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Evaluation of the Finnish Diabetes Risk Score to predict type 2 diabetes mellitus in a Colombian population: A longitudinal observational study

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World Journal of Diabetes 2015年第17期6卷 1337-1344页

作者： Diego Gomez-Arbelaez laura alvarado-jurado Miguel Ayala-Castillo Leonardo Forero-Naranjo Paul Anthony Camacho Patricio Lopez-Jaramillo Dirección de Investigaciones Clínica de Síndrome Metabólico Prediabetes y Diabetes Fundación Oftalmológica de Santander - FOSCAL Instituto de Investigaciones MASIRA Facultad de Medicina Universidad de Santander - UDES División de Endocrinología Escuela de Medicina Universidad de Santiago de Compostela Escuela de Medicina Universidad Autónoma de Bucaramanga

AIM: To assess the performance of the Finnish Diabetes Risk Score(FINDRISC) questionnaire for detecting and predicting type 2 diabetes mellitus(DM2) in a Colombian ***: This is a longitudinal observational study conducted in Floridablanca, Colombia. Adult subjects(age ≥ 35 years) without known diabetes, were included. A modified version of FINDRISC was completed, and the glycemia values from all the subjects were collected from the hospital's database. Firstly, a cross-sectional analysis was performed and then, the subsample of prediabetic participants was followed for diabetes incidence. RESULTS: A total of 772 subjects were suitable for the study. The overall prevalence of undiagnosed DM2 was 2.59%, and the incidence of DM2 among the prediabetic participants was 7.5 per 100 person-years after a total of 265257 person-years follow-up. The FINDRISC at baseline was significantly associated with undiagnosed and incident DM2. The area under receiver operating characteristics curve of the FINDRISC score for detecting undiagnosed DM2 in both men and women was 0.7477 and 0.7175, respectively; and for predicting the incidence of DM2 among prediabetics was 71.99% in men and 67.74% in women. CONCLUSION: The FINDRISC questionnaire is a useful screening tool to identify cross-sectionally unknown DM2 and to predict the incidence of DM2 among prediabetics in the Colombian population.

关键词： Finnish diabetes risk score Type 2 diabetes mellit

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The Phenols of the Genus <i>Agave</i>(Agavaceae)

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Journal of Biomaterials and Nanobiotechnology 2013年第3期4卷 9-16页

作者： Norma Almaraz-Abarca Eli Amanda Delgado-alvarado José Antonio ávila-Reyes José Natividad Uribe-Soto laura Silvia González-Valdez Centro Interdisciplinario de Investigación para el Desarrollo Integral Regional Unidad Durango Instituto Politécnico Nacional Durango Dgo México

A review is presented about the studies that have been carried out on the phenolic composition of the species of the genus Agave in order to show which species of the genus has been analyzed, what is the potential of the species of Agave as source of phenolics with important biological activities, and what is the significance of the phenolic profiles as chemotaxonomic markers in the genus. The results of the analysis of a dozen of Agave species reveal an important richness of phenolic compounds, including flavonoids, homoisoflavonoids, and phenolic acids, and a broad diversity of biological activities associated to those compounds, as antioxidant, antibacterial, antifungal, antinematod, and immunomodulatory capabilities. The phenols of Agave also have a major potential as specific chemotaxonomic markers.

关键词： Genus Agave Phenol Profiles Homoisoflavanoids Biological Activity Chemotaxonomic Markers

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Effect of Gamma Irradiation and Selection with Fungus Filtrate(Rhizoctonia solani Kuhn)on the in Vitro Culture of Common Bean(Phaseolus vulgaris)

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American Journal of Plant Sciences 2015年第16期6卷 2672-2685页

作者： laura Y.Solís-Ramos Marta Valdez-Melara Ricardo alvarado-Barrantes Floribeth Mora-Umana Eduardo Hernández-Jiménez Natalia Barboza-Vargas Pilar Ramírez-Fonseca Plant Biotechnology & Genetic Transformation School of Biology University of Costa Rica San Pedro Costa Rica School of Statistic University of Costa Rica San Pedro Costa Rica Interagency Cooperation Agreement between the Research Center for Cellular and Molecular Biology (CIBCM) University of Costa Rica and the Phytosanitary Agency of the Ministry of Agriculture and Livestock (MAG) San José Costa Rica Research Center for Cellular and Molecular Biology (CIBCM) University of Costa Rica San Pedro Costa Rica

The present investigation was undertaken to study the effect of gamma irradiation (dose from 10 to 100 Gy) and in vitro selection with fungus filtrate as selecting agent (concentration from 20% to 100%) on the susceptibility of the common bean to Rhizoctonia solani. The best results were found with a dose of 20 Gy or a concentration of 20% of fungus filtrate applied separately. These conditions were used to evaluate the combined effect of both approaches in a second experiment. The combined effect of irradiation and then selection adversely affected growth (height and roots) and survival of the in vitro plants. It may not be necessary to combine the variation generated by irradiation with the selection technique. For future assays we propose the application of: 1) gamma radiation, thereby inducing not only mutants with pathogen resistance, but also with other agronomic traits of interest. Later in the subculture MV4 potential fungus-resistant mutants will be evaluated in the field;or 2) selection pressure using fungus filtrate during three subcultures, which may be sufficient to induce the variation necessary to obtain in vitro plants resistant to fungus.

关键词： Mutagenesis Radiosensitivity In Vitro Selection Rhizoctonia Common Bean

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迈阿密大学学生活动中心

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建筑技艺 2009年第10期15卷 70-75页

作者： Arquitectonica Bernardo Fort Brescia Laurinda Spear Alfonso jurado Isamu Kanda Katia Robreno laura Gilmore Tara-Keens Douglas FAIA iiiK Studio Kurf Ltd. Konstruct West Partners

迈阿密大学学生活动中心将位于奥西奥拉湖沿岸，从校园门口的米勒大道延伸到斯坦福街的莱登大学中心。校园核心部分的综合体将为数千名学生、教师和工作人员服务，使学生个人与社团组织结成一个整体。

关键词：学生活动中心迈阿密大学社团组织工作人员使用面积综合体工作区

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