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On the uncertainty of interwell connectivity estimations from the capacitance-resistance model

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Petroleum Science 2014年第2期11卷 265-271页

作者： Gustavo A Moreno larry w Lake YPF Macacha Güemes 515 YPF-Tecnología Baradero S/N (1925) Center for Petroleum and Geosystems Engineering University of Texas at Austin

The capacitance-resistance model （CRM） is an alternative to conventional reservoir simulation. CRM, a simplification of complex numerical models, uses production and injection rates to infer a reservoir description. There is no prior geologic model. The principal output of CRM fitting is the fraction of injected fluid （usually water） that is produced at a producer at steady-state. These fractions are interwell connectivities. Interwell connectivities are fundamental information needed to manage waterfloods in oil reservoirs. The data-driven CRM is a fast tool to estimate these parameters in mature fields and allows one to make full use of the dynamic data available. This paper considers the problem of setting an upper bound on the uncertainty of interwell connectivities for linear-constrained models. Using analytical bounds and numerical simulations, we derive a consistent upper limit on the uncertainty of interwell connections that can be used to quantify the information content of a given dataset.

关键词： Data-driven models capacitance-resistance model secondary recovery waterfloodoptimization interwell connectivities

Input signal design to estimate interwell connectivities in mature fields from the capacitance-resistance model

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Petroleum Science 2014年第4期11卷 563-568页

作者： Gustavo A.Moreno larry w.Lake YPF-Tecnología Baradero S/N (1925) EnsenadaBuenos AiresArgentina YPF Macacha Guemes 515CABAArgentina CPARM University of Texas at AustinAustinTXUSA

Interwell connectivities are fundamental parameters required to manage waterfloods in oil reservoirs. Data-driven models, such as the capacitance-resistance model （CRM）, are fast tools to estimate these parameters from time-correlations of input （injection rates） and output （production rates） signals. Noise and structure of the input time-series impose limits on the information that can be extracted from a given data-set. This work uses the CRM to study general prescriptions for the design of input signals that enhance the information content of injection/production data in the estimation of well-to-well interactions. Numerical schemes and general features of the optimal input signal strategy are derived for this problem.

关键词： Intervell connectivity capacitance-resistance model mature field experiment design

Control of the hydrophobicity of rare earth oxide coatings deposited by solution precursor plasma spray by hydrocarbon adsorption

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Journal of Materials Science & Technology 2021年第3期62卷 107-118页

作者： Pengyun xu Guohui Meng larry Pershin Javad Mostaghimi Thomas w.Coyle Centre for Advanced Coating Technologies University of TorontoTorontoON M5S 3G8Canada

The basis of the hydrophobicity of lanthanide rare earth oxides(REOs)has been the subject of considerable *** explore this question,the wetting behaviors and surface compositions of hierarchicallystructured Yb_(2)o_(3)(one of the REOs)coatings and non-REO Al_(2)o_(3)coatings deposited via solution precursor plasma spray process were investigated in this *** Yb_(2)o_(3)coatings were subjected to a number of post-deposition treatments including vacuum(1-15 Pa)treatment,Ar-plasma treatment,heat treatment(400℃),long-time air exposure and ultra-high vacuum(1×10^(-7)Pa)*** characterization showed that different post-deposition treatments resulted in different wetting behavior for the Yb_(2)o_(3)coatings which correlated with the content of hydrocarbon on the ***_(2)o_(3)coatings exhibited reversible transitions between superhydrophobicity after vacuum treatment and superhydrophilicity after Ar-plasma or heat treatment,linked to hydrocarbon adsorption onto and desorption from the ***_(2)o_(3)coatings after long-time air exposure and ultra-high vacuum treatment both remained hydrophilic and showed a smaller hydrocarbon content than coatings after vacuum ***_(2)o_(3)coatings with hierarchical surface structures similar to the Yb_(2)o_(3)coatings showed an increase in wCA to only-170 after the same vacuum treatment,indicating the REO has a much higher affinity for hydrocarbon adsorption than Al_(2)o_(3),and that the content of hydrocarbon adsorbed on the surface of the REO determined the wetting behavior.

关键词： Rare earth oxide Hydrophobicity Solution precursor plasma spray Post-deposition treatments

DIETARY wATER AND SODIUM REQUIREMENTS FOR ACTIVE ADULTS

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中国运动医学杂志 2005年第6期24卷 751-756页

作者： w. larry Kenney Physiology and Kinesiology Pennsylvania State University University Park PA Ph.D. FACSM

KEY POINTSAbstract: The 2004 recommendations on water and sodium intake from the Institute of Medicine (IOM) of the National Academy of Sciences are targeted primarily at sedentary Americans. These guidelines for water and salt intake should not be applied to athletes.  Athletes who follow the IOM recommendations to the letter may actually put themselves at risk for unintended decreases in performance or even untoward health consequences.

关键词：运动医学饮水卫生钠元素微量元素

Irrigation ponds:Possibility and potentials for the treatment of drainage water from paddy fields in Zhanghe Irrigation System

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Science China(Technological Sciences) 2009年第11期52卷 3320-3327页

作者： BROwN larry Ohio State University 590 Woody Hayes Drive Columbus OH 43210-1057 USA

Excessive application of fertilizers and pesticides as well as discharge of undecontaminated and unrecycled waste of livestock and poultry into farmland has caused serious non-point source pollution (NSP) of farmland in China. with the traditional mode of irrigation and drainage in rice-based irrigation systems, the pollution of farmland drainage water has become more and more serious. Traditional irrigation and drainage systems only focus on issues concerning water quantity, i.e. the capacity of irrigation in drought and drainage in waterlogging period, yet have no requirement on water quality improvement. how to clean the water quality of farmland drainage through remodeling the existing irrigation and drainage systems has a very important realistic meaning. Pond is an important irrigation facility in rice-based irrigation systems in southern China, which has the functions of not only a storage of water from canals but also collections of surface runoffs and farmland drainage for recycling use. Such water storage features of pond provide the possibility and potential capacity for drainage water treatment by managing such features as treatment basins as the growth of aquatic plants as well as living of fishes, batrachia and microorganisms in pond forms a soil-plant-microorganism ecological system. To explore the potential capacity of pond for drainage water nutrient reduction, the Zhanghe Irrigation System of Hubei, a typical "melon-on-the-vine" system in southern China is selected as the research site. The results of pond survey and field experiments demonstrate that plenty of ponds are suitable for collecting and cleaning paddy field drainage, and the ponds are favorable in reducing N, P nutrients in the drainage water. Other issues, e.g. how to maximize such capacity and what strategies should be sought to make existing treatment basins hydraulically more efficient, are also discussed.

关键词： agricultural non-point source pollution irrigation and drainage system treatment basin pond management water quality

An infertile male with dilated seminal vesicles due to functional obstruction

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Asian Journal of Andrology 2017年第2期19卷 256-257页

作者： Michael D Font Alexander w Pastuszak John R Case larry I Lipshult Baylor College of Medicine Houston TX 77030 USA Center for Reproductive Medicine Baylor College of Medicine Houston TX 77030 USA Scott Department of Urology Baylor College of Medicine Houston TX 77030 USA Urology San Antonio San Antonio TX 78229 USA

Dear Editor, The patient is a 45-year-old male who presented to an outside clinic in 2014 for evaluation of painful ejaculation, infertility, and difficulty with urination for as long as he could remember. He reported no past significant medical or surgical history and no family history of infertility. He was given a trial of tamsulosin without improvement in his symptoms. Initial semen analysis demonstrated azoospermia.

关键词： infertile male dilated seminal vesicles due functional obstruction

A clickable photoaffinity probe of betulinic acid identifies tropomyosin as a target

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Acta Pharmaceutica Sinica B 2022年第5期12卷 2406-2416页

作者： Pedro Martín-Acosta Qianli Meng John Klimek Ashok P.Reddy larry David Stefanie Kaech Petrie Bingbing x.Li xiangshu xiao Program in Chemical Biology Department of Chemical Physiology and BiochemistryOregon Health&Science UniversityPortlandOR 97239USA Proteomics Shared Resource Oregon Health&Science UniversityPortlandOR 97239USA Knight Cancer Institute Oregon Health&Science UniversityPortlandOR 97239USA Department of Neurology Oregon Health&Science UniversityPortlandOR 97239USA

Target identification of bioactive compounds is important for understanding their mechanisms of action and provides critical insights into their therapeutic utility. while it remains a challenge,unbiased chemoproteomics strategy using clickable photoaffinity probes is a useful and validated approach for target identification. One major limitation of this approach is the efficient synthesis of appropriately substituted clickable photoaffinity probes. Herein, we describe an efficient and consistent method to prepare such probes. we further employed this method to prepare a highly stereo-congested probe based on naturally occurring triterpenoid betulinic acid. with this photoaffinity probe, we identified tropomyosin as a novel target for betulinic acid that can account for the unique biological phenotype on cellular cytoskeleton induced by betulinic acid.

关键词： Betulinic acid Cancer Diazirine Natural product Photoaffinity probe Tropomyosin

Advanced regeneration and fixed-bed study of ammonium and potassium removal from anaerobic digested wastewater by natural zeolite

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Journal of Environmental Sciences 2013年第5期25卷 954-961页

作者： xuejun Guo larry Zeng xin Jin State Key Laboratory of water Environment Simulation School of EnvironmentBeijing Normal University Environmental Technologies Alberta Research Council Inc.VegrevilleAlberta T9C 1T4Canada

Highly efficient regeneration of natural zeolite was developed in conjunction with the removal of high concentrations of ammonia and potassium from the reverse osmosis effluent of anaerobic-digested wastewater by fixed-bed ion *** elution and uptake behavior of ammonium and potassium in the fixed bed were *** batch desorption tests and on-column regeneration were conducted to develop an optimum regeneration condition compatible with the wastewater *** effectiveness of ammonium elution increased with increasing alkaline *** increase of salt dose significantly enhanced the ammonium maximum in the elution *** ammonium elution was achieved in 6 bed volumes（BV） when the alkaline and salt concentrations were respectively 0.1 mol/L and 18.6 g/L at a flow rate of 2.5-3.0 BV/*** to the higher affinity of potassium with natural clinoptilolite,complete potassium elution was not achieved in all cases.

关键词： regeneration removal ammonium potassium natural zeolite

International Union for Biological Sciences Symposium on Integrative Biology of Reproductive and Social Behaviors

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Integrative Zoology 2007年第1期2卷 36-55页

作者： larry J YOUNG 不详

SRA regulates female meiosis,ovulation and reproductive behavior in Drosophila Toshiro AIGAKI Department of Biology,Tokyo Metropolitan University,Minamiosawa,Tokyo,Japan(aigaki-toshiro@***)Mating induces dramatic changes in the reproductive behavior of females in Drosophila *** better understand the genetic bases of post-mating responses in females,we screened a collection of P{GS}insertion lines,and identified sarah(sra),whose misexpression in the nervous system induced high levels of ovulation in *** flies also extruded the ovipositor toward courting males as seen in wild-type mated females,supporting the notion that ovulation and behavioral patterns are physiologically *** sra insertions were found to be hypomorphic alleles with reduced expression levels.

关键词： insertion bases behavior