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中国家禽 2003年第16期 33-34页

作者： Kevin A.Janni ,larry d.jacobson

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禽舍的自然通风

中国家禽 2003年第16期25卷 30-31页

作者： Kevin A.Janni larry d.jacobson

Temperature variable and the efficiency of sperm mediated transfection of HPV16 dNA into cells

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Asian Journal of Andrology 2002年第3期4卷 169-173页

作者： Ruslana Kadze Philip J.Chan John d.jacobson Johannah U.Corselli Alan King Center for Fertility and In Vitro Fertilization Department of Gynecology and Obstetricsand Department of Physiology and PharmacologyLoma Linda University School of MedicineLoma LindaCalifornia 92350USA

Aim:To pretreat sperm at various temperatures before exposure to human papillomavirus(HPV)16 dNA fragments and to assess the efficiency of HPV carrier sperm to transfect cumulus ***:Cumulus cells from follicular aspirates were obtained,pooled and divided into culture dishes containing Sybr Gold-stained HPV dNA carrying sperm that were either pretreated at 4℃,37℃or 40℃(n=5).The cells were incubated in 5%CO_(2) in air mixture at 37℃for 24 *** efficiency of sperm to take up fluorescent HPV dNA was determined at hour *** incubation,cumulus cell viability was assessed using the e0sin method and the percentages of fluorescent cumulus cells ***:Over half of all the cumulus cells became fluorescent with the highest percentage in the 37℃*** pretreated at 4℃had the greatest amount of HPV dNA *** sperm motility was similar for the 3 pretreatment *** were no differences in cumulus viability among the ***:Sperm pretreated at 37℃transferred the greatest amount of fluorescent HPV dNA fragments to the cumulus *** HPV dNA was observed in the nuclear and cytoplasmic *** data suggested the possibility of sperm as a vector for the transmission of HPV dNA to the cumulus cells surrounding ovulated oocytes,which might lead to early implantation failures.

关键词： spermatozoa human papillomavirus gene transfer cumulus fertility

Recovery rates of persistent post-COVId-19 olfactory dysfunction using psychophysical assessment:A longitudinal cohort study

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 79-87页

作者： Jeremy P.Tervo Patricia T.jacobson Brandon J.Vilarello Tiana M.Saak Francesco F.Caruana Liam W.Gallagher Joseph B.Gary david A.Gudis Paule V.Joseph d.P.devanand Terry E.Goldberg Jonathan B.Overdevest Columbia University Vagelos College of Physicians and Surgeons New YorkNew YorkUSA department of Otolaryngology-Head and Neck Surgery New York-Presbyterian/Columbia University Irving Medical CenterNew YorkNew YorkUSA department of Otolaryngology-Head and Neck Surgery University of PittsburghPittsburghPennsylvaniaUSA department of Otolaryngology-Head and Neck Surgery University of MinnesotaMinneapolisMinnesotaUSA National Institute of Alcohol Abuse and Alcoholism Section of Sensory Science and Metabolism&National Institute of Nursing ResearchBethesdaMarylandUSA New York-Presbyterian/Columbia University Irving Medical Center New YorkNew YorkUSA

Objectives:Persistent olfactory dysfunction(Od)following loss of smell associated with SARS-CoV-2 infection is a major feature of long *** on the prevalence of persistent Od predominantly rely on self-reported olfactory *** studies have tracked longitudinal rates of recovery using psychophysical assessment among patients presenting for evaluation of persistent Od beyond a window of acute *** anchored in standardized testing methods are needed to counsel patients who fail to acutely regain their sense of *** study aims to quantify the degree of persistent Od in post-COVId-19 patients who experience subjective and psychophysical ***:We grouped participants presenting for Od evaluation into cohorts based on both subjective and psychophysical olfactory status at a baseline assessment and assessed their olfactory abilities with a visual analogue scale and the Sniffin'Sticks extended test at baseline and 1-year time *** had confirmed a history of COVId-19 by lab evaluation or clinical diagnosis if lab evaluation was not ***:Baseline olfactory evaluation was completed by 122 participants,53 of whom completed the 1-year follow-up *** participants presenting with perceived Od,74.5%had confirmed psychophysical Od at baseline,with 55.1%at 1-year *** had reliable trends in self-rated versus psychophysically tested olfactory function at both time *** total threshold,discrimination,and identification(TdI)score improved by+3.25 points in the cohort with psychophysical Od(p=0.0005),with this improvement largely attributable to an increase in median threshold scores(+2.75 points;p=0.0004).Conclusions:Od persists in a significant number of patients who fail to acutely recovery their sense of smell after COVId-19,with many demonstrating lingering deficits at *** in threshold,but not discrimination or identification,most significantly mediate improvement

关键词： long COVId olfaction post-COVId condition smell dysfunction

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欧区东扩：新的风险

欧洲一体化研究 2002年第2期 33-38页

作者： MichaelBolle&H-d.jacobson 周韬

IPR, Trade, FdI, and Technology Transfer

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Frontiers of Economics in China-Selected Publications from Chinese Universities 2014年第4期9卷 529-555页

作者： Tan Li larry d. Qiu Faculty of Business and Economics The University of Hong Kong Hong Kong China

In this survey, we discuss how intellectual property rights （IPR） protection in the South affects trade flows, foreign direct investment （FdI） flows, and technology transfers from the North to the South. We also discuss optimal IPR policies and their effect on innovation. Our discussion covers both theoretical studies and empirical evidence. This survey is both comprehensive and critical. It aims to give readers the current state of IPR and globalization literature. Some issues have been studied more thoroughly, whereas for others the surface has only been scratched upon. This survey gives readers a clearer picture of the literature and may help them find future research topics.

关键词： IPR trade FdI technology transfer

Cross-Country Externalities of Trade and FdI Liberalization

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Frontiers of Economics in China-Selected Publications from Chinese Universities 2013年第1期8卷 19-49页

作者： Qing Liu larry d. Qiu School of International Trade and Economics University of International Business and Eco-nomics Beijing 100029 China School of Economics and Finance The University of Hong Kong Hong Kong China

We develop a three-country heterogeneous-firm model and show that FdI liberalization in one foreign country （F1） results in the following：（i） some firms from the home country switch from export to FdI in F1; （ii） skilled labor＇s wage rate drops in the home country; （iii） wage inequality between the skilled and unskilled labor decreases; and （iv） some firms from the home country switch from FdI to export to another foreign country （F2）. The effects from trade liberalization are just the opposite, but the effects from education improvement are qualitatively the same as FdI liberalization. The cross-country externalities work through the domestic labor market.

关键词： export FdI finn heterogeneity cross-country externalities wage in-equality skill training contractual friction

Few-Shot Learning Enables Population-Scale Analysis of Leaf Traits in Populus trichocarpa

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Plant Phenomics 2023年第3期5卷 581-597页

作者： John Lagergren Mirko Pavicic Hari B.Chhetri larry M.York doug Hyatt david Kainer Erica M.Rutter Kevin Flores Jack Bailey-Bale Marie Klein Gail Taylor daniel jacobson Jared Streich Biosciences division Oak Ridge National LaboratoryOak RidgeTNUSA department of Applied Mathematics University of CaliforniaMercedCAUSA department of Mathematics North Carolina State UniversityRaleighNCUSA department of Plant Sciences University of CaliforniaDavisCAUSA

Plant phenotyping is typically a time-consuming and expensive endeavor,requiring large groups of researchers to meticulously measure biologically relevant plant traits,and is the main bottleneck in understanding plant adaptation and the genetic architecture underlying complex traits at population *** this work,we address these challenges by leveraging few-shot learning with convolutional neural networks to segment the leaf body and visible venation of 2,906 Populus trichocarpa leaf images obtained in the *** contrast to previous methods,our approach(a)does not require experimental or image preprocessing,(b)uses the raw RGB images at full resolution,and(c)requires very few samples for training(e.g.,just 8 images for vein segmentation).Traits relating to leaf morphology and vein topology are extracted from the resulting segmentations using traditional open-source image-processing tools,validated using real-world physical measurements,and used to conduct a genome-wide association study to identify genes controlling the *** this way,the current work is designed to provide the plant phenotyping community with(a)methods for fast and accurate image-based feature extraction that require minimal training data and(b)a new population-scale dataset,including 68 different leaf phenotypes,for domain scientists and machine learning *** of the few-shot learning code,data,and results are made publicly available.

关键词： networks neural image

An analysis of the China–US trade war through the lens of the trade literature

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Economic and Political Studies 2019年第2期7卷 148-168页

作者： larry d.Qiu Chaoqun Zhan Xing Wei Faculty of Business and Economics The University of Hong KongHong Kong SARChina Lingnan College Sun Yat-sen UniversityGuangzhouChina

The current China–US trade war that started in early 2018 has been the largest of this kind in the global market in the past half century,if not *** speculations about the reasons for and progress and potential implications of the trade war *** must understand the reasons for the war to avoid future trade *** what will happen in the near future and the related economic consequences are even more important for people(including businessmen and government policymakers)to prepare for them and make corresponding ***,endeavouring to predict is a tough *** paper tries to provide an unbiased analysis through the lens of the trade *** is,we want to ask how much we can understand the current trade war on the basis of the accumulated knowledge we can obtain from our *** theories include imperfect competition,increasing returns,terms of trade argument,distributional effects and political economy argument.

关键词： Trade war China-US trade trade theories tradepolicy

An infertile male with dilated seminal vesicles due to functional obstruction

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Asian Journal of Andrology 2017年第2期19卷 256-257页

作者： Michael d Font Alexander W Pastuszak John R Case larry I Lipshult Baylor College of Medicine Houston TX 77030 USA Center for Reproductive Medicine Baylor College of Medicine Houston TX 77030 USA Scott department of Urology Baylor College of Medicine Houston TX 77030 USA Urology San Antonio San Antonio TX 78229 USA

dear Editor, The patient is a 45-year-old male who presented to an outside clinic in 2014 for evaluation of painful ejaculation, infertility, and difficulty with urination for as long as he could remember. He reported no past significant medical or surgical history and no family history of infertility. He was given a trial of tamsulosin without improvement in his symptoms. Initial semen analysis demonstrated azoospermia.

关键词： infertile male dilated seminal vesicles due functional obstruction