bone ectonucleotide pyrophosphatase phosphodiesterase 1 periodontal ligament progressive ankylosis protein tissue-nonspecific aJkalJne phosphatase

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Plasticity of callosal neurons in the contralesional cortex following traumatic brain injury

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neural Regeneration Research 2023年第6期18卷 1257-1258页

作者： Alexandra Chovsepian laura Empl Florence M.Bareyre Institute of Clinical neuroimmunology Biomedical Building and Clinic of the Ludwig-Maximilians Universität MünchenMunichGermany

Traumatic brain injury(TBI) represents a significant cause of disability *** creates a vast array of damaging macro-and microscopic changes in the affected brain area(s),ranging from neuronal cell death,changes in structural spine integrity and dynamics to axonal injury and ove rall neuronal circuit disruption,ultimately leading to functional and cognitive deficits in both humans and animal models(n udo,2013).

关键词： injury traumatic cortex

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Completion thyroidectomy:is timing important for transcervical and remote access approaches?

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World Journal of Otorhinolaryngology-Head and neck Surgery 2020年第3期6卷 165-170页

作者： Juan Pablo Duenas Carlos Simon Duque laura Cristancho Manuela Mendez Hospital Pablo Tobon Uribe Instituto de Cancerologia IDC Las AmericasClfnica Universitaria BolivarianaClinica el Rosario Sede el Tesoro(CLID)MedellinColombia Universidad Militor nueva Granada BogotaDCColombia Universidad CES MedellinColombia Hospital Pablo Tobon Uribe Clfnica Las AmericasMedellinColombia

Completion thyroidectomy(CT)is employed after lobectomy when histopathological results mandates total removal of the gland as in case of well differentiated thyroid carcinoma(DTC).It is also employed as a second stage thyroid surgery when unfavorable events occur as in recurrent laryngeal nerve injury or when the surgeon finds out the case is beyond his/her expertise in an attempt to protect the contralateral side and allowing time for recovery or for an expert surgeon to help.

关键词： Completion thyroidectomy Total thyroidectomy Complications nerve monitoring

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Toric人工晶状体在合并高度角膜散光白内障中的应用（英文）

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国际眼科杂志 2018年第2期18卷 213-218页

作者： Irene Simo Rafael Freiria laura Remón Marina Salud医院眼科西班牙德尼亚03700 萨拉戈萨大学应用物理学系西班牙萨拉戈萨50009

目的:评估Bi-Flex toric人工晶状体在合并散光的白内障中的应用。方法:回顾性研究包括16例22眼合并2.50D以上散光的白内障患者。测量了术前与术后的裸眼视力、最佳矫正视力、客观及主观验光、角膜散光仪和角膜地形图测量的散光值。术后... 详细信息

目的:评估Bi-Flex toric人工晶状体在合并散光的白内障中的应用。方法:回顾性研究包括16例22眼合并2.50D以上散光的白内障患者。测量了术前与术后的裸眼视力、最佳矫正视力、客观及主观验光、角膜散光仪和角膜地形图测量的散光值。术后人工晶状体屈光轴位置使用向量进行分析。结果:术后,主观验光散光值从4.05D±1.53D显著降低至1.35D±0.86D,(P0.05)。结论:对于合并大于2.50D散光的白内障患者,Bi-Flex toric人工晶状体植入是安全有效的治疗方法。

关键词： toric人工晶状体散光稳定性向量分析

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Downregulation of the Basic Peroxidase Isoenzyme from Zinnia elegans by Gibberellic Acid

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Journal of Integrative Plant Biology 2010年第2期52卷 244-251页

作者： María Josefa López núez-Flores Jorge Gutirrez laura V.Gómez-Ros Esther novo Uzal Mariana Sottomayor Alfonso Ros Barceló Department of Plant Biology University of MurciaE-30100MurciaSpain Department of Plant Biology University of La CoruaE-15071La CorunaSpain IBMC University of Porto4150 PortoPortugal

Hypocotyl formation during the epigeal germination of seedlings is under strict hormonal regulation. In a 3 d old Zinnia elegans seedling system, gibberellic acid （GA3） exerts an opposite effect to that exerted by light on hypocotyl photomorphogenesis because GAz promotes an etiolated-like growth with an inhibition of radial （secondary） growth. For this reason, the effect of GA3 on the basic peroxidase isoenzyme from Z. elegans （ZePrx）, an enzyme involved in hypocotyl lignin biosynthesis, was studied. The results showed that GA3 reduces ZePrx activity, similarly to the way in which it reduces seedling secondary growth. This hormonal response is supported by the analysis of the ZePrx promoter, which contains four types of GA3-responsive ***： the W Box/O2S; the Pyr Box; the GARE; and the Amy Box. Taken together, these results suggest that ZePrx is directly regulated by GA3, with this effect matching the inhibitory effect of GA on the hypocotyl secondary growth.

关键词： GA Downregulation of the Basic Peroxidase Isoenzyme from Zinnia elegans by Gibberellic Acid cis Figure

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