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Effect of continuous annealing temperature on microstructure and properties of ferritic rolled interstitial-free steel

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International Journal of Minerals,Metallurgy and Materials 2018年第5期25卷 536-546页

作者： Chen-yang Qiu lang li Lei-lei Hao Jian-gong Wang Xun Zhou Yong-lin Kang School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Shougang Jingtang United Iron and Steel Co.Ltd. Tangshan 063200China 不详

In this report,the microstructure,mechanical properties,and textures of warm rolled interstitial-free steel annealed at four different temperatures(730,760,790,and 820°C)were *** overall structural features of specimens were investigated by optical microscopy,and the textures were measured by X-ray diffraction(XRD).Nano-sized precipitates were then observed by a transmission electron microscope(TEM)on carbon extraction *** to the results,with increased annealing temperatures,the ferrite grains grew;in addition,the sizes of Ti_4C_2S_2 and Ti C precipitates also ***,the sizes of Ti N and Ti S precipitates slightly *** the annealing temperature increased from 730 to 820°C,the yield strength(YS)and the ultimate tensile strength(UTS)showed a decreasing ***,elongation and the strain harden exponent(n value)increased to 49.6%and 0.34,*** comparing textures annealed at different temperatures,the intensity of{111}texture annealed at 820°C was the largest,while the difference between the intensity of{111}and{111}was the smallest when the annealing temperature was 820°***,the plastic strain ratio(r value)annealed at 820°C was the highest.

关键词： interstitial-free steel warm rolling texture mechanical properties microstructure

Efficiency and safety of laparoscopic left hemihepatectomy: A study of intrathecal vs extrathecal Glissonean pedicle techniques

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2612-2619页

作者： li-Min Kang Lei Xu Fu-Wei Zhang Fa-Kun Yu li lang Department of Hepatobiliary and Pancreatic Surgery Puer People's HospitalPuer 665000Yunnan ProvinceChina Department of Outpatient Puer People's HospitalPuer 665000Yunnan ProvinceChina

BACKGROUND Selective hemihepatic vascular occlusion is utilized in both right and left hemihepatectomies to preserve blood supply to the intact lobe,maintain hemo-dynamic stability,and mitigate surgical *** this technique encompasses both intrathecal and extrathecal Glissonean pedicle transection methods,there is a lack of systematic comparative reports on these two *** To retrospectively analyze the clinical data of patients with hepatocellular carcinoma(HCC)undergoing laparoscopic anatomical hepatectomy in our hospital to explore the feasibility,safety,and short-and long-term efficacy of extrathecal and intrathecal Glissonean pedicle transection methods in laparo-scopic left *** A retrospective study was performed to analyze the clinical data of 49 HCC patients who underwent laparoscopic left hemihepatectomy from January 2019 to December 2022 in our *** patients were divided into extrathecal Glissonean pedicle transection(EGP)group(n=24)and intrathecal Glissonean pedicle transection(IGP)group(n=25)according to the different approaches used for selective hemihepatic vascular *** perioperative indicators,liver function indexes,complications,and follow-up findings were compared between these two *** The surgeries were smooth in both groups,and no perioperative death was *** hepatic pedicle transection time and the operation time were(16.1±2.3)minutes and(129.6±19.0)minutes,respectively,in the EGP group,which were significantly shorter than those in the IGP group[(25.5±2.4)minutes and(184.8±26.0)minutes,respectively],both Pling time,and postoperative liver function between the two groups(all P>0.05).The incidence of postoperative complications showed no significant difference[16.67%(4/24)vs 16.0%(4/25),P>0.05].All the 49 HCC patients were followed up after surgery(range:11.2

关键词： Hepatocellular carcinoma Laparoscopy Extra-Glissonian approach Intra-Glissonian approach Surgical efficiency Surgical safety

Downregulation of miR-181a-5p alleviates oxidative stress and inflammation in coronary microembolization-induced myocardial damage by directly targeting XIAP

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Journal of Geriatric Cardiology 2021年第6期18卷 426-439页

作者： You ZHOU Man-Yun LONG Zhi-Qing CHEN Jun-Wen HUANG Zhen-Bai QIN lang li Department of Cardiology the First Affiliated Hospital of Guangxi Medical UniversityNanningChina Guangxi Key Laboratory of Precision Medicine in Cardio-cerebrovascular Diseases Control and Prevention NanningChina

BACKGROUND Coronary microembolization(CME)is a complicated problem that commonly arises in the context of coronary *** play crucial roles in cardiovascular ***,the role and mechanism of miR-181a-5p in CME-induced myocardial injury remains *** We established CME rat *** function was detected by ***-basic fuchsin-picric acid staining was used to measure micro-infarction *** samples and cell culture supernatants were evaluated via enzyme-linked immunosorbent *** reactive oxygen species were determined by dichloro-dihydro-fluorescein diacetate assay,and the other oxidative stress related parameters were assayed by *** dual-luciferase reporter(DLR)assay and RNA pulldown were conducted to validate the association between miR-181a-5p and X-linked inhibitor of apoptosis protein(XIAP).The expression of miR-181a-5p and XIAP mRNA were determined by quantitative reverse transcription polymerase chain *** were evaluated via *** viability of the cell was evaluated via cell counting kit-8 *** The miR-181a-5p level was significantly increased in CME myocardial *** of miR-181a-5p improved CME-induced cardiac dysfunction and alleviated myocardial oxidative stress and inflammatory injury,whereas miR-181a-5p exhibited the opposite ***,the DLR assay and RNA pulldown results revealed that miR-181a-5p directly targeting on *** XIAP level was found to be remarkably decreased after *** overexpression attenuated CME-induced myocardial oxidative stress and inflammatory ***,in vitro rescue experiments revealed that knockdown of XIAP could abolish the protective effects of miR-181a-5p knockdown on hypoxia-induced cardiomyocyte oxidative stress and inflammatory *** Downregulation of miR-181a-5p alleviates CME-induced myocardial damage by suppressing myocardial oxidative stress and

关键词： damage XIAP Down

Changes of retinal vessel density in low to moderate myopic eyes with orthokeratology evaluated by optical coherence tomography angiography

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International Journal of Ophthalmology(English edition) 2023年第9期16卷 1512-1520页

作者： Jia-Hui Shi Yi-Ping Zhao Gang liu Xin-Yi Huang li-li lang Wan-Cheng Jia Ji-li Chen Medical College of Anhui University of Science and Technology Huainan 232000Anhui ProvinceChina South Hospital of the Sixth People’s Hospital Shanghai 201400China Shibei Hospital Shanghai 200435China

AIM:To explore the effect of orthokeratology(OK)fitting on retinal vessel density in low to moderate myopia adolescents by using optical coherence tomography ***:Children aged 10 to 14y with a cycloplegic spherical equivalent refraction of−0.50 diopter(D)to−5.00 D and astigmatism with more than−1.50 D were *** enrolled adolescents were divided into OK group and spectacle *** regular followup,adolescents were measured respectively at pre-wear,1,3,and 6mo after *** follow-up included uncorrected distance visual acuity(UDVA),axial length(AL),superficial capillary plexus density(SCPD),deep capillary plexus density(DCPD),central retinal thickness(CRT),foveal avascular zone area(FAZ-A),foveal avascular zone perimeter(FAZ-P)and foveal vessel density in a 300-μmwide region around foveal avascular zone(FD-300).The collected data were analyzed using statistical ***:By one month,SCPD significantly increased in the fovea and superior retina,and DCPD significantly increased inferiorly in OK group compared to spectacle group(P0.05).OK group showed a significant improvement in UDVA after wearing OK,compared to spectacle group(P0.05).CONCLUSION:Short-term OK worn can increase local retinal vessel density in adolescents with low-to-moderate myopia.

关键词： optical coherence tomography angiography orthokeratology myopia axial length retinal capillary plexus density

基于支板的超燃冲压发动机燃烧室模态转换过程参数化研究（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2018年第6期19卷 431-451页

作者： Lei liAO li YAN Wei HUANG lang-quan li Science and Technology on Scramjet Laboratory National University of Defense Technology

目的:超燃冲压发动机燃烧室中氢气的燃烧性能引起了研究者的广泛兴趣。本文旨在探讨不同压比下超燃冲压发动机燃烧室的燃烧性能以及壁面凹腔的影响,为双模态超燃冲压发动机燃烧室设计提供参考。创新点:1.研究压比变化过程中超燃向亚燃... 详细信息

目的:超燃冲压发动机燃烧室中氢气的燃烧性能引起了研究者的广泛兴趣。本文旨在探讨不同压比下超燃冲压发动机燃烧室的燃烧性能以及壁面凹腔的影响,为双模态超燃冲压发动机燃烧室设计提供参考。创新点:1.研究压比变化过程中超燃向亚燃的转换过程;2.研究壁面凹腔设置对模态转换过程的影响。方法:采用数值模拟方法研究不同来流条件下,压比和壁面凹腔设置对基于支板的超燃冲压发动机燃烧室中模态转换过程的影响。结论:1.壁面喷注压强对流场结构影响很大,特别是对于亚燃到超燃的模态转换过程和燃烧性能,当壁面喷注压强大约为支板喷注压强一半时,效果最好;2.壁面凹腔能帮助稳定流场,但也会带来一定的混合效率和燃烧效率损失,同时壁面凹腔能帮助延迟从超燃模态向亚燃模态的转换时间,这也从一定程度上说明带凹腔的燃烧室更加适合于超燃模态。

关键词：超燃冲压发动机模态转换支板凹腔燃烧性能

An hourly shallow landslide warning model developed by combining automatic landslide spatial susceptibility and temporal rainfall threshold predictions

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Journal of Mountain Science 2022年第12期19卷 3370-3387页

作者： CAO Yi-ming GUO Wei WU Yu-ming li lang-ping ZHANG Yi-xing LAN Heng-xing State Key Laboratory of Resources and Environmental Information System Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing100101China University of Chinese Academy of Sciences Beijing100049China Fujian Meteorological Service Centre Fuzhou350025China School of Geological Engineering and Geomatics Chang’an UniversityXi’an710064China Key Laboratory of Ecological Geology and Disaster Prevention of Ministry of Natural Resources Chang’an UniversityXi’an710064China Tianjin University of Commerce Tianjin300134China

Landslide warning models are important for mitigating landslide *** rainfall threshold model is the most widely used early warning model for predicting rainfall-triggered ***,the rainfall threshold model has been coupled with the landslide susceptibility(LS)model to improve the accuracy of early warnings in the spatial *** coupled models,designed based on a matrix including predefined rainfall thresholds and susceptibility levels,have been used to determine the warning *** predefined classifications inevitably have subjective rainfall thresholds and susceptibility levels,thus affecting the probability distribution information and eventually influencing the reliability of the produced early *** this paper,we propose a novel landslide warning model in which the temporal and spatial probabilities of landslides are coupled without predefining the classified *** temporal probability of landslides is obtained from the probability distribution of rainfall intensities that triggered historical *** spatial probability of landslides is then obtained from the susceptibility probability distribution.A case study shows that the proposed probability-coupled model can successfully provide hourly warning results before the occurrence of a *** all three models successfully predicted the landslide,the probability-coupled model produced a warning zone comprising the fewest grid ***,the probabilitycoupled model produced only 39 grid cells in the warning zone,while the rainfall threshold model and the matrix-coupled model produced warning zones including 81 and 49 grid cells,*** proposed model is also applicable to other regions affected by rainfall-induced landslides and is thus expected to be useful for practical landslide risk management.

关键词： Landslide Hourly warning Temporal probability Spatial probability Rainfall threshold Susceptibility

Expression of p53 in myocardium following coronary microembolization inrats and its significance

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Journal of Geriatric Cardiology 2017年第5期14卷 292-300页

作者： Yu-Han SUN Qiang SU lang li Xian-Tao WANG Yuan-Xi LU Jia-Bao liANG Department of Cardiology the First Affiliated Hospital of Guangxi Medical University Nanning China

Background Cardiomyocyte apoptosis is a primary cause for coronary microembolization （CME）-induced cardiac dysfunction, p53induces cell growth retardation and apoptosis through stress pathway. The present study investigated the mechanism of p53-induced myocar-dial apoptosis and cardiac dysfunction by activating the mitochondrion apoptotic pathway following CME. Methods Forty SD rats wereequally divided into microembolization （CME）, sham operation （sham）, CME＋siRNA-p53, and CME＋control-p53 groups. The CME ratmodel was established by injecting microembolization spheres via the left ventricle. Cardiac ultrasound, TUNEL, fluorescence quantitativePCR, and Western blot were used to assess the cardiac function indicators, cardiomyocyte apoptosis, and the expressions of mRNA and pro-tein in myocardial tissues, respectively. Results Echocardiography revealed a significantly reduced cardiac function of the CME group thanthe sham group while the CME-induced cardiac dysfunction was improved in the CME＋siRNA-p53 group. The indicators of myocardialapoptosis in the CME group increased significantly than the sham group; those of the CME＋siRNA-p53 group decreased significantly thanthe CME group. Fluorescence quantitative PCR and Western blot demonstrated that p53, Bbc3 （PUMA）, and cleaved caspase-3 expressionswere significantly increased, and BCL-2 expression was declined in myocardial tissues of the CME group compared to the sham group. Acontrasting result was observed in the CME＋siRNA-p53 group as compared to the CME group. Conclusions P53 is involved in theCME-induced cardiac dysfunction, which may up-regulate Bbc3 to activate BCL-2/caspase3 mitochondrial apoptotic pathway and inducemyocardial apoptosis. Inhibiting the p53 expression can effectively suppress this pathway, thereby reducing myocardial apoptosis and car-diac dysftmction.

关键词： Bbc3 BCL-2 Cardiac dysfunction Coronary microembolization Myocardial apoptosis p53

Nicorandil pretreatment inhibits myocardial apoptosis and improves cardiac function after coronary microembolization in rats

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Journal of Geriatric Cardiology 2018年第9期15卷 591-597页

作者： Wen-Kai HE Qiang SU Jiao-Bao liANG Xian-Tao WANG Yu-Han SUN lang li Department of Cardiology the First Affiliated Hospital of Guangxi Medical University Nanning China

Background Nicorandil （NIC） is a vasodilatory drug used to treat angina. However, its efficacy of cardioprotection in coronary mi- croembolization （CME） is largely unknown. This study was undertaken to determine whether nicorandil pretreatment could attenuate myo- cardial apoptosis and improve cardiac function after CME in rats. Methods Forty-five rats were randomly divided into a Sham group, a CME group and a CME ＋ NIC （NIC） group （n = 15 per group）. CME was established by injecting plastic microspheres （42 pm in diameter） into the left ventricle of the rats in all of the groups except the Sham group. The NIC group received nicorandil at 3 mg/kg per day for seven days before the operation. Cardiac fimction was assessed by echocardiography, the expression levels of cleaved caspase-9/8/3 were detected by Western blot, microinfarction area was measured by haematoxylin-basic fuchsin picric acid staining, and myocardial apoptosis was de- tected by TUNEL staining. Results Compared to that in the Sham group, cardiac fimction in the CME group was significantly decreased （P 〈 0.05）. However, compared to the CME group, the NIC group showed improved cardiac function （P 〈 0.05）. The expression levels of cleaved caspase-9/8/3 protein and myocardial apoptosis were dramatically increased in the CME group compared to those in the Sham group （P 〈 0.05）, while the NIC pretreatment group had significantly decreased expression levels of cleaved caspase-9/8/3 protein as well as a de- creased apoptotic rate （P 〈 0.05）. Conclusions NIC pretreatment inhibited CME-induced myocardial apoptosis and improved cardiac func- tion through blockade of the mitochondrial and death receptor-mediated apoptotic pathways.

关键词： Apoptosis Coronary microembolization Cardiac function Nicorandil

Implementation of PRINCE with resource-efficient structures based on FPGAs

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Frontiers of Information Technology & Electronic Engineering 2021年第11期22卷 1505-1516页

作者： lang li Jingya FENG Botao liU Ying GUO Qiuping li Hunan Provincial Key Laboratory of Intelligent Information Processing and Application Hengyang Normal UniversityHengyang421002China College of Information Science and Engineering Hunan Normal UniversityChangsha410081China College of Computer Science and Technology Hengyang Normal UniversityHengyang421002China

In this era of pervasive computing, low-resource devices have been deployed in various fields. PRINCE is a lightweight block cipher designed for low latency, and is suitable for pervasive computing applications. In this paper, we propose new circuit structures for PRINCE components by sharing and simplifying logic circuits, to achieve the goal of using a smaller number of logic gates to obtain the same result. Based on the new circuit structures of components and the best sharing among components,we propose three new hardware architectures for PRINCE. The architectures are simulated and synthesized on different programmable gate array devices. The results on Virtex-6 show that compared with existing architectures, the resource consumption of the unrolled, low-cost, and two-cycle architectures is reduced by 73, 119, and 380 slices, respectively. The low-cost architecture costs only 137 slices. The unrolled architecture costs 409 slices and has a throughput of 5.34 Gb/s. To our knowledge, for the hardware implementation of PRINCE, the new low-cost architecture sets new area records, and the new unrolled architecture sets new throughput records. Therefore, the newly proposed architectures are more resource-efficient and suitable for lightweight,latency-critical applications.

关键词： lightweight block cipher Field-programmable gate array(FPGA) Low-cost PRINCE Embedded security