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Associations between health-related fitness and patient-reported symptoms in newly diagnosed breast cancer patients

journal of Sport and Health Science 2024年第6期13卷 851-862页

作者： Ki-Yong An Fernanda Z.Arthuso Myriam Filion Spencer j.Allen Stephanie M.Ntoukas Gordon j.Bell.j.ssica McNeil Qinggang Wang Margaret l.McNeely jeff K.Vallance lin Yang S.Nicole Culos-Reed leanne Dickau john R.Mackey Christine M.Friedenreich Kerry S.Courneya Faculty of Kinesiology Sportand RecreationCollege of Health SciencesUniversity of AlbertaEdmonton T6G 2H9Canada Department of Kinesiology School of Health and Human SciencesUniversity of North Carolina at GreensboroGreensboroNC 27412USA Department of Cancer Epidemiology and Prevention Research Cancer Care AlbertaAlberta Health ServicesCalgary T2S 3C3Canada Faculty of Rehabilitation Medicine University of AlbertaEdmonton T6G 2H9Canada Faculty of Health Disciplines Athabasca UniversityAthabasca T9S 3A3Canada Department of Oncology Cumming School of MedicineUniversity of CalgaryCalgary T2N 4N1Canada Faculty of Kinesiology University of CalgaryCalgary T2N 1N4Canada Faculty of Medicine and Dentistry University of AlbertaEdmonton T6G 2H9Canada

Background:Newly diagnosed breast cancer patients experience symptoms that may affect their quality of life,treatment outcomes,and *** and managing breast cancer-related symptoms soon after diagnosis is *** purpose of this study was to investigate the associations between health-related fitness(HRF)and patient-reported symptoms in newly diagnosed breast cancer ***:This study utilized baseline data from the Alberta Moving Beyond Breast Cancer Cohort Study that were collected within 90 days of *** measures included peak cardiopulmonary fitness(peak volume of oxygen consumption(VO_(2peak))),maximal muscular strength and endurance,flexibility,and body *** measures included depression,sleep quality,and *** multivariable logistic regression was performed for ***:Of 1458 participants,51.5%reported poor sleep quality,26.5%reported significant fatigue,and 10.4%reported moderate *** multivariable-adjusted models,lower relative VO_(2peak)was independently associated with a greater likelihood of all symptom measures,including moderate depression(pleep quality(p=0.009),significant fatigue(p=0.008),any symptom(pltiple symptoms(pld associations with all symptom measures such that all 3 lower quartiles exhibited similar elevated risk compared to the highest *** strength of the threshold associations varied by the symptom measure with odds ratios ranging from-1.5 for poor sleep quality to-3.0 for moderate depression and multiple ***,lower relative upper body muscular endurance was also independently associated with fatigue in a dose-response manner(p=0.001),and higher body weight was independently associated with poor sleep quality in an inverted U pattern(p=0.021).Conclusion:Relative VO_(2peak)appears to be a critical HRF component associated with multiple patient-reported symptoms in newly diag

关键词： Breast cancer Fatigue Depression Sleep quality Cardiorespiratory fitness

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Continuity of care by a primary midwife(caseload midwifery):a cost analysis using results from the COSMOS randomised controlled trial

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Gynecology and Obstetrics Clinical Medicine 2024年第2期4卷 94-101页

作者： Emily j Callander Hannah jackson Helen l Mclachlan Mary-Ann Davey Della A Forster University of Technology Sydney SydneyNew South WalesAustralia The Royal Women's Hospital MelbourneVictoriaAustralia Faculty of Health University of Technology SydneyBroadwayNew South WalesAustralia judith lumley Centre La Trobe UniversityMelbourneVictoriaAustralia School of Nursing and Midwifery a Trobe UniversityMelbourneVictoriaAustralia Department of Obstetrics and Gynaecology Monash UniversityClaytonVictoriaAustralia

Introduction Caseload midwifery(continuity of midwifery carer)offers benefits including lower caesarean section rates,lower risks of preterm birth and stilbirth,and improved maternal satisfaction of *** these advantages,concerns about additional costs hinder widespread *** study examinesthecost of caseload midwifery compared with standard maternity care from the perspective of both public hospitals and public *** A cost analysis was conducted using data from a randomised controlled trial of 2314 low-risk pregnant women in Melbourne,*** randomised to caseload care received antenatal,intrapartum and postpartum care from a primary midwife,with some care provided by a‘back-up'*** in standard care received midwifery-led care with varying levels of continuity,junior obstetric care or community-based medical *** cost analysis compared differences in mean costs of health resources to public hospitals and to public ***,a budget impact analysis estimated total costs to the health system between 2023 and *** For public hospitals,there was no significant difference in overall costs between women receiving caseload midwifery(n=1146)versus standard care(n=1151)($SA12363(SD:$A4967)vs$A12323(SD:$A7404);p=0.85).Conversely,public funders incurred lower expenditures for women receiving caseload midwifery($A20330(SD:$A8312))versus standard care($A21637(SD:$A11818);plysis estimated savings of sA625million to the health system over the next 5 years with expanded access to caseloadmidwifery *** Caseloadmidwifery in low-risk women is cost-neutral to public hospitals and cost-saving to public *** abstract Continuity of midwifery for low-risk women reduces costs to public funders,with no additional costs to hospitals.

关键词： random continuity Continuity

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Evolution of microstructure and properties of a novel Ni-based superalloy during stress relief annealing

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International.j.urnal of Minerals,Metallurgy and Materials 2024年第8期31卷 1876-1889页

作者： lei jia Heng Cui Shufeng Yang Shaomin lü Xingfei Xie jinglong Qu Collaborative Innovation Center of Steel Technology University of Science and Technology BeijingBeijing 100083China State Key laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China Beijing GAONA Materials&Technology Co. Ltd.Beijing 100081China High-Temperature Materials Institute Central Iron and Steel Research InstituteBeijing 100081China

We discussed the decrease in residual stress,precipitation evolution,and mechanical properties of GH4151 alloy in different annealing temperatures,which were studied by the scanning electron microscope(SEM),high-resolution transmission electron microscopy(HRTEM),and electron backscatter diffraction(EBSD).The findings reveal that annealing processing has a significant impact on diminishing residual *** the annealing temperature rose from 950 to 1150℃,the majority of the residual stresses were relieved from 60.1 MPa down to 10.9 ***,the stress relaxation mechanism transitioned from being mainly controlled by dislocation slip to a combination of dislocation slip and grain boundary ***,the annealing treatment promotes the decomposition of the laves,accompanied by the precipitation ofμ-(Mo_(6)Co_(7))starting at 950℃ and reaching a maximum value at 1050℃.The tensile strength and plasticity of the annealing alloy at 1150℃ reached the maximum(1394 MPa,56.1%)which was 131%,200%fold than those of the as-cast alloy(1060 MPa,26.6%),but the oxidation process in the alloy was accelerated at 1150℃.The enhancement in durability and flexibility is primarily due to the dissolution of the brittle phase,along with the shape and dispersal of theγ′phase.

关键词： GH4151 alloy annealing treatment residual stress precipitation evolution strength mechanical properties

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Effects of welding parameters and post-heat treatment on mechanical properties of friction stir welded AA2195-T8 Al-li alloy

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journal of Materials Science & Technology 2018年第1期34卷 219-227页

作者： j. Zhang X.S. Feng j.S. Gao H. Huang Z.Q. Ma l.j. Guo Technical Center Shanghai Aerospace Equipments Manufacturer Shanghai 200245. China

In this study, the effects of main welding parameters （rotation speed （ω） and welding speed （υ）） on the microstructure, micro-hardness distribution and tensile properties of friction stir welded （FSW） 2195-T8 Al-li alloy were investigated. The effects of T6 post-treatments at different solution and aging conditions on the mechanical properties and microstructure characteristics of the FSW joints were also investigated. The results show that with increasing to and v, both strength and elongation of the joints increase first, and then decrease with further increase of ω and υ. All the joints under varied welding parameters show significant strength loss, and the strength reaches only 65% of the base metal, The effect of T6 post-heat treatment on the mechanical properties of the joints depends on the solution and aging conditions. Two heat treatment processes （480 ℃×0.5 h quenching＋ 180 ℃× 12 h, 520 ℃× 0.5 h quenching＋ 180 ℃×12h aging） are found to increase the joint strength. Furthermore, low temperature quenching （480℃） is more beneficial to the joint strength. The joint strength can reach 85% of the base metal. Whereas both low temperature aging （140 ℃× 56h） and stepped aging （ 100 ℃× 12 h ＋ 180 ℃× 3 h） processes decrease the joint strength. After heat treatment all the joints show decreased ductility due to the obvious grain coarsening in the nugget zone （NZ） and thermo-mechanically affected zone （TMAZ）.

关键词： 2195-T8 Al-li alloy Friction stir welding Welding parameters Post-heat treatment

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PRECIPITATION BEHAVIOR OF M_(2)N IN A HIGH-NITROGEN AUSTENITIC STAINlESS STEEl DURING ISOTHERMAl AGING

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Acta Metallurgica Sinica(English letters) 2007年第2期20卷 95-101页

作者： F. Shi l.j. Wang W.F. Cui C.M. liu School of Materials ＆ Metallurgy Northeastern UniversityShenyang 110004 China

The precipitation behavior of M2N and the microstructural evolution in a Cr-Mn austenitic stainless steel with a high nitrogen content of 0.43mass% during isothermal aging has been investigated using optical microscopy （ OM）, scanning electron microscopy （SEM）, and transmission electron microscopy （TEM）. The aging treatments have led to the decomposition of nitrogen supersaturated austenitic matrix through discontinuous cellular precipitation. The precipitated cells comprise alternate lamellae of M2N precipitate and austenitic matrix. This kind of precipitate morphology is similar to that of pearlite. However, owing to the non-eutectoidic mechanism of the reaction, the growth characteristic of the cellular precipitates is different from that of pearlite in Fe-C binary alloys. M2N precipitate in the cell possesses a hexagonal crystal structure with the parameters a = 0.4752nm and c = 0.4429nm, and the orientation relationship between the M2V precipitates and austenite determined from the SADP is [01^-10]M2N//[101]γ, [2^-1^-10]M2N//[010]γ.

关键词： austenitic stainless steel high nitrogen microstructureisothermal aging precipitation

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Surface engineering with ionic polymers on membranes for boron removal

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Frontiers of Chemical Science and Engineering 2024年第5期18卷 61-69页

作者： Xiting Zhang Chenyi Fang j Paul Chen Sui Zhang Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117576Singapore Department of Civil and Environmental Engineering National University of SingaporeSingapore 119260Singapore College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060China

Removal of boric acid from seawater and wastewater using reverse osmosis membrane technologies is imperative and yet remains inadequately addressed by current commercial *** research efforts performed post-modification of reverse osmosis membranes to enhance boron rejection,which is usually accompanied by substantial sacrifice in water *** study delves into the surface engineering of low-pressure reverse osmosis membranes,aiming to elevate boron removal efficiency while maintaining optimal salt rejection and water *** were modified by the self-polymerization and co-deposition of dopamine and polystyrene sulfonate at varying ratios and *** surfaces became smoother and more hydrophilic after *** optimum membrane exhibited a water permeability of 9.2±0.1 l·m^(-2)·h^(-1)·bar^(-1),NaCl rejection of 95.8%±0.3%,and boron rejection of 49.7%±0.1% and 99.6%±0.3% at neutral and alkaline pH,*** water permeability is reduced by less than 15%,while the boron rejection is 3.7 times higher compared to the blank *** research provides a promising avenue for enhancing boron removal in reverse osmosis membranes and addressing water quality concerns in the desalination process.

关键词： membrane low-pressure reverse osmosis boron surface engineering

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Quantitative Applications of Weather Satellite Data for Nowcasting:Progress and Challenges

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journal of Meteorological Research 2024年第3期38卷 399-413页

作者： jun lI jing ZHENG Bo lI Min MIN Yanan lIU Chian-Yi lIU Zhenglong lI WPaul MENZEl Timothy j.SCHMIT john l.CINTINEO Scott lINDSTROM Scott BACHMEIER Yunheng XUE Yayu MA Di DI Han lIN Innovation Centre for Fengyun Meteorological Satellite(FYSIC) National Satellite Meteorological CentreChina Meteorological AdministrationBeijing100081China School of Atmospheric Sciences and Guangdong Province Key laboratory for Climate Change and Natural Disaster Studies Sun Yat-sen University and Southern Laboratory of Ocean Science and EngineeringZhuhai519082China Key laboratory of Geographic Information Science(Ministry of Education) East China Normal UniversityShanghai200241China Research Center for Environmental Changes Academia SinicaTaipei11529China Cooperative Institute for Meteorological Satellite Studies University of Wisconsin-MadisonMadisonWI53706USA Sensors and Calibration Branch STAR/NESDISMadisonWI53706USA Wuxi University Wuxi214105China School of Computer Science Chengdu University of Information TechnologyChengdu610225China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing210044China Key laboratory of Spatial Data Mining and Information Sharing of Ministry of Education National and Local Joint Engineering Research Center of Satellite Geospatial Information TechnologyFuzhou UniversityFuzhou350108China

Monitoring and predicting highly localized weather events over a very short-term period,typically ranging from minutes to a few hours,are very important for decision makers and public *** these events usually relies on radar observations through monitoring and *** advanced high-resolution imaging and sounding observations from weather satellites,nowcasting can be enhanced by combining radar,satellite,and other data,while quantitative applications of those data for nowcasting are advanced through using machine learning *** applications include monitoring the location,impact area,intensity,water vapor,atmospheric instability,precipitation,physical properties,and optical properties of the severe storm at different stages(pre-convection,initiation,development,and decaying),identification of storm types(wind,snow,hail,etc.),and predicting the occurrence and evolution of the *** observations can provide information on the environmental characteristics in the preconvection stage and are very useful for situational awareness and storm *** paper provides an overview of recent progress on quantitative applications of satellite data in nowcasting and its challenges,and future perspectives are also addressed and discussed.

关键词： weather satellite quantitative applications nowcasting pre-convection

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On B(5,20) 2-Groups

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AlGEBRA COllOQUIUM 2024年第3期31卷 429-440页

作者： Alhassan, E. A. Tan, Y. l. li, Y. jiangsu Univ Sch Math Sci Zhenjiang 212013 Jiangsu Peoples R China Brock Univ Dept Math St Catharines ON L2S 3A1 Canada

A finite group G is said to be a B( n, k) group if for any n-element subset { a(1) , & mldr; , a(n) } of G, | { a(i) a(j )| 1 <= i, j <= n } | <= k . It is of interest to characterize the structure of B( n, k) groups ... 详细信息

A finite group G is said to be a B( n, k) group if for any n-element subset { a(1) , & mldr; , a(n) } of G, | { a(i) a(j )| 1 j l authors. In this paper, we give a complete characterization of B( 5, 20) 2-groups by showing there are five classes of such groups which are nontrivial and nonabelian.

关键词： B(n, k) groups small squaring property central extension GAP

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Solid-state NMR studies of proteins in condensed phases

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Magnetic Resonance letters 2024年第3期4卷 1-10页

作者： jiani Xiang Xialian Wu Angelo l.Chu junxia lu Key laboratory of Industrial Fermentation(Ministry of Education) School of Life and Health SciencesHubei University of TechnologyWuhan430068China Interdisciplinary Institute of NMR and Molecular Sciences School of Chemistry and Chemical EngineeringThe State Key Laboratory of Refractories and MetallurgyWuhan University of Science and TechnologyWuhan430081China Thomas jefferson High School for Science and Technology 6560 Braddock RdAlexandriaVA22312USA

Some proteins perform their biological functions by changing their material states through liquid-liquid phase *** phase separation,the protein condenses into a concentrated liquid phase and sometimes into a gel phase,changing its dynamic properties and intermolecular interactions,thereby regulating cellular *** the biological significance of this phenomenon has been widely recognized by researchers,there is still a lack of a comprehensive understanding of the structural and dynamic properties of the protein in the condensed *** this phase,molecules usually contain domains with varied dynamic properties and undergo intermediate *** angle spinning(MAS)solid-state NMR(SSNMR)experiments are very powerful in studying rigid protein polymers such as *** incorporation of solution-like experiments into SSNMR and the development of j-coupling based MAS SSNMR techniques extend its ability to study partially mobile segments of proteins in a condensed liquid or gel phase which are not visible by solution NMR or dipolar-coupling based ***,it has been applied in studying protein condensation and has provided very important information that is hard to obtain by other techniques.

关键词： Magic angle spinning(MAS)solid-state NMR(SSNMR) Protein condenses j-coupling based MAS SSNMR liquid-liquid phase separation

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Improved Analytical Methods for Determination of Residues of Nitrapyrin and 6-Chloropicolinic Acid in Different Crop Matrices by liquid Chromatography-Tandem Mass Spectrometry

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journal of Agricultural Chemistry and Environment 2024年第3期13卷 263-281页

作者： Fabiola G. Zuno-Floriano Riza l. Reyes-Punongbayan Matt j. Hengel Department of Environmental Toxicology University of California Davis California USA

Novel analytical methods were developed for the determination of nitrapyrin and 6-chloropicolinic acid (6-CPA) residues in agricultural products. Nitrapyrin was extracted with hexane: toluene (1:1, v/v) and 6-CPA with 0.1 N sodium hydroxide (NaOH). For nitrapyrin, samples were cleaned with silica solid phase extraction (SPE) and for 6-CPA with C18 or carbon SPE. Analysis was performed by liquid chromatography-tandem mass spectroscopy (lC-MS/MS) with external calibration (0.010 to 0.0010 µg∙ml−1 for nitrapyrin and 0.0050 to 0.00025 µg∙ml−1 for 6-CPA). Recoveries for nitrapyrin and 6-CPA were 68% - 102% and 66% - 90%, respectively. Nitrapyrin was detected in celery and onion (−1) and 6-CPA in onion, mustard greens and lettuce (−1). lower level method validation (llMV) for nitrapyrin and 6-CPA was 0.020 µg∙g−1 and 0.050 µg∙g−1, respectively. The methods presented in this study are robust and were utilized for the registration of nitrapyrin on agricultural commodities in the United States.

关键词： Herbicide Agricultural Products External Calibration lC-MS/MS Registration

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